UA89964C2 - 15β-ЗАМЕЩЕННЫЕ СТЕРОИДЫ, КОТОРЫЕ ИМЕЮТ СЕЛЕКТИВНУЮ ЭСТРОГЕННУЮ АКТИВНОСТЬ - Google Patents

15β-ЗАМЕЩЕННЫЕ СТЕРОИДЫ, КОТОРЫЕ ИМЕЮТ СЕЛЕКТИВНУЮ ЭСТРОГЕННУЮ АКТИВНОСТЬ

Info

Publication number: UA89964C2
Authority: UA; Ukraine
Prior art keywords: calkyl; ris; 15beta; estrogenic activity; substituted steroids
Prior art date: 2004-09-08

Application number

UAA200701655A

Other languages

English (en)

Ukrainian (uk)

Inventor

Губерт Ян Йозеф Лозен

Антониус Герардус Гендриксон Эдерван

Фредерикус Антониус Дейкс

Original Assignee

Н.В. Органон

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-09-08

Filing date

2005-05-09

Publication date

2010-03-25

2005-05-09 Application filed by Н.В. Органон filed Critical Н.В. Органон

2010-03-25 Publication of UA89964C2 publication Critical patent/UA89964C2/ru

Links

230000001076 estrogenic effect Effects 0.000 title 1
150000003431 steroids Chemical class 0.000 title 1
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical class 0.000 abstract 2
125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 abstract 1
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
102000015694 estrogen receptors Human genes 0.000 abstract 1
108010038795 estrogen receptors Proteins 0.000 abstract 1
125000005740 oxycarbonyl group Chemical group [*:1]OC([*:2])=O 0.000 abstract 1
230000003637 steroidlike Effects 0.000 abstract 1
125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Endocrinology (AREA)
Physical Education & Sports Medicine (AREA)
Diabetes (AREA)
Orthopedic Medicine & Surgery (AREA)
Reproductive Health (AREA)
Rheumatology (AREA)
Epidemiology (AREA)
Gynecology & Obstetrics (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

UAA200701655A 2004-09-08 2005-05-09 15β-ЗАМЕЩЕННЫЕ СТЕРОИДЫ, КОТОРЫЕ ИМЕЮТ СЕЛЕКТИВНУЮ ЭСТРОГЕННУЮ АКТИВНОСТЬ UA89964C2 (ru)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP04104334		2004-09-08

Publications (1)

Publication Number	Publication Date
UA89964C2 true UA89964C2 (ru)	2010-03-25

Family

ID=34929554

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
UAA200701655A UA89964C2 (ru)	2004-09-08	2005-05-09	15β-ЗАМЕЩЕННЫЕ СТЕРОИДЫ, КОТОРЫЕ ИМЕЮТ СЕЛЕКТИВНУЮ ЭСТРОГЕННУЮ АКТИВНОСТЬ

Country Status (20)

Country	Link
US (1)	US7838516B2 (ru)
EP (1)	EP1805201B1 (ru)
JP (1)	JP4889644B2 (ru)
AR (1)	AR050732A1 (ru)
AT (1)	ATE414710T1 (ru)
AU (1)	AU2005281705B2 (ru)
BR (1)	BRPI0514976A (ru)
CA (1)	CA2577497C (ru)
DK (1)	DK1805201T3 (ru)
ES (1)	ES2317312T3 (ru)
NZ (1)	NZ553266A (ru)
PE (1)	PE20060590A1 (ru)
PL (1)	PL1805201T3 (ru)
PT (1)	PT1805201E (ru)
RS (1)	RS51640B (ru)
RU (1)	RU2386637C2 (ru)
SI (1)	SI1805201T1 (ru)
TW (1)	TW200621795A (ru)
UA (1)	UA89964C2 (ru)
WO (1)	WO2006027347A1 (ru)

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US8288367B2 (en)	2006-11-30	2012-10-16	Solvay Pharmaceuticals Gmbh	Substituted estratriene derivatives as 17BETA HSD inhibitors
EP2448910B1 (en) *	2009-06-29	2013-05-15	Merz Pharma GmbH & Co. KGaA	Method of preparing neramexane
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CA2765610A1 (en) *	2009-06-29	2011-01-06	Merz Pharma Gmbh & Co. Kgaa	Method of preparing 3,3,5,5-tetramethylcyclohexanone
EP2383279A1 (en)	2011-07-19	2011-11-02	Pantarhei Bioscience B.V.	Process for the preparation of estetrol
LT2764008T (lt) *	2011-10-07	2016-11-10	Estetra S.P.R.L.	Estetrolio gamybos būdas
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JP6545266B2 (ja)	2014-12-23	2019-07-17	フォレンドファーマリミテッド	１７β‐ＨＳＤ１抑制剤のプロドラッグ
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ES2877186T3 (es)	2015-06-18	2021-11-16	Estetra Sprl	Comprimido orodispersable que contiene estetrol
MX385820B (es)	2015-06-18	2025-03-18	Estetra Sprl	Unidad de dosificacion orodispersable que contiene un componente estetrol.
EP3310346B1 (en)	2015-06-18	2021-03-24	Estetra SPRL	Orodispersible tablet containing estetrol
SI3310333T1 (sl)	2015-06-18	2020-08-31	Estetra Sprl	Orodisperzibilna enota odmerka, ki vsebuje komponento estetrola
CA3178291A1 (en)	2016-08-05	2018-04-12	Estetra Srl	Method for the management of dysmenorrhea and menstrual pain
PT3634975T (pt)	2017-06-08	2024-05-20	Organon R&D Finland Ltd	17-oximas de estra-1,3,5(10)-trien-17-onas 15.beta.-[3- propanamido]-substituídas para utilização na inibição de 17.beta.-hidroxiesteroide desidrogenases
TWI801561B (zh)	2018-04-19	2023-05-11	比利時商依思特拉私人有限責任公司	化合物及其用於緩解絕經相關症狀的用途
JOP20200260A1 (ar)	2018-04-19	2019-10-19	Estetra Sprl	مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث
CN113412269A (zh)	2018-12-05	2021-09-17	佛恩多制药有限公司	作为17-hsd1抑制剂的在位置16(17)具有缩合的吡唑环的雌甾-1,3,5(10)-三烯化合物

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2005
- 2005-05-09 UA UAA200701655A patent/UA89964C2/ru unknown
- 2005-09-02 TW TW094130148A patent/TW200621795A/zh unknown
- 2005-09-05 NZ NZ553266A patent/NZ553266A/en not_active IP Right Cessation
- 2005-09-05 ES ES05794597T patent/ES2317312T3/es active Active
- 2005-09-05 JP JP2007530702A patent/JP4889644B2/ja not_active Expired - Fee Related
- 2005-09-05 EP EP05794597A patent/EP1805201B1/en active Active
- 2005-09-05 RU RU2007112939/04A patent/RU2386637C2/ru not_active IP Right Cessation
- 2005-09-05 BR BRPI0514976-2A patent/BRPI0514976A/pt not_active IP Right Cessation
- 2005-09-05 AU AU2005281705A patent/AU2005281705B2/en not_active Ceased
- 2005-09-05 WO PCT/EP2005/054368 patent/WO2006027347A1/en active Application Filing
- 2005-09-05 SI SI200530582T patent/SI1805201T1/sl unknown
- 2005-09-05 PT PT05794597T patent/PT1805201E/pt unknown
- 2005-09-05 DK DK05794597T patent/DK1805201T3/da active
- 2005-09-05 PL PL05794597T patent/PL1805201T3/pl unknown
- 2005-09-05 CA CA2577497A patent/CA2577497C/en not_active Expired - Fee Related
- 2005-09-05 US US11/662,166 patent/US7838516B2/en active Active
- 2005-09-05 RS RS20070075A patent/RS51640B/en unknown
- 2005-09-05 AT AT05794597T patent/ATE414710T1/de active
- 2005-09-06 PE PE2005001026A patent/PE20060590A1/es not_active Application Discontinuation
- 2005-09-08 AR ARP050103745A patent/AR050732A1/es unknown

Also Published As

Publication number	Publication date
ATE414710T1 (de)	2008-12-15
EP1805201B1 (en)	2008-11-19
AR050732A1 (es)	2006-11-15
RS51640B (en)	2011-10-31
ES2317312T3 (es)	2009-04-16
PE20060590A1 (es)	2006-07-14
BRPI0514976A (pt)	2008-07-01
EP1805201A1 (en)	2007-07-11
PT1805201E (pt)	2008-12-31
SI1805201T1 (sl)	2009-04-30
RU2386637C2 (ru)	2010-04-20
RU2007112939A (ru)	2008-11-10
PL1805201T3 (pl)	2009-04-30
JP2008512426A (ja)	2008-04-24
TW200621795A (en)	2006-07-01
CA2577497A1 (en)	2006-03-16
US20070254860A1 (en)	2007-11-01
AU2005281705A1 (en)	2006-03-16
DK1805201T3 (da)	2009-01-12
US7838516B2 (en)	2010-11-23
WO2006027347A1 (en)	2006-03-16
RS20070075A (en)	2008-09-29
JP4889644B2 (ja)	2012-03-07
NZ553266A (en)	2009-06-26
CA2577497C (en)	2012-03-20
AU2005281705B2 (en)	2011-03-10

Publication	Publication Date	Title
UA89964C2 (ru)	2010-03-25	15β-ЗАМЕЩЕННЫЕ СТЕРОИДЫ, КОТОРЫЕ ИМЕЮТ СЕЛЕКТИВНУЮ ЭСТРОГЕННУЮ АКТИВНОСТЬ
PL1995242T3 (pl)	2013-03-29	Nowa pochodna 1,2,3,4-tetrahydrochinoksaliny, mająca aktywność wiążącą receptor glukokortykoidowy
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MXPA06001592A (es)	2006-05-19	Derivados de (4-hidroxifenil)-1h-indol-3-carbaldehido oxima como agentes estrogenicos.
IL190137A0 (en)	2008-08-07	Crystals of laquinimod sodium, and process for the manufacture thereof
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WO2003082894A3 (en)	2004-04-15	C-17 spirolactonization and 6,7 oxidation of steroids
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TW200716130A (en)	2007-05-01	Purified form of tanaproget
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DK1353938T3 (da)	2008-05-26	Androgene, 7-substituerede, 11-halogenerede steroider
DE602004026571D1 (en)	2010-05-27	Cyclisches aminophenylsulfamatderivativ
WO2006056304A3 (en)	2007-01-25	Control of indoleamine 2,3 deoxygenase expression and activity
MY143679A (en)	2011-06-30	15b-subsitituded streoids having selective estrogenic activity
HK1055059A2 (en)	2003-12-05	5-SUBSTITUTED 7,9-DIFLUORO-5H-CHROMENO[3,4-f]QUINOLINE COMPOUNDS AS SELECTIVE PROGESTERONE RECEPTOR MODULATOR COMPOUNDS
MX2007007347A (es)	2007-07-13	Usos nevodosos para agonistas de estrogeno beta.
ATE417055T1 (de)	2008-12-15	Steroid modifizierte solatriosen