+

SV2006002274A - Derivados de 2-amido-4-feniltiazol, su preparacion y su aplicacion en terapeutica - Google Patents

Derivados de 2-amido-4-feniltiazol, su preparacion y su aplicacion en terapeutica

Info

Publication number
SV2006002274A
SV2006002274A SV2005002274A SV2005002274A SV2006002274A SV 2006002274 A SV2006002274 A SV 2006002274A SV 2005002274 A SV2005002274 A SV 2005002274A SV 2005002274 A SV2005002274 A SV 2005002274A SV 2006002274 A SV2006002274 A SV 2006002274A
Authority
SV
El Salvador
Prior art keywords
amido
therapeutics
derivatives
phenyltiazol
preparation
Prior art date
Application number
SV2005002274A
Other languages
English (en)
Inventor
Pierre Casellas
Daniel Floutard
Pierre Fraisse
Samir Jegham
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of SV2006002274A publication Critical patent/SV2006002274A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

LA INVENCIÓN TIENE COMO OBJETO DERIVADOS DE 2-AMIDO-4-FENITIAZOL, DE FORMULA GENERAL (I) SIGUIENTE (VER FORMULA) EN EL ESTADO DE BASE O DE SAL DE ADICIÓN A UN ACIDO FARMACEUTICAMENTE ACEPTABLE, EN ESTADO DE HIDRATOS O DE SOLVATOS, ASÍ COMO EN FORMA DE ENANTIOMEROS, DE DIASTEREOISOMEROS Y SU MEZCLA.IGUALMENTE, LA INVENCIÓN TIENE POR OBJETO COMPOSICIONES FARMACEUTICAS QUE CONTIENEN UN COMPUESTO DE FORMULA GENERAL (I) Y DE SU UTILIZACIÓN EN TERAPEUTICA
SV2005002274A 2004-10-19 2005-10-19 Derivados de 2-amido-4-feniltiazol, su preparacion y su aplicacion en terapeutica SV2006002274A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0411083A FR2876692B1 (fr) 2004-10-19 2004-10-19 Derives de 2-amido-4-phenylthiazole, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
SV2006002274A true SV2006002274A (es) 2006-06-28

Family

ID=34950743

Family Applications (1)

Application Number Title Priority Date Filing Date
SV2005002274A SV2006002274A (es) 2004-10-19 2005-10-19 Derivados de 2-amido-4-feniltiazol, su preparacion y su aplicacion en terapeutica

Country Status (27)

Country Link
US (1) US7598392B2 (es)
EP (1) EP1807421B1 (es)
JP (1) JP2008517042A (es)
KR (1) KR20070085395A (es)
CN (1) CN101065376A (es)
AR (1) AR051334A1 (es)
AT (1) ATE502035T1 (es)
AU (1) AU2005296958A1 (es)
BR (1) BRPI0518231A2 (es)
CA (1) CA2584774A1 (es)
DE (1) DE602005026964D1 (es)
EA (1) EA200700901A1 (es)
EC (1) ECSP077402A (es)
FR (1) FR2876692B1 (es)
GT (1) GT200500292A (es)
IL (1) IL182624A0 (es)
MA (1) MA29017B1 (es)
MX (1) MX2007004740A (es)
NO (1) NO20072515L (es)
PA (1) PA8649901A1 (es)
PE (1) PE20060585A1 (es)
SV (1) SV2006002274A (es)
TN (1) TNSN07145A1 (es)
TW (1) TW200630364A (es)
UY (1) UY29169A1 (es)
WO (1) WO2006042954A1 (es)
ZA (1) ZA200703876B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2854158B1 (fr) 2003-04-25 2006-11-17 Sanofi Synthelabo Derives de 2-acylamino-4-phenylethiazole, leur preparation et leur application en therapeutique
FR2872813B1 (fr) 2004-07-09 2007-01-19 Sanofi Synthelabo Derives de 2-carbamide-4-phenylthiazole, leur preparation et leur application en therapeutique
CN101331125A (zh) * 2005-12-12 2008-12-24 健亚生物科技公司 N-(5-元杂芳香环)-酰胺基抗病毒化合物
FR2895989B1 (fr) 2006-01-06 2010-04-30 Sanofi Aventis Derives de 2-carbamide-4-phenylthiazole, leur preparation et leur application en therapeutique
WO2009076404A1 (en) * 2007-12-10 2009-06-18 Epix Delaware, Inc. Carboxamide compounds and their use as antagonists of the chemokine ccr2 receptor
BRPI0820701A2 (pt) 2007-12-11 2015-06-16 Cytopathfinder Inc Composto de carboxamida e seu uso como agonistas do receptor de quimiocina
WO2010007046A2 (en) 2008-07-15 2010-01-21 Novartis Ag Organic compounds
JO3346B1 (ar) * 2008-12-22 2019-03-13 Chemocentryx Inc مواد مضادة C5aR
AP2013006986A0 (en) 2011-01-04 2013-07-31 Novartis Ag Indole compounds or analogues thereof useful for the treatment of age-related macular degeneration (AMD)
EP2867226B1 (en) 2012-06-28 2018-11-14 Novartis AG Complement pathway modulators and uses thereof
EP2867229B1 (en) 2012-06-28 2017-07-26 Novartis AG Pyrrolidine derivatives and their use as complement pathway modulators
US9487483B2 (en) 2012-06-28 2016-11-08 Novartis Ag Complement pathway modulators and uses thereof
EP2867225B1 (en) 2012-06-28 2017-08-09 Novartis AG Pyrrolidine derivatives and their use as complement pathway modulators
WO2014002053A1 (en) 2012-06-28 2014-01-03 Novartis Ag Pyrrolidine derivatives and their use as complement pathway modulators
EA201590200A1 (ru) 2012-07-12 2015-08-31 Новартис Аг Модуляторы пути активации комплемента и их применение
EP4114529A1 (en) 2020-03-03 2023-01-11 PIC Therapeutics, Inc. Eif4e inhibitors and uses thereof
JP2024534127A (ja) 2021-08-25 2024-09-18 ピク セラピューティクス， インコーポレイテッド ｅＩＦ４Ｅ阻害剤及びその使用
US12157732B2 (en) 2021-08-25 2024-12-03 PIC Therapeutics, Inc. eIF4E inhibitors and uses thereof
KR20240140019A (ko) * 2023-03-15 2024-09-24 현대약품 주식회사 신규한 화합물, 및 이를 포함하는 약학적 조성물

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2146898A (en) * 1937-12-06 1939-02-14 Int Harvester Co Potato digger
FR2406634A1 (fr) * 1977-10-19 1979-05-18 Fabre Sa Pierre Immunostimulants derives d'amino thiazoles
FR2677356B1 (fr) 1991-06-05 1995-03-17 Sanofi Sa Derives heterocycliques d'acylamino-2 thiazoles-5 substitues, leur preparation et compositions pharmaceutiques en contenant.
JPH07502014A (ja) 1991-06-21 1995-03-02 ベーリンガー　マンハイム　イタリア　エス．ピー．エイ． 気道に対して抗喘息性、抗炎症性活性を有する２−アミノ−４−アリール−チアゾール
US6506751B1 (en) * 1999-11-12 2003-01-14 Millennium Pharmaceuticals, Inc. Thiazolidinone compounds useful as chemokine inhibitors
US6852752B2 (en) * 1999-12-17 2005-02-08 Vicuron Pharmaceuticals Inc. Urea compounds, compositions and methods of use and preparation
US6797820B2 (en) * 1999-12-17 2004-09-28 Vicuron Pharmaceuticals Inc. Succinate compounds, compositions and methods of use and preparation
EP1344525A4 (en) * 2000-12-22 2005-05-25 Ishihara Sangyo Kaisha ANILINE DERIVATIVES OR ITS SALTS AND CYTOKINE PRODUCTION INHIBITORS CONTAINING THEM
WO2003015778A1 (en) 2001-08-17 2003-02-27 Merck & Co., Inc. Tyrosine kinase inhibitors
TW200403058A (en) * 2002-04-19 2004-03-01 Bristol Myers Squibb Co Heterocyclo inhibitors of potassium channel function
FR2854158B1 (fr) * 2003-04-25 2006-11-17 Sanofi Synthelabo Derives de 2-acylamino-4-phenylethiazole, leur preparation et leur application en therapeutique
AR044098A1 (es) 2003-04-30 2005-08-24 Hoffmann La Roche Derivados de anilina, su elaboracion, composiciones farmaceuticas y su uso para elaborar medicamentos para el tratamiento del cancer
FR2872813B1 (fr) 2004-07-09 2007-01-19 Sanofi Synthelabo Derives de 2-carbamide-4-phenylthiazole, leur preparation et leur application en therapeutique
RU2423349C2 (ru) 2004-12-24 2011-07-10 Астразенека Аб Гетероциклические соединения в качестве антагонистов ccr2b
FR2895989B1 (fr) 2006-01-06 2010-04-30 Sanofi Aventis Derives de 2-carbamide-4-phenylthiazole, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
NO20072515L (no) 2007-06-28
FR2876692B1 (fr) 2007-02-23
ZA200703876B (en) 2008-12-31
CN101065376A (zh) 2007-10-31
JP2008517042A (ja) 2008-05-22
US7598392B2 (en) 2009-10-06
MX2007004740A (es) 2007-06-18
WO2006042954A1 (fr) 2006-04-27
AU2005296958A1 (en) 2006-04-27
ATE502035T1 (de) 2011-04-15
EP1807421B1 (fr) 2011-03-16
EP1807421A1 (fr) 2007-07-18
PE20060585A1 (es) 2006-08-18
CA2584774A1 (fr) 2006-04-27
MA29017B1 (fr) 2007-11-01
DE602005026964D1 (de) 2011-04-28
GT200500292A (es) 2006-05-11
KR20070085395A (ko) 2007-08-27
WO2006042954A8 (fr) 2008-03-13
IL182624A0 (en) 2007-07-24
US20070259847A1 (en) 2007-11-08
TW200630364A (en) 2006-09-01
ECSP077402A (es) 2007-05-30
FR2876692A1 (fr) 2006-04-21
EA200700901A1 (ru) 2007-10-26
TNSN07145A1 (fr) 2008-11-21
UY29169A1 (es) 2006-05-31
PA8649901A1 (es) 2006-06-02
AR051334A1 (es) 2007-01-03
BRPI0518231A2 (pt) 2008-11-11

Similar Documents

Publication Publication Date Title
ECSP077402A (es) Derivados de 2-amido-4-feniltiazol, su preparación y su aplicación en terapéutica
ECSP067110A (es) Derivados de 2-carbamida-4-feniltiazol, su preparación y su aplicación en terapéutica
CR8842A (es) Derivados de pirido-pirimidina, su preparacion, su aplicacion en terapeutica
TW200628161A (en) Novel betulin derivatives, preparation thereof and use thereof
MX2009000871A (es) Novedosos inhibidores de transcriptasa inversa de vih.
UY30440A1 (es) Nuevos compuestos
ECSP077316A (es) Compuestos imidazo-3-il-amina bicíclicos sustituidos
TW200745122A (en) New compounds I
ECSP055671A (es) Nuevas quinazolinonas espirocondensadas y su uso como inhibidores de la fosfodiesteresa
ECSP066541A (es) Nuevos derivados de piridazin-3(2h)-ona
MX2009013830A (es) Compuestos antivirales.
UA98494C2 (uk) Противірусні сполуки
CR10479A (es) Modulares bencimidazolicos de vr1
GT200500363A (es) 3-amino-pirazol [3,4b] piridinas con inhibidores de proteintirosinquinasas, su preparacion y uso como medicamento.
UY29857A1 (es) Derivados de la 4-amino-quinazolina, su preparación y su aplicación en terapéutica.
UA93709C2 (ru) 12-имидазолил-1-додеканол и его применение b изготовлении фармацевтических композиций
TW200745024A (en) Carboxamide derivatives as muscarinic receptor antagonists
SG158091A1 (en) Imidazoazepinone compounds
ATE443722T1 (de) Peptide und peptidderivate, ihre herstellung sowie ihre verwendung zur herstellung einer therapeutisch und/oder prophylaktisch wirksamen pharmazeutischen zusammensetzung
MX2012000103A (es) Nuevos derivados de 1,2,3,4-tetrahidro-pirimido (1,2-a) pirimidin-6-ona, su preparacion y su uso farmaceutica.
UA103329C2 (ru) Соли соединений-ингибиторов вич
TW200745133A (en) New compounds II
ATE474574T1 (de) Imidazoazephinonverbindungen
DE602007005387D1 (de) Ptors
CR10098A (es) Derivados de 2-carbamida-4-feniltiazol, su preparacion y su aplicacion en terapeutica
点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载