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SV1999000060A - Procedimiento para la preparacion de (s,s)-bencil-2,8-diazabiciclo 4.3.0 nonano ref. 32965-sv - Google Patents

Procedimiento para la preparacion de (s,s)-bencil-2,8-diazabiciclo 4.3.0 nonano ref. 32965-sv

Info

Publication number
SV1999000060A
SV1999000060A SV1999000060A SV1999000060A SV1999000060A SV 1999000060 A SV1999000060 A SV 1999000060A SV 1999000060 A SV1999000060 A SV 1999000060A SV 1999000060 A SV1999000060 A SV 1999000060A SV 1999000060 A SV1999000060 A SV 1999000060A
Authority
SV
El Salvador
Prior art keywords
diazabiciclo
bencil
nonano
procedure
preparation
Prior art date
Application number
SV1999000060A
Other languages
English (en)
Inventor
Peter Fey
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of SV1999000060A publication Critical patent/SV1999000060A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UN PROCEDIMIENTO PARA LA PREPARACION DE (S,S)-8-BENCIL-2,8-DIAZABICICLO [4.3.0]NONANO.
SV1999000060A 1998-05-11 1999-05-11 Procedimiento para la preparacion de (s,s)-bencil-2,8-diazabiciclo 4.3.0 nonano ref. 32965-sv SV1999000060A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19821039A DE19821039A1 (de) 1998-05-11 1998-05-11 Verfahren zur Herstellung von (S,S)-Benzyl-2,8-diazabicyclo[4.3.0]nonan

Publications (1)

Publication Number Publication Date
SV1999000060A true SV1999000060A (es) 1999-10-27

Family

ID=7867389

Family Applications (1)

Application Number Title Priority Date Filing Date
SV1999000060A SV1999000060A (es) 1998-05-11 1999-05-11 Procedimiento para la preparacion de (s,s)-bencil-2,8-diazabiciclo 4.3.0 nonano ref. 32965-sv

Country Status (13)

Country Link
US (1) US6235908B1 (es)
EP (1) EP1077979B1 (es)
JP (1) JP4554076B2 (es)
AR (1) AR019123A1 (es)
AU (1) AU3824599A (es)
CA (1) CA2331526C (es)
CO (1) CO4830459A1 (es)
DE (2) DE19821039A1 (es)
ES (1) ES2245101T3 (es)
PE (1) PE20000477A1 (es)
SV (1) SV1999000060A (es)
UY (1) UY25501A1 (es)
WO (1) WO1999058532A1 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ302015B6 (cs) * 1999-10-08 2010-09-08 Affinium Pharmaceuticals, Inc. Inhibitory Fab I
US6476046B1 (en) 2000-12-04 2002-11-05 Sepracor, Inc. Diazabicyclo[4.3.0]nonanes, and methods of use thereof
JP4387804B2 (ja) * 2001-04-06 2009-12-24 アフィニアム・ファーマシューティカルズ・インコーポレイテッド ＦａｂＩ阻害剤
JP4859460B2 (ja) 2002-12-06 2012-01-25 アフィニウム ファーマシューティカルズ， インク． ヘテロ環化合物、その製造方法および治療におけるその使用
ATE409485T1 (de) 2003-03-17 2008-10-15 Affinium Pharm Inc Pharmazeutische zusammensetzungen inhibitoren von fab i und weitere antibiotika enthaltend
EP1828167B1 (en) * 2004-06-04 2014-08-06 Debiopharm International SA Acrylamide derivatives as antibiotic agents
CA2632476A1 (en) * 2005-12-05 2007-06-14 Affinium Pharmaceuticals, Inc. Heterocyclylacrylamide compounds as fabi inhibitors and antibacterial agents
JP5468899B2 (ja) 2006-07-20 2014-04-09 アフィニウム ファーマシューティカルズ， インク． Ｆａｂｉインヒビターとしてのアクリルアミド誘導体
KR20150048920A (ko) * 2006-11-13 2015-05-07 씨아이피엘에이 엘티디. 목시플록사신 염산염의 합성방법
US7692015B2 (en) * 2007-01-05 2010-04-06 Zheqing Wang Economical process for preparing (S, S)-2, 8-diazabicyclo[4.3.0]nonane and its enantiomer
WO2008098374A1 (en) * 2007-02-16 2008-08-21 Affinium Pharmaceuticals, Inc. Salts, prodrugs and polymorphs of fab i inhibitors
WO2009125425A2 (en) * 2008-02-08 2009-10-15 Neuland Laboratories Ltd Improved process for the preparation of (s.s)-2.8-diazabicyclo[4.3.0]nonane
IT1393337B1 (it) 2009-03-06 2012-04-20 Italiana Sint Spa Sintesi di (4as, 7as)-ottaidro-1h-pirrolo[3,4-b]piridina
CN103044418B (zh) * 2011-10-14 2015-02-04 上海朴颐化学科技有限公司 (s,s)-2,8-二氮杂双环[4,3,0]壬烷的不对称合成方法、相关原料及制备方法
EP2861608B8 (en) 2012-06-19 2019-06-19 Debiopharm International SA Prodrug derivatives of (e)-n-methyl-n-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide
DK3419628T3 (da) 2016-02-26 2021-01-11 Debiopharm Int Sa Medikament til behandling af diabetiske fodinfektioner
CN112574197B (zh) * 2020-12-07 2021-12-31 泰安汉威集团有限公司 一种化合物c的手性纯化方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB354975A (en) 1929-07-19 1931-08-20 Ig Farbenindustrie Ag Manufacture of optically active phenylpropanol-methylamines
HU194221B (en) * 1985-04-19 1988-01-28 Richter Gedeon Vegyeszet Process for preparing novel octahydro-indolo/2,3-a/quinoline derivative and pharmaceutical comprising this compound
JPH0285235A (ja) * 1988-09-22 1990-03-26 Kohjin Co Ltd 光学活性アミノアルコール類の製法
JP2995704B2 (ja) * 1989-02-17 1999-12-27 東京化成工業株式会社 光学活性な１ｈ−３−アミノピロリジン化合物の製造法
IT1231158B (it) 1989-07-20 1991-11-19 Dompe Farmaceutici Spa Procedimento per la risoluzione ottica della dropropizina.
WO1992013858A1 (en) 1991-01-31 1992-08-20 Pfizer Inc. Resolution of trans-2-(2-pyrimidinyl)-7-(hydroxymethyl)octahydro-2h-pyrido[1,2-a]pyrazine
TW209865B (es) * 1992-01-10 1993-07-21 Bayer Ag
DE4234078A1 (de) 1992-10-09 1994-04-14 Bayer Ag Chinoloncarbonsäuren
DE4234330A1 (de) 1992-10-12 1994-04-14 Bayer Ag Chinoloncarbonsäuren
JP3268098B2 (ja) * 1992-12-25 2002-03-25 第一製薬株式会社 二環性環状アミン誘導体
US5686614A (en) 1995-04-11 1997-11-11 Neurogen Corporation Preparation of chiral 5-aminocarbonyl-5H-dibenzo a,d!cyclohepten-5,10-imines by optical resolution
DE19601745C1 (de) 1996-01-19 1997-10-09 Gruenenthal Gmbh Verfahren zur Racematspaltung von Tramadol

Also Published As

Publication number Publication date
PE20000477A1 (es) 2000-07-07
CA2331526C (en) 2011-09-13
CA2331526A1 (en) 1999-11-18
JP4554076B2 (ja) 2010-09-29
UY25501A1 (es) 1999-11-17
AU3824599A (en) 1999-11-29
US6235908B1 (en) 2001-05-22
ES2245101T3 (es) 2005-12-16
DE59912242D1 (de) 2005-08-11
JP2002514648A (ja) 2002-05-21
AR019123A1 (es) 2001-12-26
DE19821039A1 (de) 1999-11-18
WO1999058532A1 (de) 1999-11-18
CO4830459A1 (es) 1999-08-30
EP1077979B1 (de) 2005-07-06
EP1077979A1 (de) 2001-02-28

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