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SG11202101618PA - Arginase inhibitors and methods of use thereof - Google Patents

Arginase inhibitors and methods of use thereof

Info

Publication number
SG11202101618PA
SG11202101618PA SG11202101618PA SG11202101618PA SG11202101618PA SG 11202101618P A SG11202101618P A SG 11202101618PA SG 11202101618P A SG11202101618P A SG 11202101618PA SG 11202101618P A SG11202101618P A SG 11202101618PA SG 11202101618P A SG11202101618P A SG 11202101618PA
Authority
SG
Singapore
Prior art keywords
methods
arginase inhibitors
arginase
inhibitors
Prior art date
Application number
SG11202101618PA
Inventor
Dedong Wu
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of SG11202101618PA publication Critical patent/SG11202101618PA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/22Boron compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/69Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG11202101618PA 2018-08-22 2019-08-21 Arginase inhibitors and methods of use thereof SG11202101618PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862721113P 2018-08-22 2018-08-22
PCT/EP2019/072341 WO2020038983A1 (en) 2018-08-22 2019-08-21 Arginase inhibitors and methods of use thereof

Publications (1)

Publication Number Publication Date
SG11202101618PA true SG11202101618PA (en) 2021-03-30

Family

ID=67742403

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202101618PA SG11202101618PA (en) 2018-08-22 2019-08-21 Arginase inhibitors and methods of use thereof

Country Status (25)

Country Link
US (1) US11952392B2 (en)
EP (2) EP4371614A3 (en)
JP (1) JP7441210B2 (en)
KR (1) KR102668252B1 (en)
CN (1) CN112584900B (en)
AU (1) AU2019323663B2 (en)
CA (1) CA3109100A1 (en)
CL (1) CL2021000430A1 (en)
DK (1) DK3840837T3 (en)
EA (1) EA202190532A1 (en)
ES (1) ES2980252T3 (en)
FI (1) FI3840837T3 (en)
HR (1) HRP20240694T1 (en)
HU (1) HUE066903T2 (en)
IL (1) IL280924B2 (en)
LT (1) LT3840837T (en)
MA (1) MA53427B1 (en)
MX (1) MX2021002042A (en)
PL (1) PL3840837T3 (en)
PT (1) PT3840837T (en)
RS (1) RS65608B1 (en)
SG (1) SG11202101618PA (en)
SI (1) SI3840837T1 (en)
SM (1) SMT202400221T1 (en)
WO (1) WO2020038983A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI877770B (en) 2018-02-27 2025-03-21 美商英塞特公司 Imidazopyrimidines and triazolopyrimidines as a2a / a2b inhibitors
US11168089B2 (en) 2018-05-18 2021-11-09 Incyte Corporation Fused pyrimidine derivatives as A2A / A2B inhibitors
CR20240054A (en) 2018-07-05 2024-02-26 Incyte Corp FUSED PYRAZINE DERIVATIVES AS A2A/A2B INHIBITORS (Div. 2021-71)
TWI829857B (en) 2019-01-29 2024-01-21 美商英塞特公司 Pyrazolopyridines and triazolopyridines as a2a / a2b inhibitors
AU2020218651B2 (en) 2019-02-08 2023-01-12 Astrazeneca Ab Arginase inhibitors and methods of use thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2586219C2 (en) 2010-04-22 2016-06-10 Марс, Инкорпорейтед Arginase inhibitors and therapeutic use thereof
MX385315B (en) * 2015-06-23 2025-03-14 Calithera Biosciences Inc COMPOSITIONS AND METHODS FOR INHIBITING ARGINASE ACTIVITY.
TW201828959A (en) * 2016-11-08 2018-08-16 美商卡利泰拉生物科技公司 Arginine inhibitor combination therapy
EP3559009B1 (en) * 2016-12-22 2021-04-07 Calithera Biosciences, Inc. Compositions and methods for inhibiting arginase activity
US11420984B2 (en) 2018-02-17 2022-08-23 Astrazeneca Ab Arginase inhibitors and methods of use thereof
EP3765006A4 (en) 2018-03-13 2022-02-23 Merck Sharp & Dohme Corp. Arginase inhibitors and methods of use
WO2019205979A1 (en) 2018-04-27 2019-10-31 四川科伦博泰生物医药股份有限公司 Non-natural amino acid derivative, pharmaceutical composition comprising same, method for preparing same, and use of same

Also Published As

Publication number Publication date
EA202190532A1 (en) 2021-07-08
EP4371614A2 (en) 2024-05-22
FI3840837T3 (en) 2024-06-03
LT3840837T (en) 2024-06-10
KR102668252B1 (en) 2024-05-21
HUE066903T2 (en) 2024-09-28
CN112584900A (en) 2021-03-30
IL280924B2 (en) 2024-10-01
CL2021000430A1 (en) 2021-09-03
SMT202400221T1 (en) 2024-07-09
PT3840837T (en) 2024-06-14
KR20210049120A (en) 2021-05-04
EP4371614A3 (en) 2025-09-24
JP7441210B2 (en) 2024-02-29
CA3109100A1 (en) 2020-02-27
IL280924A (en) 2021-04-29
EP3840837A1 (en) 2021-06-30
MA53427B1 (en) 2024-06-28
JP2021535111A (en) 2021-12-16
HRP20240694T1 (en) 2024-08-16
CN112584900B (en) 2025-07-15
EP3840837B1 (en) 2024-03-20
MA53427A (en) 2021-12-01
AU2019323663B2 (en) 2022-07-14
US20210332068A1 (en) 2021-10-28
RS65608B1 (en) 2024-07-31
US11952392B2 (en) 2024-04-09
WO2020038983A1 (en) 2020-02-27
DK3840837T3 (en) 2024-06-10
AU2019323663A1 (en) 2021-04-08
PL3840837T3 (en) 2024-08-19
SI3840837T1 (en) 2024-07-31
ES2980252T3 (en) 2024-09-30
MX2021002042A (en) 2021-04-28
IL280924B1 (en) 2024-06-01

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