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SG11201706826VA - Method for separating cells, and device therefor - Google Patents

Method for separating cells, and device therefor

Info

Publication number
SG11201706826VA
SG11201706826VA SG11201706826VA SG11201706826VA SG11201706826VA SG 11201706826V A SG11201706826V A SG 11201706826VA SG 11201706826V A SG11201706826V A SG 11201706826VA SG 11201706826V A SG11201706826V A SG 11201706826VA SG 11201706826V A SG11201706826V A SG 11201706826VA
Authority
SG
Singapore
Prior art keywords
device therefor
separating cells
separating
cells
therefor
Prior art date
Application number
SG11201706826VA
Inventor
Noriaki Arai
Original Assignee
Toppan Printing Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toppan Printing Co Ltd filed Critical Toppan Printing Co Ltd
Publication of SG11201706826VA publication Critical patent/SG11201706826VA/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302Apparatus specially adapted for immunological test procedures
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04Cell isolation or sorting
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/02Separating microorganisms from their culture media
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0647Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0652Sorting or classification of particles or molecules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0816Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0877Flow chambers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/08Regulating or influencing the flow resistance
    • B01L2400/084Passive control of flow resistance
    • B01L2400/086Passive control of flow resistance using baffles or other fixed flow obstructions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pathology (AREA)
  • Wood Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Fluid Mechanics (AREA)
  • Dispersion Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Clinical Laboratory Science (AREA)
  • Biophysics (AREA)
  • Ecology (AREA)
  • Sustainable Development (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
SG11201706826VA 2015-02-27 2016-02-26 Method for separating cells, and device therefor SG11201706826VA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2015038916 2015-02-27
JP2015193590 2015-09-30
PCT/JP2016/001055 WO2016136273A1 (en) 2015-02-27 2016-02-26 Method for separating cells, and device therefor

Publications (1)

Publication Number Publication Date
SG11201706826VA true SG11201706826VA (en) 2017-09-28

Family

ID=56789289

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201706826VA SG11201706826VA (en) 2015-02-27 2016-02-26 Method for separating cells, and device therefor

Country Status (6)

Country Link
US (1) US10996216B2 (en)
EP (1) EP3263693A4 (en)
JP (3) JPWO2016136273A1 (en)
CN (1) CN107250343B (en)
SG (1) SG11201706826VA (en)
WO (1) WO2016136273A1 (en)

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US20150064153A1 (en) 2013-03-15 2015-03-05 The Trustees Of Princeton University High efficiency microfluidic purification of stem cells to improve transplants
CN110186835B (en) 2013-03-15 2022-05-31 Gpb科学有限公司 On-chip microfluidic processing of particles
CN105247042B (en) 2013-03-15 2021-06-11 普林斯顿大学理事会 Method and apparatus for high throughput purification
EP3263693A4 (en) * 2015-02-27 2018-02-21 Toppan Printing Co., Ltd. Method for separating cells, and device therefor
US10976232B2 (en) 2015-08-24 2021-04-13 Gpb Scientific, Inc. Methods and devices for multi-step cell purification and concentration
JP2020503887A (en) * 2016-10-24 2020-02-06 ジーピービー・サイエンティフィック・リミテッド・ライアビリティ・カンパニーGpb Scientific, Llc Deterministic transverse substitution in the preparation of therapeutic cells and compositions
JP2020500023A (en) * 2016-11-18 2020-01-09 ニュー ヨーク ステム セル ファウンデーション,インコーポレイテッド Microfluidic systems and methods of use
EP4005675B1 (en) * 2017-06-20 2024-07-31 Redbud Labs, Inc. Methods of making modular active surface devices for microfluidic systems
US10844353B2 (en) * 2017-09-01 2020-11-24 Gpb Scientific, Inc. Methods for preparing therapeutically active cells using microfluidics
WO2019069900A1 (en) 2017-10-03 2019-04-11 Nok株式会社 Cell capturing device
CN107723207B (en) * 2017-11-01 2019-01-01 深圳市瑞格生物科技有限公司 A kind of chip of separating trap cell and its application in tumour cell sorting
US12011679B2 (en) * 2017-11-17 2024-06-18 International Business Machines Corporation Single layer nanofluidic separator chip and fluidic processor
JP7412688B2 (en) * 2018-03-08 2024-01-15 富山県 particle separator
US11230692B2 (en) 2018-03-27 2022-01-25 Hewlett-Packard Development Company, L.P. Particle separation and analysis
WO2019190488A1 (en) 2018-03-27 2019-10-03 Hewlett-Packard Development Company, L.P. Particle separation
US11185861B2 (en) 2018-06-13 2021-11-30 International Business Machines Corporation Multistage deterministic lateral displacement device for particle separation
DE102018210665A1 (en) 2018-06-29 2020-01-02 Robert Bosch Gmbh Microfluidic flow cell and method for separating cells
US20220127571A1 (en) * 2019-01-29 2022-04-28 Gpb Scientific, Inc. Cell populations with improved production and therapeutic characteristics
US11173486B2 (en) * 2019-02-13 2021-11-16 International Business Machines Corporation Fluidic cavities for on-chip layering and sealing of separation arrays
JP7714318B2 (en) * 2019-06-10 2025-07-29 Toppanホールディングス株式会社 Separation Device
WO2020250844A1 (en) * 2019-06-14 2020-12-17 凸版印刷株式会社 Method for separating cells
WO2020255753A1 (en) * 2019-06-21 2020-12-24 凸版印刷株式会社 Separation device and separation method
JP7482449B2 (en) * 2020-01-17 2024-05-14 富山県 Particle Separator
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US20240159632A1 (en) * 2021-03-16 2024-05-16 Sony Group Corporation Closed-system automated sample sorting system
WO2023189095A1 (en) 2022-03-28 2023-10-05 国立大学法人茨城大学 White blood cell capturing device
EP4608556A1 (en) * 2022-10-24 2025-09-03 National Resilience, Inc. Systems, methods, and compositions for selecting or isolating cells

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JP4297767B2 (en) * 2003-01-28 2009-07-15 テルモ株式会社 Blood processing filter system
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Also Published As

Publication number Publication date
EP3263693A1 (en) 2018-01-03
US20180038876A1 (en) 2018-02-08
JP2021007402A (en) 2021-01-28
WO2016136273A1 (en) 2016-09-01
CN107250343B (en) 2020-12-29
EP3263693A4 (en) 2018-02-21
US10996216B2 (en) 2021-05-04
JP2020072708A (en) 2020-05-14
JPWO2016136273A1 (en) 2017-12-07
CN107250343A (en) 2017-10-13

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