SG11201608054YA - Method for detecting multispecific antibody light chain mispairing - Google Patents
Method for detecting multispecific antibody light chain mispairingInfo
- Publication number
- SG11201608054YA SG11201608054YA SG11201608054YA SG11201608054YA SG11201608054YA SG 11201608054Y A SG11201608054Y A SG 11201608054YA SG 11201608054Y A SG11201608054Y A SG 11201608054YA SG 11201608054Y A SG11201608054Y A SG 11201608054YA SG 11201608054Y A SG11201608054Y A SG 11201608054YA
- Authority
- SG
- Singapore
- Prior art keywords
- detecting
- light chain
- antibody light
- multispecific antibody
- chain mispairing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
- G01N33/6857—Antibody fragments
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14163165 | 2014-04-02 | ||
| EP15155361 | 2015-02-17 | ||
| PCT/EP2015/057164 WO2015150446A1 (en) | 2014-04-02 | 2015-04-01 | Method for detecting multispecific antibody light chain mispairing |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201608054YA true SG11201608054YA (en) | 2016-10-28 |
Family
ID=52774264
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201608054YA SG11201608054YA (en) | 2014-04-02 | 2015-04-01 | Method for detecting multispecific antibody light chain mispairing |
| SG10202107077QA SG10202107077QA (en) | 2014-04-02 | 2015-04-01 | Method for detecting multispecific antibody light chain mispairing |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10202107077QA SG10202107077QA (en) | 2014-04-02 | 2015-04-01 | Method for detecting multispecific antibody light chain mispairing |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20170115304A1 (ko) |
| EP (2) | EP4570917A3 (ko) |
| JP (1) | JP6666262B2 (ko) |
| KR (1) | KR102376287B1 (ko) |
| CN (2) | CN113092788A (ko) |
| SG (2) | SG11201608054YA (ko) |
| WO (1) | WO2015150446A1 (ko) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2417156E (pt) | 2009-04-07 | 2015-04-29 | Roche Glycart Ag | Anticorpos trivalentes, biespecíficos |
| JP6721590B2 (ja) | 2014-12-03 | 2020-07-15 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 多重特異性抗体 |
| CA3097605A1 (en) * | 2018-04-17 | 2019-10-24 | Invenra Inc. | Trivalent trispecific antibody constructs |
| JP2022513708A (ja) * | 2018-12-05 | 2022-02-09 | モルフォシス・アーゲー | 多重特異性抗原結合分子 |
| EP4437344A1 (en) * | 2021-11-25 | 2024-10-02 | F. Hoffmann-La Roche AG | Quantification of low amounts of antibody sideproducts |
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| US5959177A (en) | 1989-10-27 | 1999-09-28 | The Scripps Research Institute | Transgenic plants expressing assembled secretory antibodies |
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| US5770429A (en) | 1990-08-29 | 1998-06-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
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| US6407213B1 (en) | 1991-06-14 | 2002-06-18 | Genentech, Inc. | Method for making humanized antibodies |
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| WO1993008829A1 (en) | 1991-11-04 | 1993-05-13 | The Regents Of The University Of California | Compositions that mediate killing of hiv-infected cells |
| US5747654A (en) | 1993-06-14 | 1998-05-05 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant disulfide-stabilized polypeptide fragments having binding specificity |
| US5789199A (en) | 1994-11-03 | 1998-08-04 | Genentech, Inc. | Process for bacterial production of polypeptides |
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| US6040498A (en) | 1998-08-11 | 2000-03-21 | North Caroline State University | Genetically engineered duckweed |
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| DK1034298T3 (da) | 1997-12-05 | 2012-01-30 | Scripps Research Inst | Humanisering af murint antistof |
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| KR100797667B1 (ko) | 1999-10-04 | 2008-01-23 | 메디카고 인코포레이티드 | 외래 유전자의 전사를 조절하는 방법 |
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| KR20240025059A (ko) | 2010-11-30 | 2024-02-26 | 추가이 세이야쿠 가부시키가이샤 | 세포상해 유도 치료제 |
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| CA2869529A1 (en) | 2012-05-24 | 2013-11-28 | Raffaella CASTOLDI | Multispecific antibodies |
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| US9914785B2 (en) | 2012-11-28 | 2018-03-13 | Zymeworks Inc. | Engineered immunoglobulin heavy chain-light chain pairs and uses thereof |
| WO2014121031A1 (en) * | 2013-01-31 | 2014-08-07 | Excelimmune, Inc. | Characterization of antibody mixtures by mass spectrometry |
-
2015
- 2015-04-01 KR KR1020167028373A patent/KR102376287B1/ko active Active
- 2015-04-01 EP EP24207684.2A patent/EP4570917A3/en active Pending
- 2015-04-01 CN CN202110521522.6A patent/CN113092788A/zh active Pending
- 2015-04-01 WO PCT/EP2015/057164 patent/WO2015150446A1/en active Application Filing
- 2015-04-01 SG SG11201608054YA patent/SG11201608054YA/en unknown
- 2015-04-01 JP JP2016560359A patent/JP6666262B2/ja active Active
- 2015-04-01 EP EP15712970.1A patent/EP3126389B1/en active Active
- 2015-04-01 SG SG10202107077QA patent/SG10202107077QA/en unknown
- 2015-04-01 CN CN201580018014.9A patent/CN106164288A/zh active Pending
-
2016
- 2016-09-28 US US15/278,242 patent/US20170115304A1/en not_active Abandoned
-
2019
- 2019-05-20 US US16/417,150 patent/US11486882B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20170115304A1 (en) | 2017-04-27 |
| EP4570917A3 (en) | 2025-09-03 |
| US11486882B2 (en) | 2022-11-01 |
| WO2015150446A1 (en) | 2015-10-08 |
| SG10202107077QA (en) | 2021-07-29 |
| KR20160140723A (ko) | 2016-12-07 |
| JP6666262B2 (ja) | 2020-03-13 |
| KR102376287B1 (ko) | 2022-03-17 |
| CN106164288A (zh) | 2016-11-23 |
| EP3126389A1 (en) | 2017-02-08 |
| EP4570917A2 (en) | 2025-06-18 |
| EP3126389B1 (en) | 2024-10-23 |
| JP2017509669A (ja) | 2017-04-06 |
| US20200103413A1 (en) | 2020-04-02 |
| CN113092788A (zh) | 2021-07-09 |
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