SA515360233B1 - Inhibitors of histone demethylases - Google Patents
Inhibitors of histone demethylasesInfo
- Publication number
- SA515360233B1 SA515360233B1 SA515360233A SA515360233A SA515360233B1 SA 515360233 B1 SA515360233 B1 SA 515360233B1 SA 515360233 A SA515360233 A SA 515360233A SA 515360233 A SA515360233 A SA 515360233A SA 515360233 B1 SA515360233 B1 SA 515360233B1
- Authority
- SA
- Saudi Arabia
- Prior art keywords
- compounds
- inhibitors
- histone demethylases
- present application
- discloses
- Prior art date
Links
- 102000008157 Histone Demethylases Human genes 0.000 title abstract 3
- 108010074870 Histone Demethylases Proteins 0.000 title abstract 3
- 239000003112 inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000008482 dysregulation Effects 0.000 abstract 1
- 230000008506 pathogenesis Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The present application discloses compounds capable of modulating the activity of histone demethylases (HDMEs), which are useful for prevention and/or treatment of diseases in which genomic dysregulation is involved in the pathogenesis, such as e.g. cancer. The present application also discloses pharmaceutical compositions comprising said compounds and the use of such compounds as a medicament. The compounds take the form (I). (I)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261708806P | 2012-10-02 | 2012-10-02 | |
| DKPA201200599 | 2012-10-02 | ||
| US201361770050P | 2013-02-27 | 2013-02-27 | |
| DKPA201370112 | 2013-02-27 | ||
| PCT/EP2013/070457 WO2014053491A1 (en) | 2012-10-02 | 2013-10-01 | Inhibitors of histone demethylases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SA515360233B1 true SA515360233B1 (en) | 2017-11-12 |
Family
ID=71451029
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SA515360233A SA515360233B1 (en) | 2012-10-02 | 2015-04-02 | Inhibitors of histone demethylases |
Country Status (2)
| Country | Link |
|---|---|
| EC (1) | ECSP15017165A (en) |
| SA (1) | SA515360233B1 (en) |
-
2015
- 2015-04-02 SA SA515360233A patent/SA515360233B1/en unknown
- 2015-04-30 EC ECIEPI201517165A patent/ECSP15017165A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ECSP15017165A (en) | 2016-01-29 |
| HK1247920A1 (en) | 2018-10-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PH12017501306A1 (en) | Inhibitors of histone demethylases | |
| ZA201606320B (en) | Human plasma kallikrein inhibitors | |
| MX2015008957A (en) | Fluoro-[1,3]oxazines as bace1 inhibitors. | |
| PH12015501868A1 (en) | Inhibitors of histone demethylases | |
| GEP201706624B (en) | Triazolopyrazine as brd4 inhibitors and usage thereof for cancer treatment | |
| NZ708382A (en) | Cycloalkyl bis-thiadiazole inhibitors of glutaminase and their use as therapeutic agents | |
| BR112014021531A2 (en) | compound, pharmaceutical composition and uses thereof | |
| GEP20156347B (en) | Benzodioxane inhibitors of leukotriene production | |
| UA110943C2 (en) | N-ACYLSULPHONAMIDE PROMOTERS OF APOPTOSIS | |
| EA201201192A1 (en) | THIENOPYRIMIDINES CONTAINING A SUBSTITUTE ALKYL GROUP INTENDED FOR PHARMACEUTICAL COMPOSITIONS | |
| HK1213888A1 (en) | Therapeutic compounds and compositions and their use as pkm2 modulators | |
| UA113538C2 (en) | FLUOROMETHYL-5,6-DIHYDRO-4H- $ 1,3] OXAZINES | |
| UA118610C2 (en) | Spirocyclic inhibitors of cathepsin c | |
| PH12015502365A1 (en) | Bace1 inhibitors | |
| PH12013500644A1 (en) | Co-crystals and salts of ccr3-inhibitors | |
| EA201690039A1 (en) | RORC2 INHIBITORS AND METHODS OF THEIR APPLICATION | |
| PH12014502623A1 (en) | Difluoro-hexahydro-cyclopentaoxazinyls and difluoro-hexahydro-benzooxazinyls as bace1 inhibitors | |
| EA201692481A1 (en) | COMBINATION CONTAINING GLUCOCORTICOID AND EDO-S101 | |
| NZ702254A (en) | 5-amino[1,4]thiazines as bace 1 inhibitors | |
| CL2017002229A1 (en) | Bace1 inhibitors. | |
| SA515360233B1 (en) | Inhibitors of histone demethylases | |
| EA201690673A1 (en) | COMBINED THERAPY LACHINIMODOMAT FOR THE TREATMENT OF MULTIPLE SCLEROSIS | |
| TN2013000150A1 (en) | Co-crystals and salts of ccr3-inhibitors | |
| EA202091668A3 (en) | HUMAN PLASMA CALLICREIN INHIBITORS |