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PT2910570T - Análogos de insulina acilados, estabilizados contra proteases - Google Patents

Análogos de insulina acilados, estabilizados contra proteases

Info

Publication number
PT2910570T
PT2910570T PT141985135T PT14198513T PT2910570T PT 2910570 T PT2910570 T PT 2910570T PT 141985135 T PT141985135 T PT 141985135T PT 14198513 T PT14198513 T PT 14198513T PT 2910570 T PT2910570 T PT 2910570T
Authority
PT
Portugal
Prior art keywords
insulin analogues
acylated insulin
protease stabilized
protease
stabilized
Prior art date
Application number
PT141985135T
Other languages
English (en)
Inventor
Hoeg-Jensen Thomas
Møller Tagmose Tina
Børglum Kjeldsen Thomas
Glendorf Tine
W Garibay Patrick
Madsen Peter
Jakobsen Palle
Tibor Kodra János
Sten Petersen Jacob
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of PT2910570T publication Critical patent/PT2910570T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
PT141985135T 2008-03-18 2009-03-13 Análogos de insulina acilados, estabilizados contra proteases PT2910570T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08102708 2008-03-18
EP08170231 2008-11-28

Publications (1)

Publication Number Publication Date
PT2910570T true PT2910570T (pt) 2017-01-24

Family

ID=40673840

Family Applications (2)

Application Number Title Priority Date Filing Date
PT141985135T PT2910570T (pt) 2008-03-18 2009-03-13 Análogos de insulina acilados, estabilizados contra proteases
PT97229348T PT2254906T (pt) 2008-03-18 2009-03-13 Análogos de insulina acilados, estabilizados contra proteases

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT97229348T PT2254906T (pt) 2008-03-18 2009-03-13 Análogos de insulina acilados, estabilizados contra proteases

Country Status (22)

Country Link
US (5) US8691759B2 (pt)
EP (4) EP2254906B1 (pt)
JP (4) JP5749155B2 (pt)
KR (3) KR20110004366A (pt)
CN (1) CN102037008B (pt)
AU (1) AU2009226910B2 (pt)
BR (1) BRPI0910348B1 (pt)
CA (1) CA2718738C (pt)
DK (2) DK2910570T3 (pt)
ES (2) ES2609288T3 (pt)
FI (1) FIC20240029I1 (pt)
FR (1) FR24C1037I1 (pt)
HU (3) HUE032287T2 (pt)
IL (3) IL207748A0 (pt)
MX (1) MX2010009850A (pt)
NL (1) NL301283I2 (pt)
NO (1) NO2024044I1 (pt)
PL (2) PL2910570T3 (pt)
PT (2) PT2910570T (pt)
RU (1) RU2571857C2 (pt)
WO (1) WO2009115469A1 (pt)
ZA (1) ZA201006126B (pt)

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CN103897053B (zh) * 2012-12-25 2019-01-15 深圳先进技术研究院 化学修饰的胸腺肽α1及其合成方法
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JP2016524617A (ja) * 2013-05-30 2016-08-18 ノヴォ ノルディスク アー/エス 糖尿病の治療のための新規な経口医薬組成物
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AU2014333979B2 (en) 2013-10-07 2018-02-15 Novo Nordisk A/S Novel derivative of an insulin analogue
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JO3624B1 (ar) 2014-05-08 2020-08-27 Lilly Co Eli تركيبات إنسولين سريعة المفعول
TW201630622A (zh) 2014-12-16 2016-09-01 美國禮來大藥廠 速效胰島素組合物
HRP20211281T1 (hr) 2016-12-16 2021-11-12 Novo Nordisk A/S Pripravci koji sadrže inzulin

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AU2009226910A1 (en) 2009-09-24
RU2010141481A (ru) 2012-04-27
IL250549B (en) 2018-12-31
US20190112348A1 (en) 2019-04-18
CN102037008B (zh) 2016-08-31
IL250549A0 (en) 2017-03-30
JP5749155B2 (ja) 2015-07-15
IL207748A0 (en) 2010-12-30
EP2910569A1 (en) 2015-08-26
HUE032287T2 (en) 2017-09-28
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CA2718738C (en) 2019-05-07
NO2024044I1 (no) 2024-10-08
JP2015155421A (ja) 2015-08-27
IL250548A0 (en) 2017-03-30
CN102037008A (zh) 2011-04-27
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US8691759B2 (en) 2014-04-08
EP2254906B1 (en) 2016-10-05
KR20160124929A (ko) 2016-10-28
KR20160073431A (ko) 2016-06-24
JP2011515358A (ja) 2011-05-19
US20140073564A1 (en) 2014-03-13
WO2009115469A1 (en) 2009-09-24
CA2718738A1 (en) 2009-09-24
KR101755434B1 (ko) 2017-07-10
ZA201006126B (en) 2011-11-30
DK2254906T3 (en) 2017-01-23
US9045560B2 (en) 2015-06-02
KR101755529B1 (ko) 2017-07-07
US20150210747A1 (en) 2015-07-30
BRPI0910348B1 (pt) 2021-06-29
FR24C1037I1 (fr) 2024-12-06
MX2010009850A (es) 2010-09-30
HUS2400029I1 (hu) 2024-08-28
US10259856B2 (en) 2019-04-16
EP2910571A1 (en) 2015-08-26
PT2254906T (pt) 2017-01-03
US20110105720A1 (en) 2011-05-05
US9688737B2 (en) 2017-06-27
PL2254906T3 (pl) 2017-04-28
EP2910571B1 (en) 2016-10-05
EP2254906A1 (en) 2010-12-01
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IL250548B (en) 2019-03-31

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