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PE20080142A1 - Beta-agonistas enantiomericamente puros y sus procedimientos de preparacion - Google Patents

Beta-agonistas enantiomericamente puros y sus procedimientos de preparacion

Info

Publication number
PE20080142A1
PE20080142A1 PE2007000271A PE2007000271A PE20080142A1 PE 20080142 A1 PE20080142 A1 PE 20080142A1 PE 2007000271 A PE2007000271 A PE 2007000271A PE 2007000271 A PE2007000271 A PE 2007000271A PE 20080142 A1 PE20080142 A1 PE 20080142A1
Authority
PE
Peru
Prior art keywords
enanthomerically
agonists
compounds
refers
preparation procedures
Prior art date
Application number
PE2007000271A
Other languages
English (en)
Inventor
Uwe Ries
Peter Sieger
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of PE20080142A1 publication Critical patent/PE20080142A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

SE REFIERE A COMPUESTOS DE FORMULA (1), EN DONDE n ES DE 1 A 4; X ES CH2, C0, NR2, S U O; B ES UN GRUPO DE ENLACE DOBLE: CR3R4-O; R1 ES H, ALQUILO(C1-C6),ALQUENILO(C2-C6), CICLOALQUILO, HALOGENO, OH, ENTRE OTROS; Ym- ES UN ANION CARGADO NEGATIVAMENTE m VECES, SIENDO ESTE ANION SELECIONADO DE CLORURO, YODURO, SULFATO, METANSULFONATO, ENTRE OTROS; m ES DE 1 O 2. SON PREFERIDAS LAS SALES MALEINATO, TARTRATO Y HEMI-ETANDISULFONATO DEL COMPUESTO 8-{2-[1,1-DIMETIL-3-(2-OXO-2,3-DIHIDRO-BENZOIMIDAZOL-1-IL)-PROPILAMINO]-1-HIDROXI-4H-BENZO[1,4]OXAZIN-3-ONA CRISTALINAS. TAMBIEN SE REFIERE A UN PROCEDIMIENTO DE PREPARACION Y UNA COMPOSICION FARMACEUTICA EN FORMA DE POLVOS PARA INHALACION Y AEROSOLES DE SUSPENSION. ESTOS COMPUESTOS SON BETAMIMETICOS UTILES EN EL TRATAMIENTO DE ENFERMEDADES DE LAS VIAS RESPIRATORIAS
PE2007000271A 2006-03-15 2007-03-13 Beta-agonistas enantiomericamente puros y sus procedimientos de preparacion PE20080142A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06111191 2006-03-15
EP06111342 2006-03-17
EP06111338 2006-03-17

Publications (1)

Publication Number Publication Date
PE20080142A1 true PE20080142A1 (es) 2008-04-14

Family

ID=38006901

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2007000271A PE20080142A1 (es) 2006-03-15 2007-03-13 Beta-agonistas enantiomericamente puros y sus procedimientos de preparacion

Country Status (16)

Country Link
US (2) US7534789B2 (es)
EP (1) EP1996581A1 (es)
JP (1) JP2009530245A (es)
KR (1) KR20080106973A (es)
AR (1) AR059836A1 (es)
AU (1) AU2007224420A1 (es)
BR (1) BRPI0709601A2 (es)
CA (1) CA2643026A1 (es)
EA (1) EA200801894A1 (es)
EC (1) ECSP088723A (es)
MX (1) MX2008011700A (es)
NO (1) NO20083508L (es)
PE (1) PE20080142A1 (es)
TW (1) TW200804360A (es)
UY (1) UY30207A1 (es)
WO (1) WO2007104772A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7799336B2 (en) 2004-04-30 2010-09-21 Allergan, Inc. Hypotensive lipid-containing biodegradable intraocular implants and related methods
PE20080142A1 (es) * 2006-03-15 2008-04-14 Boehringer Ingelheim Int Beta-agonistas enantiomericamente puros y sus procedimientos de preparacion
ES2805880T3 (es) 2013-10-31 2021-02-15 Allergan Inc Implantes intraoculares que contienen prostamida y métodos de uso de éstos

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2609645A1 (de) * 1976-03-09 1977-09-15 Boehringer Sohn Ingelheim Aminoalkylheterocyclen
DE10253282A1 (de) * 2002-11-15 2004-05-27 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittel zur Behandlung von chronisch obstruktiver Lungenerkrankung
US7056916B2 (en) 2002-11-15 2006-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments for the treatment of chronic obstructive pulmonary disease
DE102004003428A1 (de) 2004-01-23 2005-08-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue langwirksame Beta-2-Agonisten, und deren Verwendung als Arzneimittel
US7220742B2 (en) 2004-05-14 2007-05-22 Boehringer Ingelheim International Gmbh Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
DE102004024454A1 (de) * 2004-05-14 2005-12-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Enantiomerenreine Betaagonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
DE102004045648A1 (de) 2004-09-21 2006-03-23 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Betamimetika zur Behandlung von Atemwegserkrankungen
US20080176744A1 (en) 2005-03-10 2008-07-24 Basf Aktiengesellschaft Use of 4-Aminopyrimidines for Controlling Harmful Fungi, Novel 4-Aminopyrimidines, Processes for Their Preparation and Compositions Comprising Them
JP2009526817A (ja) * 2006-02-16 2009-07-23 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 呼吸器疾患の治療用医薬組成物
PE20080142A1 (es) 2006-03-15 2008-04-14 Boehringer Ingelheim Int Beta-agonistas enantiomericamente puros y sus procedimientos de preparacion

Also Published As

Publication number Publication date
WO2007104772A9 (de) 2007-11-22
ECSP088723A (es) 2008-10-31
KR20080106973A (ko) 2008-12-09
JP2009530245A (ja) 2009-08-27
EP1996581A1 (de) 2008-12-03
EA200801894A1 (ru) 2009-02-27
US7939658B2 (en) 2011-05-10
BRPI0709601A2 (pt) 2011-07-19
MX2008011700A (es) 2008-09-24
NO20083508L (no) 2008-09-30
AU2007224420A1 (en) 2007-09-20
US20070249595A1 (en) 2007-10-25
TW200804360A (en) 2008-01-16
US20090306068A1 (en) 2009-12-10
US7534789B2 (en) 2009-05-19
AR059836A1 (es) 2008-04-30
UY30207A1 (es) 2007-10-31
WO2007104772A1 (de) 2007-09-20
CA2643026A1 (en) 2007-09-20

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