PE20070698A1 - Comprimido de disgregacion rapida intraoral que contiene hidrocloruro de ambroxol - Google Patents
Comprimido de disgregacion rapida intraoral que contiene hidrocloruro de ambroxolInfo
- Publication number
- PE20070698A1 PE20070698A1 PE2006001419A PE2006001419A PE20070698A1 PE 20070698 A1 PE20070698 A1 PE 20070698A1 PE 2006001419 A PE2006001419 A PE 2006001419A PE 2006001419 A PE2006001419 A PE 2006001419A PE 20070698 A1 PE20070698 A1 PE 20070698A1
- Authority
- PE
- Peru
- Prior art keywords
- disgregation
- composition
- ambroxol hydrochloride
- amount
- tablet containing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/131—Amines acyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nutrition Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physiology (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SE REFIERE A UNA COMPOSICION FARMACEUTICA SOLIDA TAL COMO UN COMPRIMIDO DE DISGREGACION RAPIDA INTRAORAL QUE COMPRENDE: A) UN GRANULO QUE TIENE UN ESPACIO VACIO DENTRO DEL MISMO QUE CONTIENE i) UN DESINTEGRANTE TAL COMO CROSPOVIDONA EN UNA CANTIDAD DE 4% A 20% EN PESO DE LA COMPOSICION; ii) HIDROCLORURO DE AMBROXOL; iii) ERITRITOL O MANITOL; B) UN DESINTEGRANTE UTILIZADO COMO RECUBRIMIENTO DEL GRANULO TAL COMO CROSPOVIDONA EN UNA CANTIDAD DE 4% A 20% EN PESO DE LA COMPOSICION; C) UN LUBRICANTE TAL COMO ACIDO SILICICO ANHIDRO LIGERO O UNA SAL DE ESTEARATO. SE REFIERE TAMBIEN A UN PROCEDIMIENTO DE PREPARACION. DICHA COMPOSICION SE DESINTEGRA RAPIDAMENTE CON UNA BUENA SENSACION EN LA CAVIDAD ORAL
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005328722 | 2005-11-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20070698A1 true PE20070698A1 (es) | 2007-08-17 |
Family
ID=38023405
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2006001419A PE20070698A1 (es) | 2005-11-14 | 2006-11-13 | Comprimido de disgregacion rapida intraoral que contiene hidrocloruro de ambroxol |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10300021B2 (es) |
| EP (2) | EP1957051B1 (es) |
| JP (2) | JP4934144B2 (es) |
| KR (1) | KR101298379B1 (es) |
| CN (2) | CN103637996A (es) |
| AR (1) | AR057581A1 (es) |
| AU (1) | AU2006312566B2 (es) |
| CA (1) | CA2629487C (es) |
| ES (1) | ES2702757T3 (es) |
| PE (1) | PE20070698A1 (es) |
| TW (1) | TWI478732B (es) |
| WO (2) | WO2007055427A1 (es) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20070698A1 (es) | 2005-11-14 | 2007-08-17 | Teijin Pharma Ltd | Comprimido de disgregacion rapida intraoral que contiene hidrocloruro de ambroxol |
| CN101646461A (zh) * | 2007-03-13 | 2010-02-10 | 大日本住友制药株式会社 | 口腔崩解片 |
| GB2453770A (en) * | 2007-10-19 | 2009-04-22 | Reckitt Benckiser Healthcare | Oral composition comprising a cooling agent |
| JP5835875B2 (ja) * | 2009-06-29 | 2015-12-24 | 富士化学工業株式会社 | 口腔内速崩壊錠の製造方法 |
| EP2594269A4 (en) * | 2010-06-16 | 2013-12-04 | Teijin Pharma Ltd | CORE TABLET WITH CONTROLLED RELEASE |
| NZ605562A (en) | 2010-07-09 | 2013-11-29 | Teijin Pharma Ltd | Deuterated benzylbenzene derivatives and methods of use |
| US20130115287A1 (en) * | 2010-07-09 | 2013-05-09 | Teijin Pharma Limited | Intraorally disintegrating tablet |
| BR112013017600A2 (pt) * | 2011-01-17 | 2016-10-18 | Takeda Pharmaceutical | preparação para desintegração rápida, método para produzir uma preparação para desintegração rápida, preparação para absorção pela mucosa oral, método e droga para a profilaxia e / ou tratamento de um distúrbio bipolar, e, composto |
| WO2013001441A1 (en) * | 2011-06-29 | 2013-01-03 | Ranbaxy Laboratories Limited | Dry formulations of febuxostat |
| JP6823913B2 (ja) * | 2014-06-18 | 2021-02-03 | 大正製薬株式会社 | 固形製剤 |
| JP6073843B2 (ja) * | 2014-09-10 | 2017-02-01 | 佐藤製薬株式会社 | 硬度及び崩壊性に優れた口腔内崩壊錠の製造方法及び該製造方法により製造される口腔内崩壊錠 |
| EP3206671B1 (en) | 2014-10-16 | 2024-06-12 | Cargill, Incorporated | Process for preparing a directly compressible erythritol and uses thereof |
| JP6496085B2 (ja) * | 2016-06-16 | 2019-04-03 | 東和薬品株式会社 | 口腔内崩壊錠 |
| JP6606287B2 (ja) * | 2016-07-27 | 2019-11-13 | 沢井製薬株式会社 | 口腔内崩壊錠添加用組成物 |
| JP6201017B2 (ja) * | 2016-08-04 | 2017-09-20 | 佐藤製薬株式会社 | 硬度及び崩壊性に優れた口腔内崩壊錠の製造方法及び該製造方法により製造される口腔内崩壊錠 |
| TWI650142B (zh) * | 2016-09-06 | 2019-02-11 | 日商澤井製藥股份有限公司 | 口腔内崩解錠添加用組成物 |
| WO2021099935A1 (en) * | 2019-11-18 | 2021-05-27 | Zycie Technolegal Llp | Pharmaceutical formulations for managing uric acid content in human body |
| JP7486258B2 (ja) * | 2019-12-26 | 2024-05-17 | 物産フードサイエンス株式会社 | 口腔内崩壊錠用顆粒、その製造方法および口腔内崩壊錠 |
| JP7195660B1 (ja) | 2021-09-09 | 2022-12-26 | 壽製薬株式会社 | 口腔内崩壊錠 |
| US20230420715A1 (en) | 2021-12-09 | 2023-12-28 | Bloom Energy Corporation | Fuel cell system and method of operating thereof at near one hundred percent fuel utilization |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US215500A (en) * | 1879-05-20 | Improvement in distance-instruments | ||
| US49315A (en) * | 1865-08-08 | Improvement in photographic cameras | ||
| US134199A (en) * | 1872-12-24 | Improvement in car-couplings | ||
| US98227A (en) * | 1869-12-28 | Improved railway-car | ||
| US112196A (en) * | 1871-02-28 | Improvement in horse-collars | ||
| US4684516A (en) * | 1983-08-01 | 1987-08-04 | Alra Laboratories, Inc. | Sustained release tablets and method of making same |
| DE69331839T2 (de) | 1992-01-29 | 2002-12-12 | Takeda Chemical Industries, Ltd. | Schnellösliche Tablette und ihre Herstellung |
| US8071128B2 (en) | 1996-06-14 | 2011-12-06 | Kyowa Hakko Kirin Co., Ltd. | Intrabuccally rapidly disintegrating tablet and a production method of the tablets |
| DE69738829D1 (de) * | 1996-07-12 | 2008-08-21 | Daiichi Seiyaku Co | Schnell zerfallende, druckgeformte Materialien sowie Prozess zu deren Herstellung |
| AR016827A1 (es) | 1997-08-22 | 2001-08-01 | Smithkline Beecham Corp | PROCEDIMIENTO PARA LA PREPARACIoN DE UNA TABLETA FARMACÉUTICA |
| JP3786578B2 (ja) | 1997-11-18 | 2006-06-14 | 帝人ファーマ株式会社 | 環状アミン誘導体、およびその薬剤としての使用法 |
| PL340658A1 (en) | 1997-11-20 | 2001-02-12 | Teijin Ltd | Derivatives of biphenylamidine |
| ES2235500T3 (es) * | 1998-07-24 | 2005-07-01 | Franz Haas Waffel-Und Keksanlagen-Industrie Gmbh | Uso de eritritol y/o xilitol en masas para hornear o masas pasa productos de panaderis y pasteleria de larga duracion compuestos por harinas y/o almidones como sustitutos parciales o totales del azucar. |
| ATE481090T1 (de) | 1998-07-28 | 2010-10-15 | Takeda Pharmaceutical | Leicht zerfallende feste zubereitung |
| FR2795962B1 (fr) | 1999-07-08 | 2003-05-09 | Prographarm Laboratoires | Procede de fabrication de granules enrobes a gout masque et liberation immediate du principe actif |
| AU777813B2 (en) | 2000-01-17 | 2004-11-04 | Teijin Limited | Benzimidazole derivatives |
| KR100784659B1 (ko) | 2000-06-30 | 2007-12-12 | 아스텔라스세이야쿠 가부시키가이샤 | 구강내 속붕괴정 |
| UA80393C2 (uk) * | 2000-12-07 | 2007-09-25 | Алтана Фарма Аг | Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці |
| JP4358117B2 (ja) | 2001-03-06 | 2009-11-04 | 協和発酵キリン株式会社 | 口腔内速崩壊錠 |
| WO2002069933A1 (fr) * | 2001-03-06 | 2002-09-12 | Kyowa Hakko Kogyo Co., Ltd. | Comprimés à délitement rapide dans la bouche |
| FR2823668B1 (fr) * | 2001-04-20 | 2004-02-27 | Ethypharm Lab Prod Ethiques | Comprimes effervescents orodispersibles |
| DE602004024960D1 (de) | 2003-01-21 | 2010-02-25 | Nippon Shinyaku Co Ltd | Rasch in der mundhöhle schmelzende tablette |
| SI21403A (sl) * | 2003-02-27 | 2004-08-31 | LEK farmacevtska dru�ba d.d. | Farmacevtska oblika z alendronsko kislino, njenimi solmi ali estri ter postopek za njeno pripravo |
| RU2375048C2 (ru) * | 2003-07-17 | 2009-12-10 | Д-Р Редди'С Лабораторис Инк. | Фармацевтическая композиция с набухающим покрытием |
| US20050112196A1 (en) | 2003-10-07 | 2005-05-26 | Jianbo Xie | Rapidly disintegrating formulation |
| JP4592272B2 (ja) | 2003-10-08 | 2010-12-01 | シャープ株式会社 | 給紙カセットおよび給紙装置 |
| US9884014B2 (en) * | 2004-10-12 | 2018-02-06 | Adare Pharmaceuticals, Inc. | Taste-masked pharmaceutical compositions |
| JP5123517B2 (ja) | 2005-11-14 | 2013-01-23 | 帝人ファーマ株式会社 | アンブロキソール口腔内速崩性錠剤 |
| PE20070698A1 (es) | 2005-11-14 | 2007-08-17 | Teijin Pharma Ltd | Comprimido de disgregacion rapida intraoral que contiene hidrocloruro de ambroxol |
| WO2008122993A1 (en) | 2007-04-09 | 2008-10-16 | Panacea Biotec Limited | Controlled release formulation of coated microparticles |
-
2006
- 2006-11-13 PE PE2006001419A patent/PE20070698A1/es not_active Application Discontinuation
- 2006-11-14 KR KR1020087014401A patent/KR101298379B1/ko not_active Expired - Fee Related
- 2006-11-14 EP EP06823462.4A patent/EP1957051B1/en not_active Not-in-force
- 2006-11-14 AR ARP060104991A patent/AR057581A1/es unknown
- 2006-11-14 US US12/092,852 patent/US10300021B2/en not_active Expired - Fee Related
- 2006-11-14 ES ES06823462T patent/ES2702757T3/es active Active
- 2006-11-14 WO PCT/JP2006/323061 patent/WO2007055427A1/en active Application Filing
- 2006-11-14 EP EP06823463A patent/EP1951203A4/en not_active Withdrawn
- 2006-11-14 CA CA2629487A patent/CA2629487C/en not_active Expired - Fee Related
- 2006-11-14 AU AU2006312566A patent/AU2006312566B2/en not_active Ceased
- 2006-11-14 TW TW095142089A patent/TWI478732B/zh not_active IP Right Cessation
- 2006-11-14 CN CN201310682491.8A patent/CN103637996A/zh active Pending
- 2006-11-14 WO PCT/JP2006/323062 patent/WO2007055428A1/en active Application Filing
- 2006-11-14 JP JP2008539669A patent/JP4934144B2/ja not_active Expired - Fee Related
- 2006-11-14 CN CN200680042409.3A patent/CN101309672B/zh not_active Expired - Fee Related
-
2009
- 2009-09-18 US US12/562,674 patent/US9511029B2/en not_active Expired - Fee Related
-
2011
- 2011-08-10 JP JP2011175017A patent/JP2011225624A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US9511029B2 (en) | 2016-12-06 |
| AU2006312566A1 (en) | 2007-05-18 |
| AU2006312566B2 (en) | 2012-04-12 |
| EP1951203A4 (en) | 2011-07-06 |
| KR20080073335A (ko) | 2008-08-08 |
| EP1957051A4 (en) | 2011-07-06 |
| JP4934144B2 (ja) | 2012-05-16 |
| US20100009004A1 (en) | 2010-01-14 |
| WO2007055427A1 (en) | 2007-05-18 |
| CA2629487C (en) | 2014-11-18 |
| CA2629487A1 (en) | 2007-05-18 |
| TWI478732B (zh) | 2015-04-01 |
| WO2007055428A1 (en) | 2007-05-18 |
| ES2702757T3 (es) | 2019-03-05 |
| CN101309672A (zh) | 2008-11-19 |
| EP1957051A1 (en) | 2008-08-20 |
| US20090117182A1 (en) | 2009-05-07 |
| EP1957051B1 (en) | 2018-11-14 |
| JP2009515871A (ja) | 2009-04-16 |
| AR057581A1 (es) | 2007-12-05 |
| US10300021B2 (en) | 2019-05-28 |
| JP2011225624A (ja) | 2011-11-10 |
| CN101309672B (zh) | 2015-07-29 |
| CN103637996A (zh) | 2014-03-19 |
| TW200738282A (en) | 2007-10-16 |
| EP1951203A1 (en) | 2008-08-06 |
| KR101298379B1 (ko) | 2013-08-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FX | Voluntary withdrawal |