PE20060484A1 - Preparaciones farmaceuticas liquidas que comprenden un compuesto de benzhidril piperizina - Google Patents
Preparaciones farmaceuticas liquidas que comprenden un compuesto de benzhidril piperizinaInfo
- Publication number
- PE20060484A1 PE20060484A1 PE2005000777A PE2005000777A PE20060484A1 PE 20060484 A1 PE20060484 A1 PE 20060484A1 PE 2005000777 A PE2005000777 A PE 2005000777A PE 2005000777 A PE2005000777 A PE 2005000777A PE 20060484 A1 PE20060484 A1 PE 20060484A1
- Authority
- PE
- Peru
- Prior art keywords
- benzhydril
- liquid pharmaceutical
- pharmaceutical preparations
- preparations containing
- par
- Prior art date
Links
- 239000007788 liquid Substances 0.000 title abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 2
- -1 BENZHYDRIL PIPERIZINE COMPOUND Chemical class 0.000 title 1
- 238000002360 preparation method Methods 0.000 abstract 2
- 239000003755 preservative agent Substances 0.000 abstract 2
- 230000002335 preservative effect Effects 0.000 abstract 2
- ZKLPARSLTMPFCP-OAQYLSRUSA-N 2-[2-[4-[(R)-(4-chlorophenyl)-phenylmethyl]-1-piperazinyl]ethoxy]acetic acid Chemical compound C1CN(CCOCC(=O)O)CCN1[C@@H](C=1C=CC(Cl)=CC=1)C1=CC=CC=C1 ZKLPARSLTMPFCP-OAQYLSRUSA-N 0.000 abstract 1
- ZKLPARSLTMPFCP-UHFFFAOYSA-N Cetirizine Chemical compound C1CN(CCOCC(=O)O)CCN1C(C=1C=CC(Cl)=CC=1)C1=CC=CC=C1 ZKLPARSLTMPFCP-UHFFFAOYSA-N 0.000 abstract 1
- OCBFFGCSTGGPSQ-UHFFFAOYSA-N [CH2]CC Chemical class [CH2]CC OCBFFGCSTGGPSQ-UHFFFAOYSA-N 0.000 abstract 1
- 229960001803 cetirizine Drugs 0.000 abstract 1
- 229960002152 chlorhexidine acetate Drugs 0.000 abstract 1
- ZZVUWRFHKOJYTH-UHFFFAOYSA-N diphenhydramine Chemical compound C=1C=CC=CC=1C(OCCN(C)C)C1=CC=CC=C1 ZZVUWRFHKOJYTH-UHFFFAOYSA-N 0.000 abstract 1
- 239000003221 ear drop Substances 0.000 abstract 1
- 229940047652 ear drops Drugs 0.000 abstract 1
- 125000001495 ethyl group Chemical class [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 239000003889 eye drop Substances 0.000 abstract 1
- 229940012356 eye drops Drugs 0.000 abstract 1
- 229960001508 levocetirizine Drugs 0.000 abstract 1
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical class [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000007923 nasal drop Substances 0.000 abstract 1
- 229940100662 nasal drops Drugs 0.000 abstract 1
- MCSINKKTEDDPNK-UHFFFAOYSA-N propyl propionate Chemical compound CCCOC(=O)CC MCSINKKTEDDPNK-UHFFFAOYSA-N 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 abstract 1
- 229940033663 thimerosal Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Otolaryngology (AREA)
- Ophthalmology & Optometry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
SE REFIERE A UNA PREPARACION FARMACEUTICA LIQUIDA CONFORMADA POR UN PRINCIPIO ACTIVO DEL GRUPO DE LAS BENZHIDRIL PIPERIZINAS, TAL COMO CETIRIZINA, LEVOCETIRIZINA Y EFLETIRIZINA Y AL MENOS UN CONSERVANTE TAL COMO LOS ESTERES DE PARAHIDROXIBENZOATO EN UNA CANTIDAD SUPERIOR A 0, E INFERIOR A 1,5 MG/ML DE LA PREPARACION, SIENDO PREFERIDOS PARAHIDROXIBENZOATO DE METILO, DE PROPILO, DE ETILO, O UNA MEZCLA DE ESTOS, EN UNA RELACION DE 9/1 EXPRESADA EN PESO; EN EL CASO DE LA UTILIZACION DE OTROS CONSERVANTES, ESTOS DEBEN PRODUCIR LOS MISMOS EFECTOS CONSERVANTES QUE LOS ESTERES DE PARAHIDROXIBENZOATO, EN LAS CONCENTRACIONES INDICADAS; SIENDO PREFERIDOS: TIMEROSAL, ACETATO DE CLORHEXIDINA, ALCOHOLBENCILICO, CLURORO DE BENZALCONIO, ENTRE OTROS. ESTAS PREPARACIONES SE PRESENTAN EN FORMA DE SOLUCIONES ORALES, GOTAS NASALES, OCULARES O GOTAS PARA OIDOS
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04016519 | 2004-07-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20060484A1 true PE20060484A1 (es) | 2006-07-06 |
Family
ID=34925743
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2005000777A PE20060484A1 (es) | 2004-07-14 | 2005-07-04 | Preparaciones farmaceuticas liquidas que comprenden un compuesto de benzhidril piperizina |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US8633194B2 (es) |
| EP (1) | EP1768649B1 (es) |
| JP (1) | JP4902875B2 (es) |
| KR (1) | KR101185612B1 (es) |
| CN (1) | CN100508981C (es) |
| AR (1) | AR049846A1 (es) |
| AT (1) | ATE443512T1 (es) |
| AU (1) | AU2005261953B2 (es) |
| BR (1) | BRPI0513257C1 (es) |
| CA (1) | CA2573662A1 (es) |
| CY (1) | CY1109670T1 (es) |
| DE (1) | DE602005016802D1 (es) |
| EA (1) | EA012463B1 (es) |
| ES (1) | ES2332462T3 (es) |
| HK (1) | HK1103958A1 (es) |
| IL (1) | IL180010A0 (es) |
| MX (1) | MX2007000230A (es) |
| MY (1) | MY149403A (es) |
| NO (1) | NO337768B1 (es) |
| NZ (1) | NZ552182A (es) |
| PE (1) | PE20060484A1 (es) |
| PL (1) | PL1768649T3 (es) |
| PT (1) | PT1768649E (es) |
| TW (1) | TWI304339B (es) |
| WO (1) | WO2006005507A2 (es) |
| ZA (1) | ZA200700939B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8569273B2 (en) | 2009-03-17 | 2013-10-29 | Aciex Therapeutics, Inc. | Ophthalmic formulations of cetirizine and methods of use |
| PT2408453T (pt) | 2009-03-17 | 2022-04-05 | Nicox Ophthalmics Inc | Formulações oftálmicas de cetirizina e métodos de utilização |
| TWI503122B (zh) * | 2012-02-15 | 2015-10-11 | Taiho Pharmaceutical Co Ltd | Oral administration of pharmaceutical compositions |
| KR102155836B1 (ko) | 2013-02-22 | 2020-09-14 | 삼성전자주식회사 | 터치 스크린 상에서 객체 디스플레이를 제어하는 휴대 단말 및 방법 |
| WO2018147409A1 (ja) * | 2017-02-13 | 2018-08-16 | 日東メディック株式会社 | 水性点眼点鼻用組成物 |
| CN113712907A (zh) * | 2020-05-25 | 2021-11-30 | 南京帝昌医药科技有限公司 | 一种盐酸左西替利嗪滴眼液组合物及其制备方法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4255358A (en) * | 1978-03-13 | 1981-03-10 | The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland | Process for the production of hexanitrostilbene |
| NO155805C (no) | 1981-02-06 | 1987-06-10 | Ucb Sa | Analogifremgangsmaate for fremstilling av terapeutisk virksomme 2-(4-(difenylmethyl)-1-piperazinyl)-eddiksyrer og deres amider og ikke-toksiske salter. |
| NZ215069A (en) * | 1985-03-01 | 1988-06-30 | Reckitt & Colmann Prod Ltd | Pharmaceutical composition with histamine h 2 -receptor antagonist |
| US4728509A (en) * | 1985-08-19 | 1988-03-01 | Takeda Chemical Industries, Ltd. | Aqueous liquid preparation |
| JP3278192B2 (ja) * | 1992-04-03 | 2002-04-30 | ロート製薬株式会社 | 徐放性液剤 |
| TW401300B (en) * | 1992-12-25 | 2000-08-11 | Senju Pharma Co | Antiallergic composition for ophthalmic or nasal use |
| US5504113A (en) * | 1994-03-02 | 1996-04-02 | Allergan, Inc. | Enhancement of benzalkonium chloride preservative activity in formulations containing an incompatible drug |
| EP0785780A1 (en) * | 1994-10-10 | 1997-07-30 | Novartis AG | Ophthalmic and aural compositions containing diclofenac potassium |
| TW536403B (en) * | 1997-03-24 | 2003-06-11 | Glaxo Group Ltd | An ethanol and ethylenediaminetetraacetic acid free pharmaceutical composition comprising lamivudine and exhibiting antimicrobial preservative efficacy |
| US6432961B1 (en) * | 1998-08-18 | 2002-08-13 | Ucb S.A. | Method for preventing the onset of asthma |
| AUPQ419099A0 (en) * | 1999-11-23 | 1999-12-16 | Ko, Thomas Sai Ying | Novel compositions and methods |
| DE10007203A1 (de) * | 2000-02-17 | 2001-08-23 | Asta Medica Ag | Neue Kombination nichtsedierender Antihistaminika mit Substanzen, die die Leukotrienwirkung beeinflussen, zur Behandlung der Rhinitis/Konjunktivitis |
| US6258814B1 (en) * | 2000-10-13 | 2001-07-10 | Schering Corporation | Method of using cetirizine and pharmaceutical compositions containing the same for inducing sleep |
| UA80393C2 (uk) * | 2000-12-07 | 2007-09-25 | Алтана Фарма Аг | Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці |
| AU2002221854A1 (en) | 2000-12-15 | 2002-06-24 | U C B, S.A. | Use of cetirizine or efletirizine for preventing urticaria |
| US6869618B2 (en) * | 2001-04-10 | 2005-03-22 | Kiel Laboratories, Inc. | Process for preparing tannate liquid and semi-solid dosage forms |
| MXPA04012393A (es) * | 2002-06-12 | 2005-06-17 | Chemocentryx | Derivados de piperazina 1-aril-4-substituidos para utilizar como antagonistas ccr1 para tratamiento de inflamacion y desordenes inmunes. |
| AU2003251152A1 (en) | 2002-07-03 | 2004-01-23 | Shannon Biotechnology Ltd | Pharmaceutical formulations for preparing drink products |
| MXPA05005795A (es) | 2002-12-03 | 2005-08-16 | Ucb Farchim Sa | Uso de levocetiricina para el tratamiento de la rinitis alergica persistente. |
| US20050255154A1 (en) | 2004-05-11 | 2005-11-17 | Lena Pereswetoff-Morath | Method and composition for treating rhinitis |
| US20090137645A1 (en) * | 2007-10-31 | 2009-05-28 | Midlothian Laboratories, Llc | Shelf-Stable Famotidine Granulates for Oral Suspensions |
-
2005
- 2005-07-04 PE PE2005000777A patent/PE20060484A1/es not_active Application Discontinuation
- 2005-07-06 US US10/599,451 patent/US8633194B2/en active Active
- 2005-07-06 TW TW094122831A patent/TWI304339B/zh not_active IP Right Cessation
- 2005-07-07 EA EA200700067A patent/EA012463B1/ru not_active IP Right Cessation
- 2005-07-07 PL PL05758582T patent/PL1768649T3/pl unknown
- 2005-07-07 BR BRPI0513257A patent/BRPI0513257C1/pt active IP Right Grant
- 2005-07-07 ZA ZA200700939A patent/ZA200700939B/xx unknown
- 2005-07-07 ES ES05758582T patent/ES2332462T3/es active Active
- 2005-07-07 WO PCT/EP2005/007340 patent/WO2006005507A2/en active Application Filing
- 2005-07-07 CN CNB2005800234732A patent/CN100508981C/zh not_active Ceased
- 2005-07-07 MY MYPI20053111A patent/MY149403A/en unknown
- 2005-07-07 AT AT05758582T patent/ATE443512T1/de active
- 2005-07-07 MX MX2007000230A patent/MX2007000230A/es active IP Right Grant
- 2005-07-07 DE DE602005016802T patent/DE602005016802D1/de active Active
- 2005-07-07 EP EP05758582A patent/EP1768649B1/en not_active Revoked
- 2005-07-07 CA CA002573662A patent/CA2573662A1/en not_active Abandoned
- 2005-07-07 KR KR1020077003545A patent/KR101185612B1/ko active Active
- 2005-07-07 NZ NZ552182A patent/NZ552182A/en not_active IP Right Cessation
- 2005-07-07 PT PT05758582T patent/PT1768649E/pt unknown
- 2005-07-07 JP JP2007520716A patent/JP4902875B2/ja active Active
- 2005-07-07 AU AU2005261953A patent/AU2005261953B2/en active Active
- 2005-07-13 AR ARP050102897A patent/AR049846A1/es not_active Application Discontinuation
-
2006
- 2006-12-12 IL IL180010A patent/IL180010A0/en unknown
-
2007
- 2007-02-13 NO NO20070832A patent/NO337768B1/no unknown
- 2007-07-27 HK HK07108213.7A patent/HK1103958A1/xx unknown
-
2009
- 2009-11-25 CY CY20091101233T patent/CY1109670T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |