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PE20030316A1 - Sistema de suministro de dos o mas agentes terapeuticamente activos - Google Patents

Sistema de suministro de dos o mas agentes terapeuticamente activos

Info

Publication number
PE20030316A1
PE20030316A1 PE2002000827A PE2002000827A PE20030316A1 PE 20030316 A1 PE20030316 A1 PE 20030316A1 PE 2002000827 A PE2002000827 A PE 2002000827A PE 2002000827 A PE2002000827 A PE 2002000827A PE 20030316 A1 PE20030316 A1 PE 20030316A1
Authority
PE
Peru
Prior art keywords
active agents
therapeutically active
delivery system
poly
same
Prior art date
Application number
PE2002000827A
Other languages
English (en)
Inventor
Juha Ala-Sorvari
Timo Haapakumpu
Antti Keinanen
Manja Ahola
Marko Aaltonen
Original Assignee
Leiras Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leiras Oy filed Critical Leiras Oy
Publication of PE20030316A1 publication Critical patent/PE20030316A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0039—Devices retained in the uterus for a prolonged period, e.g. intrauterine devices for contraception
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

QUE COMPRENDE: 1)UN NUCLEO QUE COMPRENDE AL MENOS DOS AGENTES TERAPEUTICAMENTE ACTIVOS, CADA UNO DE LOS CUALES TIENE UNA VELOCIDAD DE LIBERACION; 2)UNA MEMBRANA QUE ENCAPSULA A (1) QUE TIENE AL MENOS DOS CAPAS DE GROSOR DIFERENTE. CONSISTIENDO AMB0S (1) Y (2) DE UNA COMPOSICION DE ELASTOMERO IGUAL O DIFERENTE, SELECCIONADA DE: a)POLI(DIMETILSILOXANO); b)UN ELASTOMERO CON BASE DE SILOXANO QUE COMPRENDE GRUPOS 3,3,3-TRIFLUOROPROPILO UNIDOS A LOS ATOMOS DE Si DE LAS UNIDADES DE SILOXANO; c)GRUPOS POLI(OXIDO DE ALQUILENO) PRESENTES COMO INJERTOS TERMINADOS CON ALCOXI O BLOQUES UNIDOS A LAS UNIDADES DE POLISILOXANO MEDIANTE ENLACES DE SILICIO-CARBONO, O COMO UNA MEZCLA DE ESTAS FORMAS; Y d)UNA COMBINACION DE AL MENOS DOS DE LOS MISMOS. TIENE APLICACION COMO IMPLANTE, SISTEMA INTRAUTERINO, SISTEMA INTRACERVICAL, ENTRE OTROS
PE2002000827A 2001-08-31 2002-08-28 Sistema de suministro de dos o mas agentes terapeuticamente activos PE20030316A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31597201P 2001-08-31 2001-08-31

Publications (1)

Publication Number Publication Date
PE20030316A1 true PE20030316A1 (es) 2003-04-03

Family

ID=23226904

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2002000827A PE20030316A1 (es) 2001-08-31 2002-08-28 Sistema de suministro de dos o mas agentes terapeuticamente activos

Country Status (14)

Country Link
US (1) US20040247674A1 (es)
EP (1) EP1427390A1 (es)
JP (1) JP2005503389A (es)
KR (1) KR20040036928A (es)
CN (1) CN1289064C (es)
AR (1) AR036310A1 (es)
AU (1) AU2002313517B2 (es)
CA (1) CA2457979A1 (es)
HU (1) HUP0401438A3 (es)
NO (1) NO20041315L (es)
PE (1) PE20030316A1 (es)
PL (1) PL367961A1 (es)
RU (1) RU2302883C2 (es)
WO (1) WO2003017971A1 (es)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7005138B2 (en) * 2001-12-21 2006-02-28 Duramed Pharmaceuticals, Inc. Method of systematically delivering SSRIs
US20040181943A1 (en) * 2003-03-18 2004-09-23 Michael Kwiecien Shaving systems
TWI336627B (en) * 2003-05-23 2011-02-01 Organon Nv Drug delivery system,and use and manufacturing method thereof
CN1826100B (zh) * 2003-07-17 2010-12-22 旗帜药物胶囊公司 控释制剂
EP1508343B1 (en) * 2003-08-21 2015-11-04 AddBIO AB Bisphosponate coated implant device and method therefor
AU2005258225A1 (en) * 2004-06-22 2006-01-05 Greystone Medical Group, Inc. Methods for treatment of wounds using time release compositions
PL1629844T5 (pl) 2004-07-13 2012-10-31 Bayer Schering Pharma Oy Długoterminowy system dostarczania leku z kontrolowanym początkowym wyrzutem
US7494665B1 (en) * 2004-07-30 2009-02-24 Advanced Cardiovascular Systems, Inc. Polymers containing siloxane monomers
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
CN101448452B (zh) * 2006-03-20 2012-07-18 特卫华妇女健康有限公司 挠性压缩的阴道内环、其制备和使用方法及其生产设备
US8828981B2 (en) 2007-02-06 2014-09-09 George Creasy Progesterone for the treatment or prevention of spontaneous preterm birth
RU2342125C1 (ru) * 2007-04-27 2008-12-27 Александр Сергеевич Бабиков Способ введения анестетика в ткани
US8741329B2 (en) 2007-09-21 2014-06-03 Merck Sharp & Dohme B.V. Drug delivery system
EP2057972A1 (en) * 2007-11-07 2009-05-13 N.V. Organon Intrauterine deposit
TW200927141A (en) * 2007-11-22 2009-07-01 Bayer Schering Pharma Oy Vaginal delivery system
EP2062569B1 (en) * 2007-11-22 2011-05-11 Bayer Oy Vaginal delivery system
EP2062568A1 (en) * 2007-11-22 2009-05-27 Bayer Schering Pharma Oy Vaginal delivery system
US9314524B2 (en) * 2007-12-31 2016-04-19 Calla Therapeutics Llc Topical formulations of Flucytosine
DE102008006416A1 (de) * 2008-01-28 2009-07-30 Mayer, Thomas, Dr. med. Clindamycin zur Verwendung bei der Behandlung oder Vorbeugung der bakteriellen Vaginosis
ES2648640T3 (es) * 2008-02-04 2018-01-04 Ferring B.V. Anillos intravaginales monolíticos que comprenden progesterona y métodos de fabricación y usos de los mismos
EP2140860A1 (en) * 2008-07-03 2010-01-06 Bayer Schering Pharma Oy An improved method of contraception
FI20080524A0 (fi) 2008-09-17 2008-09-17 Bayer Schering Pharma Oy Insertteri
FI20080523A0 (fi) 2008-09-17 2008-09-17 Bayer Schering Pharma Oy Insertteri
US20110166508A1 (en) 2008-09-17 2011-07-07 Lyytikaeinen Heikki inserter
US11992431B2 (en) 2008-09-17 2024-05-28 Bayer Oy Inserter
DK2381932T3 (en) * 2009-01-29 2018-11-19 Fondazione Irccs Istituto Naz Dei Tumori INTRACERVIC DEVICE FOR THE RELEASE OF PHARMACEUTICALS IN THE LOCAL-REGIONAL TREATMENT OF CANCER CANCER
FI20095550A0 (fi) * 2009-05-19 2009-05-19 Bayer Schering Pharma Oy Vaginaalinen antojärjestelmä
FI122579B (fi) 2010-10-29 2012-03-30 Bayer Oy Insertteri
CN102525722A (zh) * 2010-12-30 2012-07-04 辽宁爱母医疗科技有限公司 具有记忆效应的智能型复方孕二烯酮阴道环制剂及其应用
EP2476409A1 (en) * 2011-01-14 2012-07-18 Université Catholique De Louvain Implant comprising a core and a tube encasing the core
DE202012012761U1 (de) * 2011-04-07 2013-10-29 Arstat, Inc. Mit Arzneimittel versehene intravaginale Vorrichtung und pharmazeutische Zusammensetzung zur Behandlung von Menstruationsschmerzen und übermäßigem Menstruationsblutverlust
US10028858B2 (en) 2011-07-11 2018-07-24 Medicines360 Intrauterine systems, IUD insertion devices, and related methods and kits therefor
EP2607451B8 (de) 2011-12-20 2019-03-27 Merck Patent GmbH Flüssigkristallines Medium
AR089765A1 (es) 2012-01-23 2014-09-17 Bayer Oy Un sistema para el suministro de un farmaco
USD718435S1 (en) 2012-05-30 2014-11-25 Medicines360 Intrauterine insertion device
US10154856B2 (en) 2013-02-06 2018-12-18 Mark SILLENDER Therapeutic substance transfer catheter and method
US10188426B2 (en) 2013-02-06 2019-01-29 Mark SILLENDER Embryo transfer catheter and method
SE539540C2 (sv) * 2013-09-12 2017-10-10 Qpharma Ab Ett läkemedelsavgivningssystem för en eller flera aktiva beståndsdelar
US9963556B2 (en) 2013-09-18 2018-05-08 Senseonics, Incorporated Critical point drying of hydrogels in analyte sensors
AU2014336286A1 (en) * 2013-10-18 2016-03-24 Bayer Oy Intrauterine delivery system
WO2015086489A1 (en) 2013-12-11 2015-06-18 Merck Sharp & Dohme B.V. Drug delivery system for delivery of anti-virals
US10413504B2 (en) 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system
US10772842B2 (en) * 2015-01-09 2020-09-15 Patheon Softgels Inc. Abuse-deterrent opioids
SG11201608483PA (en) * 2014-05-30 2016-11-29 Textile Based Delivery Inc Drug delivery systems and related methods of use
LT3247327T (lt) 2015-01-21 2019-10-10 Bayer Oy Vaisto pateikimo sistema, apimanti nesteroidinį priešuždegiminį (nsaid) ir progestogeninį junginį, ir gamybos būdai
JP6898856B2 (ja) * 2015-05-13 2021-07-07 バイエル・オーイュー 長時間作用型薬物送達装置および避妊におけるその使用
CN105056376A (zh) * 2015-08-21 2015-11-18 崔尚品 一种治疗宫颈炎和宫颈hpv感染的医疗器械
WO2019094625A1 (en) * 2017-11-09 2019-05-16 Nexien Biopharma, Inc. Methods and compositions for parenteral administration of cannabidiol in the treatment of convulsive disorders
CN110917478B (zh) * 2019-12-10 2020-11-24 河南省肿瘤医院 一种宫颈hpv感染用药物缓释器
US11338119B2 (en) * 2020-03-20 2022-05-24 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
US11344526B2 (en) * 2020-03-20 2022-05-31 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
US11173291B2 (en) * 2020-03-20 2021-11-16 The Regents Of The University Of California Implantable drug delivery devices for localized drug delivery
WO2022029780A1 (en) * 2020-08-06 2022-02-10 Bless Medical Ltd. Intrauterine device for controlled drug release
US20230047191A1 (en) * 2021-08-05 2023-02-16 Celanese Eva Performance Polymers Llc Implantable Medical Device for the Delivery of Bisphosphonate

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3996934A (en) * 1971-08-09 1976-12-14 Alza Corporation Medical bandage
US4155991A (en) * 1974-10-18 1979-05-22 Schering Aktiengesellschaft Vaginal ring
DE3040978A1 (de) * 1980-10-28 1982-05-27 Schering Ag, 1000 Berlin Und 4619 Bergkamen Vaginalring
US4601893A (en) * 1984-02-08 1986-07-22 Pfizer Inc. Laminate device for controlled and prolonged release of substances to an ambient environment and method of use
EP0180264A1 (en) * 1984-10-12 1986-05-07 Akzo N.V. Release system for two or more active substances
US4666441A (en) * 1985-12-17 1987-05-19 Ciba-Geigy Corporation Multicompartmentalized transdermal patches
US5538736A (en) * 1987-04-28 1996-07-23 Lts Lohmann Therapie-Systeme Gmbh Active substance-containing plaster for the controlled administration of active substances to the skin
ES2054784T3 (es) * 1987-08-08 1994-08-16 Akzo Nv Un metodo para la fabricacion de un implante.
US5064422A (en) * 1990-10-18 1991-11-12 Bertek, Inc. Twin patch applicator
FI95768C (fi) * 1993-06-17 1996-03-25 Leiras Oy Emättimensisäinen antosysteemi
US5443461A (en) * 1993-08-31 1995-08-22 Alza Corporation Segmented device for simultaneous delivery of multiple beneficial agents
US5660848A (en) * 1994-11-02 1997-08-26 The Population Council, Center For Biomedical Research Subdermally implantable device
US5972372A (en) * 1996-07-31 1999-10-26 The Population Council, Inc. Intravaginal rings with insertable drug-containing core
AU742372B2 (en) * 1997-06-04 2002-01-03 Debio Recherche Pharmaceutique S.A. Implants for controlled release of pharmaceutically active principles and method for making same
US6039968A (en) * 1997-06-24 2000-03-21 Hoechst Marion Roussel Intravaginal drug delivery device
US6117442A (en) * 1998-11-12 2000-09-12 Leiras Oy Drug delivery device, especially for the delivery of androgens
US6063395A (en) * 1998-11-12 2000-05-16 Leiras Oy Drug delivery device especially for the delivery of progestins and estrogens
US6476079B1 (en) * 1999-12-23 2002-11-05 Leiras Oy Devices for the delivery of drugs having antiprogestinic properties
US6436428B1 (en) * 2000-03-21 2002-08-20 Enhance Pharmaceuticals, Inc. Device and method for treating urinary incontinence in females

Also Published As

Publication number Publication date
CA2457979A1 (en) 2003-03-06
AR036310A1 (es) 2004-08-25
KR20040036928A (ko) 2004-05-03
US20040247674A1 (en) 2004-12-09
RU2302883C2 (ru) 2007-07-20
JP2005503389A (ja) 2005-02-03
NO20041315L (no) 2004-03-30
WO2003017971A1 (en) 2003-03-06
CN1549703A (zh) 2004-11-24
EP1427390A1 (en) 2004-06-16
CN1289064C (zh) 2006-12-13
HUP0401438A3 (en) 2008-04-28
PL367961A1 (en) 2005-03-07
AU2002313517B2 (en) 2007-09-06
RU2004109575A (ru) 2005-08-20
HUP0401438A2 (hu) 2004-11-29

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