PE20030932A1 - Composiciones de medicamentos que, junto a agentes anticolinergicos, contienen compuestos heterociclicos - Google Patents
Composiciones de medicamentos que, junto a agentes anticolinergicos, contienen compuestos heterociclicosInfo
- Publication number
- PE20030932A1 PE20030932A1 PE2003000141A PE2003000141A PE20030932A1 PE 20030932 A1 PE20030932 A1 PE 20030932A1 PE 2003000141 A PE2003000141 A PE 2003000141A PE 2003000141 A PE2003000141 A PE 2003000141A PE 20030932 A1 PE20030932 A1 PE 20030932A1
- Authority
- PE
- Peru
- Prior art keywords
- phenyl
- methyl
- bridge
- ethyl
- link
- Prior art date
Links
- 229940079593 drug Drugs 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title abstract 3
- 229940121948 Muscarinic receptor antagonist Drugs 0.000 title abstract 2
- 239000000812 cholinergic antagonist Substances 0.000 title abstract 2
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical class [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 5
- -1 n-BUTYL Chemical class 0.000 abstract 5
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical group [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 3
- QUPDWYMUPZLYJZ-UHFFFAOYSA-N ethyl Chemical class C[CH2] QUPDWYMUPZLYJZ-UHFFFAOYSA-N 0.000 abstract 3
- VXNZUUAINFGPBY-UHFFFAOYSA-N 1-Butene Chemical class CCC=C VXNZUUAINFGPBY-UHFFFAOYSA-N 0.000 abstract 1
- OEXHQOGQTVQTAT-SSZRJXQFSA-N [(1r,5s)-8-methyl-8-propan-2-yl-8-azoniabicyclo[3.2.1]octan-3-yl] (2r)-3-hydroxy-2-phenylpropanoate Chemical class C1([C@H](CO)C(=O)OC2C[C@H]3CC[C@@H](C2)[N+]3(C)C(C)C)=CC=CC=C1 OEXHQOGQTVQTAT-SSZRJXQFSA-N 0.000 abstract 1
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000000816 ethylene group Chemical group [H]C([H])([*:1])C([H])([H])[*:2] 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical group [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 230000000414 obstructive effect Effects 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
- 210000002345 respiratory system Anatomy 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 150000005846 sugar alcohols Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
SE REFIERE A MEDICAMENTOS QUE CONTIENEN AGENTES ANTICOLINERGICOS TAL COMO SALES DE TIOTROPIO, OXITROPIO, IPRATROPIO EN COMBINACION CON COMPUESTOS DE FORMULA 2; DONDE R1 ES H, METILO, ETILO, n-BUTILO, ENTRE OTROS; R2 ES H, METILO, ETILO, O JUNTO A R1 FORMAN UN PUENTE BUTIELNO, PENTILENO; O JUNTO A R13 ES UN ENLACE SIMPLE, PUENTE BUTILENO; R3 ES H; R4 ES METOXI; R5 ES CICLOHEXILO, FENILO, 3-METOXICARBONIL-FENILO, ENTRE OTROS; A ES O. CH2; B ES O, CR12R13, CHR15CHR17; D ES CH2CH2, CH(Ph)CH2, CONH, ENTRE OTROS; R12 ES H, METILO, ETILO, FENILO, CH2CORx, ENTRE OTROS; R3 ES H O JUNTO A R2 ES UN ENLACE, PUENTE BUTILENO; R15 ES H, O JUNTO A R17 ES UN ENLACE; R17 ES H, R18 ES H, METILO; R19 ES H, METOXI, FENILO, CN; R19a ES H, METILO, FENILO; Rx ES HIDROXI, ETOXI, BENCILOXI, 2-FENIL-ETILOXI, ENTRE OTROS; X ES CH2, S, NH; Y ES CH, CCN, CCOOEt, CHCONH; SUSTANCIAS AUXILIARES DE PREFERENCIA MONOSACARIDOS; DISACARIDOS, POLISACARIDOS, POLIALCOHOLES, SIENDO EL TAMANO DE PARTICULAS DE 250 µM; SIENDO LA RELACION DE 1) A 2) DE 1:300 A 50:1. EL MEDICAMENTO PUEDE SER UTIL PARA EL TRATAMIENTO DE ENFERMEDADES INFLAMATORIAS, OBSTRUCTIVAS DE LAS VIAS RESPIRATORIAS
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10205274A DE10205274A1 (de) | 2002-02-08 | 2002-02-08 | Neue Arzneimittelkompositionen enthaltend neben Anticholinergika heterocyclische Verbindungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20030932A1 true PE20030932A1 (es) | 2003-12-15 |
Family
ID=27618465
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2003000141A PE20030932A1 (es) | 2002-02-08 | 2003-02-07 | Composiciones de medicamentos que, junto a agentes anticolinergicos, contienen compuestos heterociclicos |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20030203918A1 (es) |
| AR (1) | AR038824A1 (es) |
| AU (1) | AU2003205717A1 (es) |
| DE (1) | DE10205274A1 (es) |
| PE (1) | PE20030932A1 (es) |
| TW (1) | TW200303866A (es) |
| UY (1) | UY27651A1 (es) |
| WO (1) | WO2003066044A1 (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7250426B2 (en) * | 2002-11-29 | 2007-07-31 | Boehringer Ingelheim Pharma Gmbh & Co Kg | Tiotropium-containing pharmaceutical combination for inhalation |
| MXPA05009921A (es) * | 2003-03-17 | 2005-11-04 | Kyowa Hakko Kogyo Kk | Agentes terapeuticos y/o preventivos para enfermedades cutaneas cronicas. |
| US20060239927A1 (en) * | 2003-03-31 | 2006-10-26 | Kyowa Hakko Kogyo Co., | Drug for airway administration |
| JPWO2004087148A1 (ja) * | 2003-03-31 | 2006-06-29 | 協和醗酵工業株式会社 | 肺疾患の治療および／または予防剤 |
| JPWO2004087149A1 (ja) * | 2003-03-31 | 2006-06-29 | 協和醗酵工業株式会社 | 医薬組成物 |
| JPWO2004087147A1 (ja) * | 2003-03-31 | 2006-06-29 | 協和醗酵工業株式会社 | 肺疾患の治療および／または予防剤 |
| JPWO2004087151A1 (ja) * | 2003-03-31 | 2006-06-29 | 協和醗酵工業株式会社 | 医薬組成物 |
| WO2004087150A1 (ja) * | 2003-03-31 | 2004-10-14 | Kyowa Hakko Kogyo Co. Ltd. | 医薬組成物 |
| US7435837B2 (en) * | 2003-10-24 | 2008-10-14 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
| US20050261347A1 (en) * | 2003-10-24 | 2005-11-24 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
| CA2661850A1 (en) | 2006-09-01 | 2008-03-06 | Kyorin Pharmaceutical Co., Ltd. | Pyrazolopyridine carboxamide derivative and phosphodiesterase (pde) inhibitor containing the same |
| EP2060572A4 (en) | 2006-09-06 | 2010-11-17 | Kyorin Seiyaku Kk | PYRAZOLOPYRIDINE DERIVATIVE AND PHOSPHODESTERASE INHIBITOR (PDE) WHICH CONTAINS IT AS ACTIVE MATTER |
| KR20170016894A (ko) * | 2014-06-23 | 2017-02-14 | 레오 파마 에이/에스 | 1,3-벤조디옥솔 헤테로사이클릭 화합물의 제조 방법 |
| PL3390407T3 (pl) | 2015-12-18 | 2024-01-29 | UNION therapeutics A/S | Sposoby otrzymywania heterocyklicznych związków 1,3-benzodioksolu |
| MX394835B (es) | 2017-06-20 | 2025-03-24 | Union Therapeutics As | Metodos para la preparacion de compuestos heterociclicos de 1,3-benzodioxol. |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0828728B1 (de) * | 1995-05-18 | 2003-01-22 | ALTANA Pharma AG | Phenyldihydrobenzofurane |
| PT771794E (pt) * | 1995-05-19 | 2006-09-29 | Kyowa Hakko Kogyo Kk | Compostos heterociclicos contendo oxigenio |
-
2002
- 2002-02-08 DE DE10205274A patent/DE10205274A1/de not_active Withdrawn
-
2003
- 2003-01-31 WO PCT/EP2003/000961 patent/WO2003066044A1/de not_active Application Discontinuation
- 2003-01-31 AU AU2003205717A patent/AU2003205717A1/en not_active Abandoned
- 2003-02-05 UY UY27651A patent/UY27651A1/es not_active Application Discontinuation
- 2003-02-05 US US10/358,947 patent/US20030203918A1/en not_active Abandoned
- 2003-02-07 TW TW092102525A patent/TW200303866A/zh unknown
- 2003-02-07 AR ARP030100387A patent/AR038824A1/es not_active Suspension/Interruption
- 2003-02-07 PE PE2003000141A patent/PE20030932A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003066044A1 (de) | 2003-08-14 |
| AR038824A1 (es) | 2005-01-26 |
| US20030203918A1 (en) | 2003-10-30 |
| UY27651A1 (es) | 2003-09-30 |
| AU2003205717A1 (en) | 2003-09-02 |
| TW200303866A (en) | 2003-09-16 |
| DE10205274A1 (de) | 2003-08-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application declared void or lapsed |