PE20020305A1 - 2-(4-PIRIDIL) AMINO-6-DIALCOXIFENIL-PIRIDO [2,3-d] PIRIMIDIN-7-ONAS COMO INHIBIDORES DE LA TIROSINA QUINASA - Google Patents
2-(4-PIRIDIL) AMINO-6-DIALCOXIFENIL-PIRIDO [2,3-d] PIRIMIDIN-7-ONAS COMO INHIBIDORES DE LA TIROSINA QUINASAInfo
- Publication number
- PE20020305A1 PE20020305A1 PE2001000776A PE2001000776A PE20020305A1 PE 20020305 A1 PE20020305 A1 PE 20020305A1 PE 2001000776 A PE2001000776 A PE 2001000776A PE 2001000776 A PE2001000776 A PE 2001000776A PE 20020305 A1 PE20020305 A1 PE 20020305A1
- Authority
- PE
- Peru
- Prior art keywords
- pyrimidin
- alkyl
- dialcoxyphenyl
- onas
- pyridyl
- Prior art date
Links
- -1 4-PYRIDYL Chemical class 0.000 title abstract 3
- 102000004022 Protein-Tyrosine Kinases Human genes 0.000 title abstract 2
- 108090000412 Protein-Tyrosine Kinases Proteins 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- SCVJRXQHFJXZFZ-KVQBGUIXSA-N 2-amino-9-[(2r,4s,5r)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3h-purine-6-thione Chemical compound C1=2NC(N)=NC(=S)C=2N=CN1[C@H]1C[C@H](O)[C@@H](CO)O1 SCVJRXQHFJXZFZ-KVQBGUIXSA-N 0.000 abstract 1
- 230000004663 cell proliferation Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical class [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
SE REFIERE A 2-(4-PIRIDIL) AMINO-6-DIALCOXIFENIL-PIRIDO [2,3-d] PIRIMIDIN-7-ONAS DE FORMULA I DONDE R1, R2, R5 Y R6 SON H, HALO, ALQUILO C1-C6, ALCOXI C1-C6, TIOALQUILO, HIDROXI, ALCANOILO C1-C6, ALCOXI C1-C6, TIO, TIOALQUILO, ENTRE OTROS; R3 Y R4 SON ALQUILO C1-C6, HALOALQUILO C1-C6; R7 ES H, ALQUILO C1-C6, ALQUENILO C2-C6, ALQUINILO C2-C6, CILOALQUILO C3-C6. SON COMPUESTOS PREFERIDOS 6-(3,5-DIMETOXI-FENIL)-2-(2-METIL-PIRIDIN-4-ILAMINO)-8-ETIL-8H-PIRIDO[2,3-d]PIRIMIDIN-7-ONA, 6-(3,5-DIMETOXI-FENIL)-2-(2,6-DIMETIL-PIRIDIN-4-ILAMINO)-8-ETIL-8H-PIRIDO[2,3-d]PIRIMIDIN-7-ONA, 6-(3,5-DIMETOXI-FENIL)-2-(2-CLORO-PIRIDIN-4-ILAMINO)-8-ETIL-8H-PIRIDO[2,3-d]PIRIMIDIN-7-ONA, ENTRE OTROS. SE REFIERE TAMBIEN A UNA COMPOSICION FARMACEUTICA. LOS COMPUESTOS 2-(4-PIRIDIL) AMINO-6-DIALCOXIFENIL-PIRIDO [2,3-d] PIRIMIDIN-7-ONAS SON INHIBIDORES DE LA TIROSINA QUINASA UTILES PARA TRATAR ENFERMEDADES DERIVADAS DE LA PROLIFERACION CELULAR COMO CANCER, ATEROSCLEROSIS, RESTENOSIS, ARTRITIS REUMATOIDE
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22308300P | 2000-08-04 | 2000-08-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20020305A1 true PE20020305A1 (es) | 2002-05-09 |
Family
ID=22834955
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2001000776A PE20020305A1 (es) | 2000-08-04 | 2001-08-03 | 2-(4-PIRIDIL) AMINO-6-DIALCOXIFENIL-PIRIDO [2,3-d] PIRIMIDIN-7-ONAS COMO INHIBIDORES DE LA TIROSINA QUINASA |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US7022711B2 (es) |
| EP (1) | EP1307450B1 (es) |
| JP (1) | JP2004519422A (es) |
| AP (1) | AP1333A (es) |
| AR (1) | AR030310A1 (es) |
| AT (1) | ATE408613T1 (es) |
| AU (1) | AU2001277032A1 (es) |
| BR (1) | BR0112857A (es) |
| CA (1) | CA2417942C (es) |
| DE (1) | DE60135854D1 (es) |
| DO (1) | DOP2001000227A (es) |
| ES (1) | ES2311532T3 (es) |
| GT (1) | GT200100158A (es) |
| HN (1) | HN2001000171A (es) |
| MX (1) | MXPA02011263A (es) |
| PA (1) | PA8524101A1 (es) |
| PE (1) | PE20020305A1 (es) |
| SV (1) | SV2002000572A (es) |
| TN (1) | TNSN01118A1 (es) |
| UY (1) | UY26867A1 (es) |
| WO (1) | WO2002012238A2 (es) |
Families Citing this family (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE303385T1 (de) * | 2000-08-04 | 2005-09-15 | Warner Lambert Co | Verfahren zur herstellung von 2-(4-pyridyl)amino- 6-dialkylolxaphenyl-pyrido(2,3-d)pyrimidon-7-on derivaten |
| US6960662B2 (en) * | 2000-08-04 | 2005-11-01 | Warner-Lambert Company | Process for preparing 2-(4-pyridyl)amino-6-dialkyloxyphenyl-pyrido[2,3-d]pyrimidin-7-ones |
| AU2003237009B2 (en) * | 2002-01-22 | 2008-10-02 | Warner-Lambert Company Llc | 2-(pyridin-2-ylamino)-pyrido[2,3d]pyrimidin-7-ones |
| US7196090B2 (en) * | 2002-07-25 | 2007-03-27 | Warner-Lambert Company | Kinase inhibitors |
| AU2003258542A1 (en) * | 2002-07-29 | 2004-02-23 | Axxima Pharmaceuticals Ag | Method for isolating atp binding proteins by means of immobolized protein inhibitors |
| US7098332B2 (en) * | 2002-12-20 | 2006-08-29 | Hoffmann-La Roche Inc. | 5,8-Dihydro-6H-pyrido[2,3-d]pyrimidin-7-ones |
| CN100420687C (zh) * | 2002-12-20 | 2008-09-24 | 霍夫曼-拉罗奇有限公司 | 作为选择性kdr和fgfr抑制剂的吡啶并[2,3-d]嘧啶衍生物 |
| CN1894234A (zh) | 2003-03-25 | 2007-01-10 | 武田药品工业株式会社 | 二肽基肽酶抑制剂 |
| EP1625122A1 (en) | 2003-05-14 | 2006-02-15 | Takeda San Diego, Inc. | Dipeptidyl peptidase inhibitors |
| US7678909B1 (en) | 2003-08-13 | 2010-03-16 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| US7169926B1 (en) | 2003-08-13 | 2007-01-30 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| US7723344B2 (en) | 2003-08-13 | 2010-05-25 | Takeda San Diego, Inc. | Dipeptidyl peptidase inhibitors |
| EP1699777B1 (en) | 2003-09-08 | 2012-12-12 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| AU2004289304A1 (en) * | 2003-11-10 | 2005-05-26 | Synta Pharmaceuticals, Corp. | Pyridine compounds |
| JP5520433B2 (ja) | 2004-01-21 | 2014-06-11 | エモリー ユニバーシティー | 病原体感染を処置するためのチロシンキナーゼインヒビターの組成物および使用 |
| US7732446B1 (en) | 2004-03-11 | 2010-06-08 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| EA013427B1 (ru) | 2004-03-15 | 2010-04-30 | Такеда Фармасьютикал Компани Лимитед | Ингибиторы дипептидилпептидазы |
| WO2005118555A1 (en) | 2004-06-04 | 2005-12-15 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| FR2873118B1 (fr) | 2004-07-15 | 2007-11-23 | Sanofi Synthelabo | Derives de pyrido-pyrimidine, leur application en therapeutique |
| WO2006019965A2 (en) | 2004-07-16 | 2006-02-23 | Takeda San Diego, Inc. | Dipeptidyl peptidase inhibitors |
| WO2006038112A1 (en) * | 2004-10-01 | 2006-04-13 | Warner-Lambert Company Llc | Use of kinase inhibitors to promote neochondrogenesis |
| EP1828192B1 (en) | 2004-12-21 | 2014-12-03 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| FR2887882B1 (fr) | 2005-07-01 | 2007-09-07 | Sanofi Aventis Sa | Derives de pyrido[2,3-d] pyrimidine, leur preparation, leur application en therapeutique |
| AU2006290205B2 (en) | 2005-09-14 | 2012-12-13 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors for treating diabetes |
| CN101360723A (zh) | 2005-09-16 | 2009-02-04 | 武田药品工业株式会社 | 制备嘧啶二酮衍生物的方法 |
| FR2896246B1 (fr) * | 2006-01-13 | 2008-08-15 | Sanofi Aventis Sa | Derives de pyrido-pyrimidone, leur preparation, leur application en therapeutique. |
| WO2007112347A1 (en) | 2006-03-28 | 2007-10-04 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| ES2370873T3 (es) * | 2006-09-13 | 2011-12-23 | Takeda Pharmaceutical Company Limited | Utilización del 2-6-(3-amino-piperidin-1-il)-3-metil-2,4-dioxo-3,4-dihidro-2h-pirimidin-1-ilmetil-4-fluoro-benzonitrilo para el tratamiento de la diabetes, el cáncer, los trastornos autoinmunitarios y la infección por el vih. |
| US8324383B2 (en) | 2006-09-13 | 2012-12-04 | Takeda Pharmaceutical Company Limited | Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile |
| EP2094698A1 (en) * | 2006-11-09 | 2009-09-02 | F. Hoffmann-Roche AG | Substituted 6-phenyl-pyrido [2,3-d]pyrimidin-7-one derivatives as kinase inhibitors and methods for using the same |
| TW200838536A (en) | 2006-11-29 | 2008-10-01 | Takeda Pharmaceutical | Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor |
| MX2009006706A (es) | 2006-12-22 | 2009-07-02 | Astex Therapeutics Ltd | Compuestos heterociclicos biciclicos como inhibidores del receptor del factor de crecimiento de fibroblastos. |
| US8131527B1 (en) | 2006-12-22 | 2012-03-06 | Astex Therapeutics Ltd. | FGFR pharmacophore compounds |
| JP5442449B2 (ja) | 2006-12-22 | 2014-03-12 | アステックス、セラピューティックス、リミテッド | 新規化合物 |
| FR2910813B1 (fr) | 2006-12-28 | 2009-02-06 | Sanofi Aventis Sa | Nouvelle utilisation therapeutique pour le traitement des leucemies |
| WO2008104473A2 (en) * | 2007-02-28 | 2008-09-04 | F. Hoffmann-La Roche Ag | Pyrazolopyriidine derivatives and their use as kinase inhibitors |
| US8093236B2 (en) | 2007-03-13 | 2012-01-10 | Takeda Pharmaceuticals Company Limited | Weekly administration of dipeptidyl peptidase inhibitors |
| GB0720038D0 (en) | 2007-10-12 | 2007-11-21 | Astex Therapeutics Ltd | New compounds |
| GB0720041D0 (en) | 2007-10-12 | 2007-11-21 | Astex Therapeutics Ltd | New Compounds |
| GB0810902D0 (en) | 2008-06-13 | 2008-07-23 | Astex Therapeutics Ltd | New compounds |
| US20120189641A1 (en) | 2009-02-25 | 2012-07-26 | OSI Pharmaceuticals, LLC | Combination anti-cancer therapy |
| US8465912B2 (en) | 2009-02-27 | 2013-06-18 | OSI Pharmaceuticals, LLC | Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation |
| WO2010099138A2 (en) | 2009-02-27 | 2010-09-02 | Osi Pharmaceuticals, Inc. | Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation |
| JP2012519281A (ja) | 2009-02-27 | 2012-08-23 | オーエスアイ・ファーマシューティカルズ，エルエルシー | 間葉様腫瘍細胞またはその生成を阻害する薬剤を同定するための方法 |
| GB0906470D0 (en) | 2009-04-15 | 2009-05-20 | Astex Therapeutics Ltd | New compounds |
| GB0906472D0 (en) | 2009-04-15 | 2009-05-20 | Astex Therapeutics Ltd | New compounds |
| CN101671336B (zh) | 2009-09-23 | 2013-11-13 | 辽宁利锋科技开发有限公司 | 芳杂环并嘧啶衍生物和类似物及其制备方法和用途 |
| KR101789129B1 (ko) | 2010-06-30 | 2017-11-20 | 후지필름 가부시키가이샤 | 신규 니코틴아미드 유도체 또는 그 염 |
| JP2014519813A (ja) | 2011-04-25 | 2014-08-21 | オーエスアイ・ファーマシューティカルズ，エルエルシー | 癌薬剤発見、診断、および治療におけるｅｍｔ遺伝子シグネチャーの使用 |
| WO2013152252A1 (en) | 2012-04-06 | 2013-10-10 | OSI Pharmaceuticals, LLC | Combination anti-cancer therapy |
| EP2872491B1 (en) * | 2012-07-11 | 2021-05-05 | Blueprint Medicines Corporation | Inhibitors of the fibroblast growth factor receptor |
| US9321786B2 (en) | 2013-03-15 | 2016-04-26 | Celgene Avilomics Research, Inc. | Heteroaryl compounds and uses thereof |
| ES2892423T3 (es) | 2013-03-15 | 2022-02-04 | Celgene Car Llc | Compuestos de heteroarilo y usos de los mismos |
| CN105307657B (zh) | 2013-03-15 | 2020-07-10 | 西建卡尔有限责任公司 | 杂芳基化合物和其用途 |
| CN105658642B (zh) | 2013-10-25 | 2019-05-03 | 蓝图药品公司 | 纤维母细胞生长因子受体抑制剂 |
| WO2015108992A1 (en) | 2014-01-15 | 2015-07-23 | Blueprint Medicines Corporation | Heterobicyclic compounds and their use as fgfr4 receptor inhibitors |
| KR20170032244A (ko) | 2014-07-26 | 2017-03-22 | 선샤인 레이크 파르마 컴퍼니 리미티드 | Cdk 저해제로서 2-아미노-피리도[2,3-d]피리미딘-7(8h)-온 유도체 및 그 용도 |
| US10449195B2 (en) | 2016-03-29 | 2019-10-22 | Shenzhen Pharmacin Co., Ltd. | Pharmaceutical formulation of palbociclib and a preparation method thereof |
| MX383803B (es) * | 2016-07-01 | 2025-03-14 | G1 Therapeutics Inc | Sintesis de n-(heteroaril)-pirrolo[3,2-d]pirimidin-2-aminas. |
| AU2018226315B2 (en) * | 2017-02-27 | 2021-01-28 | Betta Pharmaceuticals Co., Ltd. | FGFR inhibitor and application thereof |
| WO2020041770A1 (en) | 2018-08-24 | 2020-02-27 | G1 Therapeutics, Inc. | Improved synthesis of 1,4-diazaspiro[5.5]undecan-3-one |
| KR102531596B1 (ko) * | 2018-09-14 | 2023-05-11 | 아비스코 테라퓨틱스 컴퍼니 리미티드 | Fgfr억제제, 그 제조 방법 및 용도 |
| EP3902801A4 (en) * | 2018-12-28 | 2022-12-14 | SPV Therapeutics Inc. | Cyclin-dependent kinase inhibitors |
| CN114306245A (zh) | 2020-09-29 | 2022-04-12 | 深圳市药欣生物科技有限公司 | 无定形固体分散体的药物组合物及其制备方法 |
| WO2022150415A1 (en) * | 2021-01-06 | 2022-07-14 | The Penn State Research Foundation | Methods and materials for treating hair loss |
| US12268677B2 (en) | 2022-04-27 | 2025-04-08 | The Penn State Research Foundation | 4-aminopyridine (4-AP) and bone morphogenetic protein 2 (BMP-2) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5620981A (en) * | 1995-05-03 | 1997-04-15 | Warner-Lambert Company | Pyrido [2,3-D]pyrimidines for inhibiting protein tyrosine kinase mediated cellular proliferation |
| US5945422A (en) | 1997-02-05 | 1999-08-31 | Warner-Lambert Company | N-oxides of amino containing pyrido 2,3-D! pyrimidines |
| US6960662B2 (en) * | 2000-08-04 | 2005-11-01 | Warner-Lambert Company | Process for preparing 2-(4-pyridyl)amino-6-dialkyloxyphenyl-pyrido[2,3-d]pyrimidin-7-ones |
| ATE303385T1 (de) * | 2000-08-04 | 2005-09-15 | Warner Lambert Co | Verfahren zur herstellung von 2-(4-pyridyl)amino- 6-dialkylolxaphenyl-pyrido(2,3-d)pyrimidon-7-on derivaten |
-
2001
- 2001-07-20 AT AT01954811T patent/ATE408613T1/de not_active IP Right Cessation
- 2001-07-20 EP EP01954811A patent/EP1307450B1/en not_active Expired - Lifetime
- 2001-07-20 AP APAP/P/2001/002230A patent/AP1333A/en active
- 2001-07-20 US US10/343,847 patent/US7022711B2/en not_active Expired - Fee Related
- 2001-07-20 BR BR0112857-4A patent/BR0112857A/pt not_active IP Right Cessation
- 2001-07-20 CA CA2417942A patent/CA2417942C/en not_active Expired - Fee Related
- 2001-07-20 JP JP2002518213A patent/JP2004519422A/ja active Pending
- 2001-07-20 WO PCT/US2001/022881 patent/WO2002012238A2/en active Application Filing
- 2001-07-20 ES ES01954811T patent/ES2311532T3/es not_active Expired - Lifetime
- 2001-07-20 DE DE60135854T patent/DE60135854D1/de not_active Expired - Lifetime
- 2001-07-20 MX MXPA02011263A patent/MXPA02011263A/es active IP Right Grant
- 2001-07-20 AU AU2001277032A patent/AU2001277032A1/en not_active Abandoned
- 2001-07-27 SV SV2001000572A patent/SV2002000572A/es not_active Application Discontinuation
- 2001-08-01 TN TNTNSN01118A patent/TNSN01118A1/en unknown
- 2001-08-03 UY UY26867A patent/UY26867A1/es not_active Application Discontinuation
- 2001-08-03 HN HN2001000171A patent/HN2001000171A/es unknown
- 2001-08-03 PE PE2001000776A patent/PE20020305A1/es not_active Application Discontinuation
- 2001-08-03 PA PA20018524101A patent/PA8524101A1/es unknown
- 2001-08-03 DO DO2001000227A patent/DOP2001000227A/es unknown
- 2001-08-03 AR ARP010103716A patent/AR030310A1/es not_active Application Discontinuation
- 2001-08-03 GT GT200100158A patent/GT200100158A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE60135854D1 (de) | 2008-10-30 |
| US7022711B2 (en) | 2006-04-04 |
| WO2002012238A3 (en) | 2002-05-10 |
| EP1307450B1 (en) | 2008-09-17 |
| AP2001002230A0 (en) | 2001-09-30 |
| ATE408613T1 (de) | 2008-10-15 |
| CA2417942C (en) | 2010-06-29 |
| CA2417942A1 (en) | 2002-02-14 |
| EP1307450A2 (en) | 2003-05-07 |
| DOP2001000227A (es) | 2002-12-15 |
| GT200100158A (es) | 2002-07-18 |
| MXPA02011263A (es) | 2003-03-10 |
| BR0112857A (pt) | 2005-02-09 |
| SV2002000572A (es) | 2002-07-18 |
| HN2001000171A (es) | 2001-09-21 |
| JP2004519422A (ja) | 2004-07-02 |
| AP1333A (en) | 2004-11-28 |
| AR030310A1 (es) | 2003-08-20 |
| ES2311532T3 (es) | 2009-02-16 |
| TNSN01118A1 (en) | 2005-11-10 |
| UY26867A1 (es) | 2001-10-25 |
| US20030220345A1 (en) | 2003-11-27 |
| PA8524101A1 (es) | 2002-10-24 |
| AU2001277032A1 (en) | 2002-02-18 |
| WO2002012238A2 (en) | 2002-02-14 |
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