GB1044649A - Improvements in or relating to the preservation of blood - Google Patents
Improvements in or relating to the preservation of bloodInfo
- Publication number
- GB1044649A GB1044649A GB19065/65A GB1906565A GB1044649A GB 1044649 A GB1044649 A GB 1044649A GB 19065/65 A GB19065/65 A GB 19065/65A GB 1906565 A GB1906565 A GB 1906565A GB 1044649 A GB1044649 A GB 1044649A
- Authority
- GB
- United Kingdom
- Prior art keywords
- blood
- preservation
- relating
- composition
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000008280 blood Substances 0.000 title abstract 3
- 210000004369 blood Anatomy 0.000 title abstract 3
- 238000004321 preservation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 2
- AUHDWARTFSKSAC-HEIFUQTGSA-N (2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-(6-oxo-1H-purin-9-yl)oxolane-2-carboxylic acid Chemical compound [C@]1([C@H](O)[C@H](O)[C@@H](CO)O1)(N1C=NC=2C(O)=NC=NC12)C(=O)O AUHDWARTFSKSAC-HEIFUQTGSA-N 0.000 abstract 1
- 229930024421 Adenine Natural products 0.000 abstract 1
- GFFGJBXGBJISGV-UHFFFAOYSA-N Adenine Chemical compound NC1=NC=NC2=C1N=CN2 GFFGJBXGBJISGV-UHFFFAOYSA-N 0.000 abstract 1
- KTVPXOYAKDPRHY-SOOFDHNKSA-N D-ribofuranose 5-phosphate Chemical compound OC1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O KTVPXOYAKDPRHY-SOOFDHNKSA-N 0.000 abstract 1
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 abstract 1
- 229930010555 Inosine Natural products 0.000 abstract 1
- UGQMRVRMYYASKQ-KQYNXXCUSA-N Inosine Chemical compound O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C2=NC=NC(O)=C2N=C1 UGQMRVRMYYASKQ-KQYNXXCUSA-N 0.000 abstract 1
- GRSZFWQUAKGDAV-UHFFFAOYSA-N Inosinic acid Natural products OC1C(O)C(COP(O)(O)=O)OC1N1C(NC=NC2=O)=C2N=C1 GRSZFWQUAKGDAV-UHFFFAOYSA-N 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 229960000643 adenine Drugs 0.000 abstract 1
- 229960001760 dimethyl sulfoxide Drugs 0.000 abstract 1
- RQFCJASXJCIDSX-UUOKFMHZSA-N guanosine 5'-monophosphate Chemical compound C1=2NC(N)=NC(=O)C=2N=CN1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O RQFCJASXJCIDSX-UUOKFMHZSA-N 0.000 abstract 1
- 235000013928 guanylic acid Nutrition 0.000 abstract 1
- 239000004226 guanylic acid Substances 0.000 abstract 1
- 229960003786 inosine Drugs 0.000 abstract 1
- 235000013902 inosinic acid Nutrition 0.000 abstract 1
- 239000004245 inosinic acid Substances 0.000 abstract 1
- 229940028843 inosinic acid Drugs 0.000 abstract 1
- -1 pentose phosphate ester Chemical class 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
1,044,649. Preserving blood. SCHWARZ BIORESEARCH Inc. May 6, 1965 [May 8, 1964], No. 19065/65. Heading A2D. The stability of A.C.D. preserved blood is increased by the addition thereto of a composition comprising (a) inosine, inosinic acid or guanylic acid, (b) adenine, and (c) a pentose phosphate ester, e.g. ribose-5 phosphate. Preferably the composition also includes dimethyl sulphoxide.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36615464A | 1964-05-08 | 1964-05-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1044649A true GB1044649A (en) | 1966-10-05 |
Family
ID=23441870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB19065/65A Expired GB1044649A (en) | 1964-05-08 | 1965-05-06 | Improvements in or relating to the preservation of blood |
Country Status (3)
| Country | Link |
|---|---|
| DE (1) | DE1492173A1 (en) |
| FR (1) | FR1455087A (en) |
| GB (1) | GB1044649A (en) |
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1983000436A1 (en) * | 1981-08-04 | 1983-02-17 | Gauri, Kailash, Kumar | Combined preparation with synergic effect |
| EP1458235A4 (en) * | 2001-11-16 | 2005-04-06 | Hemanext Llc | ADDITIVE SOLUTION FOR BLOOD CONSERVATION |
| US9801784B2 (en) | 2015-04-23 | 2017-10-31 | New Health Sciences, Inc. | Anaerobic blood storage containers |
| US9844615B2 (en) | 2009-10-12 | 2017-12-19 | New Health Sciences, Inc. | System for extended storage of red blood cells and methods of use |
| US9877476B2 (en) | 2013-02-28 | 2018-01-30 | New Health Sciences, Inc. | Gas depletion and gas addition devices for blood treatment |
| US9968718B2 (en) | 2011-03-28 | 2018-05-15 | New Health Sciences, Inc. | Method and system for removing oxygen and carbon dioxide during red cell blood processing using an inert carrier gas and manifold assembly |
| US10058091B2 (en) | 2015-03-10 | 2018-08-28 | New Health Sciences, Inc. | Oxygen reduction disposable kits, devices and methods of use thereof |
| US10065134B2 (en) | 2010-05-05 | 2018-09-04 | New Health Sciences, Inc. | Integrated leukocyte, oxygen and/or CO2 depletion, and plasma separation filter device |
| US10136635B2 (en) | 2010-05-05 | 2018-11-27 | New Health Sciences, Inc. | Irradiation of red blood cells and anaerobic storage |
| US10251387B2 (en) | 2010-08-25 | 2019-04-09 | New Health Sciences, Inc. | Method for enhancing red blood cell quality and survival during storage |
| US10537097B2 (en) * | 2010-02-16 | 2020-01-21 | Viacell, Llc | Methods for treating red blood cells |
| US10583192B2 (en) | 2016-05-27 | 2020-03-10 | New Health Sciences, Inc. | Anaerobic blood storage and pathogen inactivation method |
| US11013771B2 (en) | 2015-05-18 | 2021-05-25 | Hemanext Inc. | Methods for the storage of whole blood, and compositions thereof |
| US11284616B2 (en) | 2010-05-05 | 2022-03-29 | Hemanext Inc. | Irradiation of red blood cells and anaerobic storage |
| US12089589B2 (en) | 2009-10-12 | 2024-09-17 | Hemanext Inc. | Irradiation of red blood cells and anaerobic storage |
-
1965
- 1965-04-14 FR FR13306A patent/FR1455087A/en not_active Expired
- 1965-04-30 DE DE19651492173 patent/DE1492173A1/en active Pending
- 1965-05-06 GB GB19065/65A patent/GB1044649A/en not_active Expired
Cited By (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1983000436A1 (en) * | 1981-08-04 | 1983-02-17 | Gauri, Kailash, Kumar | Combined preparation with synergic effect |
| EP1458235A4 (en) * | 2001-11-16 | 2005-04-06 | Hemanext Llc | ADDITIVE SOLUTION FOR BLOOD CONSERVATION |
| US12089589B2 (en) | 2009-10-12 | 2024-09-17 | Hemanext Inc. | Irradiation of red blood cells and anaerobic storage |
| US9844615B2 (en) | 2009-10-12 | 2017-12-19 | New Health Sciences, Inc. | System for extended storage of red blood cells and methods of use |
| US10537097B2 (en) * | 2010-02-16 | 2020-01-21 | Viacell, Llc | Methods for treating red blood cells |
| US10065134B2 (en) | 2010-05-05 | 2018-09-04 | New Health Sciences, Inc. | Integrated leukocyte, oxygen and/or CO2 depletion, and plasma separation filter device |
| US10136635B2 (en) | 2010-05-05 | 2018-11-27 | New Health Sciences, Inc. | Irradiation of red blood cells and anaerobic storage |
| US11284616B2 (en) | 2010-05-05 | 2022-03-29 | Hemanext Inc. | Irradiation of red blood cells and anaerobic storage |
| US10251387B2 (en) | 2010-08-25 | 2019-04-09 | New Health Sciences, Inc. | Method for enhancing red blood cell quality and survival during storage |
| US9968718B2 (en) | 2011-03-28 | 2018-05-15 | New Health Sciences, Inc. | Method and system for removing oxygen and carbon dioxide during red cell blood processing using an inert carrier gas and manifold assembly |
| US10687526B2 (en) | 2013-02-28 | 2020-06-23 | Hemanext Inc. | Gas depletion and gas addition devices for blood treatment |
| US9877476B2 (en) | 2013-02-28 | 2018-01-30 | New Health Sciences, Inc. | Gas depletion and gas addition devices for blood treatment |
| US10058091B2 (en) | 2015-03-10 | 2018-08-28 | New Health Sciences, Inc. | Oxygen reduction disposable kits, devices and methods of use thereof |
| US11350626B2 (en) | 2015-03-10 | 2022-06-07 | Hemanext Inc. | Oxygen reduction disposable kits, devices and methods of use thereof (ORDKit) |
| US11375709B2 (en) | 2015-03-10 | 2022-07-05 | Hemanext Inc. | Oxygen reduction disposable kits, devices and methods of use thereof |
| US11638421B2 (en) | 2015-03-10 | 2023-05-02 | Hemanext Inc. | Oxygen reduction disposable kits, devices and methods of use thereof |
| US10849824B2 (en) | 2015-04-23 | 2020-12-01 | Hemanext Inc. | Anaerobic blood storage containers |
| US9801784B2 (en) | 2015-04-23 | 2017-10-31 | New Health Sciences, Inc. | Anaerobic blood storage containers |
| US12201584B2 (en) | 2015-04-23 | 2025-01-21 | Hemanext Inc. | Anaerobic blood storage containers |
| US11013771B2 (en) | 2015-05-18 | 2021-05-25 | Hemanext Inc. | Methods for the storage of whole blood, and compositions thereof |
| US11147876B2 (en) | 2016-05-27 | 2021-10-19 | Hemanext Inc. | Anaerobic blood storage and pathogen inactivation method |
| US10583192B2 (en) | 2016-05-27 | 2020-03-10 | New Health Sciences, Inc. | Anaerobic blood storage and pathogen inactivation method |
| US11911471B2 (en) | 2016-05-27 | 2024-02-27 | Hemanext Inc. | Anaerobic blood storage and pathogen inactivation method |
| US12364760B2 (en) | 2016-05-27 | 2025-07-22 | Hemanext Inc. | Anaerobic blood storage and pathogen inactivation method |
Also Published As
| Publication number | Publication date |
|---|---|
| FR1455087A (en) | 1966-04-01 |
| DE1492173A1 (en) | 1969-11-06 |
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