DK1042353T3 - 17-beta-aryl(arylmethyl)oxy(thio)alkylandrostanderivater - Google Patents

17-beta-aryl(arylmethyl)oxy(thio)alkylandrostanderivater

Info

Publication number: DK1042353T3
Authority: DK; Denmark
Prior art keywords: alkyl; independently hydrogen; arylmethyl; thio; oxy
Prior art date: 1997-12-18

Application number

DK98965821T

Other languages

English (en)

Inventor

Christian Heijmans

Der Louw Jaap Van

Original Assignee

Akzo Nobel Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-12-18

Filing date

1998-12-11

Publication date

2002-11-04

1998-12-11 Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv

2002-11-04 Application granted granted Critical

2002-11-04 Publication of DK1042353T3 publication Critical patent/DK1042353T3/da

Links

125000005002 aryl methyl group Chemical group 0.000 title 1
-1 oxy (thio) Chemical class 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
229910020008 S(O) Inorganic materials 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical group 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
229910004727 OSO3H Inorganic materials 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000035558 fertility Effects 0.000 abstract 1
150000002431 hydrogen Chemical group 0.000 abstract 1
230000021121 meiosis Effects 0.000 abstract 1
125000004043 oxo group Chemical group O=* 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
230000001105 regulatory effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/0065—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified
- C07J7/007—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified not substituted in position 17 alfa
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Steroid Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK98965821T 1997-12-18 1998-12-11 17-beta-aryl(arylmethyl)oxy(thio)alkylandrostanderivater DK1042353T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP97203998		1997-12-18
PCT/EP1998/008130 WO1999032506A1 (en)	1997-12-18	1998-12-11	17β-ARYL (ARYLMETHYL) OXY(THIO)ALKYL -ANDROSTANE DERIVATIVES

Publications (1)

Publication Number	Publication Date
DK1042353T3 true DK1042353T3 (da)	2002-11-04

Family

ID=8229080

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK98965821T DK1042353T3 (da)	1997-12-18	1998-12-11	17-beta-aryl(arylmethyl)oxy(thio)alkylandrostanderivater

Country Status (9)

Country	Link
US (1)	US6251887B1 (da)
EP (1)	EP1042353B1 (da)
JP (1)	JP2001526293A (da)
AT (1)	ATE220686T1 (da)
AU (1)	AU2160999A (da)
DE (1)	DE69806640T2 (da)
DK (1)	DK1042353T3 (da)
ES (1)	ES2181321T3 (da)
WO (1)	WO1999032506A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69903346T2 (de) *	1998-12-11	2003-01-30	Akzo Nobel N.V., Arnheim/Arnhem	22s-hydroxycholesta-8,14-dien derivate mit meiose regulierende aktivität
ES2204613T3 (es) *	1999-04-06	2004-05-01	Akzo Nobel N.V.	Androgenos 7-alfa alquilo oralmente activos.
EP1563309A2 (en) *	2002-11-14	2005-08-17	Novo Nordisk A/S	Use of nuclear hormone receptors to identify meiosis regulating compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5716777A (en)	1994-06-23	1998-02-10	Novo Nordisk A/S	Regulation of meiosis using sterols
AU717180B2 (en) *	1995-03-06	2000-03-16	Novo Nordisk A/S	Stimulation of meiosis
CA2224866A1 (en)	1995-06-23	1997-01-09	Novo Nordisk A/S	Meiosis regulating compounds
HUP0002331A3 (en) *	1997-05-16	2001-05-28	Akzo Nobel Nv	20-aralkyl-5alpha-pregnane derivatives and pharmaceutical compositions thereof
PL337188A1 (en)	1997-06-04	2000-08-14	Akzo Nobel Nv	Derivatives of 17beta - allyloxy (thio) alkyl - androstane for modulation of meiosis

1998
- 1998-12-11 AT AT98965821T patent/ATE220686T1/de not_active IP Right Cessation
- 1998-12-11 ES ES98965821T patent/ES2181321T3/es not_active Expired - Lifetime
- 1998-12-11 DE DE69806640T patent/DE69806640T2/de not_active Expired - Fee Related
- 1998-12-11 DK DK98965821T patent/DK1042353T3/da active
- 1998-12-11 US US09/581,749 patent/US6251887B1/en not_active Expired - Fee Related
- 1998-12-11 EP EP98965821A patent/EP1042353B1/en not_active Expired - Lifetime
- 1998-12-11 AU AU21609/99A patent/AU2160999A/en not_active Abandoned
- 1998-12-11 JP JP2000525443A patent/JP2001526293A/ja active Pending
- 1998-12-11 WO PCT/EP1998/008130 patent/WO1999032506A1/en active IP Right Grant

Also Published As

Publication number	Publication date
ATE220686T1 (de)	2002-08-15
JP2001526293A (ja)	2001-12-18
AU2160999A (en)	1999-07-12
WO1999032506A1 (en)	1999-07-01
US6251887B1 (en)	2001-06-26
EP1042353A1 (en)	2000-10-11
ES2181321T3 (es)	2003-02-16
DE69806640D1 (de)	2002-08-22
DE69806640T2 (de)	2003-03-13
EP1042353B1 (en)	2002-07-17

Publication	Publication Date	Title
PT1178045E (pt)	2003-10-31	Derivados de azaindole-etilamina como agentes de ligacao de receptores de acetilcolina nicotinicos
NO974890D0 (no)	1997-10-23	Radicicolderivater
NZ214156A (en)	1988-06-30	Quindone derivatives and pharmaceutical compositions
IL114785A0 (en)	1995-11-27	Pyrrolocarbazoles their preparation and pharmaceutical compositions containing them
NO995590D0 (no)	1999-11-15	20-Aryl-5<alfa>-pregnan-derivater
PL337188A1 (en)	2000-08-14	Derivatives of 17beta - allyloxy (thio) alkyl - androstane for modulation of meiosis
ES2055235T3 (es)	1994-08-16	Composicion anti-inflamatoria y/o antialergica que comprende derivados de glutation.
AU641686B2 (en)	1993-09-30	Benzanilides
DK1042353T3 (da)	2002-11-04	17-beta-aryl(arylmethyl)oxy(thio)alkylandrostanderivater
CA2010982A1 (en)	1990-08-31	Osteogenesis promotion with use of vitamin d derivatives
ATE184282T1 (de)	1999-09-15	Cyclopropan-derivate und diese enthaltende antivirale mittel
DK424888D0 (da)	1988-07-29	Naphthothiazepinderivater, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende saadanne derivater
FI850123A0 (fi)	1985-01-11	Selektiva, biologiskt aktiva 7-oxo-prostacyklinderivat samt framstaellningsfoerfarande foer dessa samt dessa innehaollande farmaceutiska kompositioner.
DE69303847D1 (de)	1996-09-05	Indolderivate
TW353071B (en)	1999-02-21	Chromene compounds with neutroleptic activity, their preparation and pharmaceutical compositions
DK1137660T3 (da)	2003-02-03	22S-hydroxycholesta-8,14-dienderivater med meioseregulerende aktivitet