+

DE69626041D1 - Fluoreszenzfarbstoffe des typs sulfobenz(e)indocyanine - Google Patents

Fluoreszenzfarbstoffe des typs sulfobenz(e)indocyanine

Info

Publication number
DE69626041D1
DE69626041D1 DE69626041T DE69626041T DE69626041D1 DE 69626041 D1 DE69626041 D1 DE 69626041D1 DE 69626041 T DE69626041 T DE 69626041T DE 69626041 T DE69626041 T DE 69626041T DE 69626041 D1 DE69626041 D1 DE 69626041D1
Authority
DE
Germany
Prior art keywords
sulfobenz
indocyanine
type
fluorescence dyes
dyes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69626041T
Other languages
English (en)
Inventor
Ciana Leopoldo Della
Andrea Grignani
Mariacristina Cassullo
Giuseppe Caputo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Innosense Srl
Original Assignee
Innosense Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innosense Srl filed Critical Innosense Srl
Application granted granted Critical
Publication of DE69626041D1 publication Critical patent/DE69626041D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/533Production of labelled immunochemicals with fluorescent label
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/0066Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain being part of a carbocyclic ring,(e.g. benzene, naphtalene, cyclohexene, cyclobutenene-quadratic acid)
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/80Fluorescent dyes, e.g. rhodamine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/815Test for named compound or class of compounds
    • Y10S436/817Steroids or hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Luminescent Compositions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Inks, Pencil-Leads, Or Crayons (AREA)
  • Detergent Compositions (AREA)
DE69626041T 1995-10-09 1996-10-08 Fluoreszenzfarbstoffe des typs sulfobenz(e)indocyanine Expired - Lifetime DE69626041D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT95MI002049A IT1276833B1 (it) 1995-10-09 1995-10-09 Coloranti fluorescenti della famiglia della solfo benz e indocianina
PCT/EP1996/004377 WO1997013810A1 (en) 1995-10-09 1996-10-08 SULFO BENZ[e]INDOCYANINE FLUORESCENT DYES

Publications (1)

Publication Number Publication Date
DE69626041D1 true DE69626041D1 (de) 2003-03-06

Family

ID=11372321

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69626041T Expired - Lifetime DE69626041D1 (de) 1995-10-09 1996-10-08 Fluoreszenzfarbstoffe des typs sulfobenz(e)indocyanine

Country Status (6)

Country Link
US (1) US6136612A (de)
EP (1) EP0876428B1 (de)
AU (1) AU706668B2 (de)
DE (1) DE69626041D1 (de)
IT (1) IT1276833B1 (de)
WO (1) WO1997013810A1 (de)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6593148B1 (en) 1994-03-01 2003-07-15 Li-Cor, Inc. Cyanine dye compounds and labeling methods
DE19717904A1 (de) 1997-04-23 1998-10-29 Diagnostikforschung Inst Säurelabile und enzymatisch spaltbare Farbstoffkonstrukte zur Diagnostik mit Nahinfrarotlicht und zur Therapie
KR100337169B1 (ko) 1998-07-20 2002-05-18 최중갑 복합염료 조성물을 이용한 폴리머 겔상의 dna의 검출방법 및
US7547721B1 (en) 1998-09-18 2009-06-16 Bayer Schering Pharma Ag Near infrared fluorescent contrast agent and fluorescence imaging
JP2000095758A (ja) * 1998-09-18 2000-04-04 Schering Ag 近赤外蛍光造影剤および蛍光造影方法
US6605434B1 (en) 1999-03-16 2003-08-12 Human Genome Sciences, Inc. Direct bacterial lysate sequencing
DE19937024A1 (de) * 1999-08-05 2001-02-08 Bayer Ag Verwendung von Acylsulfonamido substituierten Polymethin-Farbstoffen als Fluoreszenz-Farbstoffe und/oder Marker
US6934319B2 (en) * 1999-12-30 2005-08-23 Infineon Technologies Ag Configurable multimode despreader for spread spectrum applications
US6716994B1 (en) * 2000-01-04 2004-04-06 Applera Corporation Mobility-Modifying Cyanine Dyes
ATE392183T1 (de) * 2000-01-18 2008-05-15 Mallinckrodt Inc Hydrophile zyaninfarbstoffe
US7790144B2 (en) 2000-01-18 2010-09-07 Mallinckrodt Inc. Receptor-avid exogenous optical contrast and therapeutic agents
US7597878B2 (en) * 2000-09-19 2009-10-06 Li-Cor, Inc. Optical fluorescent imaging
ATE315066T1 (de) * 2000-09-19 2006-02-15 Li Cor Inc Cyaninfarbstoffe
US6656451B1 (en) * 2000-10-16 2003-12-02 Mallinckrodt, Inc. Indole compounds as novel dyes for organ function monitoring
US6335450B1 (en) * 2000-11-09 2002-01-01 Beckman Coulter, Inc. Efficient cyclic-bridged cyanine dyes
US6331632B1 (en) * 2000-11-09 2001-12-18 Beckman Coulter, Inc. Cyanine dye phosphoramidites
US6710363B1 (en) * 2000-11-27 2004-03-23 Uview Ultraviolet Systems, Inc. Detection lamp equipped with light-emitting diode
EP1211294B1 (de) * 2000-11-28 2008-08-13 Visen Medical, Inc. Verbessertes Verfahren und Methode zur Herstellung von asymmetrischen monofunktionalisierten Indocyaninmarkern sowie erhaltene Verbindungen
EP1209205A1 (de) 2000-11-28 2002-05-29 Innosense S.r.l. Verbesserte Verfahren und Methode zur Herstellung von asymmetrischen monofunktionalisierten Indocyaninmarkern sowie erhaltene Verbindungen
US6800438B2 (en) * 2000-12-28 2004-10-05 Xerox Corporation Imager for DNA sequencer
JP4319363B2 (ja) * 2001-01-15 2009-08-26 富士フイルム株式会社 ネガ型画像記録材料
US6706879B2 (en) 2001-02-28 2004-03-16 Stratagene Fluorescent dye
US20030124194A1 (en) * 2002-01-02 2003-07-03 Gaw Debra A. Amine functionalized superparamagnetic nanoparticles for the synthesis of bioconjugates and uses therefor
EP1485716A1 (de) * 2002-03-11 2004-12-15 Visen Medical, Inc. Sonden zur erzeugung von optischen bildern
US7091348B2 (en) * 2002-07-01 2006-08-15 Guava Technologies, Inc. Fluorescent dyes, energy transfer couples and methods
US20040132092A1 (en) * 2003-01-03 2004-07-08 Stetson Christopher M. Determining the density of functional moieties on polymer reagents
US20080102036A1 (en) * 2003-06-04 2008-05-01 Poss Kirtland G Biocompatible Fluorescent Silicon Nanoparticles
ITPZ20030002A1 (it) * 2003-08-12 2005-02-13 Giuseppe Caputo Composti del tipo cianina aventi un braccio di legame alchinilico
US8227621B2 (en) * 2005-06-30 2012-07-24 Li-Cor, Inc. Cyanine dyes and methods of use
EP1937676B1 (de) * 2005-09-02 2016-11-30 Visen Medical, Inc. Biologisch kompatible, fluoreszente mittel zur bilddarstellung
EP1934202B1 (de) 2005-09-02 2019-01-09 Visen Medical, Inc. Nah-infrarot-fluorophore, die sich von nicotinsäure und picolinsäure ableiten
CA2621137C (en) * 2005-09-02 2014-07-29 Visen Medical, Inc. Biocompatible n,n-disubstituted sulfonamide-containing fluorescent dye labels
WO2007136413A2 (en) 2005-12-22 2007-11-29 Visen Medical, Inc. Biocompatible fluorescent metal oxide nanoparticles
ATE500778T1 (de) 2005-12-22 2011-03-15 Visen Medical Inc Kombiniertes röntgen- und optisches tomographie- bildgebungssystem
ITSV20060002A1 (it) * 2006-01-19 2007-07-20 Ferrania Technologies Spa Colorante fluorescente di tipo cianinico
JP4958461B2 (ja) * 2006-03-30 2012-06-20 富士フイルム株式会社 近赤外吸収色素含有硬化性組成物
EP2044440A4 (de) * 2006-06-28 2014-04-02 Ge Healthcare Bio Sciences Ab Verfahren zum nachweis von wechselwirkungen zwischen proteinkomponenten
US8221721B2 (en) * 2007-02-09 2012-07-17 Visen Medical, Inc. Polycyclo dyes and use thereof
WO2008109832A2 (en) * 2007-03-08 2008-09-12 Visen Medical, Inc. Viable near-infrared fluorochrome labeled cells and methods of making and using same
KR20100017102A (ko) * 2007-05-16 2010-02-16 지이 헬스케어 에이에스 광학 조영제
CA2740602C (en) 2007-10-19 2017-05-02 Visen Medical, Inc. Imaging systems featuring waveguiding compensation
EP2244741B1 (de) 2008-01-18 2015-03-25 VisEn Medical, Inc. Fluoreszierende bildgebungsmittel
CA2715034C (en) 2008-03-14 2016-12-06 Visen Medical, Inc. Integrin targeting agents and in-vivo and in-vitro imaging methods using the same
US8864821B2 (en) 2008-11-26 2014-10-21 Visen Medical, Inc. Methods and compositions for identifying subjects at risk of developing stent thrombosis
AU2010236189B2 (en) * 2009-04-17 2015-01-29 Li-Cor, Inc. Fluorescent imaging with substituted cyanine dyes
US20110021908A1 (en) * 2009-05-27 2011-01-27 Lumicell Diagnostics, Inc. Methods and systems for spatially identifying abnormal cells
US9155471B2 (en) 2009-05-27 2015-10-13 Lumicell, Inc'. Methods and systems for spatially identifying abnormal cells
US8401618B2 (en) * 2009-08-28 2013-03-19 Visen Medical, Inc. Systems and methods for tomographic imaging in diffuse media using a hybrid inversion technique
CN102781307B (zh) * 2009-09-22 2016-01-20 文森医学公司 用于漫射性介质虚拟折射率匹配的系统和方法
JP5817073B2 (ja) * 2010-01-28 2015-11-18 国立大学法人三重大学 新規インドシアニン化合物を用いた診断用組成物及び分析方法
HUE041616T2 (hu) 2010-01-28 2019-05-28 National Univ Corporation Mie Univ Indocianin vegyület, szintézisének eljárása, tisztítási eljárása, indocianin vegyületet alkalmazó diagnosztikai készítmény, és készülék in vivo kinetika mérésére és készülék keringés megjelenítésére a diagnosztikai készítmény alkalmazásával
DE102010022110A1 (de) 2010-05-31 2011-12-01 LMU Universität München Department Chemie Cyaninfarbstoffe als Kontrastmittel zur Unterstützung der Augenchirurgie
WO2012054749A1 (en) 2010-10-20 2012-04-26 Li-Cor, Inc. Cyanine dyes and their conjugates
US9314304B2 (en) 2010-12-08 2016-04-19 Lumicell, Inc. Methods and system for image guided cell ablation with microscopic resolution
WO2012088007A1 (en) 2010-12-21 2012-06-28 Pierce Biotechnology, Inc. Fluorescent compounds
CN103687854A (zh) 2011-05-09 2014-03-26 文森医学公司 碳酸酐酶靶向剂及其使用方法
US8889884B1 (en) 2011-07-14 2014-11-18 Pierce Biotechnology, Inc. Phosphine derivatives of fluorescent compounds
US9249307B2 (en) 2011-08-16 2016-02-02 Pierce Biotechnology, Inc. Benzocyanine compounds
US9751868B2 (en) 2012-02-28 2017-09-05 Pierce Biotechnology, Inc. Benzocyanine compounds
US20140072515A9 (en) 2012-03-02 2014-03-13 Greg Hermanson Cyanine compounds
EP2831264B1 (de) 2012-03-30 2019-07-10 VisEn Medical, Inc. Bakterielle bildgebungsmittel und verfahren zur verwendung davon
WO2014028057A1 (en) 2012-08-15 2014-02-20 Visen Medical, Inc. Prostate specific antigen agents and methods of using same for prostate cancer imaging
US9676787B2 (en) 2012-08-28 2017-06-13 Pierce Biotechnology, Inc. Benzopyrylium compounds
US10743768B2 (en) 2012-10-15 2020-08-18 Visen Medical, Inc. Systems, methods, and apparatus for imaging of diffuse media featuring cross-modality weighting of fluorescent and bioluminescent sources
US9763577B2 (en) 2013-03-14 2017-09-19 Lumicell, Inc. Imaging agent for detection of diseased cells
EP2970674B1 (de) 2013-03-15 2018-12-12 VisEn Medical, Inc. 4,4-disubstituierte cyclohexyl-verbrückte heptamethin-cyanin-farbstoffe und verwendungen davon
JP6606487B2 (ja) 2013-03-15 2019-11-13 ビセン メディカル, インコーポレイテッド invitroおよびinvivoイメージングおよび検出のための置換シラキサンテニウム赤色〜近赤外蛍光色素
KR20160117440A (ko) 2013-12-31 2016-10-10 메모리얼 슬로안-케터링 캔서 센터 실시간 형광 소스들의 다채널 이미징을 위한 시스템들, 방법들 및 장치
CN107249647A (zh) 2014-12-15 2017-10-13 纪念斯隆-凯特琳癌症中心 具有增强的神经结合选择性的环状肽、与所述环状肽结合的纳米颗粒和此二者用于实时体内神经组织成像的用途
KR20180093961A (ko) 2015-12-15 2018-08-22 메모리얼 슬로안-케터링 캔서 센터 조직 구별, 예를 들어, 수술 중 시각화를 위한 영상화 시스템 및 방법
CA3045007A1 (en) 2016-11-30 2018-06-07 Memorial Sloan Kettering Cancer Center Inhibitor-functionalized ultrasmall nanoparticles and methods thereof
KR101973456B1 (ko) * 2017-10-17 2019-04-29 울산과학기술원 미토콘드리아에 표적화되는 수용성 화합물, 이를 포함하는 조성물 및 이의 제조방법
LV15619A (lv) * 2020-08-20 2022-02-20 Latvijas Organiskās Sintēzes Institūts Paņēmiens bioloģiski aktīvu savienojumu saistīšanas afinitātes pret kardiolipīnu noteikšanai
EP4015004A1 (de) 2020-12-18 2022-06-22 Phi Pharma SA Proteoglykanspezifische verzweigte peptide

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5230781A (en) * 1984-03-29 1993-07-27 Li-Cor, Inc. Sequencing near infrared and infrared fluorescence labeled DNA for detecting using laser diodes
US5268486A (en) * 1986-04-18 1993-12-07 Carnegie-Mellon Unversity Method for labeling and detecting materials employing arylsulfonate cyanine dyes
EP0288076B1 (de) * 1987-04-24 1991-09-04 EASTMAN KODAK COMPANY (a New Jersey corporation) Infrarotfilter-Farbstoffe für photographische Elemente
CA1337923C (en) * 1988-07-07 1996-01-16 Richard Lee Parton Infrared filter dye for photographic element
DE3912046B4 (de) * 1988-09-02 2004-03-25 Carnegie Mellon University Verfahren zum Markieren einer Komponente einer wäßrigen Flüssigkeit und lumineszenzphotostabiles Reaktionsprodukt
EP0433466B1 (de) * 1989-07-04 1994-12-14 Kabushiki Kaisha Kubota Betätigungsvorrichtung für kraftwagenkupplung
JP2663033B2 (ja) * 1990-02-22 1997-10-15 富士写真フイルム株式会社 ハロゲン化銀乳剤
EP0626427B1 (de) * 1993-05-26 2001-08-16 Agfa-Gevaert N.V. Im nahen Infrarot absorbierende Farbstoffe und diese enthaltende photographische Aufzeichnungselemente
US5453505A (en) * 1994-06-30 1995-09-26 Biometric Imaging, Inc. N-heteroaromatic ion and iminium ion substituted cyanine dyes for use as fluorescence labels

Also Published As

Publication number Publication date
ITMI952049A0 (de) 1995-10-09
WO1997013810A1 (en) 1997-04-17
US6136612A (en) 2000-10-24
AU706668B2 (en) 1999-06-17
EP0876428A1 (de) 1998-11-11
ITMI952049A1 (it) 1997-04-09
IT1276833B1 (it) 1997-11-03
AU7288296A (en) 1997-04-30
EP0876428B1 (de) 2004-11-17

Similar Documents

Publication Publication Date Title
DE69626041D1 (de) Fluoreszenzfarbstoffe des typs sulfobenz(e)indocyanine
DE69616584D1 (de) Fluoreszierende farbstoffmischungen
DE69618971D1 (de) Fluoreszierende farbstoffmischungen
DE59711530D1 (de) Färbemittel
DE69634963D1 (de) Fluorometer
DE59509353D1 (de) Haarfärbemittel
DE59608872D1 (de) Naphthalinlactamimid-Fluoreszenzfarbstoffe
DE69601845D1 (de) Farbstoffbehälter
DE59508925D1 (de) Oxidationshaarfärbemittel
DE69510971D1 (de) Monoazofarbstoffe
DE69816192D1 (de) Haarfärbemittel
DE59503964D1 (de) Disazofarbstoffe
DE69821203D1 (de) Haarfarbemittel
KR960007696A (ko) 2,4,6-트리아미노-3-시아노피리딘 커플링 성분을 함유하는 아조티오펜 염료
DE69407288D1 (de) Farbstoffbildempfangselement
DE59508671D1 (de) Cyaniminogruppen enthaltende Fluoreszenzfarbstoffe
FR2735138B1 (fr) Colorants reactifs de la serie des phtalocyanines
ATE276726T1 (de) Färbemittel
DE59808302D1 (de) Farbstoffzubereitungen
BR9803285A (pt) Misturas de corantes azo
DE19618586B8 (de) Monoazo-Dispersionsfarbstoffe
DE69707698D1 (de) Anthrachinonpolysulfonamidfarbstoffe
DE59508968D1 (de) Haarfärbemittel
DE59601762D1 (de) Pyridonmethidazofarbstoffe
DE59702493D1 (de) Dispersionsfarbstoffe

Legal Events

Date Code Title Description
8332 No legal effect for de
点击 这是indexloc提供的php浏览器服务,不要输入任何密码和下载