Device for collecting and separating tissue samples
Technical Field
The invention relates to the technical field of biomedicine, in particular to a device for collecting and separating tissue samples.
Background
Can carry out the endoscopic examination treatment through minimally invasive technique in the biomedical field, can suck out the tissue through the suction of endoscope, cooperate to collect separator and realize the collection to the sample, make things convenient for follow-up to inspect the sample, when carrying out the collection of polylith tissue, can carry out the collection of many storehouses to avoid depositing chaotic.
The tissue collector for disposable endoscope suction in the prior art 1 (Chinese patent disclosed by application No. CN201620962656.6,2017, 6 and 9) comprises a bottle body, a bottle cap, a gastroscope connecting catheter and an aspirator connecting catheter, wherein the bottle cap is rotationally connected with the bottle body, the gastroscope connecting catheter is connected to the bottle cap, the aspirator connecting catheter is inserted into the bottom of the bottle body, the bottom end of the gastroscope connecting catheter is leveled with the bottle cap, the gastroscope connecting catheter is communicated with the inside of the bottle body, and the gastroscope connecting catheter, the aspirator connecting catheter and the bottle cap are sealed; the lower part of the bottle body is a collecting chamber, the upper part of the bottle body is provided with a plurality of equal division grids, wherein three consecutive quarters are collecting grids, the bottom end of each collecting grid is provided with a filter screen which is integrally arranged with the grids, one consecutive quarter is a ventilation grid, the ventilation grid and each collecting grid are respectively and correspondingly communicated with a gastroscope connecting conduit, the collecting capacity of the collector is large, a plurality of collecting grids can collect a plurality of specimens of the same patient, the specimens are prevented from being lost, the tissue sample collecting and separating device in the prior art 2 (Chinese patent published by the application number of CN202011416705.3,2025 for 25 months) comprises a cup body, a cup cover and a plurality of inner cores, wherein a plurality of inner core inserting holes are arranged at the periphery of the cup body, the inner cores are inserted into the cup body in a pluggable manner through the inner core inserting holes, the cup cover is covered on the cup body to seal the cup body, the cup cover can rotate in a state of covering the cup body, a liquid inlet channel and a liquid outlet channel are arranged on the cup cover, the liquid inlet channel is arranged at the center position of the cup cover, the liquid inlet channel is arranged at a position close to the edge of the cup cover, and the cup cover is rotated to enable different inner cores to be aligned with the liquid inlet channels through rotating the cup body and the liquid inlet channel to be correspondingly rotated with the biopsy collecting device, the tissue sample collection device can collect tissue samples at different positions in different inner cores, can realize corresponding collection of the tissue samples at different positions, and is convenient to take out and detect after collection due to the design of the pluggable inner core.
The current tissue sample collection and separation device can realize the collection of classifying samples, but when the sample collection is switched and adjusted, the device is directly switched through a rotating mode, a gap exists at the rotating joint of the device due to the arrangement of the activity, the gap is easy to generate air leakage to influence the suction force of the device, and when the sample collection is switched, the suction force is continuously supplied, the sample is easily caused to be sucked down to the separation gap, the sample is caused to fall, the sample is taken out after the sample collection if the sample is required to be taken out, the operation of equipment is required to be stopped, the sample at other positions can be influenced by the taking of a single sample, and the use flexibility of the device is reduced.
Disclosure of Invention
The invention aims to provide a tissue sample collecting and separating device, which can be used for solving the problems that the existing tissue sample collecting and separating device provided by the background art can realize the classified collection of samples, but the sample collecting and separating device is directly switched in a rotating mode when the sample collecting is switched and regulated, a gap exists at the rotating joint of the device due to movable arrangement, the suction force of the device is easily influenced by air leakage at the gap, the suction force is continuously supplied when the sample collecting and switching is carried out, the sample is easily sucked into the separated gap to cause the sample to fall, and the operation of equipment is required to be stopped when the sample is required to be taken out after the sample is collected.
The tissue sample collecting and separating device comprises a shell and a cover body, wherein the cover body is detachably arranged above the shell, a collecting pipe is arranged above the cover body, the collecting pipe is connected with an endoscope suction cavity, a suction pipe is arranged in the middle of the cover body to provide suction force for the inside of the shell, a shielding ring is fixed in the middle of the shell, a partition plate is fixed on the outer side of the shielding ring, the partition plate is matched with the shielding ring to divide the shell into uniform spaces, a collecting box is arranged on the inner side of the partition plate, a filter plate for separating samples is arranged inside the collecting box, a butt joint mechanism is arranged between the collecting box and the shell, the collecting box is connected with the shell through the butt joint mechanism, a butt joint port is formed in the lower surface of the cover body, the butt joint port and the collecting box are correspondingly arranged, a sealing connection mechanism is arranged above the butt joint port, the butt joint port is connected with the collecting pipe through the sealing connection mechanism, and a movable adjusting mechanism is connected below the suction pipe.
Further optimize this technical scheme, constitute threaded connection between lid and the casing, and the outside of lid is regular polygon structural design, supplementary rotation of control lid.
Further optimizing the technical scheme, the docking mechanism comprises a mounting piece and a mounting groove;
the mounting piece is arranged at the lower part of the collecting box, the front end and the rear end of the mounting piece respectively penetrate through the front end and the rear end of the collecting box, and the mounting piece and the collecting box form rotary connection;
the mounting groove is formed in the surface of the shielding ring, and the mounting groove and the mounting piece are in threaded connection.
Further optimize this technical scheme, the outside of collecting the box is provided with sealed the pad, and the sealed pad seals its joint gap after collecting box and casing connection.
Further optimizing the technical scheme, the sealing connection mechanism comprises a sealing ring, a communication port and a pressing mechanism;
the sealing ring is fixed below the collecting pipe, is of an annular structure design and is movably connected with the cover body up and down;
the communication port is arranged in the sealing ring, corresponds to the opening of the collecting pipe and is positioned above the opposite port;
the pressing mechanism is arranged above the sealing ring and provides pressing force for the sealing ring, so that the connection between the collecting pipe and the butt joint opening is kept tight.
Further optimizing the technical scheme, the pushing mechanism comprises a spring column and a sliding plate;
the spring column is fixed above the sealing ring;
the sliding plate is fixed above the spring column, and the upper surface of the sliding plate is attached to the inner wall of the cover body.
Further optimize this technical scheme, the middle part of suction tube is fixed with the sealing block, and the top of sealing block is connected with auxiliary spring, and the outside of sealing block is fixed with the link, and the sealing block is connected through link and sealing washer.
Further optimizing the technical scheme, the movable adjusting mechanism comprises a telescopic mechanism, a connecting pipe and a butt joint adsorption mechanism;
The telescopic mechanism is arranged below the suction pipe and is adapted to the up-and-down movement of the suction pipe;
The connecting pipe is arranged below the telescopic mechanism, and a rotary connection is formed between the connecting pipe and the shielding ring;
The butt joint adsorption mechanism is arranged at the end part of the connecting pipe and used for controlling the connection of the connecting pipe and the space below the collecting box.
Further optimizing the technical scheme, the telescopic mechanism comprises a connecting disc, a second telescopic tube and a movable rod;
the connecting disc is respectively fixed at the lower end of the suction pipe and the upper end of the connecting pipe;
The second telescopic pipe is arranged at the joint of the suction pipe and the connecting pipe and is used for communicating the suction pipe with the connecting pipe;
The movable rod penetrates through the connecting disc and forms an up-down sliding structure between the connecting discs.
Further optimizing the technical scheme, the butt joint adsorption mechanism comprises a fitting head, a first telescopic pipe, a reset spring and an attraction port;
the attaching head is arranged below the connecting pipe, is horizontally arranged, and the outer end of the attaching head is attached to the inner wall of the shielding ring;
the first telescopic pipe is arranged at the joint of the attaching head and the connecting pipe;
The reset spring is arranged on the outer side of the attaching head and provides thrust for the attaching head, so that the attaching head and the shielding ring are kept attached;
The suction port is formed in the bottom of the shielding ring, the suction port and the collecting box are correspondingly arranged, and the suction port and the attaching head form a communicating structure after being in butt joint.
Compared with the prior art, the invention has the beneficial effects that:
Connect through sealing washer and collecting pipe, collecting pipe cooperation intercommunication mouth and butt joint are inhaled the sample in collecting the box, and the sealing washer can keep inseparable laminating with the lid, the sealed effect of device when guaranteeing to inhale, follow-up sealing washer can upwards move and relieve the laminating and rotate and switch sample collection position, can also guarantee the sealed effect after the position adjustment when making the collecting pipe can adjust sample collection position, make the suction of device keep stable, avoid the suction extravagant.
Through hiding retaining ring and division board and dividing in with the casing in even space, after the use position of box is collected in follow-up switching, the collection box that does not use or the collection box of accomplishing the collection can take out in the casing alone, does not influence the use of other collection boxes, also can carry out the installation of new collection box, makes the device use more nimble.
The suction space of the suction pipe is reduced through the uniform distribution of the space in the shell, so that the suction force can be effectively utilized, the suction pipe can rotate when the position of the collection pipe is adjusted, the joint of the joint head and the suction port is synchronously adjusted, and samples are sucked into different collection boxes to be collected and separated.
The inside of casing is installed to the box that will collect through the rotation of mounting, and the sealed pad of cooperation after collecting the box installation can keep its sealed effect, and follow-up accessible mounting's rotation is taken out single box that collects and is carried out the processing of sample, increases the whole sealed effect of device.
The suction pipe can move upwards along with the sealing ring through the arrangement of the second telescopic pipe, the position of the connecting pipe is not affected during movement, and meanwhile, the rotary power of the suction pipe can be stably transmitted to the laminating head through the movable rod on the outer side of the second telescopic pipe, and the laminating head is driven to synchronously rotate so as to adjust the laminating position of the laminating head.
Drawings
Fig. 1 is a schematic perspective view of the present invention.
Fig. 2 is a schematic view showing the bottom structure of the cover body of the present invention.
Fig. 3 is a schematic view of a main sectional structure of a cover body of the present invention.
Fig. 4 is a schematic perspective view of a seal ring according to the present invention.
Fig. 5 is a schematic perspective view of the suction tube of the present invention.
Fig. 6 is a schematic top view of the present invention.
Fig. 7 is a schematic top view of the housing of the present invention.
Fig. 8 is a schematic perspective view of the housing of the present invention.
Fig. 9 is a schematic perspective view of the collecting box of the present invention.
Fig. 10 is a schematic view of the main sectional structure of the housing of the present invention.
1, A shell, 2, a cover body, 3, a collecting pipe, 4, a suction pipe, 5, a sealing ring, 6, a communication port, 7, a butt joint port, 8, a spring column, 9, a sliding plate, 10, a sealing block, 11, an auxiliary spring, 12, a connecting frame, 13, a connecting pipe, 14, a bonding head, 15, a first telescopic pipe, 16, a return spring, 17, a connecting disc, 18, a second telescopic pipe, 19, a movable rod, 20, a shielding ring, 21, a partition plate, 22, a collecting box, 23, a filter plate, 24, a suction port, 25, an installation piece, 26, an installation groove, 27 and a sealing gasket.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
The first embodiment of the invention provides a technical scheme that the tissue sample collecting and separating device comprises a shell 1 and a cover body 2, wherein the cover body 2 is detachably arranged above the shell 1, a collecting pipe 3 is arranged above the cover body 2, the collecting pipe 3 is connected with an endoscope suction cavity, a suction pipe 4 is arranged in the middle of the cover body 2, suction force is provided in the shell 1, a shielding ring 20 is fixed in the middle of the shell 1, a partition plate 21 is fixed on the outer side of the shielding ring 20, the partition plate 21 is matched with the shielding ring 20 to divide the shell 1 into uniform spaces, a collecting box 22 is arranged on the inner side of the partition plate 21, a filter plate 23 for separating samples is arranged inside the collecting box 22, a butt joint mechanism is arranged between the collecting box 22 and the shell 1, the collecting box 22 is connected with the shell 1 through the butt joint mechanism, a butt joint port 7 is arranged on the lower surface of the cover body 2, the butt joint port 7 is correspondingly provided with the collecting pipe 3, and a movable adjusting mechanism is connected below the suction pipe 4.
Can connect collecting pipe 3 and endoscope suction chamber when using, suction tube 4 and suction mechanism connect, make the collection box 22 below that corresponds produce negative pressure adsorption affinity, inhale the collection pipe 3 with the sample in, make the sample whereabouts to the surface of filter plate 23, filter the separation with the sample, liquid accessible suction tube 4 is discharged, the sample remains on the surface of filter plate 23, follow-up can take out collection box 22 from casing 1 in to handle the sample, and the space outside of single collection box 22 is independent relatively, the collection work of other collection boxes 22 is not influenced after single collection box 22 takes out.
On the basis of the first embodiment, as shown in fig. 8-10, it is further disclosed that the cover body 2 and the shell 1 form threaded connection, the outer side of the cover body 2 is of a regular polygon structure design, the rotation of the cover body 2 is controlled in an auxiliary mode, the docking mechanism comprises a mounting piece 25 and a mounting groove 26, the mounting piece 25 is arranged at the lower part of the collecting box 22, the front end and the rear end of the mounting piece 25 respectively penetrate through the front end and the rear end of the collecting box 22, the mounting piece 25 and the collecting box 22 form rotary connection, the mounting groove 26 is formed on the surface of the shielding ring 20, the mounting groove 26 and the mounting piece 25 form threaded connection, a sealing gasket 27 is arranged at the outer side of the collecting box 22, and the sealing gasket 27 seals a connection gap after the collecting box 22 and the shell 1 are connected.
The lid 2 accessible rotatory mode is connected and is dismantled with casing 1, when installing collecting box 22, can insert the inside of casing 1 with collecting box 22, makes mounting 25 and mounting groove 26 relative, then rotatory mounting 25 makes mounting 25 rotate in collecting box 22, carries out threaded connection between mounting 25 and the mounting groove 26 simultaneously, drives collecting box 22 horizontal migration, makes sealed pad 27 and casing 1 keep hugging closely, realizes the installation to collecting box 22, has guaranteed the sealed effect of installation department simultaneously, makes its suction keep stable.
Embodiment III: on the basis of the first embodiment, as shown in fig. 2-7, it is further disclosed that the sealing connection mechanism comprises a sealing ring 5, a communication port 6 and a pushing mechanism, the sealing ring 5 is fixed below the collecting pipe 3, the sealing ring 5 is of an annular structure design, the sealing ring 5 and the cover body 2 form an up-down movable connection, the communication port 6 is arranged inside the sealing ring 5, the communication port 6 and the opening of the collecting pipe 3 are correspondingly arranged, the communication port 6 is positioned above the butt joint 7, the pushing mechanism is arranged above the sealing ring 5 to provide pushing force for the sealing ring 5, so that the connection between the collecting pipe 3 and the butt joint 7 is kept tight, the pushing mechanism comprises a spring column 8 and a sliding plate 9, the spring column 8 is fixed above the sealing ring 5, the sliding plate 9 is fixed above the spring column 8, the upper surface of the sliding plate 9 is in fit with the inner wall of the cover body 2, the middle part of the suction pipe 4 is fixed with a sealing block 10, an auxiliary spring 11 is connected above the sealing block 10, the outer side of the sealing block 10 is fixed with a connecting frame 12, the sealing block 10 is connected with a sealing ring 5 through the connecting frame 12, a movable adjusting mechanism comprises a telescopic mechanism, a connecting pipe 13 and a butt joint adsorption mechanism, the telescopic mechanism is arranged below the suction pipe 4 and is adapted to move up and down of the suction pipe 4, the connecting pipe 13 is arranged below the telescopic mechanism, a rotary connection is formed between the connecting pipe 13 and a shielding ring 20, the butt joint adsorption mechanism is arranged at the end part of the connecting pipe 13 to control the connection of the connecting pipe 13 and a space below a collecting box 22, the telescopic mechanism comprises a connecting disc 17, a second telescopic pipe 18 and a movable rod 19, the connecting disc 17 is respectively fixed at the lower end of the suction pipe 4 and the upper end of the connecting pipe 13, the second telescopic pipe 18, the suction pipe 4 and the connecting pipe 13 are communicated at the joint of the suction pipe 4 and the connecting pipe 13, the movable rod 19 penetrates through the connecting disk 17 and the connecting disk 17 to form an up-down sliding structure, the butt joint adsorption mechanism comprises a joint head 14, a first telescopic pipe 15, a reset spring 16 and a suction port 24, the joint head 14 is arranged below the connecting pipe 13, the joint head 14 is horizontally arranged, the outer end of the joint head 14 is jointed with the inner wall of a shielding ring 20, the first telescopic pipe 15 is arranged at the joint of the joint head 14 and the connecting pipe 13, the reset spring 16 is arranged outside the joint head 14 to provide thrust for the joint head 14, the joint head 14 and the shielding ring 20 are kept in joint, the suction port 24 is arranged at the bottom of the shielding ring 20, the suction port 24 and the collecting box 22 are correspondingly arranged, and the joint between the suction port 24 and the joint head 14 forms a communication structure.
When the suction is carried out, the sealing ring 5 keeps sealing with the cover body 2 under the action of the downward pressure of the spring column 8, the suction pipe 4 keeps sealing through the sealing block 10 and the cover body 2, the suction force is stably transmitted, when the use of the collecting box 22 needs to be switched, the suction pipe 4 can be pulled upwards, the sealing block 10 is driven to move upwards by the suction pipe 4, the sealing block 10 drives the sealing ring 5 to move upwards through the connecting frame 12, meanwhile, the suction pipe 4 is pulled to move by the second telescopic pipe 18, then the suction pipe 4 is rotated, the sealing ring 5 and the collecting pipe 3 are synchronously driven to rotate, the suction pipe 4 is adjusted to the upper part of other collecting boxes 22, the communicating port 6 corresponds to the butt joint 7, meanwhile, the connecting pipe 13 and the joint head 14 are driven to rotate through the movable rod 19, the same sliding structure as the movable rod 19 can be arranged between the joint head 14 and the connecting pipe 13, the joint head 14 is more stable in moving, the butt joint positions of the joint head 14 and the suction port 24 are switched after the joint head 14 moves, accordingly suction control is provided for the collecting box 22 at different positions, the suction pipe 4 is loosened after adjustment, the auxiliary spring 11 and the spring column 8 push the sealing block 10 and the sealing block 5 downwards, and the suction force is kept stable, and the suction force is prevented from being wasted after the suction is continuously sealed.
What is not described in detail in this specification is prior art known to those skilled in the art.
In the description of the present application, unless explicitly stated or limited otherwise, the term "disposed," "mounted," and the like are to be construed broadly, and may be fixedly connected, detachably connected, or integrally connected, mechanically connected, electrically connected, or indirectly connected via an intermediate medium, for example. The specific meaning of the above terms in the present application will be understood in specific cases by those of ordinary skill in the art.
Although the present invention has been described with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments described, or equivalents may be substituted for elements thereof, and any modifications, equivalents, improvements and changes may be made without departing from the spirit and principles of the present invention.