CN116549873A - A carrier delivery system for loadable particles - Google Patents
A carrier delivery system for loadable particles Download PDFInfo
- Publication number
- CN116549873A CN116549873A CN202310593892.XA CN202310593892A CN116549873A CN 116549873 A CN116549873 A CN 116549873A CN 202310593892 A CN202310593892 A CN 202310593892A CN 116549873 A CN116549873 A CN 116549873A
- Authority
- CN
- China
- Prior art keywords
- tube
- stent
- particle
- locking
- outer tube
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002245 particle Substances 0.000 title claims abstract description 93
- 238000011084 recovery Methods 0.000 claims abstract description 67
- 238000000034 method Methods 0.000 claims description 25
- 230000008569 process Effects 0.000 claims description 19
- 230000006835 compression Effects 0.000 claims description 16
- 238000007906 compression Methods 0.000 claims description 16
- 238000001125 extrusion Methods 0.000 claims description 9
- 230000002093 peripheral effect Effects 0.000 claims description 6
- 230000007704 transition Effects 0.000 claims description 3
- 230000002285 radioactive effect Effects 0.000 description 11
- 230000005855 radiation Effects 0.000 description 4
- 238000010586 diagram Methods 0.000 description 3
- 238000002513 implantation Methods 0.000 description 3
- 238000004873 anchoring Methods 0.000 description 2
- 230000003902 lesion Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 206010073306 Exposure to radiation Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 208000031481 Pathologic Constriction Diseases 0.000 description 1
- 230000004308 accommodation Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000003445 biliary tract Anatomy 0.000 description 1
- 210000000621 bronchi Anatomy 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000003238 esophagus Anatomy 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 239000002861 polymer material Substances 0.000 description 1
- 210000003240 portal vein Anatomy 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 238000004064 recycling Methods 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 210000003437 trachea Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1002—Intraluminal radiation therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2/9522—Means for mounting a stent or stent-graft onto or into a placement instrument
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2/962—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve
- A61F2/966—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1007—Arrangements or means for the introduction of sources into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1014—Intracavitary radiation therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2002/9528—Instruments specially adapted for placement or removal of stents or stent-grafts for retrieval of stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1007—Arrangements or means for the introduction of sources into the body
- A61N2005/1008—Apparatus for temporary insertion of sources, e.g. afterloaders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1007—Arrangements or means for the introduction of sources into the body
- A61N2005/1009—Apparatus for loading seeds into magazines or needles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1007—Arrangements or means for the introduction of sources into the body
- A61N2005/101—Magazines or cartridges for seeds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N2005/1092—Details
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Pathology (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
本发明公开了一种可载粒子支架输送系统。该系统包括内管与外管。外管包括近端端部开口、远端端部开口以及从其近端端部开口延伸出其远端端部开口的第一内腔。内管可滑动地套设在第一内腔内。内管的远端段与第一内腔侧壁之间形成有用于容纳收拢的可载粒子支架的支架容纳腔。该系统还包括锚定件和支架回收管;锚定件与内管固接且位于支架容纳腔内,用于在回收支架时与可载粒子支架相连接以及在释放支架时与可载粒子支架相脱离。支架回收管与外管远端可拆卸地连接且内部与外管的第一内腔连通。当外管朝向内管远端移动时,支架回收管朝向可载粒子支架处于膨胀状态的一端移动并使可载粒子支架中穿过支架回收管的对应段向内收拢后进入外管的第一内腔内。
The invention discloses a carrier delivery system for loadable particles. The system includes an inner tube and an outer tube. The outer tube includes a proximal end opening, a distal end opening, and a first lumen extending from its proximal end opening to its distal end opening. The inner tube is slidably sleeved in the first inner cavity. A stent accommodating cavity for accommodating the collapsed particle-loaded stent is formed between the distal end section of the inner tube and the side wall of the first lumen. The system also includes an anchor and a stent recovery tube; the anchor is fixedly connected to the inner tube and is located in the stent accommodating cavity, and is used for connecting with the particle-loaded stent when the stent is recovered and with the particle-loaded stent when the stent is released. Separated from each other. The stent recovery tube is detachably connected to the distal end of the outer tube and communicates with the first lumen of the outer tube inside. When the outer tube moves toward the distal end of the inner tube, the stent recovery tube moves towards the expanded end of the particle-loaded stent and draws the corresponding section of the particle-loaded stent that passes through the stent recovery tube inward and then enters the first section of the outer tube. Inside the lumen.
Description
技术领域technical field
本发明涉及医疗设备技术领域,具体涉及一种用于腔道内的可载粒子支架输送系统。The invention relates to the technical field of medical equipment, in particular to a particle-loadable stent delivery system used in a cavity.
背景技术Background technique
目前支架的应用范围很广泛,可用于治疗人体胆道、门静脉、气管、主支气管、食道、肠道以及各种器质性狭窄。现有技术通常采用手动挤压的方式将支架装载到输送器的置入管内,通过导丝、气管镜等将支架植入到病变位置后完成支架释放At present, stents have a wide range of applications and can be used to treat human biliary tract, portal vein, trachea, main bronchi, esophagus, intestinal tract and various organic strictures. In the prior art, the stent is usually loaded into the insertion tube of the conveyor by manual extrusion, and the stent is implanted into the lesion through a guide wire, bronchoscope, etc. to complete the release of the stent
对于腔道内的实体肿瘤,将I-125放射性粒子和可载粒子支架结合的方式是一种新型治疗方式。这种植入手术过程中需根据TPS系统计算需要的剂量,根据需要的剂量将粒子装填装入释放后的可载粒子支架上,再将装填完粒子后的可载粒子支架回收到输送器内等待术中使用。待上述步骤均在医院手术室内完成。For solid tumors in the cavity, the combination of I-125 radioactive particles and particle-loaded scaffolds is a new treatment method. During this implantation operation, the required dose needs to be calculated according to the TPS system, and the particles are loaded into the released particle-loaded stent according to the required dose, and then the loaded particle-loaded stent is recovered into the conveyor for waiting. Used intraoperatively. All the above steps are completed in the operating room of the hospital.
传统的可载粒子支架输送器不具备回收功能,而在装填完粒子之后,处于释放状态下的可载粒子支架很粗很难装入置入器内。并且,I-125放射性粒子具有一定的辐射性,手术医生以手动挤压的方式将支架回收入输送器的过程面临被辐射的风险。The traditional loadable particle rack conveyor does not have the function of recycling, and after the particles are loaded, the loaded particle rack in the released state is very thick and difficult to fit into the inserter. Moreover, the I-125 radioactive particles have certain radiation properties, and the surgeon faces the risk of being irradiated during the process of manually squeezing the stent back into the transporter.
发明内容Contents of the invention
发明目的:本发明所要解决的技术问题是针对现有技术的不足,提供一种可载粒子支架输送系统,便于回收与释放支架。Purpose of the invention: The technical problem to be solved by the present invention is to provide a particle-carrying stent delivery system for the deficiencies of the prior art, which facilitates recovery and release of the stent.
为了解决上述技术问题,本发明公开了一种可载粒子支架输送系统。该输送系统包括内管与外管。所述外管包括近端端部开口、远端端部开口以及从其近端端部开口延伸出其远端端部开口的第一内腔。所述内管可滑动地套设在外管的第一内腔内。所述内管的远端段与所述外管的第一内腔侧壁之间形成有用于容纳处于收拢状态的可载粒子支架的支架容纳腔。该系统还包括锚定件和支架回收管,所述锚定件与所述内管固接且位于所述支架容纳腔内,所述锚定件用于在回收过程时与所述可载粒子支架的近端相连接以及在释放过程时与所述可载粒子支架的近端相脱离。支架回收管可拆卸地连接于外管的远端且内部与外管的第一内腔连通。当所述外管朝向所述内管的远端移动,所述支架回收管朝向所述可载粒子支架处于膨胀状态的一端移动并使可载粒子支架中穿过所述支架回收管的对应段向内收拢后进入所述外管的第一内腔内。In order to solve the above-mentioned technical problems, the present invention discloses a particle-loadable stent delivery system. The delivery system includes an inner tube and an outer tube. The outer tube includes a proximal end opening, a distal end opening, and a first lumen extending from its proximal end opening to its distal end opening. The inner tube is slidably sleeved in the first lumen of the outer tube. A stent accommodating cavity for accommodating a particle-loaded stent in a collapsed state is formed between the distal end section of the inner tube and the first lumen side wall of the outer tube. The system also includes an anchor and a stent recovery tube, the anchor is affixed to the inner tube and located in the stent accommodating cavity, the anchor is used to interact with the loadable particles during the recovery process The proximal end of the stent is connected to and detached from the proximal end of the particle-laden stent during the release process. The stent recovery tube is detachably connected to the distal end of the outer tube and internally communicates with the first lumen of the outer tube. When the outer tube moves toward the distal end of the inner tube, the stent recovery tube moves toward the expanded end of the particle-laden stent and passes through the corresponding section of the particle-loaded stent through the stent recovery tube. After being folded inward, it enters the first inner cavity of the outer tube.
具体的,所述锚定件包括套环和若干锚定柱,所述套环固定套设于所述内管上,所述锚定柱沿所述套环的周向间隔设置于所述套环的近端外周。所述套环中位于相邻两个锚定柱之间的外周侧壁向内凹陷形成有凹槽,所述凹槽沿套环轴向贯通,用于容纳处于收拢状态的可载粒子支架近端的编织丝。Specifically, the anchoring piece includes a collar and a plurality of anchor posts, the collar is fixedly sleeved on the inner tube, and the anchor posts are arranged on the sleeve at intervals along the circumferential direction of the collar. the proximal periphery of the ring. In the collar, the outer peripheral side wall located between two adjacent anchor columns is inwardly recessed to form a groove, and the groove penetrates through the collar axially, and is used for accommodating the particle-laden stent in a collapsed state. end of braided wire.
具体的,所述支架回收管为弹性套管结构,包括喇叭状压缩段、与所述喇叭状压缩段的小口端连接且与所述喇叭状压缩段内部连通的环状回收段以及贯穿所述支架回收管的侧壁的开缝。所述环状回收段穿入所述外管的远端端部开口与所述外管套接,所述环状回收段与所述外管的连接处平滑过渡。Specifically, the stent recovery tube is an elastic sleeve structure, including a horn-shaped compression section, an annular recovery section connected to the small mouth end of the horn-shaped compression section and communicating with the inside of the horn-shaped compression section, and passing through the Slits in the side walls of the bracket recovery tube. The annular recovering section penetrates into the distal end opening of the outer tube and is socketed with the outer tube, and the joint between the annular recovering section and the outer tube transitions smoothly.
具体的,该系统包括固接于所述内管远端端部的导向头和固定套接于所述内管外部的显影环,所述导向头、所述内管、所述显影环以及所述外管的第一内腔侧壁围合形成所述支架容纳腔。Specifically, the system includes a guide head fixed to the distal end of the inner tube and a developing ring fixedly sleeved outside the inner tube, the guide head, the inner tube, the developing ring and the The side wall of the first lumen of the outer tube surrounds and forms the stent accommodating cavity.
进一步的,还包括中管和中管固定手柄,所述中管套设于所述外管和所述内管之间。所述中管的远端端部与所述显影环固接,近端端部与所述中管固定手柄固接。Further, it also includes a middle pipe and a middle pipe fixing handle, and the middle pipe is sheathed between the outer pipe and the inner pipe. The distal end of the middle tube is fixedly connected to the developing ring, and the proximal end is fixedly connected to the fixing handle of the middle tube.
进一步的,还包括助推管和内管固定手柄,所述助推管套设于所述中管与所述内管之间。所述助推管的远端延伸至所述外管之内。Further, it also includes a booster tube and an inner tube fixing handle, the booster tube is sheathed between the middle tube and the inner tube. The distal end of the booster tube extends into the outer tube.
具体的,还包括锁止装置,所述锁止装置位于所述外管的远端与所述内管的远端之间,用于限制所述内管与所述外管在轴向上的相对滑动。Specifically, it also includes a locking device, the locking device is located between the distal end of the outer tube and the distal end of the inner tube, and is used to limit the axial distance between the inner tube and the outer tube. relatively sliding.
具体的,所述锁止装置包括第一锁紧连接件和第二锁紧连接件,所述第一锁紧连接件与所述外管的近端固接,所述内管的远端依次贯穿所述第二锁紧连接件、所述第一锁紧连接件后伸入所述外管的第一内腔内。所述第二锁紧连接件可旋转地套设于所述内管的外部。所述第一锁紧连接件沿径向依次包括锁紧部和第一螺纹连接部,所述第二锁紧连接件包括与所述锁紧部相配合的挤压部和与所述第一螺纹连接部相配合的第二螺纹连接部,所述第二锁紧连接件与所述第一锁紧连接件通过第一螺纹连接部与第二螺纹连接部旋接,所述挤压部用于在旋紧连接的过程中挤压所述锁紧部向内收拢抱紧所述内管。Specifically, the locking device includes a first locking connector and a second locking connector, the first locking connector is affixed to the proximal end of the outer tube, and the distal end of the inner tube is sequentially After penetrating through the second locking connector and the first locking connector, it extends into the first lumen of the outer tube. The second locking connector is rotatably sleeved on the outside of the inner tube. The first locking connection piece includes a locking portion and a first threaded connection portion sequentially in the radial direction, and the second locking connection piece includes an extruding portion matched with the locking portion and a The second threaded connection part matched with the threaded connection part, the second locking connection part is screwed with the first locking connection part through the first threaded connection part and the second threaded connection part, and the extruding part is used In the process of tightening the connection, the locking part is squeezed inwards to gather and hold the inner tube tightly.
具体的,所述第一锁紧连接件包括活动手柄以及锁紧卡箍,所述锁紧卡箍与所述活动手柄固接,以实现所述第一锁紧连接件与所述外管固接。所述锁紧部为所述锁紧卡箍的近端段,所述第一螺纹连接部为设置于所述活动手柄近端的内螺纹段。所述第二锁紧连接件为锁紧卡套,所述第二螺纹连接部为设置于所述锁紧卡套远端的外螺纹段,所述挤压部为设置于所述锁紧卡套的远端内周侧壁上且朝向近端向内倾斜设置的倾斜面,在旋接的过程中,所述倾斜面抵压所述锁紧卡箍的近端向内收拢抱紧所述内管。Specifically, the first locking connector includes a movable handle and a locking clip, and the locking clip is affixed to the movable handle so as to realize the fastening of the first locking connector to the outer tube. catch. The locking part is a proximal section of the locking clip, and the first threaded connection part is an internal thread section provided at the proximal end of the movable handle. The second locking connector is a locking ferrule, the second threaded connection part is an external thread section arranged at the distal end of the locking ferrule, and the extruding part is arranged on the locking ferrule The inclined surface on the inner peripheral side wall of the distal end of the sleeve and inclined inward toward the proximal end, during the screwing process, the inclined surface presses against the proximal end of the locking clip and draws inward to tightly hold the inner tube.
具体的,所述导向头开设有导引孔。所述内管包括近端端部开口、远端端部开口以及从其近端端部开口延伸出至其远端端部开口的第二内腔。所述导向头的导引孔与所述第二内腔相连通形成导丝通道。Specifically, the guide head is provided with a guide hole. The inner tube includes a proximal end opening, a distal end opening, and a second lumen extending from its proximal end opening to its distal end opening. The guide hole of the guide head communicates with the second inner cavity to form a guide wire channel.
有益效果:Beneficial effect:
(1)本申请提供的一种可载粒子支架输送系统,通过设置锚定件和支架回收管,所述锚定件与所述内管固接且位于所述支架容纳腔内,所述可载粒子支架与所述锚定件可拆卸的连接且内部与所述外管的远端端部开口相连通。在回收支架过程,当所述外管朝向所述内管的远端移动时,外管带动支架回收管朝向可载粒子支架处于膨胀状态的一端移动,并且支架回收管引导可载粒子支架中穿过支架回收管的对应段向内收拢后进入外管的第一内腔内。当外管相对于内管向远端移动一定行程后,可载粒子支架可完全收拢并回收于支架容纳腔内。在将支架释放至体内过程中,当外管朝向内管的近端移动一定行程后,可载粒子支架可完全自然释放并与所述锚定件相脱离。由此,本申请提供的一种可载粒子支架输送系统实现了释放和回收支架的功能。(1) In the particle-loaded stent delivery system provided by the present application, by setting an anchor piece and a stent recovery tube, the anchor piece is fixedly connected to the inner tube and is located in the stent accommodating cavity, and the can The particle-loaded stent is detachably connected to the anchor and communicates internally with the distal end opening of the outer tube. In the process of recovering the stent, when the outer tube moves toward the distal end of the inner tube, the outer tube drives the stent recovery tube to move towards the expanded end of the particle-loaded stent, and the stent recovery tube guides the particle-loaded stent through the The corresponding section of the stent recovery tube is folded inward and enters the first lumen of the outer tube. After the outer tube moves far to a certain distance relative to the inner tube, the particle-laden stent can be completely folded and recovered in the stent accommodating cavity. During the process of releasing the stent into the body, when the outer tube moves toward the proximal end of the inner tube for a certain distance, the particle-loaded stent can be completely and naturally released and separated from the anchor. Thus, the particle-loaded stent delivery system provided by the present application realizes the functions of releasing and recovering the stent.
(2)相比于现有技术中将装载有粒子的支架以手动挤压的方式逐段地收拢推入支架容纳腔内,本申请采用锚定件挂住可载粒子支架的近端并使这一段处于收拢状态,当外管朝向内管的远端移动时,支架回收管朝向可载粒子支架处于膨胀状态的一端移动,可载粒子支架中穿过支架回收管的对应段在支架回收管引导下向内连续地、平滑的收拢,该回收可载粒子支架的过程更便捷快速,能够提高手术的效率,节约手术时间。同时由于回收过程中,操作者无需以手动挤压的方式逐段地收拢可载粒子支架,因此本申请有助于降低放射性粒子对操作者的辐射风险。(2) Compared with the prior art where the stent loaded with particles is folded and pushed into the stent accommodating cavity segment by segment by manual extrusion, the present application uses anchors to hang the proximal end of the particle-loaded stent and make it This section is in a folded state. When the outer tube moves towards the distal end of the inner tube, the stent recovery tube moves towards the expanded end of the particle-loaded stent. Under the guidance, it is continuously and smoothly folded inward, and the process of recovering the particle-loaded stent is more convenient and faster, which can improve the efficiency of the operation and save the operation time. At the same time, since the operator does not need to manually squeeze the particle-carrying bracket section by section during the recovery process, the application helps to reduce the radiation risk of radioactive particles to the operator.
(3)本申请的一个实施例采用的支架回收管包括喇叭状压缩段、与喇叭状压缩段小口端连接且与喇叭状压缩段内部连通的环状回收段以及贯穿支架回收管的侧壁的开缝。由于喇叭状压缩段的内径逐渐减小,因此对可载粒子支架中穿过支架回收管的对应段起到向内收拢的导向作用,使得可载粒子支架中穿过支架回收管的对应段在喇叭状压缩段引导下向内连续地、平滑的收拢。通过在喇叭状压缩段的小口段设置环状回收段以及设置贯穿支架回收管的侧壁的开缝,使支架回收管形成弹性套管结构,将环状回收段从外管的远端端部开口插入外管内,环状回收段与外管形成紧压接触连接。这种可拆卸的连接方式结构简单、便于操作。(3) The bracket recovery tube used in one embodiment of the present application includes a horn-shaped compression section, an annular recovery section connected to the small mouth end of the horn-shaped compression section and communicated with the inside of the horn-shaped compression section, and a wall that runs through the side wall of the bracket recovery tube. Slit. Since the inner diameter of the trumpet-shaped compression section gradually decreases, it guides the corresponding section of the loadable particle stent passing through the stent recovery tube inwardly, so that the corresponding section of the loadable particle stent passing through the stent recovery tube is Under the guidance of the trumpet-shaped compression section, it gathers inward continuously and smoothly. By setting the annular recovery section at the small mouth section of the horn-shaped compression section and setting the slit through the side wall of the bracket recovery tube, the bracket recovery tube forms an elastic sleeve structure, and the annular recovery section is separated from the distal end of the outer tube. The opening is inserted into the outer tube, and the annular recovery section forms a tight contact connection with the outer tube. This detachable connection method is simple in structure and easy to operate.
(4)本申请既适用于载有放射性粒子的支架也适用于普通不带粒子自膨式支架。(4) This application is applicable to both stents loaded with radioactive particles and common self-expandable stents without particles.
附图说明Description of drawings
下面结合附图和具体实施方式对本发明做更进一步的具体说明,本发明的上述和/或其他方面的优点将会变得更加清楚。The advantages of the above and/or other aspects of the present invention will become clearer as the present invention will be further described in detail in conjunction with the accompanying drawings and specific embodiments.
图1是本发明的一个实施例提供的一种可载粒子支架输送系统的外部结构示意图;Fig. 1 is a schematic diagram of the external structure of a particle-loadable stent delivery system provided by an embodiment of the present invention;
图2是沿图1中的A-A线的剖视图;Fig. 2 is a sectional view along the line A-A in Fig. 1;
图3是图2所示B区域的局部放大图;Fig. 3 is a partial enlarged view of area B shown in Fig. 2;
图4是本发明的一个实施例提供的可载粒子支架处于膨胀状态的结构示意图;Fig. 4 is a schematic structural view of a particle-loaded stent in an expanded state provided by an embodiment of the present invention;
图5是本发明的一个实施例提供的可载粒子支架锚定于一种可载粒子支架输送系统的结构示意图;Fig. 5 is a schematic structural view of a particle-loaded stent anchored in a particle-loaded stent delivery system according to an embodiment of the present invention;
图6是沿图5中的D-D线的剖视图;Fig. 6 is a sectional view along the line D-D in Fig. 5;
图7是图5所示E区域的局部放大图;Fig. 7 is a partial enlarged view of the E region shown in Fig. 5;
图8是本发明的一个实施例提供的可载粒子支架完全收拢于一种可载粒子支架输送系统内的结构示意图;Fig. 8 is a schematic structural view of a particle-loadable stent completely folded in a particle-loadable stent delivery system according to an embodiment of the present invention;
图9是图8所示F区域的局部放大图;Fig. 9 is a partial enlarged view of the F area shown in Fig. 8;
图10是本发明的一个实施例提供的锚定件的结构示意图;Fig. 10 is a schematic structural diagram of an anchor provided by an embodiment of the present invention;
图11是本发明的一个实施例提供的可载粒子支架锚定于图10所示的锚定件的结构示意图;Fig. 11 is a schematic structural view of a particle-loaded scaffold anchored to the anchor shown in Fig. 10 according to an embodiment of the present invention;
图12是本发明的一个实施例提供的支架回收管的结构示意图;Fig. 12 is a schematic structural view of a stent recovery tube provided by an embodiment of the present invention;
图13是图1所示C区域的局部放大图;Fig. 13 is a partial enlarged view of area C shown in Fig. 1;
图14是本发明提供的一种实施例的向图5所示的可载粒子支架进行放射性粒子装填的示意图。Fig. 14 is a schematic diagram of loading radioactive particles into the particle-loadable rack shown in Fig. 5 according to an embodiment of the present invention.
附图标记如下所示:输送系统100、内管101、外管102、近端端部开口103、远端端部开口104、第一内腔105、支架容纳腔106、锚定件107、支架回收管108、套环109、锚定柱110、凹槽111、导向头112、显影环113、中管114、中管固定手柄115、助推管116、内管固定手柄117、锁止装置118、第一锁紧连接件119、第二锁紧连接件120、锁紧部121、第一螺纹连接部122、挤压部123、第二螺纹连接部124、活动手柄125、锁紧卡箍126、导引孔127、第二内腔128、喇叭状压缩段129、环状回收段130、开缝131、可载粒子支架200、粒子植入器300。Reference numerals are as follows: delivery system 100, inner tube 101, outer tube 102, proximal end opening 103, distal end opening 104, first lumen 105, stent receiving lumen 106, anchor 107, stent Recovery tube 108, collar 109, anchor post 110, groove 111, guide head 112, developing ring 113, middle tube 114, middle tube fixing handle 115, booster tube 116, inner tube fixing handle 117, locking device 118 , the first locking connection part 119, the second locking connection part 120, the locking part 121, the first threaded connection part 122, the extrusion part 123, the second threaded connection part 124, the movable handle 125, the locking clip 126 , the guide hole 127, the second inner cavity 128, the trumpet-shaped compression section 129, the annular recovery section 130, the slot 131, the particle-carrying bracket 200, and the particle implanter 300.
具体实施方式Detailed ways
下面结合附图对本申请的技术方案进行详尽的描述。The technical solution of the present application will be described in detail below in conjunction with the accompanying drawings.
如图1和图2所示,本申请提供了一种可载粒子支架输送系统,用于回收和植入可载粒子支架200。可载粒子支架200具有自膨胀的特性,可通过外部压握至收拢状态,解除外部作用力后则自扩张释放。该输送系统100包括内管101与外管102。所述外管102包括近端端部开口103、远端端部开口104以及从其近端端部开口103延伸出其远端端部开口104的第一内腔105。如图2和图3所示,所述内管101可滑动地套设在外管102的第一内腔105内。所述内管101的远端段与所述外管102的第一内腔105侧壁之间形成有用于容纳处于收拢状态的可载粒子支架200的支架容纳腔106。具体的,如图3所示,该系统包括固接于所述内管101远端端部的导向头112和固定套接于所述内管101外部的显影环113,所述导向头112、所述内管101、所述显影环113以及所述外管102的第一内腔105侧壁围合形成所述支架容纳腔106。As shown in FIG. 1 and FIG. 2 , the present application provides a particle-loaded stent delivery system for recovering and implanting a particle-loaded stent 200 . The particle-loaded stent 200 has the property of self-expansion, and can be squeezed to a collapsed state by external pressure, and then self-expanded and released after the external force is removed. The delivery system 100 includes an inner tube 101 and an outer tube 102 . The outer tube 102 includes a proximal end opening 103 , a distal end opening 104 and a first lumen 105 extending from its proximal end opening 103 and its distal end opening 104 . As shown in FIGS. 2 and 3 , the inner tube 101 is slidably sleeved in the first lumen 105 of the outer tube 102 . A stent accommodating cavity 106 for accommodating the particle-loaded stent 200 in a collapsed state is formed between the distal section of the inner tube 101 and the side wall of the first inner cavity 105 of the outer tube 102 . Specifically, as shown in FIG. 3 , the system includes a guide head 112 affixed to the distal end of the inner tube 101 and a developing ring 113 fixedly sleeved on the outside of the inner tube 101. The guide head 112, The inner tube 101 , the developing ring 113 , and the sidewall of the first inner cavity 105 of the outer tube 102 enclose the bracket receiving cavity 106 .
如图4所示,现有技术中,在可载粒子支架200处于膨胀状态下时对其进行装填。在植入手术前和手术过程中,操作者均需要通过手动挤压的方式使装载有放射性粒子的支架逐段地收拢推入支架容纳腔106内。这种方式既存在辐射风险,效率也很低,进而导致术中时间延长。As shown in FIG. 4 , in the prior art, the particle-loaded scaffold 200 is loaded when it is in an expanded state. Before and during the implantation operation, the operator needs to push the stent loaded with radioactive particles into the stent accommodating cavity 106 segment by segment by manually squeezing. This method not only has radiation risks, but also has low efficiency, which leads to prolonged intraoperative time.
为了便于向支架容纳腔106内回收可载粒子支架200,如图5和图6所示,该系统还包括锚定件107和支架回收管108,所述锚定件107与所述内管101固接且位于所述支架容纳腔106内,所述锚定件107用于在回收过程时与所述可载粒子支架200的近端相连接,在释放过程时与所述可载粒子支架200的近端相脱离。如图7所示,所述支架回收管108的内径逐渐变小,使用时,所述支架回收管108套设于所述内管101的外侧,所述支架回收管108的小径端与所述外管102的远端可拆卸地连接且所述支架回收管108的内部与所述外管102的第一内腔105连通。In order to facilitate recovery of the particle-loaded stent 200 into the stent accommodating chamber 106, as shown in Figure 5 and Figure 6, the system also includes an anchor 107 and a stent recovery tube 108, the anchor 107 is connected to the inner tube 101 Fixed and located in the stent containing cavity 106, the anchor 107 is used to connect with the proximal end of the particle-loaded stent 200 during the recovery process, and connect with the particle-loaded stent 200 during the release process. The proximal phase is detached. As shown in Figure 7, the inner diameter of the stent recovery tube 108 gradually becomes smaller. When in use, the stent recovery tube 108 is sleeved on the outside of the inner tube 101, and the small-diameter end of the stent recovery tube 108 is in contact with the The distal end of the outer tube 102 is detachably connected and the inside of the stent recovery tube 108 communicates with the first lumen 105 of the outer tube 102 .
使用本申请提供的一种可载粒子支架输送系统回收和释放支架的工作过程如下:The working process of recovering and releasing the stent using a particle-loaded stent delivery system provided by the present application is as follows:
回收支架前,将支架回收管安装于外管的远端,并使所述外管102的远端端部位于所述内管101的远端端部的近端以使所述支架容纳腔106呈开放状态。待回收的处于膨胀状态的可载粒子支架200套设于所述支架容纳腔106的外侧,并且其近端向内收拢后锚定于所述锚定件107,从而使所述可载粒子支架200的近端与所述内管101处于连接状态。Before recovering the stent, the stent recovery tube is installed on the distal end of the outer tube, and the distal end of the outer tube 102 is positioned at the proximal end of the distal end of the inner tube 101 so that the stent receiving chamber 106 is open. The particle-loaded stent 200 to be recovered in an expanded state is sheathed on the outside of the stent-accommodating cavity 106, and its proximal end is drawn inward and then anchored to the anchor 107, so that the particle-loaded stent The proximal end of 200 is connected to the inner tube 101 .
回收支架时,当所述外管102相对于所述内管101向远端移动,所述支架回收管108朝向所述可载粒子支架200处于膨胀状态的一端移动并使可载粒子支架200中穿过所述支架回收管108的对应部分向内收拢后进入所述外管102的第一内腔105内。当所述外管102相对于所述内管101向远端移动一定行程后,所述可载粒子支架200可完全收拢并回收于所述支架容纳腔106内,如图8和图9所示。回收支架后、向体内植入支架前可将支架回收器从该输送系统上拆除。When recovering the stent, when the outer tube 102 moves to the distal end relative to the inner tube 101, the stent recovery tube 108 moves toward the expanded end of the particle-loaded stent 200 and makes the particle-loaded stent 200 The corresponding part passing through the stent recovery tube 108 is folded inward and enters the first inner cavity 105 of the outer tube 102 . After the outer tube 102 moves to the distal end relative to the inner tube 101 for a certain distance, the particle-loaded stent 200 can be completely folded and recovered in the stent accommodation chamber 106, as shown in FIGS. 8 and 9 . After the stent is retrieved, the stent retriever can be removed from the delivery system before implanting the stent into the body.
释放支架时,当所述外管102朝向所述内管101的近端移动时至所述支架容纳腔106呈开放状态时,所述可载粒子支架200自然膨胀并与所述锚定件107相脱离。When the stent is released, when the outer tube 102 moves toward the proximal end of the inner tube 101 until the stent accommodating cavity 106 is in an open state, the particle-loaded stent 200 naturally expands and connects with the anchor 107 Separated from each other.
具体的,如图10所示,所述锚定件107包括套环109和若干锚定柱110。所述套环109固定套设于所述内管101上。所述锚定柱110沿所述套环109的周向间隔设置于所述套环109的近端外周。所述套环109中位于相邻两个锚定柱110之间的外周侧壁向内凹陷形成有凹槽111,所述凹槽111沿套环109轴向贯通。如图11所示,回收支架时,所述可载粒子支架200的近端编织丝挂设在锚定柱110上并且处于收拢状态的所述可载粒子支架200的近端编织丝位于对应的凹槽111中。Specifically, as shown in FIG. 10 , the anchor 107 includes a collar 109 and several anchor posts 110 . The collar 109 is fixedly sleeved on the inner tube 101 . The anchor posts 110 are disposed on the outer periphery of the proximal end of the collar 109 at intervals along the circumferential direction of the collar 109 . A groove 111 is formed on the outer peripheral sidewall of the collar 109 between two adjacent anchor posts 110 , and the groove 111 penetrates through the collar 109 in the axial direction. As shown in FIG. 11 , when recovering the stent, the proximal braided wire of the particle-loaded stent 200 is hung on the anchor post 110 and the proximal braided wire of the particle-loaded stent 200 in the collapsed state is located at the corresponding In the groove 111.
具体的,如图12所示,所述支架回收管108为弹性套管结构,可以采用例如PP、PET等塑料材料制成,也可以采用不锈钢材料制成。所述支架回收管108包括喇叭状压缩段129、与所述喇叭状压缩段129小口端连接且与所述喇叭状压缩段129内部连通的环状回收段130以及贯穿所述支架回收管108的侧壁的开缝131。所述环状回收段130穿入所述外管102的远端端部开口与所述外管102套接,所述环状回收段130与所述外管102的连接处平滑过渡。Specifically, as shown in FIG. 12 , the bracket recovery pipe 108 is an elastic sleeve structure, which can be made of plastic materials such as PP, PET, or stainless steel. The stent recovery pipe 108 includes a horn-shaped compression section 129, an annular recovery section 130 connected to the small mouth end of the horn-shaped compression section 129 and communicated with the inside of the horn-shaped compression section 129, and a ring that runs through the stent recovery tube 108. The slit 131 of the side wall. The annular recovery section 130 penetrates into the distal end opening of the outer tube 102 and is socketed with the outer tube 102 , and the connection between the annular recovery section 130 and the outer tube 102 transitions smoothly.
如图2所示,所述导向头112与所述内管101连接并形成有导丝通道。导丝穿过导丝通道引导输送器至病灶部位。As shown in FIG. 2 , the guide head 112 is connected to the inner tube 101 and forms a guide wire channel. A guide wire is passed through the guide wire channel to guide the conveyor to the lesion site.
具体的,导向头11由具有弹性体功能的高分子材料制成,整体呈锥形设置。所述导向头112开设有导引孔127。所述内管101包括近端端部开口103、远端端部开口104以及从其近端端部开口103延伸出至其远端端部开口104的第二内腔128。所述导引孔127与所述第二内腔128相连通形成导丝通道。Specifically, the guide head 11 is made of a polymer material with an elastic body function, and is arranged in a tapered shape as a whole. The guide head 112 defines a guide hole 127 . The inner tube 101 includes a proximal end opening 103 , a distal end opening 104 and a second lumen 128 extending from its proximal end opening 103 to its distal end opening 104 . The guide hole 127 communicates with the second lumen 128 to form a guide wire channel.
如图2所示,该系统还包括中管114和中管固定手柄115,所述中管114套设于所述外管102和所述内管101之间,起到支撑外管102和提高输送器过弯性的作用。所述中管114的远端端部与所述显影环113固接,近端端部与所述中管固定手柄115固接。As shown in Figure 2, the system also includes a middle tube 114 and a fixed handle 115 for the middle tube. The middle tube 114 is sleeved between the outer tube 102 and the inner tube 101 to support the outer tube 102 and raise the The effect of conveyor bending. The distal end of the middle tube 114 is fixedly connected to the developing ring 113 , and the proximal end is fixedly connected to the middle tube fixing handle 115 .
如图2所示,该系统还包括助推管116和内管固定手柄117,所述助推管116套设于所述中管114与所述内管101之间,起到增加推送端强度的作用。所述助推管116的远端延伸至所述外管102之内。As shown in Figure 2, the system also includes a booster tube 116 and an inner tube fixing handle 117, the booster tube 116 is sleeved between the middle tube 114 and the inner tube 101 to increase the strength of the pushing end role. The distal end of the booster tube 116 extends into the outer tube 102 .
如图13所示,为了在向可载粒子支架装填放射性粒子的过程以及将输送系统植入体内的过程中,该系统还包括锁止装置118,所述锁止装置118位于所述外管102的远端与所述内管101的远端之间,用于限制所述内管101与所述外管102在轴向上的相对滑动,以确保将输送系统导入体内的过程中可载粒子支架稳定地收容于所述支架容纳腔106内。在一个实施例中,如图12所示,所述锁止装置118包括第一锁紧连接件119和第二锁紧连接件120,所述第一锁紧连接件119与所述外管102的近端固接,所述内管101的远端依次贯穿所述第二锁紧连接件120、所述第一锁紧连接件119后伸入所述外管102的第一内腔105内;所述第二锁紧连接件120可旋转地套设于所述内管101的外部;所述第一锁紧连接件119沿径向依次包括锁紧部121和第一螺纹连接部122,所述第二锁紧连接件120包括与所述锁紧部121相配合的挤压部123和与所述第一螺纹连接部122相配合的第二螺纹连接部124,所述第二锁紧连接件120与所述第一锁紧连接件119通过第一螺纹连接部122与第二螺纹连接部124旋接,所述挤压部123用于在旋紧连接的过程中挤压所述锁紧部121向内收拢抱紧所述内管101。在一个特定实施例中,如图13所示,所述第一锁紧连接件119包括活动手柄125以及锁紧卡箍126,所述锁紧卡箍126与所述活动手柄125固接,以实现所述第一锁紧连接件119与所述外管102固接;所述锁紧部121为所述锁紧卡箍126的近端段,所述第一螺纹连接部122为设置于所述活动手柄125近端的内螺纹段;所述第二锁紧连接件120为锁紧卡套,所述第二螺纹连接部124为设置于所述锁紧卡套远端的外螺纹段,所述挤压部123为设置于所述锁紧卡套的远端内周侧壁上且朝向近端向内倾斜设置的倾斜面,当所述锁紧卡套的远端插入所述空腔中并朝向远端旋转移动时,所述倾斜面抵压所述锁紧卡箍126的近端向内收拢抱紧所述内管101。As shown in FIG. 13 , in order to load the radioactive particles into the particle-loaded stent and implant the delivery system into the body, the system further includes a locking device 118 located on the outer tube 102 Between the distal end of the inner tube 101 and the distal end of the inner tube 101, it is used to limit the relative sliding between the inner tube 101 and the outer tube 102 in the axial direction, so as to ensure that the delivery system can carry particles during the process of introducing the delivery system into the body. The bracket is stably accommodated in the bracket receiving chamber 106 . In one embodiment, as shown in FIG. 12 , the locking device 118 includes a first locking connector 119 and a second locking connector 120 , the first locking connector 119 is connected to the outer tube 102 The proximal end of the inner tube 101 is affixed, and the distal end of the inner tube 101 passes through the second locking connector 120 and the first locking connector 119 in turn, and then extends into the first inner cavity 105 of the outer tube 102 The second locking connector 120 is rotatably sleeved on the outside of the inner tube 101; the first locking connector 119 sequentially includes a locking portion 121 and a first threaded connection portion 122 in the radial direction, The second locking connector 120 includes an extrusion part 123 matched with the locking part 121 and a second threaded part 124 matched with the first threaded part 122, the second locking The connecting piece 120 is screwed to the first locking connecting piece 119 through the first threaded connection part 122 and the second threaded connection part 124, and the extrusion part 123 is used to squeeze the lock during the screw connection process. The tight portion 121 is drawn inwards to hug the inner tube 101 tightly. In a specific embodiment, as shown in FIG. 13 , the first locking connector 119 includes a movable handle 125 and a locking clip 126, and the locking clip 126 is affixed to the movable handle 125, so as to Realize that the first locking connector 119 is firmly connected to the outer tube 102; the locking part 121 is the proximal end section of the locking clip 126, and the first threaded connection part 122 is arranged on the outer tube 102. The internal thread segment at the proximal end of the movable handle 125; the second locking connector 120 is a locking ferrule, and the second threaded connection part 124 is an external thread segment arranged at the far end of the locking ferrule, The extrusion part 123 is an inclined surface arranged on the inner peripheral side wall of the distal end of the locking ferrule and inclined inward toward the proximal end, when the distal end of the locking ferrule is inserted into the cavity When rotating and moving toward the distal end, the inclined surface presses against the proximal end of the locking clip 126 and draws inwards to hug the inner tube 101 tightly.
使用本申请的一种可载粒子支架输送系统回收和释放支架的过程如下:The process of recovering and releasing the stent using a particle-loaded stent delivery system of the present application is as follows:
步骤一、如图7所示,将支架回收管108安装于外管102的远端,并使所述外管102的远端端部位于所述内管101的远端端部的近端以使所述支架容纳腔106呈开放状态。Step 1, as shown in FIG. 7 , the stent recovery tube 108 is installed on the distal end of the outer tube 102, and the distal end of the outer tube 102 is positioned at the proximal end of the distal end of the inner tube 101 so that Make the stent accommodating chamber 106 in an open state.
步骤二、锚定支架:如图6所示,将处于膨胀状态的空载的可载粒子支架200套设于所述支架容纳腔106的外侧,并使可载粒子支架200的近端编织丝挂设在锚定件107上。此时,可载粒子支架200的近端段呈喇叭形网状结构,而可载粒子支架200的其他部分呈膨胀状态。Step 2, anchoring the stent: as shown in FIG. 6 , the unloaded particle-loaded stent 200 in the expanded state is sleeved on the outside of the stent-accommodating cavity 106, and the proximal end of the particle-loaded stent 200 is braided with wire Hang on the anchor 107. At this time, the proximal section of the particle-loaded stent 200 is in a trumpet-shaped network structure, while other parts of the particle-loaded stent 200 are in an expanded state.
步骤三、预定位:使所述外管102朝向所述内管101的远端移动至所述可载粒子支架200上的粒子仓位于所述外管102的远端之外,在此过程中,所述支架回收管108朝向所述可载粒子支架200处于膨胀状态的一端移动并使可载粒子支架200中穿过所述支架回收管108的对应部分向内收拢后进入所述外管102的第一内腔105内。Step 3, pre-positioning: make the outer tube 102 move toward the distal end of the inner tube 101 until the particle compartment on the loadable particle rack 200 is located outside the distal end of the outer tube 102, during this process , the stent recovery tube 108 moves toward one end of the particle-loaded stent 200 in an expanded state, and the corresponding part of the particle-loaded stent 200 passing through the stent recovery tube 108 is folded inward and enters the outer tube 102 Inside the first lumen 105 of the
步骤四、装填支架:如图14所示,采用粒子植入器300将放射性粒子装载入所述可载粒子支架200上的粒子仓。Step 4. Loading the rack: as shown in FIG. 14 , the radioactive particles are loaded into the particle compartment on the particle-loadable rack 200 by using the particle implanter 300 .
步骤五、回收支架:使所述外管102朝向所述内管101的远端移动至所述可载粒子支架200处于完全收拢状态并容纳于所述支架容纳腔106内,如图10所示。回收支架后、向体内植入支架前将支架回收管108从该输送系统100上拆除。Step 5, recovering the stent: moving the outer tube 102 toward the distal end of the inner tube 101 until the particle-loaded stent 200 is in a fully collapsed state and accommodated in the stent accommodating cavity 106, as shown in FIG. 10 . After recovering the stent and before implanting the stent into the body, the stent recovery tube 108 is removed from the delivery system 100 .
步骤六、释放支架:使所述外管102朝向所述内管101的近端移动至所述支架容纳腔106的周向完全敞开,在此过程中,所述可载粒子支架200从远端及近端逐步自然释放,最终所述可载粒子支架200的近端与所述锚定件107相脱离,从而实现将可载粒子支架200释放至植入区域。Step 6. Release the stent: move the outer tube 102 toward the proximal end of the inner tube 101 until the circumferential direction of the stent accommodating cavity 106 is completely open. During this process, the particle-loaded stent 200 is and the proximal end gradually and naturally release, and finally the proximal end of the particle-loaded stent 200 is detached from the anchor 107, thereby realizing the release of the particle-loaded stent 200 to the implantation area.
相比于现有技术中的先对释放状态下的可载粒子支架上装填粒子、再以手动挤压的方式使装填后的可载粒子支架逐段地收拢后进入外管的内部的回收过程,本申请的回收过程中不存在需要操作者直接接触装载有放射粒子的支架的环节,因此本申请有助于降低放射性粒子对操作者的辐射风险。同时,在本申请中,由于设置支架回收管,可载粒子支架中穿过支架回收管的对应段在支架回收管引导下向内连续地、平滑的收拢,该回收可载粒子支架的过程相比于现有技术逐段手工挤压的过程更便捷快速,能够提高手术的效率和安全性,节约手术时间。Compared with the recovery process in the prior art that firstly loads particles on the loadable particle holder in the released state, and then manually squeezes the loaded particle holder into the interior of the outer tube after being folded up section by section In the recovery process of the present application, there is no link that requires the operator to directly contact the bracket loaded with radioactive particles, so the present application helps to reduce the radiation risk of radioactive particles to the operator. At the same time, in this application, due to the setting of the support recovery tube, the corresponding section of the loadable particle support that passes through the support recovery tube is continuously and smoothly folded inward under the guidance of the support recovery tube, and the process of recovering the loadable particle support is similar. Compared with the process of manual extrusion segment by segment in the prior art, it is more convenient and faster, can improve the efficiency and safety of the operation, and save the operation time.
相比于现有技术中将装填有放射性粒子的支架通过手工挤压的方式装入植入器,本申请提供的一种可载粒子支架输送系统,更便于回收与释放支架,并降低了操作者受辐射的风险。Compared with the prior art where the stent loaded with radioactive particles is manually squeezed into the implanter, the particle-loaded stent delivery system provided by the present application is more convenient for recovering and releasing the stent, and reduces the operating time. risk of exposure to radiation.
本发明提供了一种可载粒子支架输送系统的思路及方法,具体实现该技术方案的方法和途径很多,以上所述仅是本发明的优选实施方式,应当指出,对于本技术领域的普通技术人员来说,在不脱离本发明原理的前提下,还可以做出若干改进和润饰,这些改进和润饰也应视为本发明的保护范围。本实施例中未明确的各组成部分均可用现有技术加以实现。The present invention provides an idea and method of a particle-carrying stent delivery system. There are many methods and approaches to realize this technical solution. The above description is only a preferred embodiment of the present invention. As far as people are concerned, some improvements and modifications can be made without departing from the principle of the present invention, and these improvements and modifications should also be regarded as the protection scope of the present invention. All components that are not specified in this embodiment can be realized by existing technologies.
Claims (10)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310593892.XA CN116549873A (en) | 2023-05-24 | 2023-05-24 | A carrier delivery system for loadable particles |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310593892.XA CN116549873A (en) | 2023-05-24 | 2023-05-24 | A carrier delivery system for loadable particles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116549873A true CN116549873A (en) | 2023-08-08 |
Family
ID=87503367
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202310593892.XA Pending CN116549873A (en) | 2023-05-24 | 2023-05-24 | A carrier delivery system for loadable particles |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN116549873A (en) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH707319A1 (en) * | 2012-12-11 | 2014-06-13 | Carag Ag | Stent applicator. |
| WO2015055070A1 (en) * | 2013-10-14 | 2015-04-23 | 黄景陶 | Placement device capable of accurately positioning human body endoluminal stent |
| WO2019011274A1 (en) * | 2017-07-14 | 2019-01-17 | 先健科技(深圳)有限公司 | Implant delivery system |
| CN212816660U (en) * | 2020-05-15 | 2021-03-30 | 常州贺利氏微创医疗器械有限公司 | Auxiliary placing device for support |
| CN114081696A (en) * | 2021-12-27 | 2022-02-25 | 赛诺神畅医疗科技有限公司 | Vascular stent releasing device |
| CN220070513U (en) * | 2023-05-24 | 2023-11-24 | 苏州融晟医疗科技有限公司 | Particle-carrying support conveying system |
-
2023
- 2023-05-24 CN CN202310593892.XA patent/CN116549873A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH707319A1 (en) * | 2012-12-11 | 2014-06-13 | Carag Ag | Stent applicator. |
| WO2015055070A1 (en) * | 2013-10-14 | 2015-04-23 | 黄景陶 | Placement device capable of accurately positioning human body endoluminal stent |
| WO2019011274A1 (en) * | 2017-07-14 | 2019-01-17 | 先健科技(深圳)有限公司 | Implant delivery system |
| CN212816660U (en) * | 2020-05-15 | 2021-03-30 | 常州贺利氏微创医疗器械有限公司 | Auxiliary placing device for support |
| CN114081696A (en) * | 2021-12-27 | 2022-02-25 | 赛诺神畅医疗科技有限公司 | Vascular stent releasing device |
| CN220070513U (en) * | 2023-05-24 | 2023-11-24 | 苏州融晟医疗科技有限公司 | Particle-carrying support conveying system |
Non-Patent Citations (1)
| Title |
|---|
| 李红昕, 邹承伟, 郭兰敏, 訾捷, 王正军: "覆膜支架治疗胸降主动脉夹层", 山东医药, no. 33, 28 September 2006 (2006-09-28) * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105078615B (en) | Interior tube assembly for implant delivery system | |
| EP2491894B1 (en) | Stent delivery device with rolling stent retaining sheath | |
| US6090035A (en) | Stent loading assembly for a self-expanding stent | |
| RU2737289C2 (en) | Catheter system for use in delivery and deployment of intravascular device | |
| JP2908982B2 (en) | Device for releasing a self-expanding endoprosthesis | |
| CN105105870B (en) | Heart valve conveying device | |
| JP2011522591A (en) | Introducer | |
| CN115023200A (en) | Methods and assemblies for securing an implantable medical device to a delivery system | |
| CN104983485B (en) | Valve connecting mechanism of heart valve conveying device | |
| CN1901851A (en) | Vascular Implants | |
| CN103179919A (en) | Devices and methods for loading a prosthesis onto a delivery system | |
| US20090171434A1 (en) | Prosthesis loading delivery and deployment apparatus | |
| CN107374792A (en) | A kind of integral type layered-scaffold implanting device | |
| CN204814284U (en) | Artificial heart valve conveyor | |
| CN106333774A (en) | Lumen stent conveying system | |
| US20050222664A1 (en) | Prosthesis deployment system | |
| CN220070513U (en) | Particle-carrying support conveying system | |
| JPH1076015A (en) | Device for taking out implanted inner artificial organ | |
| CN116549873A (en) | A carrier delivery system for loadable particles | |
| US12336923B2 (en) | Scaffold loading and delivery systems | |
| US20120065644A1 (en) | Stent deployment system with retractable shealth | |
| US11399844B2 (en) | Medical device holding and delivery assembly and kit therefor | |
| CN115568918A (en) | Positioning puncture device | |
| CN109498206B (en) | Implant retrieval apparatus and use and packaging thereof | |
| CN210095994U (en) | Sheath tube for implant recovery, implant catcher and package thereof, and implant recovery device and package thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |