CN116407395A - Oviduct embolism instrument and oviduct embolism system - Google Patents

Abstract

In the oviduct embolism apparatus and the oviduct embolism system of the invention, the apparatus comprises: the plug body is provided with a first-level morphology and a second-level morphology, and the outer side of the plug body is used for being abutted against the inner side of the oviduct; the first-order morphology comprises a columnar morphology; the second-level form is formed by changing the extending direction of the first-level form; the plug body can be stretched from the secondary form to the primary form under the action of external force, and after the external force is removed, the plug body can be restored from the primary form to the secondary form. The plug body is implanted into the oviduct from the primary form under the action of external force, and is restored to the secondary form in the oviduct after the external force is removed, the plug body in the secondary form can play a good role in anchoring and supporting the oviduct after being attached to the inner side of the oviduct, the volume of a part of the plug body actually used for plugging can be correspondingly increased, and the filling compactness of the plug body and the oviduct is improved, so that the plug effect of the oviduct plug instrument is improved.

Description

Fallopian tube embolization device and fallopian tube embolization system

technical field

The invention relates to the technical field of medical devices, in particular to a fallopian tube embolization device and a fallopian tube embolization system.

Background technique

In the existing tubal embolization operation, an embolization device is usually used to mechanically embolize the fallopian tube in a physical way. During the operation, the embolization device is transported to the interstitium and isthmus of the fallopian tube to complete embolization. Or permanent means of contraception, and in other scenarios it is also used as hydrosalpinx embolization treatment for patients with hydrosalpinx before IVF.

However, the state of the existing embolization device before and after implantation into the fallopian tube is basically the same, which usually results in a smaller volume of the part where the embolization device is actually used for embolization, and the embolization device is not compatible with the anchor of the fallopian tube. The setting effect is also relatively poor, and it is easy to move in the fallopian tubes. All of the above will cause the embolization device to have a less than ideal embolization effect on the fallopian tubes. In addition, the existing embolization devices are mostly used for contraception in healthy women. At present, there is no ideal tubal embolization method to help patients who are preparing for IVF but have hydrosalpinx.

Contents of the invention

The purpose of the present invention is to provide a fallopian tube embolization device and a fallopian tube embolization system, so as to solve the problem that the existing embolization device has an unsatisfactory embolization effect on the fallopian tube.

In order to solve the above-mentioned technical problems, based on one aspect of the present invention, the present invention provides a fallopian tube embolization device, which includes: a plug body with a primary shape and a secondary shape, and the outside of the plug body is used to stick to the inside of the fallopian tube. rely on; the primary form includes a columnar form; the secondary form is formed by changing the extension direction of the primary form; the plug body can be stretched from the secondary form to the The first-order form, and after the external force is removed, the plug body can recover from the first-order form to the second-order form.

Optionally, the secondary shape includes one or a combination of at least two of wave shape, spiral shape and polyhedron shape.

Optionally, the plug body includes at least one anchor segment and at least one plug segment, and the anchor segment is connected to the plug segment.

Optionally, the plug body includes one anchor segment and two plug segments, and the anchor segment is located between the two plug segments.

Optionally, when the plug body includes at least two anchor segments and at least two plug segments, one anchor segment is arranged between two adjacent plug segments, and A section of the embolization section is arranged between two adjacent sections of the anchor section.

Optionally, when the plug body includes at least two plug segments, at least some of the plug segments have different radial dimensions; and/or,

When the plug body includes at least two anchor segments, at least a part of the anchor segments have different radial dimensions.

Optionally, the fallopian tube embolization device includes an anti-unwinding wire, the shape of the anti-unwinding wire is adapted to the secondary shape of the embolization body, and the two ends of the anti-unwinding wire are respectively connected to the embolization body both ends.

Optionally, the plug body in the primary form has an inner cavity penetrating along its axial direction.

Optionally, the first-order shape of the plug body is formed according to a thread helically coiled.

Optionally, the primary form of the plug body includes a network structure with multiple grids formed by crossing strands of wires.

Optionally, the wire diameter of a single strand of the wire is greater than or equal to 0.0001 inch and less than or equal to 0.0070 inch.

Optionally, the primary shape of the plug body is formed according to the axial extension of the balloon itself.

Optionally, the radial dimension of the plug body in the primary form is greater than or equal to 0.01 mm and less than or equal to 2 mm.

Optionally, the axial dimension of the plug body in the primary form is greater than or equal to 0.1 cm and less than or equal to 30 cm.

Optionally, the fallopian tube embolization device includes a first coating, the first coating is coated on the outer surface of the embolization body, and the first coating has a water-swellable property.

Optionally, the fallopian tube embolization device includes a mandrel, the mandrel is arranged inside the embolization body, and the mandrel extends along the axial direction of the embolization body, and the mandrel has a water-swellable Attributes.

Optionally, the fallopian tube embolization device includes a second coating, the second coating covers the outer surface of the embolization body, and the second coating includes a drug coating.

Optionally, the outer surface of the plug body is provided with a fiber structure.

Optionally, the material of the plug body includes degradable materials.

Based on another aspect of the present invention, the present invention also provides a fallopian tube embolization system, which includes:

a tubal embolization device as described above; and

A delivery instrument, which is detachably connected to the fallopian tube embolization instrument and used to drive the fallopian tube embolization instrument to be implanted into the fallopian tube.

In summary, in the fallopian tube embolization device and fallopian tube embolization system provided by the present invention, the fallopian tube embolization device includes: an embolization body with a primary form and a secondary form, and the outside of the embolization body is used to abut against the inner side of the fallopian tube; The secondary form includes columnar form; the secondary form is formed by changing the extension direction of the primary form; the plug body can be stretched from the secondary form to the primary form under the action of external force, and after the external force is removed, the plug body can be stretched from the primary form Form reverts to secondary form. As configured above, the primary shape of the plug body includes a columnar shape, that is, the extension direction of the primary shape is a linear direction, and the secondary shape of the plug body is formed by changing the extension direction of the primary shape, that is, the extension direction of the secondary shape is nonlinear Direction, with more degrees of freedom in space, the embolism body is implanted in the fallopian tube from the primary form under the action of external force, and returns to the secondary form in the fallopian tube after the external force is removed, the embolism body in the secondary form and the fallopian tube After the inner side of the embolism is attached, the plug body can play a good role in anchoring and supporting the fallopian tubes, and the volume of the part where the plug body in the secondary form is actually used for embolization can also be correspondingly increased, improving the relationship between the plug body and the fallopian tube. The filling compactness of the fallopian tubes can improve the embolization effect of the fallopian tube embolization device, which can help healthy women to prevent pregnancy normally and help patients who are preparing for IVF surgery but have hydrosalpinx to reduce the leakage rate.

Description of drawings

Those skilled in the art should understand that the accompanying drawings are provided for better understanding of the present invention, and do not constitute any limitation to the scope of the present invention. in:

FIG. 1 is a schematic diagram of the secondary form of the plug body of Embodiment 1 of the present invention;

Fig. 2 is another schematic diagram of the secondary form of the plug body of the first embodiment of the present invention;

Fig. 3 is another schematic diagram of the secondary form of the plug body in Embodiment 1 of the present invention;

Fig. 4 is a schematic diagram of the primary form of the plug body of the second embodiment of the present invention;

Fig. 5 is a schematic diagram of the secondary form of the plug body of the second embodiment of the present invention;

Fig. 6 is another schematic diagram of the secondary form of the plug body of the second embodiment of the present invention;

Fig. 7 is a schematic diagram of the primary form of the plug body of the third embodiment of the present invention;

Fig. 8 is another schematic diagram of the primary form of the plug body of the third embodiment of the present invention;

Fig. 9 is a schematic diagram of the secondary form of the plug body of the third embodiment of the present invention;

Fig. 10 is a schematic diagram of a plug body according to Embodiment 4 of the present invention.

In the attached picture:

10-embolization body; 11-anchor segment; 12-embolization segment; balloon 100.

Detailed ways

In order to make the purpose, advantages and features of the present invention clearer, the present invention will be further described in detail below in conjunction with the accompanying drawings and specific embodiments. It should be noted that the drawings are all in very simplified form and not drawn to scale, and are only used to facilitate and clearly assist the purpose of illustrating the embodiments of the present invention. In addition, the structures shown in the drawings are often a part of the actual structures. In particular, each drawing needs to display different emphases, and sometimes uses different scales.

As used in the present invention, the singular forms "a", "an" and "the" include plural objects, the term "or" is usually used in the sense of including "and/or", and the term "several" Usually, the term "at least one" is used in the meaning of "at least one", and the term "at least two" is usually used in the meaning of "two or more". In addition, the terms "first", "second "Two" and "third" are used for descriptive purposes only, and should not be understood as indicating or implying relative importance or implicitly indicating the quantity of the indicated technical features. Thus, the features defined as "first", "second", and "third" may expressly or implicitly include one or at least two of these features, "one end" and "another end" and "near end" and "near end" "Remote" usually refers to the corresponding two parts, which not only includes the terminal, the terms "installation", "connection", and "connection" should be understood in a broad sense, for example, it can be a fixed connection or a detachable connection, or Integrate; can be mechanical connection, can also be electrical connection; can be directly connected, can also be indirectly connected through an intermediary, can be the internal communication of two components or the interaction relationship between two components. In addition, as used in the present invention, an element is arranged on another element, usually only means that there is a connection, coupling, cooperation or transmission relationship between the two elements, and the relationship between the two elements can be direct or indirect through an intermediate element. connection, coupling, fit or transmission, but cannot be understood as indicating or implying the spatial positional relationship between two elements, that is, one element can be in any orientation such as inside, outside, above, below or on one side of another element, unless the content Also clearly point out. Those of ordinary skill in the art can understand the specific meanings of the above terms in the present invention according to specific situations.

The invention provides a fallopian tube embolization device and a fallopian tube embolization system to solve the problem that the existing embolization device has an unsatisfactory embolization effect on the fallopian tube.

The fallopian tube embolization device of this embodiment includes an embolization body 10 having a primary form and a secondary form. The extending direction of the form is a linear direction; the secondary form is formed by changing the extending direction of the primary form, which can be understood as the extending direction of the secondary form is a non-linear direction, such as an arc direction, etc., so, The plug body 10 in the secondary form can have greater freedom in space; the plug body 10 can be stretched from the secondary form to the primary form under the action of an external force, and after the external force is removed, The plug body 10 is revertible from the primary configuration to the secondary configuration. The plug body 10 is implanted into the fallopian tube from the primary form under the action of external force, and recovers to the secondary shape in the fallopian tube after the external force is removed. It has a good anchoring and supporting effect on the fallopian tubes, and the volume of the part where the secondary form of the embolism body 10 is actually used for embolization can also be increased accordingly, improving the filling compactness of the embolism body 10 and the fallopian tubes, thereby Improving the embolization effect of the fallopian tube embolization device can help healthy women to prevent pregnancy normally and help patients who are preparing for IVF but have hydrosalpinx to reduce the leakage rate.

In this embodiment, the secondary shape includes one or a combination of at least two of wave shape, spiral shape and polyhedron shape, which can improve the matching effect between the plug body 10 and the fallopian tube. The polyhedral form can be, for example, a spherical form, a hexahedral form, or other three-dimensional forms. The secondary form can increase the dense embolization rate (dense embolization density) of the fallopian tube and enhance the embolization effect. Understandably, the dense embolization rate refers to the cross-sectional effective area of the plug body 10 and the cross-sectional area of the fallopian tube at the corresponding part. Preferably, the secondary shape is preferably a polyhedron shape, which can further increase the density of dense plugs. Further, taking the spiral shape of the secondary form as an example, the plug body 10 first takes a spiral shape outside the body of the patient. For example, the plug body 10 can first form a secondary shape through a heat setting process, and then stretch it into a columnar shape under the action of an external force. shape, and then implanted into the fallopian tube of the patient under the action of the delivery instrument, and finally withdraw the delivery instrument, and the plug body 10 recovers from the columnar form to the spiral form in the fallopian tube.

The embolization body of the fallopian tube embolization device of the present invention will be described in detail below with reference to the accompanying drawings and specific embodiments.

[Example 1]

Please refer to Figures 1 to 3 for this embodiment, wherein Figure 1 is a schematic diagram of the secondary form of the plug body in Embodiment 1 of the present invention; Figure 2 is another schematic diagram of the secondary form of the plug body in Embodiment 1 of the present invention , FIG. 3 is another schematic diagram of the secondary form of the plug body of Embodiment 1 of the present invention.

Specifically, the plug body 10 of the primary form has a lumen (not shown) penetrating in its axial direction, that is, the plug body 10 is roughly tubular. It can be understood that the cross-section of the lumen in this embodiment The shape is not particularly limited, and may be circular, square or irregular planar shape. Preferably, the cross-sectional shape of the lumen is the same as the contour shape of the plug body 10 , for example, both are circular.

Further, the primary shape of the plug body 10 is formed according to a thread helically coiled. In this way, the primary form of the plug body 10 is roughly in the shape of a spring or bellows (hypotube), and the secondary form can be a wave form (shown in FIG. 1 ) or a helical form (shown in FIG. 2 ) with the spring shape as a single body. shown), polyhedral shape, etc. Of course, the secondary form of the embolism body 10 can also be a combination of the above-mentioned forms. For example, the secondary form in Figure 3 is a combination of a spring shape and a polyhedral form, that is, the left side is a spiral form, and the right side is a spiral form. Polyhedral shape, the helical shape plays an anchoring role, and the polyhedral shape is more conducive to dense packing after the instrument is delivered to the target site or under the further extrusion of the operator using an external instrument (such as a guide wire), and because the polyhedral shape has no helical The hollow structure of the shape makes the packing effect better. The general choice of polymorphic combination is to take into account both anchoring and dense packing. Furthermore, the wire diameter of a single strand of the wire is greater than or equal to 0.0001 inch and less than or equal to 0.0070 inch, where the wire diameter of the wire can be understood as the thickness of the wire. The material of the wire is, for example, a shape memory alloy.

[Example 2]

Please refer to Fig. 4 to Fig. 6 for this embodiment, wherein Fig. 4 is a schematic diagram of the primary form of the plug body according to Embodiment 2 of the present invention; Fig. 5 is a schematic diagram of the secondary form of the plug body according to Embodiment 2 of the present invention; Fig. 6 It is another schematic diagram of the secondary form of the plug body of the second embodiment of the present invention.

Specifically, the plug body 10 of the primary form has a lumen (not shown) penetrating in its axial direction, that is, the plug body 10 is roughly tubular. It can be understood that the cross-section of the lumen in this embodiment The shape is not particularly limited, and may be circular, square or irregular planar shape. Preferably, the cross-sectional shape of the lumen is the same as the contour shape of the plug body 10 , for example, both are circular.

Further, the first-order form of the plug body 10 includes a network structure with multiple grids formed by crossing strands of wires. The network structure can be one or more layers. The mesh structure of the pipe wall. Furthermore, the wire diameter of a single strand of the wire is greater than or equal to 0.0001 inch and less than or equal to 0.0070 inch, and the material of the wire is, for example, a shape memory alloy, such as nickel-titanium wire. The secondary form of the embolism body 10 forms a wavy form, a spiral form, a polyhedral form, etc. with a tubular network structure, and can also be a combination of at least two of the secondary forms. For example, Figure 6 demonstrates that a tubular network structure forms a wave form and A combination of polyhedral shapes formed.

[Embodiment 3]

Please refer to Figure 7 to Figure 9 for this embodiment, Figure 7 is a schematic diagram of the primary form of the plug body in Embodiment 3 of the present invention, and Figure 8 is another schematic diagram of the primary form of the plug body in Embodiment 3 of the present invention, Fig. 9 is a schematic diagram of the secondary form of the plug body of the third embodiment of the present invention.

The primary form of the plug body 10 is formed according to the extension of the balloon 100 along its own axial direction. Further, the primary form of the plug body 10 can be based on one (shown in FIG. 7 ) or multiple balloons 100 (shown in FIG. 9 ). (shown) is formed, and when there are multiple balloons, the multiple balloons 100 are sequentially connected along the axial direction. In this way, the primary form of the plug body 10 is approximately ellipsoidal, and the secondary form can be ellipsoidal to form waves, spirals (as shown in FIG. 9 ), polyhedrons, etc. The balloon 100 is delivered into the fallopian tube in a contracted state, and then a filling medium can be added into the balloon 100 to restore the balloon 100 to an expanded state, so that the embolism body 10 returns to the primary form, or directly returns to the secondary form. Of course, in this embodiment, filling medium can also be added to the inside of the balloon 100 outside the patient's body to restore the balloon 100 to the expanded state, so that the embolism body 10 can be directly restored to a secondary state, and then stretched by an external force to make the two The secondary form is restored to the primary form, and then the plug body 10 is implanted into the fallopian tube, and after the external force is removed, the plug body 10 formed by the balloon 100 returns to the secondary form again. The filling medium is, for example, contrast medium or saline. The balloon 100 may be a compliant balloon 100 or a semi-compliant balloon 100 .

It should be noted that the descriptions of the first, second and third embodiments above about the primary and secondary forms of the embolism body can be used for reference. Corresponding description sections for other examples.

[Example 4]

Please refer to FIG. 10 for this embodiment. FIG. 10 is a schematic diagram of a plug body according to Embodiment 4 of the present invention.

It should be noted that the specific formation structure of the plug body 10 in the fourth embodiment and the shape of the anchoring section 11 and the shape of the plugging section 12 can refer to the description of the first embodiment, the second embodiment or the third embodiment, and will not be repeated here. Repeat instructions.

In this embodiment, the plug body 10 includes at least one anchor segment 11 and at least one plug segment 12 , and the anchor segment 11 is connected to the plug segment 12 . Specifically, after the embolism body 10 is implanted into the fallopian tube, the anchoring section 11 is mainly anchored and fitted to the thinner part of the fallopian tube to fix the embolism body 10, and the embolism section 12 is located in the thicker part of the fallopian tube to play an embolizing role. , this setting can better fit the fallopian tube, improve the embolization effect, and reduce the foreign body sensation of the patient. Therefore, after the plug body 10 is implanted into the fallopian tube, due to the limitation of the fallopian tube and the positional arrangement of the anchor segment 11 and the plug segment 12 of the plug body, the radial dimension of the anchor segment 11 is usually smaller than the radial size of the plug segment 12, It can be understood that the radial dimension here refers to the largest dimension along the radial direction, and if the cross section of the plug body 10 is circular, it refers to the diameter. It should be noted that, before the plug body 10 is implanted into the fallopian tube, that is, the plug body 10 is not restricted by the fallopian tube and is in a natural state, the radial size of the anchoring segment 11 and the radial size of the plug segment 12 are not limited. , the two can be equal or unequal, and the radial dimension of the anchoring segment 11 can also be greater than the radial dimension of the embolic segment 12 .

It should be noted that this embodiment does not limit the shape of the anchoring section 11 and the embolization section 12, for example, both of them present the embolization body 10 in the primary form, or the embolization body 10 in the second form, Or one of them presents the plug body 10 of the primary form, and the other presents the plug body 10 of the secondary form. For example, the anchoring segment 11 is in a columnar shape, and the plugging segment 12 is in a spiral shape; the anchoring segment 11 is in a wave shape, and the plugging segment 11 is in a spherical shape; the anchoring segment 11 is in a spiral shape, and the plugging segment 12 is in a hexahedral shape; Personnel can be combined arbitrarily, and will not be listed one by one here.

Further, the plug body 10 includes one anchor segment 11 and two plug segments 12 , and the anchor segment 11 is located between the two plug segments 12 . The fallopian tube includes the ampulla, isthmus and interstitium that are connected in sequence, and the radial dimensions of the ampulla and the interstitium are larger than the radial dimension of the isthmus. By setting one anchor segment 11 and two embolization segments 12. The anchoring section 11 can be anchored in the isthmus to play the role of anchoring and fixing. The two embolization sections 12 are respectively located in the ampulla and the interstitial part to play the role of fallopian tube embolization. In this way, the matching effect between the plug body 10 and the fallopian tube can be improved, the foreign body sensation of the patient can be further reduced, and the plug body 10 can be prevented from moving to the uterus or to the ovary when the patient is at rest or in motion.

Preferably, when the plug body 10 includes at least two anchor segments 11 and at least two plug segments 12, one anchor segment 11 is arranged between two adjacent segments of the plug segments 12, and adjacent A section of the embolic section 12 is arranged between the two sections of the anchoring section 11 . With this arrangement, on the one hand, the anchoring segments 11 can be evenly arranged, and the embolization segments 12 can be _evenly arranged; =p _plug 1*p _plug 2*...*p _{plug n} , wherein P _{plug n} represents the leakage rate of the nth plug segment. That is, when each embolism segment leaks, the overall failure will occur. For patients with hydrosalpinx, the leakage rate of the fallopian tubes can be further reduced.

It should be understood that, when the plug body 10 includes at least two plug segments 12 , at least a part of the plug segments 12 may have different radial dimensions. Similarly, when the plug body 10 includes at least two anchoring segments 11 , at least a part of the anchoring segments 11 may have different radial dimensions.

[Embodiment 5]

It should be noted that, as a preferred embodiment for describing the fallopian tube embolization device, the fifth embodiment focuses on explaining the preferred scheme of the fallopian tube embolization device on the basis of the embolization body. For the description of the structure of the embolization body, refer to the above-mentioned embodiment 1 and embodiment 2. The description of Embodiment 3 and Embodiment 4 will not be repeated here.

In this embodiment, the radial dimension of the plug body 10 in the primary form is greater than or equal to 0.01 mm and less than or equal to 2 mm; the axial dimension (length) of the plug body 10 in the primary form is greater than or equal to 0.1cm, and less than or equal to 30cm. In actual scenarios, the operator can configure the embolization body 10 with appropriate radial and axial dimensions according to the condition of the patient's fallopian tubes, so as to fit the patient's fallopian tubes to the greatest extent and avoid the embolization body 10 from being implanted as much as possible. After arriving at the patient's fallopian tube, the patient feels a foreign body sensation. In addition, choose an embolism body 10 with an appropriate axial size to avoid the short size that cannot be effectively embolized, and avoid the possibility of falling into the ampulla of the fallopian tube or even the ovary if the size is too long.

Preferably, the fallopian tube embolization device includes an anti-untwisting wire, the shape of the anti-untwisting wire is adapted to the secondary shape of the embolization body 10, and the two ends of the anti-untwisting wire are respectively connected to the embolization body 10 ends. The setting of the anti-untwisting wire can limit the extensibility (axial extension) of the embolism body 10, and prevent the secondary form of the embolism body 10 from being released due to external pressure after it is implanted into the fallopian tube. For example, when the plug body 10 is helically wound to form a spring shape, the anti-untwisting wire can prevent the spring-shaped plug body 10 from being elongated and untwisted. The anti-untwisting thread can be, for example, an elastic polymer material or a surgical suture.

Preferably, the fallopian tube embolization device includes a first coating, the first coating is coated on the outer surface of the embolization body 10, and the first coating has a water-swellable property. After the embolism body 10 is implanted into the fallopian tube, the first coating can swell with water to fill the gap between the embolism body 10 and the inner side of the fallopian tube and improve the filling compactness. The first coating can be, for example, a gel coat.

Preferably, the fallopian tube embolization device includes a mandrel, the mandrel is arranged inside the embolization body 10, and the mandrel extends along the axial direction of the embolization body 10, and the mandrel has a water-swellable properties. After the plug body 10 is implanted into the fallopian tube, the mandrel swells with water, thereby driving the plug body 10 to expand outward, so that the outside of the plug body 10 fits closely with the inside of the fallopian tube, improving the filling compactness.

Optionally, the fallopian tube embolization device of this embodiment can also be used in combination with gel. After the fallopian tube embolization device is implanted into the fallopian tube, an appropriate amount of gel can be injected from the fallopian tube orifice to achieve a complete occlusion effect.

Optionally, the fallopian tube embolization device includes a second coating, the second coating is coated on the outer surface of the embolization body 10, and the second coating includes a drug coating. The drug coating can improve the biocompatibility of the fallopian tube embolization device, inhibit the endothelial cell proliferation and inflammation of the fallopian tube. For healthy women, the drug coating can be coated with a slow-release spermicidal drug, which is used for the contraceptive needs of healthy women.

Preferably, the outer surface of the plug body 10 is provided with fiber structures, such as fiber fluff. The outer surface of the embolization body 10 is provided with fiber villi, which can increase the compatibility with the inner wall of the fallopian tube. After a period of time after the operation, aseptic inflammation will occur around the embolization body 10, thereby further strengthening the embolization effect with the fallopian tube.

Preferably, the material of the plug body 10 includes degradable materials, specifically biodegradable materials, such as polylactic acid, polyhydroxy acid and polypeptide, polyglycolic acid [poly (glycolic acid), PGA], polycaprolactone (polycaprolactam, PCL), polyether, polycarbonate, etc. The plug body 10 made of degradable material can be dissolved in the human body after a period of use and can be absorbed by the human body, avoiding injury and discomfort to the patient during the process of removing the plug body 10 from the fallopian tube.

Based on the above-mentioned fallopian tube embolization device, the present invention also provides a fallopian tube embolization system, which includes the above-mentioned fallopian tube embolization device and a delivery device, the delivery device is detachably connected with the fallopian tube embolization device, and is used to drive the A tubal embolization device is inserted into the fallopian tubes. This embodiment does not limit the specific structure of the delivery device, and those skilled in the art can make preferred configurations according to the prior art. For example, the delivery device and the fallopian tube embolization device are connected by a release structure, and the release structure can be a mechanical release structure, a hydrolysis release structure or an electrolysis release structure, so as to ensure that the fallopian tube embolization device of the present invention has an ideal implantation effect in the fallopian tube, it can be It is convenient to separate the delivery device and the fallopian tube embolization device from each other. In addition, when the implantation effect of the fallopian tube embolization device in the fallopian tube is poor, the delivery device can also temporarily recover the fallopian tube embolization device into the inner sheath, and then re-implant and release it.

In summary, in the fallopian tube embolization device and the fallopian tube embolization system provided by the present invention, the fallopian tube embolization device includes: an embolization body 10 with a primary form and a secondary form, and the outside of the embolization body 10 is used to abut against the inner side of the fallopian tube The primary form includes a columnar form; the secondary form is formed by changing the extension direction of the primary form; the plug body 10 can be stretched from the secondary form to the primary form under the action of external force, and after the external force is removed, the plug body 10 10 can be restored from the primary form to the secondary form. As configured above, the primary form of the plug body 10 includes a columnar form, that is, the extension direction of the primary form is a linear direction, and the secondary form of the plug body 10 is formed by changing the extension direction of the primary form, that is, the extension direction of the secondary form is The non-linear direction has more degrees of freedom in space. The embolism body 10 is implanted in the fallopian tube from the primary form under the action of external force, and returns to the secondary form in the fallopian tube after the external force is removed. The embolism in the secondary form After the body 10 abuts against the inner side of the fallopian tube, the plug body 10 can play a good role in anchoring and supporting the fallopian tube, and the volume of the part where the plug body 10 in the secondary form is actually used for embolization can also be increased correspondingly. Large, improve the filling compactness of the embolization body 10 and the fallopian tube, thereby improving the embolization effect of the fallopian tube embolization device, which can help healthy women to prevent pregnancy normally and help patients who are preparing for IVF but have hydrosalpinx to reduce the leakage rate.

The above description is only a description of the preferred embodiments of the present invention, and does not limit the scope of the present invention. Any changes and modifications made by those of ordinary skill in the field of the present invention based on the above disclosures belong to the protection scope of the technical solution of the present invention.

Claims (20)

1. A fallopian tube embolization device, characterized in that it comprises: a plug body with a primary form and a secondary form, the outside of the plug body is used to abut against the inner side of the fallopian tube; the primary form includes a columnar form; The secondary form is formed by changing the extension direction of the primary form; the plug body can be stretched from the secondary form to the primary form under the action of external force, and after the external force is removed, the The plug body is revertible from the primary configuration to the secondary configuration. 2 . The fallopian tube embolization device according to claim 1 , wherein the secondary shape includes one or a combination of at least two of wave shape, spiral shape and polyhedron shape. 3 . 3. The fallopian tube embolization device according to claim 1, wherein the embolization body comprises at least one anchoring section and at least one embolization section, and the anchoring section is connected to the embolization section. 4. The fallopian tube embolization device according to claim 3, wherein the embolization body comprises a section of the anchoring section and two sections of the embolization section, and the anchoring section is located between the two sections of the embolization section between. 5. The fallopian tube embolization device according to claim 3, characterized in that, when the embolization body includes at least two anchoring segments and at least two embolization segments, one of the two adjacent embolization segments A section of the anchoring section is arranged between two adjacent sections of the anchoring section, and a section of the embolism section is arranged between two adjacent sections of the anchoring section. 6. The fallopian tube embolization device according to claim 3, 4 or 5, wherein when the embolization body includes at least two embolization sections, at least a part of the embolization sections have different radial dimensions; and /or, When the plug body includes at least two anchor segments, at least a part of the anchor segments have different radial dimensions. 7. The fallopian tube embolization device according to claim 1, characterized in that, the fallopian tube embolization device comprises an anti-untwisting wire, the shape of the anti-untwisting wire is adapted to the secondary shape of the embolization body, and the The two ends of the anti-untwisting wire are respectively connected to the two ends of the plug body. 8 . The fallopian tube embolization device according to claim 1 , wherein the embolization body in the primary form has an inner cavity penetrating along its own axial direction. 9 . 9. The fallopian tube embolization device according to claim 8, characterized in that, the first-order shape of the embolization body is formed according to a thread helically coiled. 10. The fallopian tube embolization device according to claim 8, characterized in that, the first-order form of the embolization body comprises a network structure with multiple grids formed by crossing strands of silk. 11. The fallopian tube embolization device according to claim 9 or 10, characterized in that the diameter of a single strand of the silk thread is greater than or equal to 0.0001 inch and less than or equal to 0.0070 inch. 12. The fallopian tube embolization device according to claim 1, characterized in that, the primary shape of the embolization body is formed according to the axial extension of the balloon itself. 13. The fallopian tube embolization device according to claim 1, characterized in that, the radial dimension of the embolization body in the primary form is greater than or equal to 0.01 mm and less than or equal to 2 mm. 14. The fallopian tube embolization device according to claim 1, characterized in that the axial dimension of the embolization body in the primary form is greater than or equal to 0.1 cm and less than or equal to 30 cm. 15. The fallopian tube embolization device according to claim 1, characterized in that, the fallopian tube embolization device comprises a first coating, the first coating is coated on the outer surface of the embolization body, and the first coating Layers have the property of swelling when exposed to water. 16. The fallopian tube embolization device according to claim 1, characterized in that, the fallopian tube embolization device comprises a mandrel, the mandrel is arranged inside the embolization body, and the mandrel is along the Extending axially, the mandrel has the property of swelling with water. 17. The fallopian tube embolization device according to claim 1, characterized in that, the fallopian tube embolization device comprises a second coating, the second coating is coated on the outer surface of the embolization body, and the second coating The layer includes a drug coating. 18. The fallopian tube embolization device according to claim 1, characterized in that, the outer surface of the embolization body is provided with a fiber structure. 19. The fallopian tube embolization device according to claim 1, wherein the material of the embolization body includes degradable materials. 20. A fallopian tube embolization system, comprising: The fallopian tube embolization device according to any one of claims 1-19; and A delivery instrument, which is detachably connected to the fallopian tube embolization instrument and used to drive the fallopian tube embolization instrument to be implanted into the fallopian tube.

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