CN114831697A - Shock wave generating device for molding internal cavity - Google Patents

Abstract

The invention provides a shock wave generating device for shaping a body cavity, which belongs to the field of medical instruments and comprises: the device comprises a carrier, a first inner electrode, a second inner electrode, an insulating protective sleeve and a balloon; the first internal electrode and the second internal electrode are respectively arranged on two opposite sides of the outer surface of the carrier; the first inner electrode and the second inner electrode are connected with an external power supply through leads; the saccule is wrapped on the carrier, a closed space is formed between the saccule and the carrier, liquid is filled in the closed space, and the two inner electrodes are positioned in the closed space; the insulating protective sleeve is sleeved on the carrier and covers the two inner electrodes; the insulating protective sleeve is provided with an opening or a slit to expose two partial inner electrodes, when the shock wave generating device acts on a human blood vessel, under the action of an external power supply, the first inner electrode is conducted with the second inner electrode through liquid, so that shock wave energy is generated in the balloon, calcified tissues at corresponding positions in a broken blood vessel are further broken, and the breaking efficiency of the calcified tissues is improved.

Description

A shock wave generating device for body cavity shaping

technical field

The invention relates to the field of medical instruments, in particular to a shock wave generating device for shaping a cavity in a body.

Background technique

Coronary atherosclerotic heart disease is the stenosis or obstruction of the vascular lumen caused by atherosclerotic lesions in the coronary vessels, resulting in myocardial ischemia, hypoxia or necrosis, also known as coronary heart disease. Drugs, interventions, and surgery are generally available. Among them, interventional therapy has obvious curative effect, less trauma and less pain for patients. The overall efficacy is the same as that of coronary artery bypass grafting, and it is significantly better than simple drug treatment. This technology has been favored by clinicians and patients.

In 1977, Gruentzig successfully performed the world's first balloon angioplasty (ie PTCA surgery) for a patient with proximal anterior descending coronary artery stenosis using a balloon catheter, creating a new era of coronary interventional therapy. In the past ten years, balloon stent technology has developed rapidly, becoming smaller in size and stronger in expansion force. At the same time, certain clinical experience has also been accumulated.

At present, the shockwave company has developed most of the balloon catheters to achieve vascular dilation devices. Its patent application number 201380041656.1 provides a low-profile electrode for angioplasty shockwave catheters, wherein the first inner electrode is in the balloon. The second inner electrode is located at the first side position of the elongated member, the second inner electrode is located at the second side position offset from the first inner electrode in the circumferential direction, the insulating protective sheath is arranged around the first inner electrode and the second inner electrode, and the outer electrode protective sheath When a voltage is applied between the first inner electrode and the second inner electrode arranged around the insulating protective sheath, current flows from the first inner electrode to the outer electrode protective sheath to the second inner electrode in sequence, so that the first shock wave flows from the first inner electrode to the second inner electrode. A side location is initiated and a second shock wave is induced from the second side location. This solution requires an outer electrode protective sleeve, and the direction of the current can only flow from the first inner electrode to the outer electrode protective sleeve and then to the second inner electrode, which makes the shock wave generation process more complicated and affects the fragmentation efficiency of calcified tissue.

Based on the above problems, there is an urgent need for a new device for in vivo cavity shaping to remove the calcified tissue at the intima of the blood vessel and to improve the fragmentation efficiency of the calcified tissue.

SUMMARY OF THE INVENTION

The purpose of the present invention is to provide a shock wave generating device for shaping a cavity in the body, which can effectively break the calcified tissue in the blood vessel and improve the breaking efficiency of the calcified tissue.

For achieving the above object, the present invention provides the following scheme:

A shock wave generating device for shaping a cavity in the body, the shock wave generating device for shaping a cavity in the body comprises: a carrier, a first inner electrode, a second inner electrode, an insulating protective sleeve and a balloon;

The first inner electrode and the second inner electrode are respectively arranged on opposite sides of the outer surface of the carrier; the first inner electrode is connected to an external power source through a first wire, and the second inner electrode is connected to an external power source through a second wire. The wire is connected to the external power supply;

The balloon is wrapped on the carrier, and an airtight space is formed between the balloon and the carrier, the first inner electrode and the second inner electrode are located in the airtight space, and the airtight space is filled with liquid;

The insulating protective sleeve is sleeved on the carrier and covers the first internal electrode and the second internal electrode; an opening or a slit is formed on the insulating protective sleeve to expose part of the first internal electrode and the second internal electrode; part of the second inner electrode.

Optionally, the carrier is a catheter.

Optionally, the first inner electrode is a positive electrode, and the second inner electrode is a negative electrode; when the shock wave generating device acts on the human blood vessel, under the action of an external power source, the first inner electrode is The liquid is in conduction with the second inner electrode, and the liquid generates air bubbles, so that shock wave energy is generated in the balloon.

Optionally, the number of the first internal electrodes is multiple, and each first internal electrode is a positive electrode, and the second internal electrode is a negative electrode; when the shock wave generating device acts on the human blood vessel, Under the action of an external power source, each first inner electrode is connected to the second inner electrode through a liquid, and the liquid generates air bubbles, so that shock wave energy is generated in the balloon.

Optionally, the first inner electrode is a positive electrode, the number of the second inner electrodes is multiple, and each second inner electrode is a negative electrode; when the shock wave generating device acts on the human blood vessel, Under the action of an external power source, the first inner electrode conducts with each of the second inner electrodes through the liquid, and the liquid generates air bubbles, so that shock wave energy is generated in the balloon.

Optionally, the number of the first internal electrodes is multiple, and the number of the second internal electrodes is multiple; each of the first internal electrodes is a positive electrode, and each of the second internal electrodes is a negative electrode; An inner electrode is arranged corresponding to a second inner electrode; the opposite first inner electrode and the second inner electrode are a group of electrodes.

Optionally, there is an angle difference between each group of electrodes and an adjacent group of electrodes in the direction of the central axis of the carrier, so as to realize spiral discharge.

Optionally, the liquid in the closed space is a mixture of developing solution and physiological saline.

Optionally, the balloon is provided with a plurality of micropores.

According to the specific embodiments provided by the present invention, the present invention discloses the following technical effects:

The first inner electrode and the second inner electrode are respectively arranged on opposite sides of the outer surface of the carrier; and the first inner electrode and the second inner electrode are both connected with an external power source through wires; the balloon is wrapped on the carrier, and the balloon and the carrier are A closed space is formed between them, the first inner electrode and the second inner electrode are located in the closed space, and the closed space is filled with liquid; when the shock wave generating device acts on the human blood vessel, under the action of the external power supply, the first inner electrode The liquid is connected to the second inner electrode, and the liquid generates air bubbles, so that shock wave energy is generated in the balloon, and the calcified tissue at the corresponding position in the blood vessel is broken. Disposing the first inner electrode and the second inner electrode on opposite sides of the outer surface of the carrier improves the efficiency of balloon expansion.

Description of drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the accompanying drawings required in the embodiments will be briefly introduced below. Obviously, the drawings in the following description are only some of the present invention. In the embodiments, for those of ordinary skill in the art, other drawings can also be obtained according to these drawings without creative labor.

1 is a schematic structural diagram of Embodiment 1 of the present invention;

2 is another schematic structural diagram of Embodiment 1 of the present invention;

3 is a schematic structural diagram of Embodiment 2 of the present invention;

4 is a schematic structural diagram of Embodiment 3 of the present invention;

5 is a schematic structural diagram of Embodiment 4 of the present invention;

FIG. 6 is a schematic structural diagram of Embodiment 5 of the present invention.

Symbol Description:

Carrier-1, first inner electrode-2, second inner electrode-3, balloon-4, first wire-5, second wire-6, insulating protective cover-7, opening-8.

Detailed ways

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, but not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

The purpose of the present invention is to provide a shock wave generating device for shaping a cavity in the body. When the shock wave generating device acts on a human blood vessel, under the action of an external power source, the first inner electrode conducts with the second inner electrode through liquid. The calcified tissue at the corresponding position in the blood vessel is broken, and the first inner electrode and the second inner electrode are arranged on the opposite sides of the outer surface of the carrier, which improves the calcification tissue. crushing efficiency.

In order to make the above objects, features and advantages of the present invention more clearly understood, the present invention will be described in further detail below with reference to the accompanying drawings and specific embodiments.

Example 1

As shown in FIG. 1 , the shock wave generating device used for shaping the body cavity of the present invention includes: a carrier 1 , a first inner electrode 2 , a second inner electrode 3 and a balloon 4 .

Wherein, the first inner electrode 2 and the second inner electrode 3 are respectively disposed on opposite sides of the outer surface of the carrier 1 . The first inner electrode 2 is connected to an external power source through a first wire 5 , and the second inner electrode 3 is connected to an external power source through a second wire 6 . Both the first wire 5 and the second wire 6 extend outward along the carrier 1 .

Specifically, the carrier 1 is a catheter. The material of the carrier 1 is an insulating material.

The balloon 4 is wrapped on the carrier 1, and a sealed space is formed between the balloon 4 and the carrier 1. The first inner electrode 2 and the second inner electrode 3 are located in the sealed space, and the The enclosed space is filled with liquid. Specifically, the liquid in the closed space is a mixed liquid of developing solution and physiological saline.

When the shock wave generating device acts on the blood vessels of the human body, under the action of an external power source, the first inner electrode 2 is connected to the second inner electrode 3 through liquid, and the liquid generates air bubbles, so that the Shock wave energy is generated in the balloon 4 . To achieve rapid fragmentation of the calcified tissue at the corresponding position in the blood vessel.

In order to further improve the strength of the shock wave energy, the shock wave generating device for shaping the internal cavity of the present invention further includes an insulating protective cover 7 .

The insulating protective cover 7 is sleeved on the carrier 1 and covers the first inner electrode 2 and the second inner electrode 3 . The insulating protective cover 7 is provided with an opening 8 to expose part of the first inner electrode 2 and part of the second inner electrode 3 . In this embodiment, the opening 8 is an elongated slit. The shape of the insulating protective cover 7 is a pipe material such as a hexagon or an octagon.

By arranging an insulating protective cover between the balloon and the carrier to cover part of the first inner electrode and part of the second inner electrode, so that the current communicates with the fluid only through the opening, the intensity of the shock wave can be increased. Since the shock wave generating device of the present invention is applied to human blood vessels, the overall volume is very small. To ensure the strength of the shock wave, it is necessary to control the areas of the first electrode and the second electrode, thereby increasing the difficulty of electrode preparation. The first inner electrode and part of the second inner electrode are covered, and the current only flows out through the slit, so there is no need to strictly limit the volume of the inner electrode, only the area of the opening of the insulating protective sheath needs to be changed, which reduces the difficulty of preparing the whole shock wave generating device.

In this embodiment, the first inner electrode 2 is a positive electrode, and the second inner electrode 3 is a negative electrode. The direction of current flow is from the first inner electrode 2 to the second inner electrode 3 . Since the first inner electrode 2 and the second inner electrode 3 are located on opposite sides of the carrier 1 , the shock waves generated at both ends of the first inner electrode 2 and the second inner electrode 3 are sent in different directions, which can be applied to intravascular calcification The organization is asymmetrical.

Further, as shown in FIG. 2 , the first inner electrode 2 and the second inner electrode 3 are both electrode sheets.

In order to better inhibit the generation of intravascular calcified tissue, the surface of the balloon 4 can be coated with a medicinal solution for treating intravascular restenosis. In addition, the surface of the balloon 4 can also be coated with paclitaxel, rapamycin or other drugs that can inhibit endothelial hyperplasia.

Preferably, the balloon 4 is an open balloon, that is, the balloon 4 is provided with a plurality of micropores. Due to the small size of the micropores, the surface tension generated by the micropores can maintain a high pressure instantaneously generated in the balloon 4 , thereby causing the balloon 4 to expand rapidly. The drug is delivered to the blood vessel through the open balloon, which can avoid the waste of the drug and reduce the cost.

In this embodiment, the balloon 4 includes an inner layer balloon and an outer layer balloon, and both the inner layer balloon 4 and the outer layer balloon 4 are provided with a plurality of micropores. Furthermore, the balloon 4 may also be in the form of a single leak or a double leak. The number of balloons 4 may also be two or more. When there are two balloons 4 , one balloon 4 may contain developing solution and physiological saline, and the other balloon 4 may be filled with drugs for treating intravascular restenosis.

Example 2

As shown in FIG. 3 , the difference between this embodiment and Embodiment 1 is that the number of the first inner electrodes 2 is multiple. The plurality of first inner electrodes 2 are arranged side by side along the axial direction of the catheter. Each of the first inner electrodes 2 is a positive electrode. The second inner electrode 3 is a negative electrode. The second inner electrodes 3 are arranged on the outer surface of the carrier opposite to the respective first inner electrodes 2 . And the second inner electrode 3 is arranged at a middle position corresponding to the plurality of first inner electrodes 2 . When the shock wave generating device acts on the blood vessels of the human body, under the action of an external power source, each first inner electrode 2 is connected to the second inner electrode 3 through a liquid, and the liquid generates air bubbles, so that the balloon 4 Shock wave energy is generated inside.

Further, the plurality of first inner electrodes 2 are connected in series.

As another embodiment, the first inner electrode 2 includes a plurality of first positive inner electrodes and a plurality of first negative inner electrodes. The plurality of first positive inner electrodes and the plurality of first negative inner electrodes are arranged at intervals along the axial direction of the catheter. The adjacent two first positive inner electrodes and the first negative inner electrodes are a group of electrodes. At this time, the second inner electrode is not energized. Each group of electrodes is connected in parallel. Through the first inner electrode 2 disposed along the axial direction of the carrier, the shock wave generating device generates shock waves on one side of the blood vessel, which is applicable when the calcified tissue in the blood vessel has an asymmetric structure.

Example 3

As shown in FIG. 4 , the difference between this embodiment and Embodiment 1 is that the first inner electrode 2 is a positive electrode; the number of the second inner electrode 3 is multiple. A plurality of second inner electrodes 3 are arranged side by side along the axial direction of the catheter. Each of the second inner electrodes 3 is a negative electrode. The first inner electrodes 2 are arranged on the outer surface of the carrier opposite to the respective second inner electrodes 3 . And the first inner electrode 2 is arranged in the middle position corresponding to the plurality of second inner electrodes 3 . When the shock wave generating device acts on the blood vessels of the human body, under the action of an external power source, the first inner electrode 2 is connected to each second inner electrode 3 through the liquid, and the liquid generates air bubbles, so that the balloon 4 Shock wave energy is generated inside.

Further, the plurality of second inner electrodes 3 are connected in series.

As another embodiment, the second inner electrode 3 includes a plurality of second positive inner electrodes and a plurality of second negative inner electrodes. The plurality of second positive inner electrodes and the plurality of second negative inner electrodes are arranged at intervals along the axial direction of the catheter. The adjacent two second positive inner electrodes and the second negative inner electrodes are a group of electrodes. At this time, the first inner electrode is not energized. Each group of electrodes is connected in parallel. Through the second inner electrode 3 arranged along the axial direction of the carrier, the shock wave generating device can generate shock waves on one side of the blood vessel, which is applicable to the situation where the calcified tissue in the blood vessel has an asymmetric structure.

Example 4

As shown in FIG. 5 , this embodiment combines Embodiment 2 and Embodiment 3. The difference from Embodiment 1 is that the number of the first internal electrodes 2 is multiple, and the second internal electrodes 3 The number is multiple. Each of the first inner electrodes 2 is a positive electrode, and each of the second inner electrodes 3 is a negative electrode. A first inner electrode 2 is arranged corresponding to a second inner electrode 3 . The opposite first inner electrode 2 and second inner electrode 3 are a set of electrodes.

Specifically, a plurality of first internal electrodes 2 are connected in series, and a plurality of second internal electrodes 3 are connected in series. As another embodiment, each set of electrodes is connected in parallel.

When the shock wave generating device acts on the blood vessels of the human body, under the action of an external power source, each first inner electrode 2 conducts with the corresponding second inner electrode 3 through a liquid, and the liquid generates air bubbles, so that the balloon Shock wave energy is generated inside.

Example 5

As shown in FIG. 6 , the difference between this embodiment and Embodiment 5 is that there is an angle difference between each group of electrodes and an adjacent group of electrodes in the direction of the central axis of the carrier, so as to realize spiral discharge. That is, in this embodiment, each group of electrodes is spirally arranged on the carrier, so that the shock wave generated by the shock wave generating device is in a spiral form.

The various embodiments in this specification are described in a progressive manner, and each embodiment focuses on the differences from other embodiments, and the same and similar parts between the various embodiments can be referred to each other.

The principles and implementations of the present invention are described herein using specific examples. The descriptions of the above embodiments are only used to help understand the method and the core idea of the present invention; meanwhile, for those skilled in the art, according to the present invention There will be changes in the specific implementation and application scope. In conclusion, the contents of this specification should not be construed as limiting the present invention.

Claims (9)

1. A shock wave generating device for shaping a cavity in the body, wherein the shock wave generating device for shaping a cavity in the body comprises: a carrier, a first inner electrode, a second inner electrode, an insulating protective sleeve and balloon; The first inner electrode and the second inner electrode are respectively arranged on opposite sides of the outer surface of the carrier; the first inner electrode is connected to an external power source through a first wire, and the second inner electrode is connected to an external power source through a second wire. The wire is connected to the external power supply; The balloon is wrapped on the carrier, and an airtight space is formed between the balloon and the carrier, the first inner electrode and the second inner electrode are located in the airtight space, and the airtight space is filled with liquid; The insulating protective sleeve is sleeved on the carrier and covers the first internal electrode and the second internal electrode; an opening or a slit is formed on the insulating protective sleeve to expose part of the first internal electrode and the second internal electrode; part of the second inner electrode. 2 . The shock wave generating device for shaping an internal cavity according to claim 1 , wherein the carrier is a catheter. 3 . 3 . The shock wave generating device for shaping an internal cavity according to claim 1 , wherein the first inner electrode is a positive electrode, and the second inner electrode is a negative electrode; when the shock wave occurs When the device acts on a human blood vessel, under the action of an external power source, the first inner electrode is connected to the second inner electrode through a liquid, and the liquid generates air bubbles, so that shock wave energy is generated in the balloon. 4 . The shock wave generating device for shaping an internal cavity according to claim 1 , wherein the number of the first inner electrodes is plural, and each first inner electrode is a positive electrode, and the The second inner electrode is a negative electrode; when the shock wave generating device acts on the blood vessels of the human body, under the action of an external power source, each first inner electrode conducts with the second inner electrode through the liquid, and the liquid generates bubbles, Shock wave energy is generated in the balloon. 5 . The shock wave generating device for shaping an internal cavity according to claim 1 , wherein the first inner electrode is a positive electrode, the number of the second inner electrodes is multiple, and each first inner electrode is a positive electrode. 6 . The two inner electrodes are both negative electrodes; when the shock wave generating device acts on the blood vessels of the human body, under the action of an external power source, the first inner electrode conducts with each second inner electrode through the liquid, and the liquid generates bubbles, Shock wave energy is generated in the balloon. 6 . The shock wave generating device for shaping an internal cavity according to claim 1 , wherein the number of the first internal electrodes is plural, and the number of the second internal electrodes is plural; Each of the first inner electrodes is a positive electrode, and each of the second inner electrodes is a negative electrode; a first inner electrode and a second inner electrode are arranged correspondingly; the opposite first inner electrode and second inner electrode are a group of electrodes. 7 . The shock wave generating device for shaping an internal cavity according to claim 1 , wherein each group of electrodes and adjacent groups of electrodes have an angle difference in the direction of the central axis of the carrier to realize spiral discharge. 8 . 8 . The shock wave generating device for shaping a body cavity according to claim 7 , wherein the liquid in the closed space is a mixture of developing solution and physiological saline. 9 . 9 . The shock wave generating device for shaping an internal cavity according to claim 1 , wherein the balloon is provided with a plurality of micro-holes. 10 .

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