CN103239755B - Method for preparing multi-layer composite functional surgical dressing - Google Patents

Abstract

The invention relates to a method for preparing a multi-layer composite functional surgical dressing. The method comprises the following steps: respectively and independently carding the fiber layers comprising a functional layer which is formed by mixing chitosan fiber or chitosan fiber and viscose and is directly contacted with the skin, a water-absorbing layer which is made of viscose and has high liquid absorption performance and a protective layer which is formed by mixing the viscose and polyester fiber and has the supporting and protecting functions so as to form a net, manufacturing a three-layer laminate with an upper functional layer, a middle water-absorbing layer and a lower protective layer by employing a water jet strengthening technology, coating a waterproof agent on the protective layer of the three-layer laminate to form a waterproof layer, and finally rolling to obtain the surgical dressing. The product has high biocompatibility and promotes healing, the antibacterial rate is up to 96.7 percent, the liquid absorption rate is 1259 percent, the waterproofing grade is up to level 5, and the surgical dressing can be used for clinical repair for operative incision, burn, scald, ulcer and other skin injury and is simple in production process, low in cost and environmentally-friendly.

Description

A kind of preparation method of multi-layer composite functional medical dressing

technical field

The invention belongs to the field of medical dressings, in particular to a preparation method of a multilayer composite functional medical dressing.

Background technique

At present, for skin injuries caused by trauma, abrasions, burns, surgical incisions, diabetic ulcers, and varicose ulcers, care products mainly include degreasing gauze, petroleum jelly gauze, saline wet gauze or non-stick film. These sterile products are widely used in the medical industry, but there are some defects: dry gauze is easy to stick to the wound; Damaged, long-term failure to heal, and even secondary infection. In order to make medical dressings have antibacterial properties, scholars at home and abroad have conducted a lot of research, which are summarized as follows:

A composite nano-antibacterial medical dressing (patent CN1537640A), the antibacterial layer is composed of ZnO nanoparticles containing Ag ⁺ on the spunlace non-woven fabric or carbon fiber adsorption material. Comparable comprehensive quality: spectrum, long-term effect, safety, super sterilization, no pollution, convenience, can effectively prevent the invasion of external bacteria, but the cost of preparing nano-silver is very high, and it is not suitable for mass production. A method for preparing a silver ion antibacterial medical dressing (patent CN102600497A) is disclosed, which mixes an antibacterial agent with silver ions and viscose fiber before weaving. The product prepared by this method has a strong anti-infection effect. However, the two methods mentioned in the above patents generally only have antibacterial and antibacterial functions, and are not involved in improving the function of the wound and its surrounding body, accelerating the healing of the wound, and improving the ventilation performance, so the functions are relatively single.

With the improvement of the standards of medical hygiene products, the standardization of the development of medical dressings and the needs of users, the emergence of multifunctional biomedical dressings with hemostasis, antibacterial and good biocompatibility is an urgent need of the medical industry. Chitosan fiber and its products have the functions of antibacterial, hemostasis, promoting healing and analgesia, which can promote the division of various cells such as epithelial cells and fibroblasts and the growth of extracellular matrix, significantly accelerate the healing of wounds, and reduce the Scarring properties, in the medical field, often used as functional dressings.

In recent years, the research on chitosan biological dressings is as follows: a film-shaped or powdered chitosan dressing (patent CN100443123C) is disclosed, which contains chitosan and traditional Chinese medicine extracts or chitosan derivatives or Metal ions, the invented product has the effect of promoting wound healing and hemostasis, and at the same time can inhibit the growth of bacteria, and has good adhesion to the wound, but the membrane-shaped chitosan dressing has airtightness, poor liquid absorption, and no reverse leakage The defect of strength; powdered chitosan medical dressing has good air permeability and good liquid absorption, but it has no covering wound protection effect. A medical colloid dressing with antibacterial and healing-promoting functions (patent CN102335451A). The dressing in the invention is made of water-soluble chitin and methyl biguanide, which has the functions of analgesia, wound healing promotion and bacteriostasis. However, although this product There is a certain amount of liquid absorption, but the liquid absorption is not high.

In order to give full play to the advantages of chitosan medical dressings, some multi-layer composite dressings have appeared, which further make up for the single-function defect of medical dressings on the market. A composite chitosan dressing (patent CN201414876Y), comprising a chitosan material layer, a water-absorbing layer and a backing material layer, and the chitosan material layer is provided with air holes. Although this three-layer composite dressing has good air permeability, It has high liquid absorption performance, prevents reverse leakage, antibacterial, and promotes healing; it relates to a natural medical absorbable biological dressing (CN2400080Y), which uses chitin fiber spunlace cloth as the functional layer, and other non-woven fabric layers as buffer absorption Layer and non-woven fabric with self-adhesive effect are composed of application layer, although compared with ordinary cotton gauze and spunlace non-woven gauze, it has many outstanding advantages such as multi-function and convenient use; a multi-layer composite medical dressing (US005759570A) , the dressing includes an outer protective film, a water-absorbing layer, a molecular filtration membrane, and a wound contact layer. The layers of the composite dressing are bonded by an adhesive, which has limited performance and limited bonding strength, and requires special sizing equipment during use, which limits its use and promotion.

In order to avoid the disadvantages of adhesives, a preparation method of chitin three-layer composite nonwoven fabric (CN102225638A), it is composed of chitin fiber cloth layer, viscose fiber cloth layer and ES fiber cloth layer by acupuncture process, Although it has the functions of hemostasis, antibacterial and high ability to absorb tissue exudate, the acupuncture products have poor softness and poor adhesion to the skin.

To sum up, in order to overcome the single-function defect of existing medical dressings, the research and development of multilayer composite medical dressings and their production and processing technology is still a research hotspot.

Contents of the invention

The technical problem to be solved by the present invention is to provide a preparation method of multilayer composite functional medical dressing. Adding any adhesives or chemical reagents is safe, pollution-free, simple to produce, and low in cost; the multi-layer composite functional medical dressing of the present invention has more comprehensive functions than existing medical dressings, integrates various advantages, and has good Biocompatibility, antibacterial, hemostasis, healing promotion, high moisture absorption, waterproof and other functions, among which the antibacterial rate is as high as 96.7%, the liquid absorption rate is as high as 1259%, and the waterproof level is as high as 5. The product can be widely used for wounds and abrasions , burns, surgical incisions, diabetic ulcers, and varicose ulcers on damaged skin.

A kind of preparation method of multilayer composite functional medical dressing of the present invention comprises:

(1) Mix chitosan fiber and viscose fiber, send them into the cotton storage box, lay them in piles, grab them vertically and send them into the mixing and opening equipment, loosen and dissociate until they are mixed and opened until they are even, then comb, Laying the net to obtain a functional layer web in direct contact with the skin; wherein the weight percentage of chitosan fiber and viscose fiber is (100%-60%): (0%-40%);

(2) Viscose fiber is used, which is sequentially opened, carded and laid to obtain a water-absorbing layer fiber web with better liquid absorption performance;

(3) After mixing the viscose fiber and polyester fiber, loosening, carding, and laying the net in sequence to obtain a protective layer fiber web mixed with viscose and polyester fiber for support and protection; the weight of viscose fiber and polyester fiber The percentage is (50%-0%): (50%-100%);

(4) Laminate in the order of the upper water-absorbing layer fiber web, the middle water-absorbing layer fiber web, and the lower protective layer fiber web, and spunlace the water-entangled machine to obtain a three-layer laminate;

(5) Coat the outer side of the protective layer of the three-layer laminate with a waterproof agent to form a waterproof layer, which is cut and wound to form a multi-layer composite functional medical dressing.

In the step (1), the chitosan fiber has a length of 30mm-60mm and a fineness of 1.7-4.4dtex; the viscose fiber has a length of 35mm-40mm and a fineness of 1.1-2.8dtex; the opening rate is 95%.

The process parameters of carding and web laying in the steps (1)-(3) are: feeding speed of carding machine 0.10-0.50m/min, cylinder speed 600-800m/min, output fiber web speed 30-50m/min, The laying speed is 32-52m/min, the output speed of the bottom curtain is 1.2-10m/min, the laying width is 1.0-2.0m, and the unevenness of the output fiber web is 2.0-4.0%.

In the step (3), the length of the polyester fiber is 30mm-51mm, and the fineness is 1.25-2.65dtex.

In the step (4), pre-wet through the spunlace machine once, spunlace the front side 3 times, and spunlace the back side 2 times.

The spunlace pressure parameters of the spunlace machine are: the pressure of the pre-wet spunlace head is 12-20 Par, the pressure of the main spunlace head 1 ^# is 25-30 Par, the pressure of the main spunlace head 2 ^# is 30-40 Par, and the pressure of the main spunlace head 2 # is 30-40 Par. The pressure of spunlace head 3 ^# is 40-60Par, the pressure of main spunlace head 4 ^# is 45-60Par, the pressure of main spunlace head 5 ^# is 30-45Par, and the production speed of spunlace machine is 2-15m/min .

In the step (5), the process parameters for coating the outer layer of the protective layer with a waterproofing agent to form a waterproofing layer are: the amount of waterproofing agent is 20g/L-30g/L, the amount of liquid is 60%-85%, and the drying temperature is 80°C -120℃, drying time 3min-10min.

In the step (5), the cutting speed is 60-500m/min, the winding diameter is 0.6m-1m/min, and the winding speed is 65-520m/min.

In the medical dressing obtained in the step (5), the functional layer has a grammage of 20-40g/m ² , the water-absorbing layer has a grammage of 40-140g/m ² , and the protective layer has a grammage of 20-40g/m ² .

The surface density of the medical dressing obtained in the step (5) is 80-220g/m ² , and the thickness is 1.40-4.00mm.

The medical dressing obtained in the step (5) has good biocompatibility, hemostatic and healing-promoting effects, the antibacterial rate is as high as 96.7%, the liquid absorption rate is as high as 1259%, and the waterproof grade is between 4-5.

The functional layer made of chitosan fiber or chitosan fiber and viscose fiber mixed in a certain proportion, the water-absorbing layer made of viscose fiber, the protective layer made of viscose fiber and polyester fiber mixed in a certain proportion, each After the fibers of each layer are individually carded into a net, the spunlace reinforcement technology is used to make a three-layer laminate with the upper layer as the functional layer, the middle layer as the water-absorbing layer, and the lower layer as the protective layer, and then the protective layer of the three-layer laminate is coated with waterproofing agent A waterproof layer is formed, and then cut and wound to make multi-layer composite functional medical dressings of required specifications.

A certain amount of chitosan fiber is added to the functional layer of the multi-layer composite functional medical dressing of the present invention in direct contact with the skin; the water-absorbing layer adopts fibers with high-efficiency liquid absorption, and the water-absorbing layer that has absorbed the exudate passes through the functional layer Separate from the wound, avoid direct contact with the wound, and achieve the effect of anti-leakage; the protective layer plays a role of protection and support; the waterproof layer not only ensures the softness of the dressing, but also can well isolate bacteria and moisture from the outside , this multi-layer composite structure integrates various advantages and satisfies the needs of users very well.

The multi-layer composite functional medical dressing has good biocompatibility, hemostasis and healing-promoting effects, the antibacterial rate is as high as 96.7%, the liquid absorption rate is as high as 1259%, and the waterproof grade is between 4 and 5.

Beneficial effect

1. Biocompatibility: Chitosan has a structure similar to cellulose and collagen in animal tissues. In the test, L-929 fibroblasts adhered and proliferated well on the functional layer of the product. Therefore, it has good biocompatibility with the human body and no rejection;

2. Bacteriostasis: The positive charge in the chitosan molecule, the degradation product of chitosan, interacts with the negative charge in the microbial cell membrane, which can form a film on the surface of the bacteria to prevent the entry of nutrients, and chitosan Sugar can pass through the damaged cell membrane and enter the inside of bacteria, inhibit the growth of bacteria by inhibiting the conversion of DNA into RNA, disrupt the synthesis and metabolism of bacteria, and produce antibacterial effects. The verification results show that: the antibacterial rate of the multilayer composite functional medical dressing to Staphylococcus aureus is higher than 93.4%, and the antibacterial rate to Escherichia coli is higher than 86.1%;

3. Hemostasis: The positive charges on the chitosan polymer chain interact with the negatively charged receptors (mainly neuraminic acid residues) on the surface of red blood cells, and at the same time, chitosan plays a certain role in adhesion and aggregation of platelets;

4. Promote skin tissue repair and wound healing: shorten the wound healing time by promoting the migration and expansion of fibroblasts, and accelerate the closure and healing of the wound;

5. High hygroscopicity: The viscose fiber with high-efficiency liquid absorption absorbs exudate, effectively prevents wound effusion infection, and is separated from the wound through the functional layer to avoid direct contact with the wound, keeping the wound clean and non-reverse seepage, The liquid absorption rate of the multi-layer composite functional medical dressing is as high as 1259%;

6. Waterproof: The waterproof agent has good water resistance and impermeability. On the premise of ensuring the softness of the multi-layer composite functional medical dressing, it can well prevent the entry of external bacteria and moisture. The waterproof level is between 4-5 , that is, the surface to be showered is not wetted;

7. The preparation raw materials are easy to obtain and the process is simple. In the production process of the three-layer laminate, only the spunlace process is used for compounding, and no adhesive or chemical reagent is required. It is safe, pollution-free, low-cost, and suitable for mass production;

8. It is widely used and can be used for the repair of skin wounds such as surgical incisions, skin extraction areas, burns, scalds, ulcers or bedsores in clinical practice.

Description of drawings

Fig. 1 is the front view sectional structural schematic diagram of the multilayer composite functional medical dressing of the present invention, wherein, 1-functional layer, 2-absorbent layer, 3-protective layer, 4-waterproof layer;

Fig. 2 is a top view structural diagram of the multilayer composite functional medical dressing shown in Fig. 1, wherein 1 - functional layer, 2 - water absorption layer, 3 - protective layer, 4 - waterproof layer.

Detailed ways

Below in conjunction with specific embodiment, further illustrate the present invention. It should be understood that these examples are only used to illustrate the present invention and are not intended to limit the scope of the present invention. In addition, it should be understood that after reading the teachings of the present invention, those skilled in the art can make various changes or modifications to the present invention, and these equivalent forms also fall within the scope defined by the appended claims of the present application.

Example 1

The preparation method of described multilayer composite functional medical dressing is as follows:

(A) Prepare functional layer 1, adopt 100% chitosan fiber, the length of chitosan is 38mm, the fineness is 1.78dtex, the weight of 1 gram of the functional layer obtained is 40g/m ² , and the fiber raw material is sent into the cotton storage box , laid in piles, vertically grabbed and fed into the BG038 type opening equipment for loosening, dissociation, mixing and opening to uniformity, the resulting opening rate is 95%, and then carded by the BG218 carding machine and laid by a cross-lapper Get functional layer 1 fiber web, specific process parameters: carding machine feeding speed 0.35m/min, cylinder speed 600m/min, output fiber web speed 35m/min, web laying speed 38m/min, bottom curtain output speed 2m/min , The unevenness of the output fiber web is 2.5%.

(B) Prepare the water-absorbing layer 2, adopt 100% viscose fiber, the length of the viscose fiber is 38mm, and the fineness is 1.68dtex ^. Machine opening, BG218 type carding machine carding and cross-lapping machine laying the net to obtain the fiber web of the water-absorbing layer 2. The specific process parameters: the feeding speed of the carding machine is 0.50m/min, the cylinder speed is 800m/min, and the output fiber web speed is 50m/min min, the laying speed is 52m/min, the output speed of the bottom curtain is 8m/min, and the unevenness of the output fiber web is 3%.

(C) prepare protective layer 3, adopt 20/80 viscose fiber/polyester fiber, the length 38mm of viscose fiber, fineness is 1.68dtex, the length 38mm of polyester fiber, fineness is 1.56dtex, the protective layer of gained 3 grams The weight is 40g/m ² , the fiber raw materials are sequentially opened by the BG038 type opener, carded by the BG218 carding machine and laid by a cross-lapper to obtain the fiber web of the protective layer 3. The specific parameters: the feeding speed of the carding machine is 0.35m/ min, cylinder speed 650m/min, output fiber web speed 45m/min, web laying speed 47m/min, bottom curtain output speed 4m/min, output fiber web unevenness 2.8%.

(D) Spunlace compounding, the present invention adopts Fieissner Aquajet Y500-2 type spunlace machine, the prepared functional layer 1 that is in direct contact with the skin, the water-absorbing layer 2 with better liquid absorption performance and the protective layer that plays a supporting and protective role The layer 3 fiber web is laminated in the order of the upper functional layer 1 fiber web, the middle water-absorbing layer 2 fiber web, and the lower protective layer 3 fiber web, and is pre-wetted once by a spunlace machine, spunlaced twice on the front side, and spunlace on the back side twice. , the upper layer is the functional layer 1, the middle layer is the water-absorbing layer 2, and the lower layer is the protective layer 3. The specific process parameters: the pressure of the pre-wet spunlace head is 15Par, and the pressure of the spunlace head is 30Par and 30Par respectively , 40Par, 40Par, the production speed of the spunlace machine is 4m/min.

(E) Apply TG-580 type waterproofing agent on the outside of the protective layer to form a waterproofing layer 4. Specific parameters: the amount of waterproofing agent is 30g/L, the liquid retention rate is 80%, the drying temperature is first 80°C, and drying for 3 minutes. Then dry at 120°C for 3 minutes.

(F) Cutting the multilayer composite functional medical dressing into widths of 7cm, 10cm, 15cm and winding, the cutting speed is 100m/min, the winding diameter is 0.8m/min, and the winding speed is 110m /min.

The multi-layer composite functional medical dressing has good biocompatibility, can quickly promote wound healing, has a bacteriostatic rate higher than 96.7% to Staphylococcus aureus, and has a bacteriostatic rate of 96.7% to Escherichia coli. Higher than 92.8%, the liquid absorption rate is 1259%, and the waterproof level is 5.

Example 2

The preparation method of concrete multilayer composite functional medical dressing is as follows:

(A) prepare functional layer 1, adopt 80/20 chitosan fiber/viscose fiber, the length 38mm of chitosan, fineness is 1.78dtex, the length 38mm of viscose fiber, fineness is 1.68dtex, the function obtained The gram weight of layer 1 is 35g/ ^m2 . The fiber raw materials are sent into the cotton storage box, laid in piles, and vertically grabbed and sent to the BG038 opening equipment for loosening. 95%, after carding by BG218 carding machine and laying by cross-lapper, functional layer 1 fiber web, specific process parameters: carding machine feeding speed 0.40m/min, cylinder speed 700m/min, output fiber web The speed is 48m/min, the laying speed is 50m/min, the output speed of the bottom curtain is 5m/min, and the unevenness of the output fiber web is 2.0%.

(B) Prepare the water-absorbing layer 2, adopt 100% viscose fiber, the length of the viscose fiber is 38mm, and the fineness is 1.68dtex, the weight of the obtained water-absorbing layer 2 is 80g/m ² , and the fiber raw materials are sequentially opened by BG038 type Machine opening, BG218 type carding machine carding and cross-lapping machine laying the net to obtain the fiber web of the water-absorbing layer 2. The specific process parameters: the feeding speed of the carding machine is 0.40m/min, the cylinder speed is 700m/min, and the output fiber web speed is 45m/min min, the laying speed is 48m/min, the output speed of the bottom curtain is 6m/min, and the unevenness of the output fiber web is 3%.

(C) prepare protective layer 3, adopt 30/70 viscose fiber/polyester fiber, the length 38mm of viscose fiber, fineness is 1.68dtex, the length 38mm of polyester fiber, fineness is 1.56dtex, the protective layer of gained 3 grams The weight is 40g/m ² . After the fiber raw materials are evenly mixed, they are sequentially opened by the BG038 type opener, carded by the BG218 carding machine, and laid by a web-laying machine to obtain the fiber web of the protective layer 3. The specific process parameters: Carding machine feeding The speed is 0.45m/min, the cylinder speed is 625m/min, the output fiber web speed is 43m/min, the laying speed is 45m/min, the bottom curtain output speed is 5m/min, and the unevenness of the output fiber web is 2.5%.

(D) Spunlace compounding, the present invention adopts Fieissner Aquajet Y500-2 type spunlace machine, the prepared functional layer 1 that is in direct contact with the skin, the water-absorbing layer 2 with better liquid absorption performance and the protection that plays a supporting and protective role The layer 3 fiber web is laminated in the order of the upper functional layer 1 fiber web, the middle water-absorbing layer 2 fiber web, and the lower protective layer 3 fiber web, and is pre-wetted once by the spunlace machine, 3 times on the front side, and 2 times on the back side. , the upper layer is the functional layer 1, the middle layer is the water-absorbing layer 2, and the lower layer is the protective layer 3. The specific process parameters: the pressure of the pre-wet spunlace head is 15Par, and the pressure of the spunlace head is 30Par and 30Par respectively , 45Par, 45Par, 40Par, the production speed of the spunlace machine is 6m/min.

(E) Apply TG-580 type waterproofing agent on the outside of the protective layer to form a waterproofing layer 4. Specific parameters: the amount of waterproofing agent is 25g/L, the liquid retention rate is 75%, the drying temperature is first 80 ° C, and drying for 3 minutes. Then dry at 120°C for 4 minutes.

(F) Cutting the multilayer composite functional medical dressing into widths of 7cm, 10cm, and 15cm and winding, the cutting speed is 150m/min, the winding diameter is 0.6m/min, and the winding speed is 160m /min.

The multi-layer composite functional medical dressing has good biocompatibility, can quickly promote wound healing, has a bacteriostatic rate higher than 93.7% to Staphylococcus aureus, and has a bacteriostatic rate of 93.7% to Escherichia coli. Higher than 89.8%, the liquid absorption rate is 1057%, and the waterproof level is 5.

Example 3

The preparation method of concrete multilayer composite functional medical dressing is as follows:

(A) prepare functional layer 1, adopt 70/30 chitosan fiber/viscose fiber, the length 38mm of chitosan, fineness is 1.78dtex, the length 38mm of viscose fiber, fineness is 1.68dtex, the function obtained The gram weight of layer 1 is 25g/ ^m2 . The fiber raw materials are sent into the cotton storage box, laid in piles, grabbed vertically and sent to the BG038 type opening equipment for loosening, dissociation, mixing and opening until uniform, and the resulting opening rate 95%, after carding by BG218 carding machine and laying by cross-lapper, the functional layer 1 fiber web is obtained. Specific process parameters: carding machine feeding speed 0.35m/min, cylinder speed 600m/min, output fiber web speed 30m/min, web laying speed 33m/min, bottom curtain output speed 2m/min, unevenness of output fiber web 1.8%.

(B) Prepare the water-absorbing layer 2, adopt 100% viscose fiber, the length of the viscose fiber is 38mm, and the fineness is 1.68dtex, the weight of the obtained water-absorbing layer 2 is 120g/m ² , and the fiber raw materials are sequentially opened by BG038 type Machine opening, BG218 type carding machine carding and cross-lapping machine laying the net to obtain the fiber web of the water-absorbing layer 2. The specific process parameters: the feeding speed of the carding machine is 0.50m/min, the cylinder speed is 800m/min, and the output fiber web speed is 50m/min min, the laying speed is 52m/min, the output speed of the bottom curtain is 8m/min, and the unevenness of the output fiber web is 3%.

(C) prepare protective layer 3, adopt 40/60 viscose fiber/polyester fiber, the length 38mm of viscose fiber, fineness is 1.68dtex, the length 38mm of polyester fiber, fineness is 1.56dtex, the protective layer that obtains 3 grams The weight is 40g/m ² , the fiber raw materials are sequentially opened by the BG038 type opener, carded by the BG218 type carding machine and laid by the web laying machine to obtain the fiber web of the protective layer 3. The specific process parameters: the feeding speed of the carding machine is 0.45m/ min, cylinder speed 650m/min, output fiber web speed 45m/min, web laying speed 48m/min, bottom curtain output speed 6m/min, output fiber web unevenness 3.0%.

(D) Spunlace compounding, the present invention adopts Fieissner Aquajet Y500-2 type spunlace machine, the prepared functional layer 1 that is in direct contact with the skin, the water-absorbing layer 2 with better liquid absorption performance and the protection that plays a supporting and protective role The layer 3 fiber web is laminated in the order of the upper functional layer 1 fiber web, the middle water-absorbing layer 2 fiber web, and the lower protective layer 3 fiber web, and is pre-wetted once by the spunlace machine, 3 times on the front side, and 2 times on the back side. , the upper layer is the functional layer 1, the middle layer is the water-absorbing layer 2, and the lower layer is the protective layer 3. The specific process parameters: the pressure of the pre-wet spunlace head is 15Par, and the pressure of the spunlace head is 30Par, respectively. 30Par, 45Par, 45Par, 40Par, the production speed of the spunlace machine is 4m/min.

(E) Apply TG-580 type waterproofing agent on the outside of the protective layer to form a waterproofing layer 4. Specific parameters: the amount of waterproofing agent is 20g/L, the liquid retention rate is 60%, the drying temperature is 100°C, and drying is 10 minutes.

(F) Cutting the multilayer composite functional medical dressing into widths of 7cm, 10cm, and 15cm and winding, the cutting speed is 200m/min, the winding diameter is 0.8m/min, and the winding speed is 210m /min.

The multi-layer composite functional medical dressing has good biocompatibility, can quickly promote wound healing, has a bacteriostatic rate higher than 90.7% to Staphylococcus aureus, and has a bacteriostatic rate of 90.7% to Escherichia coli. Higher than 85.3%, the liquid absorption rate is 987%, and the waterproof level is 4.

Example 4

The preparation method of concrete multilayer composite functional medical dressing is as follows:

(A) prepare functional layer 1, adopt 60/40 chitosan fiber/viscose fiber, the length 38mm of chitosan, fineness is 1.78dtex, the length 38mm of viscose fiber, fineness is 1.68dtex, the function obtained The weight of layer 1 is 36g/m ² . Send the fiber raw materials into the cotton storage box, lay them in piles, grab them vertically and send them to the BG038 opening equipment for loosening. 95%, after carding by BG218 carding machine and laying by cross-lapper, functional layer 1 fiber web, specific process parameters: carding machine feeding speed 0.35m/min, cylinder speed 650m/min, output fiber web The speed is 38m/min, the laying speed is 40m/min, the output speed of the bottom curtain is 4m/min, and the unevenness of the output fiber web is 2.2%.

(B) Prepare the water-absorbing layer 2, using 100% viscose fiber, the length of the viscose fiber is 38mm, the fineness is 1.68dtex, the weight of the obtained water-absorbing layer is 60g/m ² , and the fiber raw materials are sequentially passed through the BG038 type opener Opening, carding with BG218 carding machine and laying with cross-lapper to obtain water-absorbing layer fiber web. Specific process parameters: carding machine feeding speed 0.24m/min, cylinder speed 600m/min, output fiber web speed 35m/min, The laying speed is 38m/min, the output speed of the bottom curtain is 3m/min, and the unevenness of the output fiber web is 2%.

(C) Prepare protective layer 3, adopt 50/50 viscose fiber/polyester fiber, the length 38mm of viscose fiber, fineness is 1.68dtex, the length 38mm of polyester fiber, fineness is 1.56dtex, the protective layer gram weight of gained The fiber raw material is opened by BG038 type opener, carded by BG218 ^type carding machine and laid by cross-lapper to obtain the protective layer fiber web. Specific process parameters: feeding speed of carding machine 0.40m/min , The cylinder speed is 650m/min, the output fiber web speed is 38m/min, the laying speed is 4m/min, the bottom curtain output speed is 5m/min, and the unevenness of the output fiber web is 3.2%.

(D) Spunlace compounding, the present invention adopts Fieissner Aquajet Y500-2 type spunlace machine, the prepared functional layer 1 that is in direct contact with the skin, the water-absorbing layer 2 with better liquid absorption performance and the protective layer that plays a supporting and protective role The layer 3 fiber web is laminated in the order of the upper functional layer 1 fiber web, the middle water-absorbing layer 2 fiber web, and the lower protective layer 3 fiber web, and is pre-wetted once by the spunlace machine, 3 times on the front side, and 2 times on the back side. , the upper layer is the functional layer 1, the middle layer is the water-absorbing layer 2, and the lower layer is the protective layer 3. The specific process parameters: the pressure of the pre-wet spunlace head is 15Par, and the pressure of the spunlace head is 30Par and 30Par respectively , 45Par, 45Par, 40Par, the production speed of the spunlace machine is 8m/min.

(E) Apply TG-580 type waterproofing agent on the outside of the protective layer to form a waterproofing layer 4. Specific parameters: the amount of waterproofing agent is 30g/L, the liquid retention rate is 70%, the drying temperature is 120°C, and drying is 5 minutes.

(F) Cutting the multilayer composite functional medical dressing into widths of 7cm, 10cm, and 15cm and winding, the cutting speed is 300m/min, the winding diameter is 0.9m/min, and the winding speed is 310m /min.

The multi-layer composite functional medical dressing has good biocompatibility, can quickly promote wound healing, has a bacteriostatic rate higher than 89.4% to Staphylococcus aureus, and has a bacteriostatic rate of 89.4% to Escherichia coli. Higher than 82.5%, the liquid absorption rate is 925%, and the waterproof level is 5.

Claims (10)

1. a preparation method for multi-layer composite functional medical dressing, comprising:

(1) by chitin fiber and viscose rayon mixing, send into cotton storage tank, lay is in heaps, and vertical crawl is sent in mixing opening apparatus, and loosen, dissociation reaches mixing shredding to even, then combing, lapping, obtain functional layer fibre web; Wherein the percentage by weight of chitin fiber, viscose rayon is (100%-60%): (0%-40%); Wherein in functional layer fibre web, the percentage by weight of chitin fiber, viscose rayon is not 100%:0%;

(2) adopt viscose rayon, successively through shredding, combing and lapping, obtain water accepting layer fibre web;

(3) by after viscose rayon and polyster fibre mixing, shredding successively, combing, lapping, obtain protective layer fibre web; Wherein the percentage by weight of viscose rayon, polyster fibre is (50%-0%): (50%-100%); Wherein in protective layer fibre web, the percentage by weight of viscose rayon, polyster fibre is not 0%:100%;

(4) by the order lamination of topmost functional layer fibre web, middle water absorbing layer fibre web, lower floor's protective layer fibre web, through spun-laced machine water thorn, three-layered lamination body is obtained;

(5) outside of the protective layer of three-layered lamination body is coated with waterproofing agent, forms watertight composition, through cutting, reeling, obtain multi-layer composite functional medical dressing.

2. the preparation method of a kind of multi-layer composite functional medical dressing according to claim 1, is characterized in that: in described step (1), the length of chitin fiber is 30mm-60mm, and fineness is 1.7-4.4dtex; The length 35mm-40mm of viscose rayon, fineness is 1.1-2.8dtex; Shredding rate is 95%.

3. the preparation method of a kind of multi-layer composite functional medical dressing according to claim 1, it is characterized in that: in described step (1)-(3), combing and lapping technological parameter are: carding machine feeding speed 0.10-0.50m/min, cylinder speed 600 ~ 800m/min, export web speed 30 ~ 50m/min, lapping speed 32-52m/min, end curtain output speed 1.2-10m/min, lapping width 1.0-2.0m, the irregularity 2.0-4.0% of output fiber net.

4. the preparation method of a kind of multi-layer composite functional medical dressing according to claim 1, is characterized in that: the length 30mm-51mm of polyster fibre in described step (3), fineness is 1.25-2.65dtex.

5. the preparation method of a kind of multi-layer composite functional medical dressing according to claim 1, is characterized in that: prewet 1 time through spun-laced machine in described step (4), front water stings 3 times, and reverse side water stings 2 times.

6. the preparation method of a kind of multi-layer composite functional medical dressing according to claim 1 or 5, is characterized in that: the water thorn pressure parameter of described spun-laced machine is: water jet pressure of prewetting is 12-20Par, main water jet 1 ^#pressure be 25-30Par, main water jet 2 ^#pressure be 30-40Par, main water jet 3 ^#pressure be 40-60Par, main water jet 4 ^#pressure be 45-60Par, main water jet 5 ^#pressure be 30-45Par, the speed of production of spun-laced machine is 2-15m/min.

7. the preparation method of a kind of multi-layer composite functional medical dressing according to claim 1; it is characterized in that: in described step (5), the technological parameter of protective layer skin painting waterproofing agent formation watertight composition is: the consumption of waterproofing agent is 20g/L-30g/L; band liquid measure is 60%-85%; bake out temperature 80 DEG C-120 DEG C, drying time 3min-10min.

8. the preparation method of a kind of multi-layer composite functional medical dressing according to claim 1, it is characterized in that: in described step (5), the speed of cutting is 60-500m/min, winding diameter is 0.6m-1m/min, and winding speed is 65-520m/min.

9. the preparation method of a kind of multi-layer composite functional medical dressing according to claim 1, is characterized in that: in the medical dressing of described step (5) gained, the grammes per square metre of functional layer is 20-40g/m ², the grammes per square metre of water accepting layer is 40-140g/m ², the grammes per square metre of protective layer is 20-40g/m ².

10. the preparation method of a kind of multi-layer composite functional medical dressing according to claim 1, is characterized in that: in described step (5), the surface density of the medical dressing of gained is 80-220g/m ², thickness is 1.40-4.00mm.