CN101869472A - A device for detecting partial myocardial blood flow reserve using a microcatheter - Google Patents
A device for detecting partial myocardial blood flow reserve using a microcatheter Download PDFInfo
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- CN101869472A CN101869472A CN 201010199491 CN201010199491A CN101869472A CN 101869472 A CN101869472 A CN 101869472A CN 201010199491 CN201010199491 CN 201010199491 CN 201010199491 A CN201010199491 A CN 201010199491A CN 101869472 A CN101869472 A CN 101869472A
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- 230000017531 blood circulation Effects 0.000 title claims abstract description 23
- 230000002107 myocardial effect Effects 0.000 title abstract description 3
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- 210000004204 blood vessel Anatomy 0.000 abstract description 4
- 230000008901 benefit Effects 0.000 abstract description 3
- 238000001514 detection method Methods 0.000 abstract description 3
- 238000005259 measurement Methods 0.000 description 13
- 238000000034 method Methods 0.000 description 11
- 231100000915 pathological change Toxicity 0.000 description 11
- 230000036285 pathological change Effects 0.000 description 11
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- 230000003902 lesion Effects 0.000 description 8
- 230000036772 blood pressure Effects 0.000 description 5
- 208000031481 Pathologic Constriction Diseases 0.000 description 4
- 238000004891 communication Methods 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 4
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- 201000000057 Coronary Stenosis Diseases 0.000 description 2
- 208000019802 Sexually transmitted disease Diseases 0.000 description 2
- 238000007887 coronary angioplasty Methods 0.000 description 2
- 210000004351 coronary vessel Anatomy 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 102000029749 Microtubule Human genes 0.000 description 1
- 108091022875 Microtubule Proteins 0.000 description 1
- 150000001336 alkenes Chemical class 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229940127219 anticoagulant drug Drugs 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000009530 blood pressure measurement Methods 0.000 description 1
- 230000008859 change Effects 0.000 description 1
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- 208000029078 coronary artery disease Diseases 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
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- 208000019622 heart disease Diseases 0.000 description 1
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- 210000004688 microtubule Anatomy 0.000 description 1
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Abstract
本发明涉及一种利用微型导管的心肌部分血流储备的检测装置，其特征在于：包含微型导管、外置的测压管、外置的压力换能器以及显示装置；所述微型导管具有管体部，所述管体部具有尖端和尾端；所述管体部内设置有中空的内腔，所述内腔在所述尖端处形成开口；所述尾部处设置有接头，所述测压管通过所述接头与微型导管相连接；所述测压管与压力换能器相连接，压力换能器与显示装置连接。本发明中的所述检测装置由于采用了微型导管，因而能够直接测得血管压力，在评价冠脉内支架置入的即刻效果、指导支架优化置入方面与压力导丝效果相当，但具有操作更为简单、不需反复交换导管、省时、价廉、安全的特点。
The invention relates to a detection device for myocardial partial blood flow reserve using a microcatheter, which is characterized in that it includes a microcatheter, an external pressure measuring tube, an external pressure transducer and a display device; the microcatheter has a tube body, the tube body has a tip and a tail end; a hollow inner cavity is arranged inside the tube body, and an opening is formed in the inner cavity at the tip; a joint is arranged at the tail part, and the pressure measuring The tube is connected with the micro-catheter through the joint; the pressure measuring tube is connected with the pressure transducer, and the pressure transducer is connected with the display device. The detection device in the present invention can directly measure the blood vessel pressure due to the use of a micro-catheter, and is equivalent to the pressure guide wire in terms of evaluating the immediate effect of coronary stent placement and guiding the optimal placement of the stent, but has the advantages of operation It is simpler, does not need to exchange catheters repeatedly, saves time, is cheap, and is safe.
Description
Technical field
The present invention relates to a kind of blood vessel pressure tester, particularly relate to a kind of checkout gear that utilizes the myocardium part blood flow reserve of microguide.
Background technology
Coronarography is the goldstandard of diagnosis heart disease, based on the coronary angioplasty and the Stent of coronary angiography, is the important means of treatment coronary heart disease.
Traditionally, owing to be subjected to blood flow and piezometry technology limitation in the arteria coronaria, get involved the doctor adopts morphological method to judge degree of stenosis more, but this method can't be carried out functional evaluation to pathological changes, and because the defective of coronarography emission image technology, the degree of stenosis that is reflected can not actually reflect the result that postmortem anatomic measurement or IVUS detect.
By the pressure seal wire measure and the calculating myocardium part blood flow reserve (myocardialfractional flow reserve FFRmyo) is the method that the detection arteria coronaria pathological changes physiology a kind of commonly used of developed recently changes.FFRmyo reflects narrow hemodynamics meaning own very specifically, by measuring FFRmyo, can more accurate understanding coronary stricture to the influence degree of myocardial flow, provide reliable foundation to judging whether borderline lesion needs to intervene, simultaneously, can also be used for support and insert therapeutic evaluation afterwards, can reflect the function order of severity that pathological changes is narrow exactly by FFRmyo, help the doctor select more objectively interventional therapy indication, instruct support optimization to insert and judge therapeutic effect and late result.These all gain public acceptance, also have recently and deliver at the randomized controlled trial of FFRmyo specially.Clinically, what application FFRmyo was maximum is that coronary angiography turns out to be the critical stenosis pathological changes, if FFRmyo＜0.75 proves the narrow hematodinamics meaning that has, answers placing rack or row coronary bypass surgery.So the pressure seal wire selects that for the treatment of edge pathological changes certain directive significance is arranged.
FFR is meant the ratio of the far-end blood pressure of the coronary stenosis pathological changes that the pressure seal wire is measured with narrow near-end blood pressure, that is: FFRmyo=Pd/Pa, and wherein, Pd is the far-end blood pressure of the narrow pathological changes of coronary artery, Pa is the near-end blood pressure of the narrow pathological changes of coronary artery.The measurement of the far-end blood pressure of coronary stenosis pathological changes is at present finished by the pressure seal wire.The pressure seal wire is similar to the common seal wire of percutaneous tranluminal coronary angioplasty inch, and the front end of described pressure seal wire is soft head, and the end of this soft head studs with a pressure transducer, and described pressure transducer is positioned at the 3cm place, top of pressure seal wire.The using method of pressure seal wire is: after external zeroing and calibration, after diagnosing or guide wire pressurization pressure seal wire advance people's lesion vessels, make the pressure transducer on it be positioned at the target lesion near-end, this place's guide wire is equated with the pressure of pressure seal wire record, the pressurization pressure seal wire makes its pressure transducer be positioned at the pathological changes far-end by target lesion then, write down the pressure of guide wire and pressure seal wire simultaneously, what the pressure seal wire recorded is the interior pressure of narrow distal vessels, and what guide wire recorded is the interior pressure of narrow nearly distal vessels.
But pressure seal wire of the prior art has following deficiency:
1. Financial cost height.A pressure seal wire price and is disposable use about 10000 yuan, in addition, also needs to be furnished with the pressure display device of expensive special use, and therefore the about 500,000/platform of described display device has increased the input cost of patient's seek medical advice cost and hospital.
2. the real-time pressure value of resulting pressure data of pressure seal wire and indirectly measurement coronary blood flow but value of calculation, thereby can not obtain pressure curve and change.
3. measurement error is big.Because the lesion vessels many places are in tortuous state, so the seal wire in the use is crooked and discounting all can influence certainty of measurement, thereby the build-up of pressure measurement is inaccurate, measurement error is big.
4. complicated operation, the pressure seal wire is difficult for putting in place, needs on the platform under the patient and platform the equipment operator to closely cooperate during measurement and cooperates, and has increased working strength.
Summary of the invention
The purpose of this invention is to provide that a kind of cost is low, the real-time pressure value that can directly measure coronary blood flow and can obtain the checkout gear of that pressure curve changes, certainty of measurement height, easy and simple to handle, the myocardium part blood flow reserve that utilizes microguide that can reduce working strength according to described force value.
For solving the problems of the technologies described above, the present invention takes following technical scheme: a kind of checkout gear that utilizes the myocardium part blood flow reserve of microguide is characterized in that: comprise microguide, external pressure-measuring pipe, external pressure transducer and display device; Described microguide has tube body, and described tube body has tip and tail end; Be provided with the inner chamber of hollow in the described tube body, described inner chamber forms opening at described most advanced and sophisticated place; Described afterbody place is provided with joint, and described pressure-measuring pipe is connected with microguide by described joint; Described pressure-measuring pipe is connected with pressure transducer, and pressure transducer is connected with display device.
The checkout gear of the myocardium part blood flow reserve that utilizes microguide among the present invention is owing to adopted microguide, thereby can directly record vascular pressure, estimating immediate effect that intracoronary stent inserts, instructing support optimization suitable with pressure seal wire effect aspect inserting, operation more simply, does not need repeatedly exchanging pipe, saves time, inexpensive, safe characteristics but have.
Description of drawings
Fig. 1 is the structure chart of the checkout gear of the myocardium part blood flow reserve that utilizes microguide among the present invention.
Fig. 2 utilizes the checkout gear of myocardium part blood flow reserve of microguide and the measurement effect comparison diagram of pressure seal wire.
The specific embodiment
Below in conjunction with accompanying drawing technical scheme of the present invention is elaborated.
Below in conjunction with accompanying drawing technical scheme of the present invention is elaborated.
Fig. 1 shows the structural representation of the checkout gear of the myocardium part blood flow reserve that utilizes microguide among the present invention.As shown in Figure 1, the described checkout gear among the present invention comprises microguide 7, external pressure-measuring pipe 4, external pressure transducer 5 and display device 6.
Described microguide 7 is flexible flexible conduit, and its diameter is less than 3F; Described microguide 7 has tube body 1, and described microtubule body 1 has tip 8 and tail end 9; Be provided with the inner chamber 2 of hollow in the described tube body 1, described inner chamber 2 forms opening at described most advanced and sophisticated 8 places; Described afterbody 9 places are provided with the joint 3 that is connected with described pressure-measuring pipe 4; Described microguide 1 can be adopted as poly-alkene material usually and make, and preferably, it typically has a diameter from about 1.8F-3F.
Described pressure-measuring pipe 4 is connected with pressure transducer 5, and pressure transducer 5 is connected with display device 6.
Described display device 6 is used to read and calculate the measured force value of described pressure transducer 5, it comprise with described pressure transducer 5 between carry out the digital signal acquiring portion that vascular pressure signal transition that the communication section of digital communication maybe can collect pressure transducer mount 5 becomes digital signal, described communication section can directly obtain digitized vascular pressure signal from described pressure transducer 5; In addition, described display device 6 also comprises calculating part, pressure correction portion and pressure display part, described calculating part is the vascular pressure value according to the vascular pressure data reduction that obtains from described pressure transducer 5, described pressure is repaiied described vascular pressure value is revised to obtain more accurate vascular pressure value, described pressure display part with the form of described vascular pressure value by curve in real time, dynamically show through revising, thereby reflect the variation of vascular pressure.Preferably, described calculating display device 6 adopts personal computer to realize.Preferably, described display device 6 also includes control part, and described control part is used to control described communication section or whether digital control signal collection portion carries out work.
The using method of the checkout gear of the myocardium part blood flow reserve that utilizes microguide among the present invention is described below.
Conventional percutaneous puncture, place coronary angiography or guiding catheter, when needs are measured the arteria coronaria internal pressure, behind the inner chamber 2 and pressure-measuring pipe 4 abundant aerofluxuss with microguide, with described 2 and pressure-measuring pipe 4 in be full of the anticoagulant normal saline, again the microguide body is sent in the human body arteria coronaria blood vessel by the sheath pipe; Then, the afterbody of microguide is connected with described pressure-measuring pipe 4 by joint 3, wherein, described pressure-measuring pipe 4 is connected with pressure transducer 5, and pressure transducer 5 is connected with display device 6.
After described microguide is sent into human lesion arteria coronaria blood vessel, described opening by its tip communicates with blood flow in the arteria coronaria, the inner chamber 2 of blood flow by the described normal saline that has been full of of microguide is with described airtight and have the pressure-measuring pipe 4 of normal saline directly to be connected in this moment arteria coronaria, thereby the vascular pressure in the described arteria coronaria can be by described pressure transducer 5 sensings, thereby show in described display device 6.Further, when the microguide tip arrived the near-end of vascular lesion, described display device 6 just began to carry out the vascular pressure monitoring.
The present invention compares with adopting pressure seal wire measurement FFR, and have the following advantages: the blood flow of (1) lesion vessels is by microguide, and pressure-measuring pipe directly links to each other with pressure transducer, directly measures blood stream pressure, and accurately and reliably, the influence factor is few; (2) low price, the about 2000 yuan/root of microguide is equivalent to 1/5 of pressure seal wire, has reduced patient's cost of seeking medical advice; (3) simplify operation technique.Do not comprise seal wire owing to have among the present invention, so avoided the operation of exchange guidewire repeatedly; (4) this pressure measuring system can be monitored the lesion vessels internal pressure in real time in art, be convenient to the patient timely situation in the solving skill; (5) do not need additional in addition special equipment.Above-mentioned pressure-measuring pipe and pressure transducer are conduit room's common equipment, do not need additionally to acquire any equipment, are convenient to promote under the situation that does not increase hospital's input carry out this pressure measuring system; (6) kept the delivery functions of microguide, be particularly suitable for arteria coronaria pressure measxurement and operation technique that the chronic occlusion sexually transmitted disease (STD) becomes, dual-use material reduces medical treatment cost.
Fig. 2 shows the checkout gear of the myocardium part blood flow reserve that utilizes microguide among the present invention and the measurement effect comparison diagram of present UP seal wire.As shown in Figure 2, successively compare with the FFR that microtubular method and pressure seal wire method are measured through routine patient of past 14, visible two kinds of basic zero differences of the resulting FFR of method show the measurement effect that the method can obtain and pressure seal wire effect is identical substantially.In the practice, because the microguide of 2F diameter size is suitable, so can satisfy the measurement requirement of most of arteria coronaria pathological changes.
Among the present invention, microtubular is being estimated immediate effect that intracoronary stent inserts, is being instructed support optimization suitable with the Pressure wire effect aspect inserting, but operate more simple, do not need repeatedly exchanging pipe, save time, inexpensive, safe characteristics, insert immediate effect, instruct support optimization remarkable advantage to be arranged aspect inserting estimating intracoronary stent, be worth in clinical position, applying.
Claims (4)
1. a checkout gear that utilizes the myocardium part blood flow reserve of microguide is characterized in that: comprise microguide, external pressure-measuring pipe, external pressure transducer and display device;
Described microguide has tube body, and described tube body has tip and tail end; Be provided with the inner chamber of hollow in the described tube body, described inner chamber forms opening at described most advanced and sophisticated place;
Described afterbody place is provided with joint, and described pressure-measuring pipe is connected with microguide by described joint;
Described pressure-measuring pipe is connected with pressure transducer, and pressure transducer is connected with display device.
2. the checkout gear that utilizes the myocardium part blood flow reserve of microguide as claimed in claim 1 is characterized in that: the diameter of described microguide is 1.8F-3F.
3. the checkout gear that utilizes the myocardium part blood flow reserve of microguide as claimed in claim 2 is characterized in that: the diameter of described microguide is 2F.
4. as each described checkout gear that utilizes the myocardium part blood flow reserve of microguide of claim 1-3, it is characterized in that: described display device is a computer.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201010199491 CN101869472A (en) | 2010-06-10 | 2010-06-10 | A device for detecting partial myocardial blood flow reserve using a microcatheter |
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| Application Number | Priority Date | Filing Date | Title |
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| CN 201010199491 CN101869472A (en) | 2010-06-10 | 2010-06-10 | A device for detecting partial myocardial blood flow reserve using a microcatheter |
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| CN101869472A true CN101869472A (en) | 2010-10-27 |
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| CN 201010199491 Pending CN101869472A (en) | 2010-06-10 | 2010-06-10 | A device for detecting partial myocardial blood flow reserve using a microcatheter |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019055223A (en) * | 2011-05-27 | 2019-04-11 | ライトラボ・イメージング・インコーポレーテッド | Optical coherence tomography and pressure based system and method |
| CN110269594A (en) * | 2019-06-18 | 2019-09-24 | 济南市第四人民医院 | A kind of coronary flow reserve fraction measurement system |
| CN115813438A (en) * | 2014-11-14 | 2023-03-21 | 皇家飞利浦有限公司 | Percutaneous Coronary Intervention (PCI) planning interface and associated devices, systems, and methods |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1047932A (en) * | 1990-06-02 | 1990-12-19 | 上海长海医院 | Automatic cardiac catheter pressure curve analyzer |
| CN200948136Y (en) * | 2006-03-01 | 2007-09-19 | 四川大学华西医院 | Dynamic monitoring device for abdominal pressure |
| CN201150703Y (en) * | 2007-11-26 | 2008-11-19 | 晏馥霞 | Deep vein duct capable of measuring left atrial pressure |
| CN201691912U (en) * | 2010-06-10 | 2011-01-05 | 杭州市第一人民医院 | A device for detecting partial myocardial blood flow reserve using a microcatheter |
-
2010
- 2010-06-10 CN CN 201010199491 patent/CN101869472A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1047932A (en) * | 1990-06-02 | 1990-12-19 | 上海长海医院 | Automatic cardiac catheter pressure curve analyzer |
| CN200948136Y (en) * | 2006-03-01 | 2007-09-19 | 四川大学华西医院 | Dynamic monitoring device for abdominal pressure |
| CN201150703Y (en) * | 2007-11-26 | 2008-11-19 | 晏馥霞 | Deep vein duct capable of measuring left atrial pressure |
| CN201691912U (en) * | 2010-06-10 | 2011-01-05 | 杭州市第一人民医院 | A device for detecting partial myocardial blood flow reserve using a microcatheter |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019055223A (en) * | 2011-05-27 | 2019-04-11 | ライトラボ・イメージング・インコーポレーテッド | Optical coherence tomography and pressure based system and method |
| US12193789B2 (en) | 2011-05-27 | 2025-01-14 | Lightlab Imaging, Inc. | Optical coherence tomography and pressure based systems and methods |
| CN115813438A (en) * | 2014-11-14 | 2023-03-21 | 皇家飞利浦有限公司 | Percutaneous Coronary Intervention (PCI) planning interface and associated devices, systems, and methods |
| CN110269594A (en) * | 2019-06-18 | 2019-09-24 | 济南市第四人民医院 | A kind of coronary flow reserve fraction measurement system |
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Open date: 20101027 |