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CN109652296A - The bioreactor of removable culture bottle pallet - Google Patents

The bioreactor of removable culture bottle pallet Download PDF

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Publication number
CN109652296A
CN109652296A CN201811359650.XA CN201811359650A CN109652296A CN 109652296 A CN109652296 A CN 109652296A CN 201811359650 A CN201811359650 A CN 201811359650A CN 109652296 A CN109652296 A CN 109652296A
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CN
China
Prior art keywords
culture bottle
connection structure
bioreactor
culture
bottle pallet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201811359650.XA
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Chinese (zh)
Inventor
何加铭
左礼芬
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shanghai Energy Biotechnology Co Ltd
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Shanghai Energy Biotechnology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Energy Biotechnology Co Ltd filed Critical Shanghai Energy Biotechnology Co Ltd
Priority to CN201811359650.XA priority Critical patent/CN109652296A/en
Publication of CN109652296A publication Critical patent/CN109652296A/en
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02Stirrer or mobile mixing elements
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • C12M23/04Flat or tray type, drawers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • C12M23/08Flask, bottle or test tube
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/04Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by injection or suction, e.g. using pipettes, syringes, needles
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/34Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The invention discloses a kind of bioreactors of removable culture bottle pallet, comprising: reaction kettle and host;Reaction kettle is detachably installed to host;Reaction kettle includes: tank body, for accommodating culture solution;And agitating paddle, it is used for stir culture liquid;Host includes: body;Body is formed with the culture bottle platform for placing that can put culture bottle;The bioreactor of removable culture bottle pallet further include: culture bottle pallet;Culture bottle pallet can put several culture bottles;Culture bottle pallet is removably mounted to culture bottle platform for placing;Culture bottle platform for placing is formed with several mounting holes;Culture bottle pallet is equipped with positioning pin;The number of positioning pin is 2;Positioning pin is inserted into mounting hole to fix position of the culture bottle pallet relative to culture solution platform for placing.The bioreactor of removable culture bottle pallet, culture bottle are not easy to fall.

Description

The bioreactor of removable culture bottle pallet
Technical field
The present invention relates to a kind of bioreactors.
Background technique
Pei Yang bottle for accommodating culture solution is generally positioned at the body of bioreactor, when user accidentally touches culture bottle It is easy that culture bottle is made to fall to ground, it may occur however that the case where polluting culture solution or damage culture bottle.
Summary of the invention
To solve the deficiencies in the prior art, the present invention provides a kind of bioreactor of removable culture bottle pallet, cultures Bottle is placed in culture bottle pallet, is not easy to fall.
In order to achieve the above objectives, the present invention adopts the following technical scheme that:
A kind of bioreactor of removable culture bottle pallet, comprising: reaction kettle and host;Reaction kettle is detachably installed to master Machine;Reaction kettle includes: tank body, for accommodating culture solution;And agitating paddle, it is used for stir culture liquid;Host includes: body;It wriggles Pump, for being reaction kettle feed flow;Controller, for controlling peristaltic pump;And stirring motor, for driving agitating paddle to rotate;It wriggles Pump, controller and stirring motor are installed to body;Tank body is detachably installed to body;Body, which is formed with, can put culture bottle Culture bottle platform for placing;The bioreactor of removable culture bottle pallet further include: culture bottle pallet;Culture bottle pallet can be put Several culture bottles;Culture bottle pallet is removably mounted to culture bottle platform for placing;Culture bottle platform for placing is formed with several Mounting hole;Culture bottle pallet is equipped with positioning pin;The number of positioning pin is 2;Positioning pin is inserted into mounting hole with fixed culture Position of the bottle holder disk relative to culture solution platform for placing.
Further, culture bottle pallet includes trying to get to the heart of a matter and around the surrounding tried to get to the heart of a matter and the Pan Bi to raise upward;Pan Bi's is interior Side is perpendicular to the inner surface tried to get to the heart of a matter.
Further, culture bottle platform for placing includes the support plate for being used to support culture bottle pallet;The setting of culture bottle pallet In in support plate.
Further, positioning pin, which is fixed to, tries to get to the heart of a matter and is set to the lower section tried to get to the heart of a matter;Support plate is formed with mounting hole.
Further, the number of mounting hole is more than or equal to the number of positioning pin, and multiple mounting holes arrange along a straight line.
Further, culture bottle platform for placing further includes rear baffle, left baffle and right baffle;Rear baffle, right baffle-plate and the right side Baffle is connected to support plate and upwardly extends;Support plate, rear baffle, left baffle and right baffle surround jointly one it is open forward Space.
Further, agitating paddle is connected with the first connection structure;Stirring motor be connected with for the first connection structure pair The second connection structure connect;When tank body is connect with body, the first connection structure and the docking of the second connection structure are so that stirring motor Drive agitating paddle rotation.
Further, one in the first connection structure and the second connection structure is convex block;First connection structure and second Another in connection structure is the groove that can be inserted into for convex block;When the first connection structure and the second connection structure are docked, Convex block is inserted into groove so that the first connection structure and the second connection structure can rotate synchronously.
Further, host further include: oxygen sensor, for detecting the oxygen in reaction kettle;Temperature sensor is used for Detect the temperature in reaction kettle;With pH sensor, for detecting the pH value in reaction kettle;Oxygen sensor, temperature sensor and PH sensor is detachably connected to tank body.
Further, host further include: air filter, for being filtered to the gas being input in reaction kettle;With Gas-guide tube, for the filtered gas of air filter to be directed into reaction kettle;Gas-guide tube is detachably connected to tank body.
The invention has the beneficial effects that the bioreactor of the removable culture bottle pallet provided, it is fixed that culture bottle pallet passes through With in mounting hole cooperation inserting to culture bottle platform for placing, culture bottle is placed in culture bottle pallet position pin, is not easy to fall.Culture Bottle holder disk is removable easy to clean to remove the culture solution that may be trickled down in culture bottle pallet.
The reaction kettle of bioreactor be removably mounted to body so that bioreactor can be suitably used for it is various types of anti- Kettle is answered, there is versatility, improve the utilization rate of bioreactor.
When reaction kettle is connect with matrix, the docking of the first connection structure and the second connection structure can be realized, so that stirring Motor can drive the intracorporal agitating paddle rotation of tank.
Detailed description of the invention
Fig. 1 is a kind of perspective view of bioreactor of the invention;
Fig. 2 is the perspective view at another visual angle of the bioreactor in Fig. 1;
Fig. 3 is the top view of the bioreactor in Fig. 1;
Fig. 4 is the front view of the bioreactor in Fig. 1;
Fig. 5 is the signal that the first Rack Body of the bioreactor in Fig. 4, the second Rack Body and reaction kettle are separated from each other Figure;
Fig. 6 is the schematic diagram of the part-structure of the bioreactor in Fig. 1;
Fig. 7 is the schematic diagram at another visual angle of the structure in Fig. 6;
Fig. 8 is the agitating paddle of the bioreactor in Fig. 1, the first connection structure, the second connection structure and stirring motor Schematic diagram;
Fig. 9 is the front view of the culture bottle pallet of the bioreactor in Fig. 1;
Figure 10 is the bottom view of the culture bottle pallet in Fig. 9.
Bioreactor 100, reaction kettle 10, tank body 11, agitating paddle 12, the first connection structure 13, the first center line 13a, Host 20, body 21, the first Rack Body 21a, the first electric connection terminal 211a, the second Rack Body 21b, the second electric connection terminal 211b, peristaltic pump 22, controller 23, stirring motor 24, electric machine support 24a, touch control operation display screen 25, air filter 26, Second connection structure 27, the second center line 27a, driving muscle 271, culture bottle platform for placing 28, support plate 281, mounting hole 2811, Culture bottle pallet 29, tries to get to the heart of a matter 291, disk wall 292, positioning pin 30, culture bottle 200.
Specific embodiment
Specific introduce is made to the present invention below in conjunction with the drawings and specific embodiments.
As shown in Figures 1 to 10, a kind of bioreactor 100, comprising: reaction kettle 10 and host 20.Reaction kettle 10 is removable Installation is unloaded to host 20.Reaction kettle 10 includes: tank body 11 and agitating paddle 12.Tank body 11 is for accommodating culture solution.It is being cultivated When culture solution can be delivered in tank body 11 and carry out biological culture.Agitating paddle 12 is used for stir culture liquid.Agitating paddle 12 is to tank body Culture solution in 11 is stirred, and is avoided culture liquid precipitate, so that culture solution is come into full contact with so as to sufficiently react.
Host 20 includes: body 21, peristaltic pump 22, controller 23 and stirring motor 24.Peristaltic pump 22 is used to be reaction kettle 10 feed flows.It is reacted specifically, culture solution is delivered in tank body 11 by peristaltic pump 22.Controller 23 is for controlling peristaltic pump 22.Controller 23 instructs control peristaltic pump 22 to convey culture solution according to the input of user.Stirring motor 24 is for driving agitating paddle 12 rotations.Specifically, agitating paddle 12 is stirred the culture solution in tank body 11 under the driving of stirring motor 24.Host 20 It further include electric machine support 24a.Stirring motor 24 is fixed to electric machine support 24a.
As a kind of specific embodiment, peristaltic pump 22, controller 23 and the installation of stirring motor 24 to body 21.Tank body 11 detachably install to body 21.Agitating paddle 12 is connected with the first connection structure 13.Stirring motor 24 is connected with for first The second connection structure 27 that connection structure 13 is docked.When tank body 11 is connect with body 21, the first connection structure 13 and the second connection Structure 27 is docked so that stirring motor 24 drives agitating paddle 12 to rotate.
Specifically, by the first connection structure 13 of agitating paddle 12 and the second connection structure 27 of stirring motor 24 docking peace Tank body 11 can be installed on body 21 by dress, to be cultivated.First connection structure 13 and the second connection structure 27 can be with structures It is connected at inserting.It, will when needing replacing culture solution culture of the tank body 11 for another different model to be suitable for another scale of construction First connection structure 13 and the separation of the second connection structure 27 can remove tank body 11 to replace the tank body 11 of another different model. Wherein, the culture solution of another scale of construction refers to different for the culture solution of reaction and the volume of the culture solution.A variety of different sizes or The reaction kettle 10 of model can be installed to host 20.
As a preferred embodiment, one in the first connection structure and the second connection structure is convex block.First Another in connection structure and the second connection structure is the groove that can be inserted into for convex block.In the first connection structure 13 and second When connection structure 27 is docked, convex block is inserted into groove so that the first connection structure 13 synchronous can turn with the second connection structure 27 It is dynamic.
Specifically, the first connection structure 13 is groove.Second connection structure 27 is convex block.As a kind of optional implementation Mode, the first connection structure are convex block.Second connection structure is groove.
Tank body 11 is installed on by body 21 using the grafting mounting structure of convex block and groove, structure is simple, high reliablity, and It can guarantee that the first connection structure 13 and the second connection structure 27 rotate synchronously, realize that stirring motor 24 drives agitating paddle 12 to rotate To be stirred to culture solution.
As a preferred embodiment, the definition of the first connection structure 13 has the first center line 13a.Second connection structure 27 definition have the second center line 27a.First connection structure 13 includes several driver slots.Several driver slots are in the first center line It is uniformly distributed in the circumferential direction of 13a.Second connection structure 27 is equipped with multiple driving muscle 271.Multiple driving muscle 271 are in the second center line It is uniformly distributed in the circumferential direction of 27a.When first connection structure 13 and the second connection structure 27 are docked, the first center line 13a and second Center line 27a is overlapped, and driver slot is inserted into driving muscle 271.
Specifically, driver slot is inserted into driving muscle 271 so that by the installation of tank body 11 to body 21, structure is simple, and installation is just It is prompt.Stirring motor 24 drives driving muscle 271 to rotate around the second center line 27a in rotation.Drive muscle 271 by matching with driver slot Crossed belt moves driver slot and rotates around the first center line 13a, that is, drives the rotation of the first connection structure 13 to drive agitating paddle 12 to rotate Realize stirring.
As a kind of specific embodiment, shaft coupling connects the motor shaft and the second connection structure 27 of stirring motor 24. Specifically, shaft coupling is directly connected to the motor shaft and the second connection structure 27 of stirring motor 24.Agitating paddle 12 is fixed to first Connection structure 13.
As a preferred embodiment, the number of driving muscle 271 is greater than the number of driver slot.Specifically, will drive The number of dynamic muscle 271 is set greater than the number of driver slot, convenient for muscle 271 will be driven to be inserted into driver slot.
As a preferred embodiment, the first connection structure 13 is interior flower pattern groove.Second connection structure 27 is ten Font convex block.
Specifically, tank body 11 to be installed on to the side of body 21 using flower pattern groove in being inserted into cross convex block Formula, it is simple and fast, it is easily installed.
As a preferred embodiment, the notch of the top of cross convex block and interior flower pattern groove be equipped with convenient for pair The rounded structure or oblique angle structure connect.
Specifically, rounded structure or oblique angle structure, which can be oriented to cross convex block, is inserted into interior flower pattern groove, so that installation It is more convenient.
As a preferred embodiment, host 20 further include: touch control operation display screen 25.Touch control operation display screen 25 Installation is to body 21, so that user inputs operation instruction or show the relevant information about bioreactor 100.
As a preferred embodiment, host 20 further include: oxygen sensor, temperature sensor and pH sensor. Oxygen sensor is used to detect the oxygen in reaction kettle 10, and the oxygen information that will test is sent to touch control operation display screen 25.Temperature sensor is used to detect the temperature in reaction kettle 10, and the temperature information that will test is sent to touch control operation and shows Screen 25.PH sensor is used to detect the pH value in reaction kettle 10, and the pH value information that will test is sent to touch control operation and shows Screen 25.
As a kind of specific embodiment, oxygen sensor, temperature sensor and pH sensor are detachably connected to Tank body 11 can be disassembled installation to new tank body 11 and continue to detect when in order to replace tank body 11.
As a preferred embodiment, host 20 further include: air filter 26 and gas-guide tube.Air filter 26 For being filtered to the gas being input in reaction kettle 10, the substance of the obstruction reaction in gas is avoided to enter in reaction kettle 10 Influence reaction rate.It is for air guide tube to be directed into reaction kettle 10 in by the filtered gas of air filter 26.
As a kind of specific embodiment, gas-guide tube is detachably connected to tank body 11, will when in order to replace tank body 11 Gas-guide tube disassembles installation to new tank body 11, continues the filtered gas of air filter 26 being directed into new reaction In kettle 10.
As a preferred embodiment, host 20 further include: catheter.Peristaltic pump 22 is led liquid by catheter Enter to reaction kettle 10.As a kind of specific embodiment, catheter is detachably connected to tank body 11, in order to replace tank body Catheter is disassembled into installation to new tank body 11 when 11, continues for the filtered liquid of air filter 26 to be directed into newly Reaction kettle 10 in.
Body 21 includes: the first Rack Body 21a and the second Rack Body 21b.Peristaltic pump 22 and controller 23 are installed to first Rack Body 21a.Stirring motor 24 is installed to the second Rack Body 21b.Tank body 11 is detachably installed to the second Rack Body 21b.Second Rack Body 21b is detachably installed to the first Rack Body 21a.Specifically, the second Rack Body 21b is detachably installed to the first rack Body 21a can disassemble the second Rack Body 21b in transporting biological reactor 100 from the first Rack Body 21a.In this way Convenient for the transport of bioreactor 100.
The bottom of first Rack Body 21a and the second Rack Body 21b are equipped with support wheel.User can push the second Rack Body 21b moves the assembling for realizing the first Rack Body 21a and the second Rack Body 21b relative to the first Rack Body 21a.
As a preferred embodiment, the first Rack Body 21a is equipped with: the first electric connection terminal 211a.Second rack Body 21b is equipped with: the second electric connection terminal 211b.Second electric connection terminal 211b is electrically connected to stirring motor 24.First electrical connection Terminal 211a is electrically connected to the power supply powered for stirring motor 24.Second Rack Body 21b is connect with the first Rack Body 21a When, the first electric connection terminal 211a is electrically connected to enable power supply for stirring electricity with the second electric connection terminal 211b composition Machine 24 is powered.
Specifically, the first electric connection terminal 211a is arranged in the first Rack Body 21a, in the second Rack Body 21b setting the Two electric connection terminal 211b, when the second Rack Body 21b is connect with the first Rack Body 21a, the first electric connection terminal 211a and Two electric connection terminal 211b constitute electrical connection to enable power supply for the power supply of stirring motor 24.Setting is avoided in machine in this way A plurality of cable electrical connection power supply and stirring motor 24 are set outside body 21, to avoid being located at the cable outside body 21 Line loss badly causes installation problems.Meanwhile it being connect by the second Rack Body 21b with the first Rack Body 21a and can realize that first is electrically connected The electric connection of connecting terminal 211a and the second electric connection terminal 211b, structure is simple, easy for installation.
As a preferred embodiment, the second electric connection terminal 211b inserting relative to the first electric connection terminal 211a Pull out installation direction of the direction perpendicular to tank body 11 relative to the second Rack Body 21b.
As a preferred embodiment, tank body 11 relative to the second Rack Body 21b installation direction perpendicular to second Installation direction of the Rack Body 21b relative to the first Rack Body 21a.
As a preferred embodiment, the second Rack Body 21b is vertical relative to the installation direction of the first Rack Body 21a In the pivot center of agitating paddle 12.
As a preferred embodiment, touch control operation display screen 25 is installed to the first Rack Body 21a.As a kind of excellent The embodiment of choosing, detachably installation carries out more air filter 26 to the first Rack Body 21a air filter 26 It changes.
As a preferred embodiment, the second Rack Body 21b is formed far from one end of the first Rack Body 21a to separate The arcuate structure of the side protrusion of first Rack Body 21a.
As a preferred embodiment, the upper surface of one end far from the first Rack Body 21a of the second Rack Body 21b It constitutes semicircle.
Specifically, setting semicircle for the upper surface of one end far from the first Rack Body 21a of the second Rack Body 21b Shape, second Rack Body 21b will not generate interference to user when convenient for the user to operate.
Body 21 is formed with the culture bottle platform for placing 28 that can put culture bottle 200.Culture solution is being supplied into tank body When, culture bottle 200 can be placed in culture bottle platform for placing 28.The two sides of body 21 are equipped with culture bottle platform for placing 28. Platform for placing is set to the lower section of peristaltic pump, helps to shorten feed flow path, reduces the requirement to wriggling pump power.
The bioreactor 100 of removable culture bottle pallet 29 further include: culture bottle pallet 29.Culture bottle pallet 29 can be put Put several culture bottles 200.Culture bottle pallet 29 is detachably installed and culture bottle platform for placing 28.
Culture bottle platform for placing 28 is formed with several mounting holes 2811.Culture bottle pallet is equipped with positioning pin 30.Positioning Pin 30 is inserted into mounting hole 2811 to fix position of the culture bottle pallet 29 relative to culture solution platform for placing.Specifically, The number of positioning pin 30 is 2.
As a preferred embodiment, culture bottle pallet 29 include try to get to the heart of a matter 291 and around try to get to the heart of a matter 291 surrounding and to The disk wall 292 of upper protrusion.The medial surface of disk wall 292 perpendicular to try to get to the heart of a matter 291 inner surface.Disk wall 292 can be avoided culture bottle from Culture bottle pallet 29 is detached from.
Culture bottle platform for placing 28 includes the support plate 281 for being used to support culture bottle pallet 29.Culture bottle pallet 29 is arranged In in support plate 281.Positioning pin 30 be fixed to try to get to the heart of a matter 291 and be set to try to get to the heart of a matter 291 lower section.Support plate 281 is formed with installation Hole 2811.The number of mounting hole 2811 is more than or equal to the number of positioning pin 30, and multiple mounting holes 2811 arrange along a straight line.It is multiple Mounting hole 2811 equidistantly arranges.As a kind of specific embodiment, the number of mounting hole 2811 is 3.Culture bottle pallet 29 Two culture bottles 200 can be accommodated.
Specifically, culture bottle platform for placing 28 further includes rear baffle, left baffle and right baffle.Rear baffle, right baffle-plate and Right shell body is connected to support plate 281 and upwardly extends.Support plate 281, rear baffle, left baffle and right baffle surround jointly one to Culture bottle pallet 29 and culture bottle 200 are taken out to facilitate in preceding open space.Touch control operation display screen 25 is put positioned at culture bottle The top of platform 28.
The basic principles, main features and advantages of the invention have been shown and described above.The technical staff of the industry should Understand, the above embodiments do not limit the invention in any form, all obtained by the way of equivalent substitution or equivalent transformation Technical solution is fallen within the scope of protection of the present invention.

Claims (10)

1. a kind of bioreactor of removable culture bottle pallet characterized by comprising reaction kettle and host;The reaction kettle It is detachable to install to the host;
The reaction kettle includes:
Tank body, for accommodating culture solution;With
Agitating paddle is used for stir culture liquid;
The host includes:
Body;
Peristaltic pump, for being the reaction kettle feed flow;
Controller, for controlling the peristaltic pump;With
Stirring motor, for driving the agitating paddle to rotate;
The peristaltic pump, the controller and the stirring motor are installed to the body;The tank body is detachably installed to institute State body;The body is formed with the culture bottle platform for placing that can put culture bottle;The biology of the removable culture bottle pallet Reactor further include: culture bottle pallet;The culture bottle pallet can put several culture bottles;The culture bottle pallet is removable It unloads and is installed on the culture bottle platform for placing;The culture bottle platform for placing is formed with several mounting holes;The culture bottle holder Disk is equipped with positioning pin;The number of the positioning pin is 2;
The positioning pin is inserted into the mounting hole with the fixation culture bottle pallet relative to the culture solution platform for placing Position.
2. the bioreactor of removable culture bottle pallet according to claim 1, which is characterized in that
The culture bottle pallet includes trying to get to the heart of a matter and around the surrounding tried to get to the heart of a matter and the Pan Bi to raise upward;The inside of the Pan Bi Face is perpendicular to the inner surface tried to get to the heart of a matter.
3. the bioreactor of removable culture bottle pallet according to claim 2, which is characterized in that
The culture bottle platform for placing includes the support plate for being used to support the culture bottle pallet;
The culture bottle pallet is set in the support plate.
4. the bioreactor of removable culture bottle pallet according to claim 3, which is characterized in that
The positioning pin, which is fixed to, described try to get to the heart of a matter and is set to the lower section tried to get to the heart of a matter;The support plate is formed with the installation Hole.
5. the bioreactor of removable culture bottle pallet according to claim 1, which is characterized in that
The number of the mounting hole is more than or equal to the number of the positioning pin, and multiple mounting holes arrange along a straight line.
6. the bioreactor of removable culture bottle pallet according to claim 3, which is characterized in that
The culture bottle platform for placing further includes rear baffle, left baffle and right baffle;The rear baffle, the right baffle-plate and described Right shell body is connected to the support plate and upwardly extends;The support plate, the rear baffle, the right baffle-plate and the right shell body An open space forward is surrounded jointly.
7. the bioreactor of removable culture bottle pallet according to claim 1, which is characterized in that
The agitating paddle is connected with the first connection structure;The stirring motor is connected with for docking with first connection structure The second connection structure;When the tank body is connect with the body, first connection structure and second connection structure pair It connects so that the stirring motor drives the agitating paddle rotation.
8. the bioreactor of removable culture bottle pallet according to claim 7, which is characterized in that
One in first connection structure and second connection structure is convex block;First connection structure and described Another in two connection structures is the groove that can be inserted into for the convex block;Connect in first connection structure and described second When binding structure docks, the convex block is inserted into the groove so that first connection structure and the second connection structure energy It is enough to rotate synchronously.
9. the bioreactor of removable culture bottle pallet according to claim 1, which is characterized in that
The host further include:
Oxygen sensor, for detecting the oxygen in the reaction kettle;
Temperature sensor, for detecting the temperature in the reaction kettle;With
PH sensor, for detecting the pH value in the reaction kettle;
The oxygen sensor, the temperature sensor and the pH sensor are detachably connected to the tank body.
10. the bioreactor of removable culture bottle pallet according to claim 1, which is characterized in that
The host further include:
Air filter, for being filtered to the gas being input in the reaction kettle;With
Gas-guide tube, for the filtered gas of the air filter to be directed into the reaction kettle;
The gas-guide tube is detachably connected to the tank body.
CN201811359650.XA 2018-11-15 2018-11-15 The bioreactor of removable culture bottle pallet Pending CN109652296A (en)

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Citations (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102296029A (en) * 2010-06-28 2011-12-28 裴国献 perfusion bioreactor system
CN102382766A (en) * 2011-11-29 2012-03-21 向开兴 Tidal bioreactor for animal cell culture
CN103160435A (en) * 2011-12-14 2013-06-19 西安瑞捷生物科技有限公司 Bioreactor for tissue engineering products
CN203565000U (en) * 2013-11-05 2014-04-30 东莞市知力自动化设备有限公司 Fluid matching stirring machine
US20150353879A1 (en) * 2014-06-05 2015-12-10 Taiwan Leader Biotech Corp. Omni-functional high-efficient solid-state fermentation method for edible and medicinal microorganisms
CN204951465U (en) * 2015-09-23 2016-01-13 丽水市人民医院 Medical nursing vehicle
CN204991997U (en) * 2015-06-30 2016-01-20 国家电网公司 Power cable connecting terminal sub -assembly
CN205794399U (en) * 2016-05-15 2016-12-14 福建金草生物集团股份有限公司 A kind of Herba Anoectochili roxburghii culturing rack
CN206121658U (en) * 2016-10-17 2017-04-26 江西惟庭实业有限公司 Feed additive mixer is easily washd to high efficiency
CN107416969A (en) * 2017-05-16 2017-12-01 西安建筑科技大学 A kind of on-line automatic regulation and control pH bioreactor and its regulation and control method
CN206751816U (en) * 2016-11-22 2017-12-15 江南大学 A kind of parallel multi-joint fermentation tank
CN207575062U (en) * 2017-05-25 2018-07-06 四川省志强泡海椒有限责任公司 A kind of household pickle jar
CN207667688U (en) * 2017-11-28 2018-07-31 杨芳 A kind of chemistry container rack
CN207828254U (en) * 2017-12-16 2018-09-07 山东新华医疗器械股份有限公司 Split type parallel bioreactor
CN207987173U (en) * 2018-01-03 2018-10-19 北京希普惠达饲料有限公司 A kind of fermentation tank equipped with air filter

Patent Citations (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102296029A (en) * 2010-06-28 2011-12-28 裴国献 perfusion bioreactor system
CN102382766A (en) * 2011-11-29 2012-03-21 向开兴 Tidal bioreactor for animal cell culture
CN103160435A (en) * 2011-12-14 2013-06-19 西安瑞捷生物科技有限公司 Bioreactor for tissue engineering products
CN203565000U (en) * 2013-11-05 2014-04-30 东莞市知力自动化设备有限公司 Fluid matching stirring machine
US20150353879A1 (en) * 2014-06-05 2015-12-10 Taiwan Leader Biotech Corp. Omni-functional high-efficient solid-state fermentation method for edible and medicinal microorganisms
CN204991997U (en) * 2015-06-30 2016-01-20 国家电网公司 Power cable connecting terminal sub -assembly
CN204951465U (en) * 2015-09-23 2016-01-13 丽水市人民医院 Medical nursing vehicle
CN205794399U (en) * 2016-05-15 2016-12-14 福建金草生物集团股份有限公司 A kind of Herba Anoectochili roxburghii culturing rack
CN206121658U (en) * 2016-10-17 2017-04-26 江西惟庭实业有限公司 Feed additive mixer is easily washd to high efficiency
CN206751816U (en) * 2016-11-22 2017-12-15 江南大学 A kind of parallel multi-joint fermentation tank
CN107416969A (en) * 2017-05-16 2017-12-01 西安建筑科技大学 A kind of on-line automatic regulation and control pH bioreactor and its regulation and control method
CN207575062U (en) * 2017-05-25 2018-07-06 四川省志强泡海椒有限责任公司 A kind of household pickle jar
CN207667688U (en) * 2017-11-28 2018-07-31 杨芳 A kind of chemistry container rack
CN207828254U (en) * 2017-12-16 2018-09-07 山东新华医疗器械股份有限公司 Split type parallel bioreactor
CN207987173U (en) * 2018-01-03 2018-10-19 北京希普惠达饲料有限公司 A kind of fermentation tank equipped with air filter

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