CN108744113B - Automatic synthetic contrast agent and injection device - Google Patents
Automatic synthetic contrast agent and injection device Download PDFInfo
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- CN108744113B CN108744113B CN201810646005.XA CN201810646005A CN108744113B CN 108744113 B CN108744113 B CN 108744113B CN 201810646005 A CN201810646005 A CN 201810646005A CN 108744113 B CN108744113 B CN 108744113B
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- locking device
- contrast agent
- air
- injector
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- 239000002872 contrast media Substances 0.000 title claims abstract description 64
- 238000002347 injection Methods 0.000 title claims abstract description 46
- 239000007924 injection Substances 0.000 title claims abstract description 46
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 45
- 239000002504 physiological saline solution Substances 0.000 claims description 38
- 229910052742 iron Inorganic materials 0.000 claims description 23
- 238000001514 detection method Methods 0.000 claims description 22
- 238000003825 pressing Methods 0.000 claims description 12
- 239000007788 liquid Substances 0.000 claims description 11
- 238000009434 installation Methods 0.000 claims description 4
- 230000004087 circulation Effects 0.000 claims description 3
- 238000002156 mixing Methods 0.000 abstract description 7
- 230000001737 promoting effect Effects 0.000 abstract 1
- 238000001802 infusion Methods 0.000 description 10
- 238000000034 method Methods 0.000 description 9
- 238000002601 radiography Methods 0.000 description 8
- 230000000903 blocking effect Effects 0.000 description 7
- 238000007689 inspection Methods 0.000 description 6
- 230000008569 process Effects 0.000 description 6
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 5
- 239000000284 extract Substances 0.000 description 4
- 230000009471 action Effects 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 230000002526 effect on cardiovascular system Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 238000005452 bending Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 230000000747 cardiac effect Effects 0.000 description 2
- 210000000748 cardiovascular system Anatomy 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000006073 displacement reaction Methods 0.000 description 2
- 238000010253 intravenous injection Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000010355 oscillation Effects 0.000 description 2
- 238000009423 ventilation Methods 0.000 description 2
- 230000004075 alteration Effects 0.000 description 1
- 210000003484 anatomy Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 238000013155 cardiography Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000002592 echocardiography Methods 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 238000012285 ultrasound imaging Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/007—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests for contrast media
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/1407—Infusion of two or more substances
- A61M5/1408—Infusion of two or more substances in parallel, e.g. manifolds, sequencing valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/16804—Flow controllers
- A61M5/16827—Flow controllers controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The invention relates to the technical field of medical equipment, and discloses an automatic synthetic contrast agent and an injection device, wherein the technical problems of insufficient mixing times of the contrast agent and poor stability of microbubbles are solved by arranging a first air pump, a second air pump, a first electromagnetic air valve and a second electromagnetic air valve, and converting the structural connection between the first air cylinder and the second air cylinder into the automatic contrast injection device by a traditional manually operated contrast injector; through realizing automation and standardization of the examination, the mixing frequency and the times of the contrast agent are accurately mastered, meanwhile, the size of the contrast agent microbubbles in the injector is uniform and more stable, the influences of frequency substandard and insufficient times during manual operation are made up, thereby improving the accuracy and repeatability of the contrast examination, reducing the difference of examination results caused by different operators, improving the examination efficiency, reducing the cost of human resources and promoting the popularization and application of examination items in clinic.
Description
Technical Field
The invention relates to the technical field of medical equipment, in particular to an automatic synthetic contrast agent and an injection device.
Background
Heart color ultrasound imaging is based on conventional echocardiography, and certain substances (contrast agents) capable of changing the ultrasound image of the cardiovascular system enter the cardiovascular part through various ways to generate imaging effect. When the acoustic contrast agent containing the microbubbles enters the blood, the very obvious acoustic impedance difference between the microbubbles and the blood forms strong ultrasonic reflection, so that the cardiovascular blood flow without obvious echo reflection is visualized, and new information is provided for determining the anatomical structure of the cardiovascular system, cardiovascular shunt or reflux lesion and the like.
Nowadays, the radiography technology can be applied to various fields, but the current cardiac radiography inspection project technology is mainly manually operated and adopts 2 10ml syringes and three-way switch connection; the injector is manually pushed back and forth for 20 times (one push-out is repeatedly recorded as one hand vibration, the pushing frequency is about 80 times/min), the manual operation is performed to mix the contrast agent, the efficiency is low, the workload of medical operators is large, the manpower resource cost is high, the injector is easily limited by factors such as the technical proficiency of operators, and the like, different operators can have different contrast effects due to different speed and times when the operators shake to mix the contrast agent, different injection speeds, injection delay and the like, the result repeatability is poor, and the technology is difficult to popularize widely in clinic because the standardization cannot be achieved.
Disclosure of Invention
(one) solving the technical problems
Aiming at the defects of the prior art, the invention provides an automatic synthesis contrast agent and an injection device, which have the advantages of automatically synthesizing the contrast agent, injecting the contrast agent into a patient and the like, and solve the problems that the traditional contrast injector can only synthesize the contrast agent microbubbles by manually operating two injectors, so that the mixing degree of the contrast agent is difficult to master, certain deviation is caused to a contrast examination result, the workload of medical operators is large, and the popularization is difficult.
(II) technical scheme
In order to achieve the above purpose, the present invention provides the following technical solutions: an automated synthetic contrast agent and injection device, comprising: a bottom plate, a bearing seat, a sliding rail, a first injector, a second injector, a limit sleeve, a first cylinder, a four-way joint and a controller,
the top of the bottom plate is provided with a first fixing seat and a second fixing seat, the top of the first fixing seat is provided with an arc groove, a mounting hole and a limiting groove, the top of the second fixing seat is also provided with an arc groove, a mounting hole and a limiting groove, and the upper surface of the second fixing seat and the bottom plate are designed in an inclined way; the bearing seat is arranged on the right side of the first fixing seat, and is provided with a bearing cavity and a through groove; the sliding rail is characterized in that a fixed block is arranged on one side of the sliding rail, the other end of the fixed block is connected with a second spring, the other end of the second spring is connected with a sliding block, a movable locking block is arranged at the top of the sliding block, an electromagnet is arranged in the movable locking block and is pressed through a rear plate, an iron block is arranged on the other side of the sliding rail, and a bearing step is arranged in the middle of the iron block; the first syringe barrel is arranged in an arc groove at the top of the first fixing seat, and the top of the first syringe barrel is embedded into the limit groove; the second syringe barrel is arranged in the circular arc groove at the top of the second fixing seat, and the top of the second syringe barrel is inlaid in the limit groove; a clamping block is arranged in the limiting sleeve, a connecting pipe is arranged at the bottom of the limiting sleeve, a needle head is arranged at the top of the connecting pipe, a bearing cavity in the limiting sleeve is used for loading the physiological saline bottle, a bayonet of the physiological saline bottle is clamped through the clamping block, and the needle head at the top of the connecting pipe is inserted into the physiological saline bottle; the first push rod of the first air cylinder is connected with the clamping plate, and the first piston handle matched with the first injector is clamped in the clamping plate; the four-way joint is characterized in that four external interfaces are respectively connected with a first hose, a second hose, a third hose and a fourth hose, the other end of the first hose is connected with an injection end of a first syringe, the second hose is externally connected with an infusion tube, the third hose is connected with a connecting tube, the fourth hose is connected with an injection end of a second syringe, a first locking device, a second locking device, a third locking device and a fourth locking device are respectively arranged at the first hose, the second hose, the third hose and the fourth hose, and a blockage detection device is arranged at the outer side of the second locking device to detect blockage of output liquid of the second hose; the signal output end of the controller is respectively connected with the signal input ends of the first electromagnetic valve, the second electromagnetic valve, the first locking device, the second locking device, the third locking device and the fourth locking device.
Preferably, the first locking device consists of a movable locking block and an iron block, the electromagnet arranged in the movable locking block is electrified and strongly adsorbed with the iron block, so that the first hose is clamped, the liquid circulation is blocked, the principles of the second locking device, the third locking device and the fourth locking device are consistent with those of the first locking device, and the second hose, the third hose and the fourth hose can be respectively controlled to be clamped.
Preferably, one side of the movable locking block, which is close to the first hose, is in an arc convex shape, and one side of the iron block, which is close to the first hose, is in an arc concave shape.
Preferably, the first movable clamping piece and the second movable clamping piece are arranged at the positions Bie An of the mounting holes at the tops of the first fixing seat and the second fixing seat, the first movable clamping piece and the second movable clamping piece are fixed on the first fixing seat and the second fixing seat through equal-height screws, and a first spring is arranged between the boss of the equal-height screws and the interiors of the first movable clamping piece and the second movable clamping piece, so that the first movable clamping piece and the second movable clamping piece can stretch elastically up and down and rotate along the axis of the equal-height screws, the tops of the first movable clamping piece and the second movable clamping piece are arc-shaped, and the diameter of the arc is equal to that of the first injector and the second injector.
Preferably, the first air cylinder air source input end is connected with the first electromagnetic valve air outlet end through the air pipe, the first electromagnetic valve air inlet end is connected with the first air pump air outlet end through the air pipe, the second air cylinder air source input end is connected with the second electromagnetic valve air outlet end through the air pipe, and the second electromagnetic valve air inlet end is connected with the second air pump air outlet end through the air pipe.
Preferably, the first electromagnetic valve and the second electromagnetic valve are five-position three-way electromagnetic valves.
Preferably, the controller power input end is electrically connected with the storage battery power output end, and the controller signal input end is in signal connection with the operation button at the top of the shell.
Preferably, the shell is fixed at the top of the bottom plate through bolt installation, the rear side of the shell is provided with a vent hole and an external power hole, and the front side of the shell is provided with a through hole.
Preferably, the top of the blockage detection device is provided with a pressing plate, the pressing plate is connected with the blockage detection device through a hinge, the other side of the pressing plate is provided with a fastener for clamping a clamping groove on one side of the blockage detection device, and the signal output end of the blockage detection device is connected with the signal input end of the controller.
Preferably, the inclination angle between the upper surface of the second fixing seat and the bottom plate is 35-45 degrees.
(III) beneficial effects
Compared with the prior art, the invention provides an automatic synthetic contrast agent and an injection device, which have the following beneficial effects:
this automatic change synthetic contrast agent and injection device through setting up the structural connection between first air pump, second air pump, first electromagnetic valve, second electromagnetic valve and first cylinder, the second cylinder, by traditional manual operation contrast syringe conversion to automatic contrast injection device, solved original operation oscillation frequency not up to standard, mix the number of times not enough, medical personnel work load technical problem such as big.
Through realizing automation and standardization of the examination, the mixing frequency and the times of the contrast agent are accurately mastered, meanwhile, the size of the contrast agent microbubbles in the injector is also uniform, and the influences of frequency substandard and insufficient times in manual operation are made up, so that the accuracy and repeatability of the contrast examination are improved, the difference of examination results caused by different operators is reduced, the examination efficiency is improved, the human resource cost is reduced, and the popularization and application of examination items in clinic are promoted.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate and together with the embodiments of the invention and do not constitute a limitation to the invention, and in which:
FIG. 1 is a schematic diagram of the overall structure of the present invention;
FIG. 2 is a schematic diagram of the internal structure connection of the present invention;
FIG. 3 is a schematic view of the structure of the base plate of the present invention;
FIG. 4 is a schematic view of the positioning of four locking devices according to the present invention;
FIG. 5 is a schematic view showing the connection of the first locking device to the first hose structure according to the present invention;
FIG. 6 is a schematic view of a first locking device according to the present invention;
FIG. 7 is a schematic view of a first movable clip according to the present invention;
FIG. 8 is a cross-sectional view of a saline bottle and a stop sleeve of the present invention;
FIG. 9 is a cross-sectional view of a spacing sleeve of the present invention;
FIG. 10 is a schematic view of a physiological saline bottle according to the present invention;
FIG. 11 is a cross-sectional view of a load bearing chamber of the present invention;
FIG. 12 is a schematic view of a second hose connection to a occlusion detection device according to the present invention;
FIG. 13 is a cross-sectional view of an occlusion detection device of the present invention;
FIG. 14 is a top view of the internal structure of the present invention;
FIG. 15 is a schematic view of the housing structure of the present invention;
FIG. 16 is a flow chart of the present invention.
In the figure: 1-bottom plate, 2-housing, 3-bearing seat, 31-bearing cavity, 32-through slot, 4-first fixing seat, 41-circular arc groove, 42-mounting hole, 43-limit slot, 5-second fixing seat, 6-blocking detection device, 61-clamping slot, 62-pressing plate, 63-fastener, 64-guide rod, 65-guide spring, 66-movable cavity, 67-pressure sensor, 68-circuit board, 7-first injector, 71-first piston handle, 72-first piston rod, 8-second injector, 81-second piston handle, 82-second piston rod, 9-first movable clamping piece, 91-equal height screw, 92-first spring, 10-second movable clamping piece, 11-slide rail 111-fixed block, 112-second spring, 113-slider, 114-movable locking block, 115-electromagnet, rear plate, 117-iron block, 118-bearing step, 12-four-way joint, 13-first hose, 131-second hose, 132-third hose, 133-fourth hose, 14-first push rod, 15-limit sleeve, 151-fixture block, 16-normal saline bottle, 161-bayonet, 17-operation button, 18-second push rod, 19-first cylinder, 20-second cylinder, 21-catch plate, 22-connecting tube, 23-first locking device, 231-second locking device, 232-third locking device, 233-fourth locking device, 24-threaded sleeve, and, 25-first solenoid valve, 26-second solenoid valve, 27-first air pump, 28-second air pump, 29-battery, 30-controller, 33-ventilation hole, 34-external power hole, 35-through hole.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Referring to the drawings, the invention provides a technical scheme that: an automated synthetic contrast agent and injection device, comprising: the device comprises a bottom plate 1, a bearing seat 3, a sliding rail 11, a first injector 7, a second injector 8, a four-way joint 12, a limit sleeve 15, a first cylinder 19 and a controller 30, wherein a first fixing seat 4 and a second fixing seat 5 are arranged at the top of the bottom plate 1, an arc groove 41, a mounting hole 42 and a limit groove 43 are arranged at the top of the first fixing seat 4, an arc groove 41, a mounting hole 42 and a limit groove 43 are also arranged at the top of the second fixing seat 5, the upper surface of the second fixing seat 5 and the bottom plate 1 are in inclined design, and the inclination angle between the upper surface of the second fixing seat and the bottom plate is 35-45 degrees; the cylinder body of the first syringe 7 is arranged in the circular arc groove 41 at the top of the first fixing seat 4, and the top of the cylinder body of the first syringe 7 is embedded into the limit groove 43, so that when the subsequent first piston rod 72 pushes the liquid in the cylinder body of the first syringe 7 forwards, the cylinder body of the first syringe 7 is still in a state of being fixed at the top of the first fixing seat 4, and the influence on the normal injection of the liquid in the cylinder body of the first syringe 7 is avoided; the cylinder body of the second syringe 8 is arranged in the circular arc groove 41 at the top of the second fixing seat 5, and the top of the cylinder body of the second syringe 8 is embedded into the limit groove 43, so that when the subsequent second piston rod 82 pushes the liquid in the cylinder body of the second syringe 8 forwards, the cylinder body of the second syringe 8 is still fixed at the top of the second fixing seat 5, and the influence on the normal injection of the liquid in the cylinder body of the second syringe 8 is avoided;
the bearing seat 3 is arranged on the right side of the first fixing seat 4, the bearing seat 3 is provided with a bearing cavity 31 and a through groove 32, the bearing cavity 31 is used for accommodating the loading limit sleeve 15, and the through groove 32 is used for accommodating the connecting pipe 22;
a fixed block 111 is arranged on one side of the sliding rail 11, the other end of the fixed block 111 is connected with a second spring 112, the other end of the second spring 112 is connected with a sliding block 113, a movable locking block 114 is arranged at the top of the sliding block 113, an electromagnet 115 is arranged in the movable locking block 114 and is tightly pressed by a rear plate 116, an iron block 117 is arranged on the other side of the sliding rail 11, the on-off electricity of the electromagnet 115 is controlled through a controller 30 so as to control the strong adsorption or release of the movable locking block 114 and the iron block 117, when the electromagnet 115 is electrified, the electromagnet 115 drives the movable locking block 114 to move towards the iron block 117, finally, the movable locking block 114 is clamped with the iron block 117, the clamping of a first hose 13 between the movable locking block 114 and the iron block 117 is interrupted, the middle part of the iron block 117 is provided with a bearing step 118, the bearing step 118 is used for bearing the first hose 13, when the electromagnet 115 is powered off, under the restoring force of the second spring 112, the second spring 112 pulls the sliding block 113 back, the locking block 114 is separated from the iron block 117, and the first hose 13 returns to the original state under the restoring force of the self;
the clamping block 151 is arranged in the limiting sleeve 15, the connecting pipe 22 is arranged at the bottom of the limiting sleeve 15, the needle is arranged at the top of the connecting pipe 22, the bearing cavity 31 in the limiting sleeve 15 is used for loading the physiological saline bottle 16, the bayonet 161 of the physiological saline bottle 16 is clamped through the clamping block 151, the needle at the top of the connecting pipe 22 is inserted into the physiological saline bottle 16, the physiological saline bottle 16 is made of plastic, the physiological saline bottle 16 can also be made of glass, but an air pressure pipe is additionally needed, so that when the physiological saline bottle 16 gradually decreases, the air pressure in the physiological saline bottle 16 still keeps consistent with the outside, and normal output of the physiological saline in the physiological saline bottle 16 is ensured;
the first push rod 14 of the first air cylinder 19 is connected with the clamping plate 21, and the first piston handle 71 matched with the first injector 7 is clamped in the clamping plate 21, so that the first push rod 14 of the first air cylinder 19 can conveniently push out forwards or shrink backwards, and the first piston rod 72 of the first injector 7 is synchronously driven to extend or shrink; similarly, the second push rod 18 of the second air cylinder 20 is also connected with the clamping plate 21, the second piston handle 81 matched with the second injector 8 is clamped in the clamping plate 21, so that the second push rod 18 of the second air cylinder 20 can conveniently push out forwards or shrink backwards, the second piston handle 81 of the second injector 8 is synchronously driven to stretch out or shrink, when the contrast agent microbubbles are required to be synthesized, the first push rod 14 of the first air cylinder 19 is controlled to stretch out, the second push rod 18 of the second air cylinder 20 is shrunk, namely the first piston rod 72 of the first injector 7 is stretched out, the second piston handle 81 of the second injector 8 is shrunk to form a push-push, and then the physiological saline and air are fully mixed to form the contrast agent microbubbles for subsequent contrast examination;
the four external connectors of the four-way joint 12 are respectively connected with a first hose 13, a second hose 131, a third hose 132 and a fourth hose 133, the other end of the first hose 13 is connected with the injection end of the first syringe 7, the second hose 131 is externally connected with a transfusion tube, the third hose 132 is connected with a connecting tube 22, the fourth hose 133 is connected with the injection end of the second syringe 8, the first hose 13, the second hose 131, the third hose 132 and the fourth hose 133 are respectively provided with a first locking device 23, a second locking device 231, a third locking device 232 and a fourth locking device 233, the first locking device 23 consists of a movable locking block 114 and an iron block 117, the electromagnet 115 arranged in the movable locking block 114 is electrified to be strongly adsorbed with the iron block 117, thereby clamping the first hose 13 and blocking the liquid circulation, the principles of the second locking device 231, the third locking device 232 and the fourth locking device 233 are consistent with the first locking device 23, the second hose 131, the third hose 132 and the fourth hose 133 can be controlled to be clamped respectively, a blocking detection device 6 is arranged at the outer side of the second locking device 231 to detect that the second hose 131 is blocked, a pressing plate 62 is arranged at the top of the blocking detection device 6, the pressing plate 62 is connected with the blocking detection device 6 through a hinge, a fastener 63 is arranged at the other side of the pressing plate 62 and used for clamping a clamping groove 61 at one side of the blocking detection device 6, a signal output end of the blocking detection device 6 is connected with a signal input end of the controller 30, the blocking detection device 6 also comprises a guide rod 64, a guide spring 65, a movable cavity 66, a pressure sensor 67 and a circuit board 68, the guide rod 64 can move up and down in the movable cavity 66 and supports the guide rod 64 upwards through the guide spring 65, the top of the guide rod 64 is contacted with the second hose 131, the pressure sensor 67 is arranged below the guide rod 64, the pressure sensor 67 is welded on the circuit board 68, the circuit board 68 is electrically connected with the controller 30, the bottom of the guide rod 64 is separated from the top of the pressure sensor 67 by 0.1-0.2mm, in the injection process, the second hose 131 passes through the top of the blockage detection device 6, the pressing plate 62 is fixed on the top of the blockage detection device 6 through the fastener 63, the second hose 131 is in a slightly compressed state, namely, the bottom of the pressing plate 62 presses down the second hose 131, the second hose 131 presses down the guide rod 64, at the moment, the distance between the bottom of the guide rod 64 and the top of the pressure sensor 67 is still 0.05-0.1mm, when the infusion tube is blocked due to bending or needle displacement in a patient's hand, the hydraulic pressure in the second hose 131 is increased, the second hose 131 is restored to extrude the guide rod 64, the guide rod 64 is deflected downwards to touch the pressure sensor 67, the pressure sensor 67 feeds back signals to the controller 30, the controller 30 controls the air outlet end of the second solenoid valve 26 to be closed, the second push rod 18 of the second air cylinder 20 stops pushing, the second locking device 231 is controlled by the controller 231 to lock the second hose 131, and then the mixed contrast agent is blocked, and the contrast agent is automatically locked by the second push rod 131, and the contrast agent is automatically foamed when the contrast agent is injected into the contrast tube and the contrast tube is blocked by the contrast tube, and the contrast agent is automatically injected by the contrast tube, the contrast tube is automatically foamed, and the contrast tube is automatically blocked by the contrast device and the contrast tube is automatically injected when the contrast device is not blocked;
the signal output ends of the controller 30 are respectively connected with the signal input ends of the first electromagnetic valve 25, the second electromagnetic valve 26, the first locking device 23, the second locking device 231, the third locking device 232 and the fourth locking device 233, namely the signal output ends of the controller 30 are connected with the power supply access ends of the electromagnets 115 in the first locking device 23, the second locking device 231, the third locking device 232 and the fourth locking device 233, the power on and off of the electromagnets 115 are controlled through the controller 30, and finally the clamping or the releasing of the first locking device 23, the second locking device 231, the third locking device 232 and the fourth locking device 233, namely the clamping or the releasing of the movable locking block 114 and the iron block 117 are controlled, and finally the closing or the opening of the first hose 13, the second hose 131, the third hose 132 and the fourth hose 133 are controlled.
The movable locking piece 114 is in an arc convex shape on one side close to the first hose 13, the iron piece 117 is in an arc concave shape on one side close to the first hose 13, and the movable locking piece 114 is matched with one convex-concave of the iron piece 117 to clamp, so that the clamping closing effect of the first hose 13 is better.
The first movable clamping piece 9 and the second movable clamping piece 10 are respectively installed in the installation holes 42 at the tops of the first fixing seat 4 and the second fixing seat 5, the first movable clamping piece 9 and the second movable clamping piece 10 are fixed on the first fixing seat 4 and the second fixing seat 5 through the equal-height screws 91, a first spring 92 is arranged between the boss of the equal-height screws 91 and the interiors of the first movable clamping piece 9 and the second movable clamping piece 10, so that the first movable clamping piece 9 and the second movable clamping piece 10 can be elastically stretched up and down and rotate along the axis of the equal-height screws 91, the tops of the first movable clamping piece 9 and the second movable clamping piece 10 are in an arc shape, the diameter of the arc is equal to the diameter of the first injector 7 and the diameter of the second injector 8, when the first injector 7 and the second injector 8 are required to be replaced, the first movable clamping piece 9 and the second movable clamping piece 10 are lifted up and rotated by 90 degrees, and then the first movable clamping piece 9 and the second movable clamping piece 10 are rotated by 90 degrees after replacement, and the first movable clamping piece 9 and the second movable clamping piece 10 are loosened again, and the first movable clamping piece 9 and the second injector are compressed by the second injector 8 are pressed again.
The air source input end of the first air cylinder 19 is connected with the air outlet end of the first electromagnetic valve 25 through an air pipe, the air inlet end of the first electromagnetic valve 25 is connected with the air outlet end of the first air pump 27 through an air pipe, the air source input end of the second air cylinder 20 is connected with the air outlet end of the second electromagnetic valve 26 through an air pipe, the air inlet end of the second electromagnetic valve 26 is connected with the air outlet end of the second air pump 28 through an air pipe, the motors of the first air pump 27 and the second air pump 28 are controlled to work through pressure switches arranged on the first air pump 27 and the second air pump 28, so that the air pressure in a tank body of the first air pump 27 and the second air pump 28 is kept in a stable state, and then the controller 30 is used for controlling the starting or closing of the first air pump 27 and the second air pump 28.
The first electromagnetic valve 25 and the second electromagnetic valve 26 are preferably five-position three-way electromagnetic valves, so that the gas reversing through the five-position three-way electromagnetic valves is facilitated, the extension or contraction of the first push rod 14 of the first air cylinder 19 or the second push rod 18 of the second air cylinder 20 is further controlled, and finally the outward transfusion or inward liquid suction of the first injector 7 or the second injector 8 is controlled.
The power input end of the controller 30 is electrically connected with the power output end of the storage battery 29, the signal input end of the controller 30 is in signal connection with the operation button 17 at the top of the shell 2, the reversing of the gas output ends of the first electromagnetic valve 25 and the second electromagnetic valve 26 can be controlled through the operation button 17, so that the outward transfusion or inward liquid suction of the first injector 7 or the second injector 8 can be controlled, and the locking or unlocking of the first locking device 23, the second locking device 231, the third locking device 232 and the fourth locking device 233 can be controlled through the operation button 17.
The shell 2 is fixed at the top of the bottom plate 1 through bolt installation, the rear side of the shell 2 is provided with a vent hole 33 and an external power hole 34, the front side of the shell 2 is provided with a through hole 35, the normal ventilation of the first air pump 27 and the second air pump 28 is kept through the vent hole 33, and the external power of the first air pump 27 and the second air pump 28 or the charging of the storage battery 29 can be realized through the external power hole 34.
The controller 30 can control the locking or unlocking of the first locking device 23, the second locking device 231, the third locking device 232 and the fourth locking device 233, so as to form three paths of the first hose 13, the second hose 131, the third hose 132 and the fourth hose 133, wherein the first path is as follows: the first locking device 23 and the second locking device 231 are locked, the third locking device 232 and the fourth locking device 233 are opened, and a passage is formed between the physiological saline bottle 16 and the second syringe 8, and the passage is used for the second syringe 8 to extract the physiological saline in the physiological saline bottle 16; the second path: the second locking device 231 and the third locking device 232 are locked, the first locking device 23 and the fourth locking device 233 are opened, and a passage is formed between the first syringe 7 and the second syringe 8, and the passage mixes the air in the first syringe 7 with the normal saline in the second syringe 8 to form contrast agent microbubbles; third path: the first locking device 23 and the third locking device 232 are locked, the second locking device 231 and the fourth locking device 233 are opened, and a passage is formed between the second syringe 8 and the second hose 131, that is, a passage is formed between the second syringe 8 and an infusion tube externally connected with the second hose 131, and the passage is formed by injecting the mixed contrast agent microbubbles into a patient through the infusion tube for subsequent right heart radiography examination.
A pre-charging stage: the physiological saline bottle 16 loaded with 100 milliliters of physiological saline is placed in the limit sleeve 15, the bayonet 161 of the physiological saline bottle 16 is clamped and limited through the clamping block 151, at the moment, the needle at the top of the connecting pipe 22 which is integrally designed with the limit sleeve 15 is inserted into the physiological saline bottle 16, the other end at the bottom of the connecting pipe 22 is connected with the third hose 132 through the threaded sleeve 24, the first hose 13 is in threaded connection with the injection end of the first injector 7, the second hose 131 is externally connected with the infusion tube, the fourth hose 133 is in threaded connection with the injection end of the second injector 8, the physiological saline is used for prefilling the first hose 13, the second hose 131, the third hose 132 and the fourth hose 133 firstly, the prefilling button is pressed on the operating button 17, the controller 30 firstly controls the first locking device 23 and the second locking device 231 to be locked, the third locking device 232 and the fourth locking device 233 to be opened afterwards, then the second electromagnetic valve 26 and the second air pump 28 are controlled to be started, the second push rod 18 is retracted backwards, the second piston rod 82 is synchronously pulled backwards, the second injector 8 extracts 5ml of physiological saline in the physiological saline bottle 16, the first injector 7 is preloaded with 1ml of air in advance, the first injector 7 and the second injector 8 are 10ml of injectors with threaded injection ends, when the second injector 8 extracts physiological saline, the controller 30 firstly controls the first locking device 23 and the third locking device 232 to lock, the second locking device 231 and the fourth locking device 233 are opened, the air delivery end of the second electromagnetic valve 26 is controlled to reverse, the second push rod 18 of the second air cylinder 20 is pushed forwards, finally the physiological saline in the second injector 8 is prefilled with the second hose 131, the third hose 132 and the fourth hose 133 and is output through the second hose 131, at this time, the second hose 131 is not connected to the infusion tube.
Mixing contrast agent microbubbles phase: the first syringe 7 is preloaded with 1ml of air, the mixed contrast agent microbubble button is pressed down on the operation button 17, the controller 30 firstly controls the first locking device 23 and the second locking device 231 to be locked, the third locking device 232 and the fourth locking device 233 are opened, the second push rod 18 is retracted backwards, the second piston rod 82 is synchronously pulled backwards, at the moment, the second syringe 8 extracts 9ml of physiological saline in the physiological saline bottle 16, after the second syringe 8 extracts physiological saline, the air outlet end of the second electromagnetic valve 26 stops delivering air, the controller 30 continuously controls the second locking device 231 and the third locking device 232 to be locked, the first locking device 23 and the fourth locking device 233 are opened, the first air pump 27 and the second air pump 28 are started, the first push rod 14 of the first air cylinder 19 pushes the first piston rod 72 of the first syringe 7 to push inwards, the second push rod 18 of the second air cylinder 20 drives the second piston rod 82 of the second syringe 8 to pull outwards, the air in the first syringe 7 is mixed with the physiological saline in the second syringe 8, namely, firstly, the first push rod 14 of the first cylinder 19 pushes the first piston rod 72 of the first syringe 7 to move inwards for 1ml of stroke and then stop, meanwhile, the second push rod 18 of the second cylinder 20 pulls the second piston rod 82 of the second syringe 8 to pull outwards for 1ml of stroke and then stop, then the controller 30 controls the air outlet ends of the first electromagnetic valve 25 and the second electromagnetic valve 26 to reverse, the second push rod 18 of the second cylinder 20 pushes the second piston rod 82 of the second syringe 8 to move inwards for 10ml of stroke and then stop, meanwhile, the first push rod 14 of the first cylinder 19 drives the first piston rod 72 of the first syringe 7 to move outwards for 10ml of stroke and then the first push rod 14 of the first cylinder 19 pushes the first piston rod 72 of the first syringe 7 to move inwards for 10ml of stroke and then stop, simultaneously, the second push rod 18 of the second air cylinder 20 pulls the second piston rod 82 of the second injector 8 to pull outwards for 10ml of strokes, so that the formation of the first mixed contrast agent microbubbles is completed, the controller 30 continuously controls the air outlet ends of the first electromagnetic valve 25 and the second electromagnetic valve 26 to change directions respectively, so that the first push rod 14 of the first air cylinder 19 is controlled to push the first piston rod 72 of the first injector 7 to push inwards, the second push rod 18 of the second air cylinder 20 pulls the second piston rod 82 of the second injector 8 to move outwards, and then the second mixed contrast agent microbubbles are secondarily mixed, so that the first injector 7 and the second injector 8 synchronously suck back and forth for 20 times (10 ml in each sucking stroke), and finally the contrast agent microbubbles with higher mixing degree are formed, and finally the contrast agent microbubbles are totally transferred into the second injector 8 for 10ml.
Contrast agent microbubble injection phase: the port of the second hose 131 is also connected with one end of the infusion tube through the matched threaded sleeve 24, the needle at the other end of the infusion tube is inserted into an intravenous injection position, then an injection button in the operation button 17 is pressed down, after that, the controller 30 firstly controls the first locking device 23 and the third locking device 232 to be locked, the second locking device 231 and the fourth locking device 233 to be opened (namely the third passage), then controls the second air pump 28 and the second electromagnetic valve 26 to be started, the second push rod 18 of the second air cylinder 20 is pushed forward, the second piston rod 82 is synchronously pushed forward, the injection process is controlled by the controller 30 to control the second air pump 28 to slowly feed air to the second air cylinder 20, and then the second push rod 18 of the second air cylinder 20 is controlled to be pushed forward slowly and pushed forward, and finally the contrast agent microbubbles in the second injector 8 are slowly injected into a patient for 9ml, and the subsequent cardiography examination is facilitated.
Since each patient needs 4-6 times for carrying out cardiac radiography examination, each time 9ml can successfully complete radiography examination, and the device uses an injector with the specification of 10ml, the second fixing seat 5 of the device adopts a slope design, namely, the second injector 8 is in an inclined state during injection, after 9ml of contrast agent microbubbles are injected, 1ml of the contrast agent microbubbles stay in the second injector 8, due to low air density, undissolved air stays at the high position of the second injector 8, finally 1ml of the contrast agent microbubbles are mainly air, the part of air can be recycled, the contrast agent microbubbles are formed again after being mixed with physiological saline extracted next time, afterwards, a repeated mixing contrast agent microbubbles button in the operation button 17 can be pressed down, the controller 30 firstly controls the first locking device 23 and the second locking device 231 to be locked, the third locking device 232 and the fourth locking device 233 are opened, the second push rod 18 is retracted backwards, the second piston rod 82 is synchronously pulled backwards, at this time, the second syringe 8 draws 9ml of physiological saline in the physiological saline bottle 16, after the second syringe 8 draws physiological saline, the air outlet end of the second electromagnetic valve 26 stops delivering air, the controller 30 continuously controls the second locking device 231 and the third locking device 232 to lock, the first locking device 23 and the fourth locking device 233 are opened, the first air pump 27 and the second air pump 28 are started, the first push rod 14 of the first air cylinder 19 drives the first piston rod 72 of the first syringe 7 to pull outwards, the second push rod 18 of the second air cylinder 20 pushes the second piston rod 82 of the second syringe 8 to push inwards, the physiological saline and air of the second syringe 8 are moved into the first syringe 7, the first syringe 7 and the second syringe 8 are synchronously pumped back and forth 20 times, the final contrast agent microbubbles are transferred into the second syringe 8 for the next contrast agent microbubble injection.
Therefore, when the contrast agent microbubbles are injected into the patient, the second hose 131, the third hose 132 and the fourth hose 133 are pre-filled with the normal saline, then the normal saline in the normal saline bottle 16 is extracted by the second injector 8 and mixed with the air in the first injector 7 to form the contrast agent microbubbles, and finally the contrast agent microbubbles are injected into the intravenous injection end of the patient through the second hose 131 and the externally connected infusion tube, and meanwhile, the blockage detection device 6 detects that the infusion tube is blocked due to bending or needle displacement in the patient hand in the injection process of the contrast agent microbubbles, and the injection is controlled to stop, so that the safety of the automatic synthetic contrast agent and the injection device is improved.
In summary, this automatic synthetic contrast agent and injection device, through setting up the first air pump, the second air pump, first electromagnetic valve, structural connection between second electromagnetic valve and first cylinder, the second cylinder, by traditional manual operation radiography syringe change automatic radiography injection device, original operation oscillation frequency is not up to standard, mix the number of times inadequately, medical personnel work load is big scheduling technical problem, through realizing automation, standardization of this inspection, it is accurate to grasp in the mixed frequency of contrast agent, the number of times, also can let the contrast agent microbubble size in the syringe even simultaneously, the frequency is not up to standard when having compensatied artificial operation, the number of times inadequately influences, thereby improve the accuracy of radiography inspection, repeatability, reduce the difference of inspection result because of different operators leads to, realize improving inspection efficiency, reduce manpower resource cost, promote the popularization and application of inspection item in clinic.
It is noted that relational terms such as first and second, and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Moreover, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising one … …" does not exclude the presence of other like elements in a process, method, article, or apparatus that comprises the element.
Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (10)
1. An automated synthetic contrast agent and injection device, comprising:
the novel anti-theft device comprises a bottom plate (1), wherein a first fixing seat (4) and a second fixing seat (5) are arranged at the top of the bottom plate (1), an arc groove (41), a mounting hole (42) and a limiting groove (43) are formed in the top of the first fixing seat (4), an arc groove (41), a mounting hole (42) and a limiting groove (43) are also formed in the top of the second fixing seat (5), and the upper surface of the second fixing seat (5) and the bottom plate (1) are obliquely designed;
the bearing seat (3), the bearing seat (3) is arranged on the right side of the first fixing seat (4), and the bearing seat (3) is provided with a bearing cavity (31) and a through groove (32);
the sliding rail (11), one side of the sliding rail (11) is provided with a fixed block (111), the other end of the fixed block (111) is connected with a second spring (112), the other end of the second spring (112) is connected with a sliding block (113), the top of the sliding block (113) is provided with a movable locking block (114), the inside of the movable locking block (114) is provided with an electromagnet (115) and is compressed through a rear plate (116), the other side of the sliding rail (11) is provided with an iron block (117), and the middle part of the iron block (117) is provided with a bearing step (118);
the first injector (7), the first injector (7) cylinder is installed in the arc groove (41) at the top of the first fixing seat (4), and the top of the first injector (7) cylinder is embedded into the limit groove (43);
the second injector (8), the cylinder body of the second injector (8) is installed in the arc groove (41) at the top of the second fixing seat (5), and the top of the cylinder body of the second injector (8) is embedded into the limit groove (43);
the device comprises a limiting sleeve (15), wherein a clamping block (151) is arranged in the limiting sleeve (15), a connecting pipe (22) is arranged at the bottom of the limiting sleeve (15), a needle is arranged at the top of the connecting pipe (22), a bearing cavity (31) in the limiting sleeve (15) is used for loading a physiological saline bottle (16), a bayonet (161) of the physiological saline bottle (16) is clamped through the clamping block (151), and the needle at the top of the connecting pipe (22) is inserted into the physiological saline bottle (16);
the first push rod (14) of the first air cylinder (19) is connected with the clamping plate (21), and the first piston handle (71) matched with the first injector (7) is clamped in the clamping plate (21);
the four-way joint (12), four external interfaces of the four-way joint (12) are respectively connected with a first hose (13), a second hose (131), a third hose (132) and a fourth hose (133), the other end of the first hose (13) is connected with the injection end of the first syringe (7), the second hose (131) is externally connected with a transfusion tube, the third hose (132) is connected with the injection end of the second syringe (8), the fourth hose (133) is connected with the injection end of the second syringe (8), and the first hose (13), the second hose (131), the third hose (132) and the fourth hose (133) are respectively provided with a first locking device (23), a second locking device (231), a third locking device (232) and a fourth locking device (233), and a blockage detection device (6) is arranged outside the second locking device (231) for detecting that the output liquid of the second hose (131) is blocked;
the signal output end of the controller (30) is respectively connected with the signal input ends of the first electromagnetic valve (25), the second electromagnetic valve (26), the first locking device (23), the second locking device (231), the third locking device (232) and the fourth locking device (233).
2. An automated synthetic contrast agent and injection apparatus according to claim 1, wherein: the first locking device (23) consists of a movable locking block (114) and an iron block (117), an electromagnet (115) arranged in the movable locking block (114) is electrified to be strongly adsorbed with the iron block (117), so that the first hose (13) is clamped, liquid circulation is blocked, the principles of the second locking device (231), the third locking device (232) and the fourth locking device (233) are consistent with those of the first locking device (23), and the second hose (131), the third hose (132) and the fourth hose (133) can be controlled to be clamped respectively.
3. An automated synthetic contrast agent and injection apparatus according to claim 1, wherein: the side of the movable locking block (114) close to the first hose (13) is in an arc convex shape, and the side of the iron block (117) close to the first hose (13) is in an arc concave shape.
4. An automated synthetic contrast agent and injection apparatus according to claim 1, wherein: the utility model discloses a syringe, including first fixing base (4), second fixing base (5), first movable fastener (9), second movable fastener (10) are installed respectively in mounting hole (42) at first fixing base (4) and second fixing base (5) top, first movable fastener (9), second movable fastener (10) are fixed in on first fixing base (4) and second fixing base (5) through contour screw (91), boss and first movable fastener (9), second movable fastener (10) inside between be equipped with a first spring (92) to make first movable fastener (9), second movable fastener (10) elasticity from top to bottom and follow the rotation of contour screw (91), first movable fastener (9), second movable fastener (10) top are circular-arc, and circular-arc diameter equals with first syringe (7) and second syringe (8) diameter.
5. An automated synthetic contrast agent and injection apparatus according to claim 1, wherein: the air source input end of the first air cylinder (19) is connected with the air outlet end of the first electromagnetic valve (25) through an air pipe, the air inlet end of the first electromagnetic valve (25) is connected with the air outlet end of the first air pump (27) through an air pipe, the air source input end of the second air cylinder (20) is connected with the air outlet end of the second electromagnetic valve (26) through an air pipe, and the air inlet end of the second electromagnetic valve (26) is connected with the air outlet end of the second air pump (28) through an air pipe.
6. An automated synthetic contrast agent and injection apparatus according to claim 1, wherein: the first electromagnetic valve (25) and the second electromagnetic valve (26) are five-position three-way electromagnetic valves.
7. An automated synthetic contrast agent and injection apparatus according to claim 1, wherein: the power input end of the controller (30) is electrically connected with the power output end of the storage battery (29), and the signal input end of the controller (30) is in signal connection with the operation button (17) at the top of the shell (2).
8. An automated synthetic contrast agent and injection apparatus according to claim 1, wherein: the shell (2) is fixed at the top of the bottom plate (1) through bolt installation, the rear side of the shell (2) is provided with a vent hole (33) and an external power hole (34), and the front side of the shell (2) is provided with a through hole (35).
9. An automated synthetic contrast agent and injection apparatus according to claim 1, wherein: the top of the blockage detection device (6) is provided with a pressing plate (62), the pressing plate (62) is connected with the blockage detection device (6) through a hinge, the other side of the pressing plate (62) is provided with a fastener (63) for clamping with a clamping groove (61) on one side of the blockage detection device (6), and a signal output end of the blockage detection device (6) is connected with a signal input end of the controller (30).
10. An automated synthetic contrast agent and injection apparatus according to claim 1, wherein: the upper surface of the second fixing seat (5) and the bottom plate (1) are inclined at an angle of 35-45 degrees.
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| CN110215563A (en) * | 2019-05-08 | 2019-09-10 | 浙江一缘医疗器械有限公司 | A kind of full-automatic hybrid injection pump and system and application method |
| CN109984772A (en) * | 2019-05-20 | 2019-07-09 | 广东省人民医院(广东省医学科学院) | A kind of left cardiography check device |
| JP7144465B2 (en) * | 2020-01-20 | 2022-09-29 | ディーブイエックス株式会社 | Contrast injection device and injection line kit |
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| CN117398546B (en) * | 2023-12-14 | 2024-02-27 | 无忧跳动医疗科技(深圳)有限公司 | Device and method for automatically performing foaming tests |
| WO2025124569A1 (en) * | 2023-12-14 | 2025-06-19 | 无忧跳动医疗科技(深圳)有限公司 | Apparatus, system and method for automated execution of bubble test |
| CN118787805B (en) * | 2024-09-12 | 2024-11-22 | 珠海德瑞医疗器械有限公司 | CT contrast injection device |
| CN119280563B (en) * | 2024-12-12 | 2025-03-21 | 上海形状记忆合金材料有限公司 | A microbubble generator |
| CN119770787B (en) * | 2025-01-13 | 2025-06-10 | 中国人民解放军总医院第四医学中心 | Contrast agent injection device and use method |
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