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CN107233115A - Occluder for left auricle - Google Patents

Occluder for left auricle Download PDF

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Publication number
CN107233115A
CN107233115A CN201610184108.XA CN201610184108A CN107233115A CN 107233115 A CN107233115 A CN 107233115A CN 201610184108 A CN201610184108 A CN 201610184108A CN 107233115 A CN107233115 A CN 107233115A
Authority
CN
China
Prior art keywords
left auricle
occluder
component
heart
flexible connector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201610184108.XA
Other languages
Chinese (zh)
Other versions
CN107233115B (en
Inventor
汪振
周毅
姚遥
李俊菲
罗七
罗七一
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shanghai Zuoxin Medical Technology Co., Ltd
Original Assignee
Shanghai Microport Medical Group Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Microport Medical Group Co Ltd filed Critical Shanghai Microport Medical Group Co Ltd
Priority to CN201610184108.XA priority Critical patent/CN107233115B/en
Publication of CN107233115A publication Critical patent/CN107233115A/en
Application granted granted Critical
Publication of CN107233115B publication Critical patent/CN107233115B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/12Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/12Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12027Type of occlusion
    • A61B17/12031Type of occlusion complete occlusion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/12Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12122Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder within the heart
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/12Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12159Solid plugs; being solid before insertion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/12Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B2017/1205Introduction devices
    • A61B2017/12054Details concerning the detachment of the occluding device from the introduction device

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Prostheses (AREA)
  • Surgical Instruments (AREA)

Abstract

The invention provides a kind of occluder for left auricle, the occluder for left auricle includes plugging structure and fixed structure, and the occluder for left auricle also includes:Detachable adjustment structure, the detachable adjustment structure includes first component and the second component that can be separated or close with the first component, the first component and the second component can do relative motion, the first component is connected with the plugging structure, and the second component is connected with the fixed structure.The regulation of depth/length for occluder for left auricle can be realized by the relative motion in detachable adjustment structure between first component and second component, so as to adapt to the left auricle of heart of varying depth;Further, it can be split between the detachable adjustment structure and fixed structure, so that in face of the left auricle of heart of shape, different sizes, the detachable adjustment structure can select to connect various sizes of fixed structure, to adapt to different left auricle of heart.

Description

Occluder for left auricle
Technical field
The present invention relates to technical field of medical instruments, more particularly to a kind of occluder for left auricle.
Background technology
Auricular fibrillation (atrial fibrillation) is that atrial fibrillation is sent out in clinically most common perpetual arrhythmia, general population Sick rate is 0.5%~1.3%.The topmost harm of atrial fibrillation is easily caused after promoting thrombosis, thrombus breaks loose The complication such as cerebral apoplexy, peripheral vascular embolism, dramatically increase disability rate and fatal rate.Cerebral apoplexy be atrial fibrillation most There are about 15,000,000 people suffers from cerebral apoplexy every year in the common, complication that harm is maximum, world wide, wherein 20%~25% is attributed to atrial fibrillation.The cardiogenic thrombus of rheumatic heart disease patients with atrial fibrillation of studies have shown that 60% comes From more than 90% thrombosis in left auricle of heart, Non-valvular disease patients with atrial fibrillation in left auricle of heart.Therefore, the left heart is intervened Ear prevents patients with atrial fibrillation thromboembolism, especially palsy, with important theoretical foundation and clinical meaning.
Anticoagulant therapy is currently the standard method for preventing atrial fibrillation palsy complication, but anticoagulant therapy is present necessarily Limitation.Therefore it is significant using more efficient safe measure prevention atrial fibrillation palsy.It is at present to use more Utilize the method for the inaccessible left auricle of heart of interventional therapy.Conventional occluder for left auricle has with WATCHMAN For plunger type plugging device in the monomer of representative and with plug that AMPLATZER Cardiac Plug (ACP) are representative Disc type occluder for left auricle.
1st, the defect and deficiency of interior plunger type occluder for left auricle
Interior plunger type plugging device is the framework using Nitinol as self-expanding structure, around there is fixed barb, the heart Room face is covered by polytetrafluoroethylstephanoporate stephanoporate permeable membrane, and blood flow can pass in and out left auricle of heart.
When the apparatus fills in left auricle of heart, due to left auricle of heart oral area shape very irregular, and the deformation of the apparatus It is limited in one's ability, it is impossible to block left auricle of heart oral area completely, it is difficult to which that elimination causes left auricle of heart portion to be formed due to atrial fibrillation Thrombus.The planform of left auricle of heart is different, varying depth, also multi-cavity structure, interior plunger type left atrial appendage occlusion Device can not adapt to the anatomical structure of all left auricle of hearts completely, while stable fixation can not be realized.
2nd, the defect and deficiency of dish-type occluder for left auricle are filled in
Fill in dish-type plugging device be a kind of pair of dish sample left atrial appendage occlusion device, by be placed in left auricle of heart butterfly blade and Butterfly cap is constituted, and is connected in the middle of the two by the waist being recessed, butterfly blade, which is placed in left auricle of heart, prevents plugging device from moving Position, butterfly cap seals left auricle of heart oral area.
It is closure disk and fixed disk one to fill in disc type occluder for left auricle, it is impossible to completely independent deforms, works as plug Son is filled in after left auricle of heart, when disc part is buckled in the oral area of left auricle of heart, can be pulled, make by plug portion The oral area of left auricle of heart can not be fully fitted in by obtaining disc part, be extremely difficult to optimal plugging effect.Due to plug The subdivision and length adjustment of disc part is limited is difficult to optimal fixation and bloodstream blocking, while disc knot Structure is simultaneously not suitable with different left auricle of heart cavity shapes.
In a word, either interior plunger type or plug dish-type occluder for left auricle, for different, varying depth Left auricle of heart, have certain defect and deficiency, it is therefore necessary in the further investigation of plugging device configuration aspects to solve Defect present in prior art and weak point.
The content of the invention
It is an object of the invention to provide a kind of occluder for left auricle, to solve existing occluder for left auricle pair The problem of the adaptability of different, varying depth left auricle of heart is not strong.
In order to solve the above technical problems, the present invention provides a kind of occluder for left auricle, the occluder for left auricle Including plugging structure and fixed structure, the occluder for left auricle also includes:Detachable adjustment structure, institute Stating detachable adjustment structure includes first component and can separate or close with the first component second Part, the first component and the second component can do relative motion, the first component and the envelope Bridging structure is connected, and the second component is connected with the fixed structure.
Optionally, in described occluder for left auricle, the detachable adjustment structure is screw nut knot Structure, external splines internal spline structure or buckle structure.
Optionally, in described occluder for left auricle, the occluder for left auricle also includes at least one elasticity Connector, the first component is connected by the Flexible Connector with the plugging structure.
Optionally, in described occluder for left auricle, the occluder for left auricle also includes connection fixture, One end of the connection fixture is connected with one end of the Flexible Connector, the connection fixture it is another End is connected with the detachable adjustment structure.
Optionally, in described occluder for left auricle, the two ends of the Flexible Connector are tied to be fixedly mounted Structure, centre is helical spring structure.
Optionally, in described occluder for left auricle, the occluder for left auricle also includes a joint, institute Stating joint is used to be connected with an occluder for left auricle conveying device.
Optionally, in described occluder for left auricle, the fixed structure includes some hooks.
Optionally, in described occluder for left auricle, the fixed structure is on a disc, the disc With some hooks.
In the occluder for left auricle that provides of the present invention, pass through first component in detachable adjustment structure and the Relative motion between two parts can realize the regulation of depth/length for occluder for left auricle, so that suitable Answer the left auricle of heart of varying depth;Further, can be between the detachable adjustment structure and fixed structure Split, so that in face of the left auricle of heart of shape, different sizes, the detachable adjustment structure can the company of selection Various sizes of fixed structure is connect, to adapt to different left auricle of heart.
Brief description of the drawings
Fig. 1 is the structural representation of the occluder for left auricle of the embodiment of the present invention one;
Fig. 2 is the detachable adjustment structure of the embodiment of the present invention and the structural representation of connection fixture;
Fig. 3 is the structural representation of the Flexible Connector of the embodiment of the present invention;
Fig. 4 is the structural representation of another occluder for left auricle of the embodiment of the present invention one;
Fig. 5 is the use schematic diagram of multiple Flexible Connectors of the embodiment of the present invention two;
Fig. 6 is the structural representation of the detachable adjustment structure of the embodiment of the present invention three;
Fig. 7 is the structural representation of the detachable adjustment structure of the embodiment of the present invention four.
Embodiment
Occluder for left auricle proposed by the present invention is made further specifically below in conjunction with the drawings and specific embodiments It is bright.According to following explanation and claims, advantages and features of the invention will become apparent from.It should be noted It is that accompanying drawing is using very simplified form and uses non-accurately ratio, only to conveniently, lucidly Aid in illustrating the purpose of the embodiment of the present invention.Particularly, it is past by each accompanying drawing content to be protruded is different It is past to employ different ratios.
【Embodiment one】
Fig. 1 is refer to, it is the structural representation of the occluder for left auricle of the embodiment of the present invention one.Such as Fig. 1 institutes Show, the occluder for left auricle 1 includes:To the plugging structure 10 blocked to left auricle of heart, to incite somebody to action The fixed structure 11 that the occluder for left auricle 1 is fixed on the left auricle of heart, and detachable regulation knot Structure 12, the detachable adjustment structure 12 includes first component 120 and can be with the first component 120 The second component 121 for separating or closing, the first component 120 and the second component 121 can do phase To motion, the first component 120 is connected with the plugging structure 10, the second component 121 with it is described Fixed structure 11 is connected.In addition, the occluder for left auricle 1 also includes a joint 13, the joint 13 For being connected with an occluder for left auricle conveying device (not shown in figure 1).
Pass through the relative motion in detachable adjustment structure 12 between first component 120 and second component 121 The regulation of depth/length for occluder for left auricle 1 can be realized, so as to adapt to the left auricle of heart of varying depth; Further, (i.e. described can be split between the detachable adjustment structure 12 and fixed structure 11 Can be separated between two parts 121 and the fixed structure 11) so that in face of a left side for shape, different sizes Auricle, the detachable adjustment structure 12 can select to connect various sizes of fixed structure 11, to adapt to Different left auricle of heart.
Specifically, when the first component 120 is separated with the second component 121, the fixed structure 11 can separate with the second component 121;When the first component 120 is closed with the second component 121 When rising, the fixed structure 11 can be connected with the second component 121.
In the embodiment of the present application, the detachable adjustment structure 12 is screw nut structure, here, institute First component 120 is stated for helicitic texture, the second component 121 is nut structure, the second component 121 Can be in rotary moving on the first component 120, i.e., described first component 120 and the second component 121 It can do relative motion.
Please continue to refer to Fig. 1, in the embodiment of the present application, the first component 120 passes through the fixed structure Through hole on 11, the second component 121 is screwed on the first component 120, thus with the fixation Structure 11 connects and fixes the fixed structure 11.Here, by screwing the second component 121 Depth/length of the occluder for left auricle 1 is can adjust, so that the occluder for left auricle 1 is adapted to not Same left auricle of heart depth.Meanwhile, the detachable adjustment structure 12 can connect various sizes of fixed knot Structure 11, so as to adapt to different left auricle of heart.
Further, the occluder for left auricle 1 also includes an at least Flexible Connector 14, described first Part 120 is connected by the Flexible Connector 14 with the plugging structure 10.It is preferred that, the elasticity is even The depth of fitting 14 is adjustable.Fig. 3 is refer to, it is the structural representation of the Flexible Connector of the embodiment of the present invention Figure.As shown in figure 3, the Flexible Connector 14 is an elastomeric element, it can be by metal or plastics system Into.Specifically, is structure is fixedly mounted in the two ends of the Flexible Connector 14, centre is helical spring structure. For example, the two ends of the Flexible Connector 14 are screw nut structure, pass through the screw nut structure, institute State Flexible Connector 14 just can be fixedly connected with the structure such as plugging structure 10 or first component 120.
Fig. 1 is please also refer to, here, the Flexible Connector 14 and connecing in the plugging structure 10 First 13 connection, by being pressed for the joint 13, thus it is possible to vary the depth of the Flexible Connector 14/ Length, so that the occluder for left auricle 1 can preferably adapt to the left auricle of heart of varying depth.Enter one Step, pad can be set between the Flexible Connector 14 and the joint 13, so as to ensure the bullet The intensity and reliability connected between property connector 14 and the joint 13.
Further, the occluder for left auricle 1 also includes connection fixture 15, the connection fixture 15 One end be connected with one end of the Flexible Connector 14, the other end of the connection fixture 15 with it is described Detachable adjustment structure 12 is connected.
Fig. 2 is refer to, it is that the detachable adjustment structure of the embodiment of the present invention and the structure of connection fixture are shown It is intended to.In the embodiment of the present application, the connection fixture 15 is through-hole structure, wherein, the through hole knot The both ends of structure are provided with screw nut structure.The Flexible Connector 14 and the first component 120 lead to The screw nut structure is crossed to be fixedly connected with the connection fixture 15.Specifically, the connection fixture 15 one end 150 is connected with the Flexible Connector 14, the other end 151 and the detachable regulation Structure 12 is connected.Here, the connection fixture 15 is by screwing and the Flexible Connector 14 and can Detachable adjustment structure 12 is connected, it is possible thereby to depth/length of the occluder for left auricle 1 is further adjusted, So as to preferably cause the occluder for left auricle 1 to adapt to different left auricle of heart depth.
In the other embodiment of the application, the end 150 can be buckle structure, meanwhile, the company The one end for connecing fixture 14 is also buckle structure, and the connection fixture 15 passes through the snap part and institute Flexible Connector 14 is stated to be fixedly connected.Here, the connection keeper 15 also it is solderable be connected to it is described detachable In formula adjustment structure 12.
Please continue to refer to Fig. 1, in the embodiment of the present application, the plugging structure 10 is a disc, described solid Determining structure 11 includes some hooks;In the other embodiment of the application, the fixed structure 11 can also For a disc, there are some hooks (as shown in Figure 4) on the disc.
The occupation mode of above-mentioned occluder for left auricle 1 is as follows:
The passage set up using occluder for left auricle conveying device by conduit leads the occluder for left auricle 1 To the end of conduit, in end release.When release, the fixed structure 11 first with hook goes out from sheath Come, it is ensured that suitable to stretch;After left auricle of heart cavity wall stationary positioned is good, detachable adjustment structure 12 with Out;Finally, plugging structure 10 is buckled in the oral area of left auricle of heart, fully laminating, reaches optimal closure effect Really.
When reclaiming, in the opposite direction, fixed structure 11 drives hook to be reclaimed naturally from the cavity wall of left auricle of heart. During concrete operations, the detachable adjustment structure 12 in the present embodiment can change the fixation of different size/size Structure 11, to adapt to different left auricle of heart structure, realizes and fixes;By adjustment fixing structure 11 with can The depth of position or detachable adjustment structure 12 itself between detachable adjustment structure 12 and then can be with Length/depth of occluder for left auricle is adjusted, different left auricle of heart depth are adapted to.
【Embodiment two】
The difference of the embodiment of the present application two and embodiment one is, the quantity of the Flexible Connector in embodiment one For one, and the quantity of the Flexible Connector in the present embodiment two is multiple.
Specifically, refer to Fig. 5, it is the use schematic diagram of multiple Flexible Connectors of the embodiment of the present invention two. As shown in figure 5, in the embodiment of the present application, the connection fixture 25 is two pieces of parallel flats, multiple bullets Property connector 24 is held in two pieces of parallel flats.It is preferred that, multiple Flexible Connectors 24 uniformly divide It is distributed in two pieces of parallel flats.
In the embodiment of the present application, each Flexible Connector 24 can be fixed on by fixed cell two pieces it is parallel flat In plate, for example, each Flexible Connector 24 is fixed in two pieces of parallel flats by screw nut.Specifically, Is structure is fixedly mounted in the two ends of the Flexible Connector 24, and centre is helical spring structure.Here, described The fixed installation structure at elastic connection year 24 two ends can be fixing hole, by screw through the fixing hole and One parallel flat, nut screws the screw, just can realize Flexible Connector 24 being fixed on and is connected On part 25.
Please continue to refer to Fig. 5, in the embodiment of the present application, a parallel flat is fixed on detachable adjustment structure On (not shown in Fig. 5), it is preferred that the center of a parallel flat and the detachable regulation Structure is connected;Another parallel flat is connected with the joint in plugging structure, it is preferred that this is another parallel The center of flat board is connected with the joint.
In the present embodiment two, the detachable adjustment structure is identical with embodiment one, described detachable Adjustment structure is also identical with embodiment one with the connected mode of fixed structure, and the present embodiment two is repeated no more to this.
【Embodiment three】
The difference of the embodiment of the present application three and embodiment one is, the detachable adjustment structure in embodiment one For screw nut structure, and the detachable adjustment structure in the present embodiment three is external splines internal spline structure.
Specifically, refer to Fig. 6, it is the structural representation of the detachable adjustment structure of the embodiment of the present invention three Figure.As shown in fig. 6, detachable adjustment structure 32 includes first component 320 and can be with described first The second component 321 that part 320 is separated or closed, first component 320 and the second component 321 energy Enough do relative motion, the first component 320 is connected with the plugging structure, the second component 321 with The fixed structure connection.Wherein, the first component 320 is outer/inner spline structure, the second component 321 be inside/outside spline structure.External splines internal spline structure centering and guidance quality are good, more tooth and groove, Couple stress more uniform;Because groove is shallower, stress concentration is smaller at tooth root, and strength reduction is less;The number of teeth compared with Many, total contact area is larger, thus can bear larger load.
In the present embodiment three, it can be adjusted by the insertion depth between external splines structure and internal spline structure Length/depth of occluder for left auricle, so as to adapt to different left auricle of heart depth.
Wherein, the connected mode between the detachable adjustment structure and Flexible Connector and fixed structure Embodiment one is referred to, the present embodiment three is repeated no more to this.
【Example IV】
The difference of the embodiment of the present application four and embodiment one is, the detachable adjustment structure in embodiment one For screw nut structure, and the detachable adjustment structure in the present embodiment four is buckle structure.
Specifically, refer to Fig. 7, it is the structural representation of the detachable adjustment structure of the embodiment of the present invention four Figure.As shown in fig. 7, detachable adjustment structure 42 includes first component 420 and can be with described first The second component 421 that part 420 is separated or closed, first component 420 and the second component 421 energy Enough do relative motion, the first component 420 is connected with the plugging structure, the second component 421 with The fixed structure connection.Wherein, the first component 420 is card and/buckling parts, the second component 421 For fastening/Ka Hebu.
In the present embodiment four, left auricle of heart can be adjusted by the insertion depth between card and portion and buckling parts and sealed Length/depth of stifled device, so as to adapt to different left auricle of heart depth.
Wherein, the connected mode between the detachable adjustment structure and Flexible Connector and fixed structure Embodiment one is referred to, the present embodiment four is repeated no more to this.
Foregoing description is only the description to present pre-ferred embodiments, not to any limit of the scope of the invention Calmly, the those of ordinary skill in field of the present invention does according to the disclosure above content any change, modification, belong to In the protection domain of claims.

Claims (8)

1. a kind of occluder for left auricle, the occluder for left auricle includes plugging structure and fixed structure, it is special Levy and be, the occluder for left auricle also includes:Detachable adjustment structure, it is described detachable Adjustment structure includes first component and second can separating or closing with the first component Part, the first component and the second component can do relative motion, the first component and institute Plugging structure connection is stated, the second component is connected with the fixed structure.
2. occluder for left auricle as claimed in claim 1, it is characterised in that the detachable regulation knot Structure is screw nut structure, external splines internal spline structure or buckle structure.
3. occluder for left auricle as claimed in claim 1, it is characterised in that the occluder for left auricle is also Including an at least Flexible Connector, the first component passes through the Flexible Connector and the closure Structure is connected.
4. occluder for left auricle as claimed in claim 3, it is characterised in that the occluder for left auricle is also Including connection fixture, one end of the connection fixture and one end of the Flexible Connector connect Connect, the other end of the connection fixture is connected with the detachable adjustment structure.
5. occluder for left auricle as claimed in claim 3, it is characterised in that the two of the Flexible Connector Hold as structure is fixedly mounted, centre is helical spring structure.
6. occluder for left auricle as claimed in claim 1, it is characterised in that the occluder for left auricle is also Including a joint, the joint is used to be connected with an occluder for left auricle conveying device.
7. occluder for left auricle as claimed in claim 1, it is characterised in that if the fixed structure includes Dry hook.
8. occluder for left auricle as claimed in claim 1, it is characterised in that the fixed structure is a dishful of There are some hooks on disk, the disc.
CN201610184108.XA 2016-03-28 2016-03-28 Left auricle plugging device Active CN107233115B (en)

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CN107233115B CN107233115B (en) 2020-01-24

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Publication number Priority date Publication date Assignee Title
CN110974315A (en) * 2019-11-19 2020-04-10 先健科技(深圳)有限公司 occluder
CN112137675A (en) * 2020-08-28 2020-12-29 河南科技大学第一附属医院 Left ventricle plugging device and using method
CN115998361A (en) * 2023-02-13 2023-04-25 潘湘斌 Heart treatment device
WO2024114271A1 (en) * 2022-11-30 2024-06-06 广东脉搏医疗科技有限公司 Left atrial appendage occluder

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CN204181678U (en) * 2014-10-13 2015-03-04 陈奕龙 Left atrial appendage occlusion system
CN104546054A (en) * 2015-01-19 2015-04-29 上海形状记忆合金材料有限公司 Adjustable plugging device and release method
CN204839624U (en) * 2015-06-15 2015-12-09 同济大学附属第十人民医院 Percutaneous left auricle of heart shutoff apparatus

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US20040044361A1 (en) * 1998-11-06 2004-03-04 Frazier Andrew G.C. Detachable atrial appendage occlusion balloon
CN102805654A (en) * 2011-06-01 2012-12-05 先健科技(深圳)有限公司 Occluder for left auricle
WO2015002625A1 (en) * 2013-07-02 2015-01-08 Bulent Oran The occluder device for cardiovascular system
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Publication number Priority date Publication date Assignee Title
CN110974315A (en) * 2019-11-19 2020-04-10 先健科技(深圳)有限公司 occluder
CN110974315B (en) * 2019-11-19 2021-07-20 先健科技(深圳)有限公司 occluder
CN112137675A (en) * 2020-08-28 2020-12-29 河南科技大学第一附属医院 Left ventricle plugging device and using method
WO2024114271A1 (en) * 2022-11-30 2024-06-06 广东脉搏医疗科技有限公司 Left atrial appendage occluder
CN115998361A (en) * 2023-02-13 2023-04-25 潘湘斌 Heart treatment device

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