AU5132096A - Glubodies - multiplicities of proteins capable of binding a variety of small molecules - Google Patents
Glubodies - multiplicities of proteins capable of binding a variety of small moleculesInfo
- Publication number
- AU5132096A AU5132096A AU51320/96A AU5132096A AU5132096A AU 5132096 A AU5132096 A AU 5132096A AU 51320/96 A AU51320/96 A AU 51320/96A AU 5132096 A AU5132096 A AU 5132096A AU 5132096 A AU5132096 A AU 5132096A
- Authority
- AU
- Australia
- Prior art keywords
- glubodies
- multiplicities
- binding
- variety
- small molecules
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 150000003384 small molecules Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0026—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5)
- C12N9/0028—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5) with NAD or NADP as acceptor (1.5.1)
- C12N9/003—Dihydrofolate reductase [DHFR] (1.5.1.3)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
- C07K14/42—Lectins, e.g. concanavalin, phytohaemagglutinin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
- C12N9/1088—Glutathione transferase (2.5.1.18)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Plant Pathology (AREA)
- Cell Biology (AREA)
- Botany (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38018895A | 1995-01-30 | 1995-01-30 | |
| US380188 | 1995-01-30 | ||
| PCT/US1996/001567 WO1996023879A1 (en) | 1995-01-30 | 1996-01-30 | Glubodies - multiplicities of proteins capable of binding a variety of small molecules |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU5132096A true AU5132096A (en) | 1996-08-21 |
Family
ID=23500246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU51320/96A Abandoned AU5132096A (en) | 1995-01-30 | 1996-01-30 | Glubodies - multiplicities of proteins capable of binding a variety of small molecules |
Country Status (2)
| Country | Link |
|---|---|
| AU (1) | AU5132096A (en) |
| WO (1) | WO1996023879A1 (en) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19742706B4 (en) * | 1997-09-26 | 2013-07-25 | Pieris Proteolab Ag | lipocalin muteins |
| DE69835531T2 (en) | 1997-11-12 | 2007-04-05 | Johnson & Johnson Pharmaceutical Research & Development, Llc | HIGH-PERFORMANCE RATE METHOD FOR THE FUNCTIONAL CLASSIFICATION OF PROTEINS IDENTIFIED IN A GENOMIC EXPERIMENTAL APPROACH |
| US6569631B1 (en) | 1998-11-12 | 2003-05-27 | 3-Dimensional Pharmaceuticals, Inc. | Microplate thermal shift assay for ligand development using 5-(4″dimethylaminophenyl)-2-(4′-phenyl)oxazole derivative fluorescent dyes |
| WO2003029462A1 (en) | 2001-09-27 | 2003-04-10 | Pieris Proteolab Ag | Muteins of human neutrophil gelatinase-associated lipocalin and related proteins |
| US7611847B2 (en) | 2005-06-01 | 2009-11-03 | Agency For Science, Technology And Research | Method for identifying an intestinal phenotype |
| JP2009526970A (en) | 2006-02-13 | 2009-07-23 | エージェンシー フォー サイエンス，テクノロジー アンド リサーチ | Method for processing biological or chemical samples |
| WO2007102785A1 (en) | 2006-03-09 | 2007-09-13 | Agency For Science, Technology And Research | Apparatus for performing a reaction in a droplet and method of using the same |
| US9874501B2 (en) | 2006-11-24 | 2018-01-23 | Curiox Biosystems Pte Ltd. | Use of chemically patterned substrate for liquid handling, chemical and biological reactions |
| WO2010120249A1 (en) | 2009-04-17 | 2010-10-21 | Curiox Biosystems Pte Ltd | Use of chemically patterned substrate for liquid handling, chemical and biological reactions |
| WO2008063135A1 (en) | 2006-11-24 | 2008-05-29 | Agency For Science, Technology And Research | Apparatus for processing a sample in a liquid droplet and method of using the same |
| US8663915B2 (en) | 2007-04-13 | 2014-03-04 | Agency For Science, Technology And Research | Methods of controlling tumorigenesis and diagnosing the risk thereof |
| WO2008136769A1 (en) | 2007-05-03 | 2008-11-13 | Nanyang Technological University | Online contaminant detection and removal system |
| SG150405A1 (en) | 2007-08-29 | 2009-03-30 | Agency Science Tech & Res | Method of coating a particle |
| WO2009058102A1 (en) | 2007-11-02 | 2009-05-07 | Agency For Science, Technology And Research | Methods and compounds for preventing and treating a tumour |
| WO2013114217A1 (en) | 2012-02-05 | 2013-08-08 | Curiox Biosystems Pte Ltd. | Array plates and methods for making and using same |
| US10725020B2 (en) | 2007-11-14 | 2020-07-28 | Curiox Biosystems Pte Ltd. | High throughput miniaturized assay system and methods |
| US9102920B2 (en) | 2008-05-06 | 2015-08-11 | Agency For Science, Technology And Research | Method of effecting de-differentiation of a cell |
| US9115340B2 (en) | 2008-08-08 | 2015-08-25 | Agency For Science Technology & Research | Microfluidic continuous flow device |
| WO2010044752A1 (en) | 2008-10-13 | 2010-04-22 | Agency For Science, Technology And Research | Amphiphilic polymers and nanocrystals coated therewith |
| US10464811B2 (en) | 2009-04-06 | 2019-11-05 | Nanyang Technological University | Method of forming a particulate porous metal oxide or metalloid oxide |
| CN102549427A (en) | 2009-07-07 | 2012-07-04 | 新加坡科技研究局 | Methods of identifying a pair of binding partners |
| US9549968B2 (en) | 2009-12-07 | 2017-01-24 | Pieris Pharmaceuticals Gmbh | Muteins of human lipocalin 2 (LcnC,hNGAL) with affinity for a given target |
| SG184345A1 (en) | 2010-03-31 | 2012-11-29 | Agency Science Tech & Res | Amphiphilic linear peptide/peptoid and hydrogel comprising the same |
| WO2012011877A2 (en) | 2010-07-23 | 2012-01-26 | Curiox Biosystems Pte Ltd | Apparatus and method for multiple reactions in small volumes |
| WO2013057096A1 (en) | 2011-10-17 | 2013-04-25 | Westfaelische Wilhelms-Universitaet Muenster | Assessment of pml risk and methods based thereon |
| CN106940268B (en) | 2012-02-23 | 2021-09-21 | 朱诺治疗有限公司 | Chromatographic separation of cells and other complex biological materials |
| EP2647995B8 (en) | 2012-04-02 | 2015-02-18 | Roche Diagnostics GmbH | Methods and use for assessing chronic obstructive pulmonary disease (COPD) severity |
| WO2013189521A1 (en) | 2012-06-19 | 2013-12-27 | Waclawczyk Simon | Method of generating cells of hepatocyte phenotype |
| EP2687850A1 (en) | 2012-07-19 | 2014-01-22 | Roche Diagniostics GmbH | Methods of stratifying for respiratory support therapy |
| US10179178B2 (en) | 2012-08-27 | 2019-01-15 | Nanyang Technology University | Nanoparticulate contrast agent |
| CN104662043B (en) | 2012-09-10 | 2019-10-18 | 明斯特大学 | Methods and compounds for preventing, treating and diagnosing inflammatory disorders |
| EP2972387A1 (en) | 2013-03-15 | 2016-01-20 | Westfälische Wilhelms-Universität Münster | Detection of acute renal allograft rejection |
| CA2891557A1 (en) | 2013-03-26 | 2014-05-22 | Pieris Ag | Novel specific-binding polypeptides and uses thereof |
| US9557318B2 (en) | 2013-07-09 | 2017-01-31 | Curiox Biosystems Pte Ltd. | Array plates for washing samples |
| AU2014294616B2 (en) | 2013-07-23 | 2019-07-11 | Biocon Limited | Use of a CD6 binding partner and method based thereon |
| US20160289270A1 (en) | 2013-11-18 | 2016-10-06 | Westfaelische Wilhelms-Universitaet Muenster | Methods, Peptides and Antibodies for Preventing, Treating and Diagnosing an Inflammatory Condition |
| EP3094650A2 (en) | 2014-01-13 | 2016-11-23 | Pieris Pharmaceuticals GmbH | Multi-specific polypeptide useful for localized tumor immunomodulation |
| LU92409B1 (en) | 2014-03-21 | 2015-09-22 | Philipps Universit T Marburg | Means and methods for itaconic acid production |
| CN106414724A (en) | 2014-04-16 | 2017-02-15 | 朱诺治疗有限公司 | Methods, kits and devices for expanding cell populations |
| CA2945414C (en) | 2014-04-30 | 2023-05-09 | Iba Gmbh | Method of isolating a target cell |
| AU2015261968B2 (en) | 2014-05-22 | 2018-11-22 | Pieris Pharmaceuticals Gmbh | Novel specific-binding polypeptides and uses thereof |
| US10526382B2 (en) | 2015-01-28 | 2020-01-07 | Pieris Pharmaceuticals Gmbh | Human neutrophil gelatinase-associated lipocalin (hNGAL) muteins capable of binding angiopoietin-2 (Ang-2) and methods of use thereof |
| WO2016166568A1 (en) | 2015-04-16 | 2016-10-20 | Juno Therapeutics Gmbh | Methods, kits and apparatus for expanding a population of cells |
| WO2016177802A1 (en) | 2015-05-04 | 2016-11-10 | Pieris Pharmaceuticals Gmbh | Anti-cancer fusion polypeptide |
| SG11201708339QA (en) | 2015-05-04 | 2017-11-29 | Pieris Pharmaceuticals Gmbh | Proteins specific for cd137 |
| EP4219535A1 (en) | 2015-05-18 | 2023-08-02 | Pieris Pharmaceuticals GmbH | Anti-cancer fusion polypeptide |
| CN107787327B (en) | 2015-05-18 | 2022-02-08 | 皮里斯制药有限公司 | Muteins of human lipocalin 2 having affinity for glypican-3 (GPC3) |
| US10545139B2 (en) | 2015-06-16 | 2020-01-28 | Curiox Biosystems Pte Ltd. | Methods and devices for performing biological assays using magnetic components |
| MA45488A (en) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | CELL CULTURE PROCESSES, KITS AND APPARATUS |
| MA45489A (en) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | CELL CULTURE PROCESSES, ASSOCIATED KITS AND APPARATUS |
| CN108474002B (en) | 2015-10-22 | 2023-05-23 | 朱诺治疗学有限公司 | Method, reagent cartridge, reagent and device for transduction |
| US10703810B2 (en) | 2015-11-30 | 2020-07-07 | Pieris Australia Pty Ltd. | Fusion polypeptides which bind vascular endothelial growth factor a (VEGF-A) and angiopoietin-2 (Ang-2) |
| TW201725212A (en) | 2015-12-10 | 2017-07-16 | 第一三共股份有限公司 | Novel proteins specific for calcitonin gene-related peptide |
| CN110709979B (en) | 2017-04-05 | 2024-04-09 | 科睿思生物科技(私人)有限公司 | Method, device and apparatus for cleaning samples on an array plate |
| US11866465B2 (en) | 2017-04-27 | 2024-01-09 | Juno Therapeutics Gmbh | Oligomeric particle reagents and methods of use thereof |
| WO2018202471A1 (en) | 2017-05-02 | 2018-11-08 | Bayer Aktiengesellschaft | Tmem16a modulation for diagnostic or therapeutic use in pulmonary hypertension (ph) |
| CN111344306A (en) | 2017-11-02 | 2020-06-26 | 拜耳股份公司 | Bispecific antibodies that bind ALK-1 and BMPR-2 |
| WO2020043693A1 (en) | 2018-08-29 | 2020-03-05 | Westfälische Wilhelms-Universität Münster | Diagnosis of multiple sclerosis |
| DE102018124022A1 (en) | 2018-09-28 | 2020-04-02 | Rheinisch-Westfälische Technische Hochschule (Rwth) Aachen | HYALURONIC ACID STABILIZER |
| CN113227358A (en) | 2018-10-31 | 2021-08-06 | 朱诺治疗学有限公司 | Method for selecting and stimulating cells and device for said method |
| BR112022008023A2 (en) | 2019-10-30 | 2022-07-12 | Juno Therapeutics Gmbh | CELL SELECTION AND/OR STIMULATION DEVICES AND USE METHODS |
| AU2021213439B2 (en) | 2020-01-31 | 2023-01-05 | Cell.Copedia GmbH | Methods of isolating a biological entity |
| KR20230135107A (en) | 2021-01-22 | 2023-09-22 | 바이엘 악티엔게젤샤프트 | LRRC15 antibody and conjugate thereof |
| WO2022207748A1 (en) | 2021-03-30 | 2022-10-06 | Westfälische Wilhelms-Universität Münster | Classification of neurological or psychiatric disease manifestations using multi-dimensional cerebrospinal fluid analysis |
| CN117916256A (en) | 2021-05-06 | 2024-04-19 | 朱诺治疗学有限公司 | Methods for stimulating and transducing T cells |
| WO2023017115A1 (en) | 2021-08-11 | 2023-02-16 | Iba Lifesciences Gmbh | Fractionation of cells based on a marker protein |
| EP4379375A1 (en) | 2022-12-01 | 2024-06-05 | Universität Münster | Classification of connective tissue disease with neurological manifestation using multi-dimensional peripheral blood analysis |
| WO2024200655A1 (en) | 2023-03-28 | 2024-10-03 | Westfälische Wilhelms-Universität Münster | Predictive level of pd-l1 on microvesicles in the evaluation whether being a responder to a treatment of nsclc |
| WO2025008404A1 (en) | 2023-07-04 | 2025-01-09 | Universitaet Regensburg In Vertretung Des Freistaates Bayern | Use of soluble cd46 concentration from peripheral blood as a parameter for the diagnosis of non-alcoholic fatty liver disease |
| WO2025040598A2 (en) | 2023-08-18 | 2025-02-27 | Immatics Biotechnologies Gmbh | Peptides displayed by mhc for use in immunotherapy against different types of cancer |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5096815A (en) * | 1989-01-06 | 1992-03-17 | Protein Engineering Corporation | Generation and selection of novel dna-binding proteins and polypeptides |
| CA2157929A1 (en) * | 1993-03-30 | 1994-10-13 | Lawrence M. Kauvar | Determination of concentration by affinity titration and competitive displacement in drug delivery |
-
1996
- 1996-01-30 AU AU51320/96A patent/AU5132096A/en not_active Abandoned
- 1996-01-30 WO PCT/US1996/001567 patent/WO1996023879A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO1996023879A1 (en) | 1996-08-08 |
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