AU2247599A - Process of making 3-aryloxy, 4-aryl furan-2-ones useful as inhibitors of cox-2 - Google Patents
Process of making 3-aryloxy, 4-aryl furan-2-ones useful as inhibitors of cox-2Info
- Publication number
- AU2247599A AU2247599A AU22475/99A AU2247599A AU2247599A AU 2247599 A AU2247599 A AU 2247599A AU 22475/99 A AU22475/99 A AU 22475/99A AU 2247599 A AU2247599 A AU 2247599A AU 2247599 A AU2247599 A AU 2247599A
- Authority
- AU
- Australia
- Prior art keywords
- cox
- aryloxy
- inhibitors
- making
- ones useful
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 101150071146 COX2 gene Proteins 0.000 title 1
- 101100114534 Caenorhabditis elegans ctc-2 gene Proteins 0.000 title 1
- 101150000187 PTGS2 gene Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/60—Two oxygen atoms, e.g. succinic anhydride
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6069497P | 1997-09-24 | 1997-09-24 | |
| US60/060694 | 1997-09-24 | ||
| GBGB9815805.8A GB9815805D0 (en) | 1998-07-21 | 1998-07-21 | Chemical process |
| GB9815805 | 1998-07-21 | ||
| PCT/US1998/019642 WO1999015513A1 (en) | 1997-09-24 | 1998-09-21 | Process of making 3-aryloxy, 4-aryl furan-2-ones useful as inhibitors of cox-2 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2247599A true AU2247599A (en) | 1999-04-12 |
Family
ID=26314074
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU22475/99A Abandoned AU2247599A (en) | 1997-09-24 | 1998-09-21 | Process of making 3-aryloxy, 4-aryl furan-2-ones useful as inhibitors of cox-2 |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1017687A4 (en) |
| JP (1) | JP3516658B2 (en) |
| CN (1) | CN1271352A (en) |
| AU (1) | AU2247599A (en) |
| EA (1) | EA002690B1 (en) |
| SK (1) | SK4202000A3 (en) |
| WO (1) | WO1999015513A1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2401697A1 (en) | 2000-03-03 | 2001-09-07 | Pfizer Products Inc. | Pyrazole ether derivatives as anti-inflammatory/analgesic agents |
| PL359556A1 (en) | 2000-07-20 | 2004-08-23 | Lauras As | Method - use of cox-2 inhibitors for preventing immunodeficiency |
| CN118164933B (en) * | 2024-04-10 | 2025-04-08 | 辽宁中医药大学 | Furan new compound in purslane, and extraction and separation method and application thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5352832A (en) * | 1992-12-18 | 1994-10-04 | Schering Corporation | Asymmetric process for preparing florfenicol, thiamphenicol chloramphenicol and oxazoline intermediates |
| US5393790A (en) * | 1994-02-10 | 1995-02-28 | G.D. Searle & Co. | Substituted spiro compounds for the treatment of inflammation |
| UA57002C2 (en) * | 1995-10-13 | 2003-06-16 | Мерк Фросст Кенада Енд Ко./Мерк Фросст Кенада Енд Сі. | (methylsulfonyl)phenyl-2-(5n)-furanon derivative, a pharmaceutical composition and a method for treatment |
| US5789413A (en) * | 1996-02-01 | 1998-08-04 | Merck Frosst Canada, Inc. | Alkylated styrenes as prodrugs to COX-2 inhibitors |
-
1998
- 1998-09-21 CN CN98809463A patent/CN1271352A/en active Pending
- 1998-09-21 WO PCT/US1998/019642 patent/WO1999015513A1/en not_active Application Discontinuation
- 1998-09-21 JP JP2000512820A patent/JP3516658B2/en not_active Expired - Fee Related
- 1998-09-21 EA EA200000350A patent/EA002690B1/en not_active IP Right Cessation
- 1998-09-21 AU AU22475/99A patent/AU2247599A/en not_active Abandoned
- 1998-09-21 EP EP98947177A patent/EP1017687A4/en not_active Withdrawn
- 1998-09-21 SK SK420-2000A patent/SK4202000A3/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1017687A1 (en) | 2000-07-12 |
| CN1271352A (en) | 2000-10-25 |
| WO1999015513A1 (en) | 1999-04-01 |
| EA002690B1 (en) | 2002-08-29 |
| JP2001517661A (en) | 2001-10-09 |
| SK4202000A3 (en) | 2000-10-09 |
| EA200000350A1 (en) | 2000-10-30 |
| EP1017687A4 (en) | 2001-10-31 |
| JP3516658B2 (en) | 2004-04-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |