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AR016681A1 - Deplecion de celulas th2; composiciones; metodos - Google Patents

Deplecion de celulas th2; composiciones; metodos

Info

Publication number
AR016681A1
AR016681A1 ARP980105731A ARP980105731A AR016681A1 AR 016681 A1 AR016681 A1 AR 016681A1 AR P980105731 A ARP980105731 A AR P980105731A AR P980105731 A ARP980105731 A AR P980105731A AR 016681 A1 AR016681 A1 AR 016681A1
Authority
AR
Argentina
Prior art keywords
cells
compositions
depection
methods
ccr8
Prior art date
Application number
ARP980105731A
Other languages
English (en)
Original Assignee
Schering Corp
Napolitano Monica
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp, Napolitano Monica filed Critical Schering Corp
Publication of AR016681A1 publication Critical patent/AR016681A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7158—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for chemokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Se proporcionan composiciones de union que se unen selectivamente a un marcador específicamente encontrado en las células Th2 y varios métodos de uso delas composiciones de union. En particular, el método hace uso del hecho que el receptor CCR8 dequ emoquina se expresa selectivamente en el subconjunto decélulas Th2. Preferentemente, la composicion de union es un anticuerpo monoclonal específico para CCR8.
ARP980105731A 1997-11-13 1998-11-12 Deplecion de celulas th2; composiciones; metodos AR016681A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6539297P 1997-11-13 1997-11-13

Publications (1)

Publication Number Publication Date
AR016681A1 true AR016681A1 (es) 2001-07-25

Family

ID=22062409

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP980105731A AR016681A1 (es) 1997-11-13 1998-11-12 Deplecion de celulas th2; composiciones; metodos

Country Status (7)

Country Link
EP (1) EP1030865A2 (es)
JP (1) JP2001523446A (es)
AR (1) AR016681A1 (es)
AU (1) AU1373099A (es)
CA (1) CA2309761A1 (es)
WO (1) WO1999025734A2 (es)
ZA (1) ZA9810371B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7157418B1 (en) 1998-07-22 2007-01-02 Osprey Pharmaceuticals, Ltd. Methods and compositions for treating secondary tissue damage and other inflammatory conditions and disorders
US6416954B1 (en) * 1999-02-08 2002-07-09 Schering Corporation Modulating Th2 cell levels via vMIP-I/CCR8 interaction
US6762341B2 (en) 2000-02-10 2004-07-13 Schering Corporation Uses of mammalian CCR8 receptors and related reagents
WO2001058484A2 (en) * 2000-02-10 2001-08-16 Schering Corporation Novel uses of mammalian ccr8 receptors and related reagents
WO2003096020A2 (en) * 2002-05-13 2003-11-20 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with chemokine receptor 8 (ccr8)
WO2007044756A2 (en) * 2005-10-11 2007-04-19 Icos Corporation Monoclonal antibodies recognizing human ccr8
WO2014082993A2 (en) * 2012-11-30 2014-06-05 Galapagos Nv Molecular targets and compounds, and methods to identify the same, useful in the down-regulation of the th2 response
MX395142B (es) * 2016-05-16 2025-03-25 Checkmab S R L Marcadores selectivamente desregulados en celulas t reguladoras, infiltrantes de tumores.
WO2020138489A1 (ja) * 2018-12-27 2020-07-02 塩野義製薬株式会社 新規抗ｃｃｒ８抗体
CA3169451A1 (en) 2020-02-14 2021-08-19 Jounce Therapeutics, Inc. Antibodies and fusion proteins that bind to ccr8 and uses thereof
WO2023219147A1 (ja) * 2022-05-13 2023-11-16 塩野義製薬株式会社 Ｃｃｒ８検出用新規抗ｃｃｒ８抗体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4364932A (en) * 1979-09-18 1982-12-21 Ortho Pharmaceutical Corporation Monoclonal antibody to human cytotoxic and suppressor T cells and methods of preparing same
EP0843557B1 (en) * 1995-07-21 2002-11-13 Applied Research Systems ARS Holding N.V. Methods for detecting, identifying, isolating, and selectively labelling and targeting th1 lymphocytes by means of the lag-3 protein
JP3144805B2 (ja) * 1996-06-05 2001-03-12 株式会社 ビー・エム・エル ヒトＴｈ２特異的タンパク質及びこれをコードする遺伝子（Ｂ１９）並びにこれに関連する形質転換体、組換えベクター及びモノクローナル抗体

Also Published As

Publication number Publication date
ZA9810371B (en) 1999-08-30
EP1030865A2 (en) 2000-08-30
WO1999025734A3 (en) 1999-07-15
AU1373099A (en) 1999-06-07
JP2001523446A (ja) 2001-11-27
WO1999025734A2 (en) 1999-05-27
CA2309761A1 (en) 1999-05-27

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