Aonuma et al., 2021 - Google Patents
Effect of aging on bone metabolism: the involvement of complement C1qAonuma et al., 2021
View PDF- Document ID
- 17294213230648690774
- Author
- Aonuma F
- Higashi S
- Tsuka S
- Ohsumi T
- Masaki C
- Hosokawa R
- Takeuchi H
- Publication year
- Publication venue
- Journal of Prosthodontic Research
External Links
Snippet
Purpose Impairment of normal bone remodeling affects the successful osseointegration of dental implants. Recently, it has been reported that complement C1q level increases with age and delays wound healing by modulating Wnt signaling. As Wnt signaling is known to …
- 230000032683 aging 0 title abstract description 5
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Behera et al. | Hydrogen sulfide epigenetically mitigates bone loss through OPG/RANKL regulation during hyperhomocysteinemia in mice | |
| El Boustany et al. | Capacitative calcium entry and transient receptor potential canonical 6 expression control human hepatoma cell proliferation | |
| Lu et al. | Nesfatin-1 functions as a switch for phenotype transformation and proliferation of VSMCs in hypertensive vascular remodeling | |
| Zhang et al. | The PERK-EIF2α-ATF4 signaling branch regulates osteoblast differentiation and proliferation by PTH | |
| Yu et al. | Wnt4 signaling prevents skeletal aging and inflammation by inhibiting nuclear factor-κB | |
| AU2006320670B8 (en) | Methods for the treatment of muscle loss | |
| Raymond et al. | Apoptosis of endothelial cells triggers a caspase‐dependent anti‐apoptotic paracrine loop active on vascular smooth muscle cells | |
| Kim et al. | TRIM38 regulates NF-κB activation through TAB2 degradation in osteoclast and osteoblast differentiation | |
| Wu et al. | Regulation of bone homeostasis: signaling pathways and therapeutic targets | |
| Hsiao et al. | Kinsenoside prevents ovariectomy-induced bone loss and suppresses osteoclastogenesis by regulating classical NF-κB pathways | |
| Kim et al. | DA-1241, a novel GPR119 agonist, improves hyperglycaemia by inhibiting hepatic gluconeogenesis and enhancing insulin secretion in diabetic mice | |
| Basak et al. | Molecular regulation of trophoblast stem cell self-renewal and giant cell differentiation by the Hippo components YAP and LATS1 | |
| Yue et al. | Tiam1 mediates Rac1 activation and contraction‐induced glucose uptake in skeletal muscle cells | |
| Aonuma et al. | Effect of aging on bone metabolism: the involvement of complement C1q | |
| Liu et al. | Belumosudil, ROCK2-specific inhibitor, alleviates cardiac fibrosis by inhibiting cardiac fibroblasts activation | |
| Liu et al. | The effects of tranylcypromine on osteoclastogenesis in vitro and in vivo | |
| Lu et al. | Pax2 is essential for proliferation and osteogenic differentiation of mouse mesenchymal stem cells via Runx2 | |
| Zhao et al. | A CEBPB/miR-32–5p/GATA6 axis promotes vascular calcification in type 2 diabetes | |
| Liu et al. | C1q/TNF-related protein 3 alleviates heart failure via attenuation of oxidative stress in myocardial infarction rats | |
| Zhao et al. | ST1926 attenuates steroid‐induced osteoporosis in rats by inhibiting inflammation response | |
| CN112423773A (en) | Treatment and biomarkers for prognosis of Zika virus infection | |
| Bolamperti et al. | Evidence for altered canonical Wnt signaling in the trabecular bone of elderly postmenopausal women with fragility femoral fracture | |
| Park et al. | Unveiling the potential effects of acetylsalicylic acid: insights into regeneration in endometrial stem cells | |
| Tsai et al. | Rosiglitazone inhibits monocyte/macrophage adhesion through de novo adiponectin production in human monocytes | |
| Li et al. | NEK2 promotes the progression of osteoarthritis by stabilizing ATF2 through phosphorylation at Ser-112 and inhibiting autophagy |