Chen et al., 2019 - Google Patents
Simultaneous determination of selegiline, desmethylselegiline, R/S-methamphetamine, and R/S-amphetamine on dried urine spots by LC/MS/MS: Application to a …Chen et al., 2019
View HTML- Document ID
- 12127109506667165146
- Author
- Chen L
- Yu Y
- Duan G
- Wang X
- Shen B
- Xiang P
- Publication year
- Publication venue
- Frontiers in Chemistry
External Links
Snippet
Objective: Chiral analysis is a crucial method to differentiate selegiline intake from drug abuse. A dried urine spot (DUS) analytical method based on spotting urine samples (10 μL) onto dried spot collection cards, and followed by air-drying and extraction, was developed …
- 210000002700 Urine 0 title abstract description 63
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/90—Plate chromatography, e.g. thin layer or paper chromatography
- G01N30/94—Development
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Sadones et al. | Spot them in the spot: analysis of abused substances using dried blood spots | |
| Chen et al. | Simultaneous determination of selegiline, desmethylselegiline, R/S-methamphetamine, and R/S-amphetamine on dried urine spots by LC/MS/MS: Application to a pharmacokinetic study in urine | |
| Cao et al. | Simultaneous quantitation of 78 drugs and metabolites in urine with a dilute-and-shoot LC–MS-MS assay | |
| Macwan et al. | Development and validation of a sensitive, simple, and rapid method for simultaneous quantitation of atorvastatin and its acid and lactone metabolites by liquid chromatography-tandem mass spectrometry (LC-MS/MS) | |
| Fagiola et al. | Screening of novel psychoactive substances in postmortem matrices by liquid chromatography–tandem mass spectrometry (LC–MS-MS) | |
| Khelfi et al. | Determination of Chlorpromazine, Haloperidol, Levomepromazine, Olanzapine, Risperidone, and Sulpiride in Human Plasma by Liquid Chromatography/Tandem Mass Spectrometry (LC‐MS/MS) | |
| Ingels et al. | Determination of gamma-hydroxybutyric acid in dried blood spots using a simple GC-MS method with direct “on spot” derivatization | |
| Meesters et al. | Ultrafast and high-throughput mass spectrometric assay for therapeutic drug monitoring of antiretroviral drugs in pediatric HIV-1 infection applying dried blood spots | |
| Pablo et al. | Automated analysis of dried urine spot (DUS) samples for toxicology screening | |
| Beck et al. | Methods for urine drug testing using one-step dilution and direct injection in combination with LC–MS/MS and LC–HRMS | |
| Li et al. | Simultaneous LC–MS/MS quantitation of acetaminophen and its glucuronide and sulfate metabolites in human dried blood spot samples collected by subjects in a pilot clinical study | |
| Li et al. | Dried blood spots as a sampling technique for the quantitative determination of guanfacine in clinical studies | |
| Mulet et al. | Comprehensive analysis of synthetic cannabinoids and metabolites in oral fluid by online solid-phase extraction coupled to liquid chromatography-triple quadrupole-mass spectrometry | |
| Lu et al. | An LC-MS/MS method for the simultaneous determination of 18 antibacterial drugs in human plasma and its application in therapeutic drug monitoring | |
| Tomková et al. | Analysis of selected designer benzodiazepines by ultra high performance liquid chromatography with high‐resolution time‐of‐flight mass spectrometry and the estimation of their partition coefficients by micellar electrokinetic chromatography | |
| Coulter et al. | Analysis of drugs in oral fluid using LC-MS/MS | |
| Sadones et al. | Microwave-assisted on-spot derivatization for gas chromatography–mass spectrometry based determination of polar low molecular weight compounds in dried blood spots | |
| da Silva et al. | Determination of cannabinoids in plasma using salting‐out‐assisted liquid–liquid extraction followed by LC–MS/MS analysis | |
| Guo et al. | Liquid chromatography with tandem mass spectrometric method for determination of 425 drugs and poisons in dried blood spots and application to forensic cases | |
| Smith et al. | A new broad-spectrum drug screen for 127 analytes by LC-MS/MS | |
| Di Trana et al. | QuEChERS extraction and simultaneous quantification in GC-MS/MS of hexahydrocannabinol epimers and their metabolites in whole blood, urine, and oral fluid | |
| Jafari et al. | Microextraction techniques in antibiotic monitoring in body fluids: Recent trends and future | |
| Beck et al. | Biomarkers to disclose recent intake of alcohol: potential of 5-hydroxytryptophol glucuronide testing using new direct UPLC-tandem MS and ELISA methods | |
| Robbins et al. | A Human Oral Fluid Assay for D‐and L-Isomer Detection of Amphetamine and Methamphetamine Using Liquid‐Liquid Extraction | |
| Gorziza et al. | Study of Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) extraction FROM dried oral fluid spots (DOFS) and LC–MS/MS detection |