Parrondo et al., 2023 - Google Patents
IRAK-4 inhibition: emavusertib for the treatment of lymphoid and myeloid malignanciesParrondo et al., 2023
View HTML- Document ID
- 11714496491621457681
- Author
- Parrondo R
- Iqbal M
- Von Roemeling R
- Von Roemeling C
- Tun H
- Publication year
- Publication venue
- Frontiers in immunology
External Links
Snippet
Several studies have identified mutations in the MYD88L265P gene as a key driver mutation in several B-cell lymphomas. B-cell lymphomas that harbor the MYD88L265P mutation form a complex with phosphorylated Bruton's tyrosine kinase (BTK) and are responsive to BTK …
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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