Automated cell properties toolbox from 3D bioprinted hydrogel scaffolds via deep learning and optical coherence tomography

Mahdi Babaei, Aaron Shamouil, Jiaying Wang, Deepak Khare, Tianyuanye Wang, Meijie Shih, Xiaojun Yu, and Yu Gan

Biomed. Opt. Express 16(5), 2061-2076 (2025)  View: HTML | PDF

Visible light optical coherence tomography for assessing retinal structure and function in diseased mouse models

Qianyue Gu, Wenbo Xiu, Songzhi Wu, Kaiwen Li, Baihan Li, Zhenfei Tang, Chenlu Yan, Xiaogang Wang, Chong He, Fang Lu, and Zhao Wang

Biomed. Opt. Express 16(5), 2077-2092 (2025)  View: HTML | PDF | Compressed PDF

Advanced 3D retinal lesion segmentation using channel-spatial attention-guided multi-scale feature aggregation

Guangming Ni, Kaizhi Cao, Xiaoyang Qin, Xinhao Zeng, Renxiong Wu, Ling Wan, Jie Zhong, and Yong Liu

Biomed. Opt. Express 16(5), 2093-2110 (2025)  View: HTML | PDF

Quantitative photoacoustic imaging algorithm using sparse decomposition for photoacoustic and ultrasound dual-mode imaging

Yang Liu, Boheng Zhang, Yiming Ma, Zezheng Qin, and Mingjian Sun

Biomed. Opt. Express 16(5), 1752-1772 (2025)  View: HTML | PDF

Enhancing the pathological diagnosis of oral cancers using broadband ultraviolet photoacoustic microscopy

Li Zhang, Fan Yang, Jianwei Shang, Yong Yang, Siwei Zhu, Xiaojing Wu, Zhengduo Yang, Yingbin Yan, Jun Shen, and Xiaocong Yuan

Biomed. Opt. Express 16(5), 1971-1987 (2025)  View: HTML | PDF

Whole retina light-evoked optoretinography (ORG) under different retina hydration levels: modeling of Bruch’s membrane ORGs

Pengfei Zhang, Sarah J. Karlen, Gabriel P. Allina, and Robert J. Zawadzki

Biomed. Opt. Express 16(5), 1944-1959 (2025)  View: HTML | PDF  [Suppl. Mat. (3)]

Eliminating the influence of head and eye movements on the estimation of tear film surface parameters in lateral shearing interferometry

Dorota H. Szczesna-Iskander and D. Robert Iskander

Biomed. Opt. Express 16(5), 1835-1842 (2025)  View: HTML | PDF

Ultrafast laser bone ablation towards high surgical speeds and clinically relevant operation times for spine surgeries

Biswajit Mishra, Liam Andrus, Aditya Roy, Berk Camli, Fetah Benabid, and Adela Ben-Yakar

Biomed. Opt. Express 16(5), 1871-1886 (2025)  View: HTML | PDF  [Suppl. Mat. (1)]

Machine learning-based method to detect capillary stalling using optical coherence tomography

Joshua Assi, Sabina Stefan, Rockwell Tang, Gülce Küreli, Sreekanth Kura, Emily Long, John Jiang, David Boas, and Jonghwan Lee

Biomed. Opt. Express 16(5), 1807-1818 (2025)  View: HTML | PDF  [Suppl. Mat. (1)]

A-scan sequence transformers for palpation with optical coherence elastography

Robin Mieling, Maximilian Neidhardt, Finn Behrendt, Sarah Latus, Axel Heinemann, Benjamin Ondruschka, and Alexander Schlaefer

Biomed. Opt. Express 16(5), 1925-1943 (2025)  View: HTML | PDF

gcDLSeg: integrating graph-cut into deep learning for binary semantic segmentation

Hui Xie, Weiyu Xu, Ya Xing Wang, John Buatti, and Xiaodong Wu

Biomed. Opt. Express 16(5), 1999-2019 (2025)  View: HTML | PDF

Enhancing ultra-high density single-molecule localization with deep spatiotemporal networks

Fei Deng, Tailong Chen, Yuyuan Qiao, Jixiang Ding, Yiqing Zhang, Lirong Qiu, Weiqian Zhao, Jianli Liu, and Fan Xu

Biomed. Opt. Express 16(5), 1773-1791 (2025)  View: HTML | PDF  [Suppl. Mat. (1)]

Fast interrogation of intestinal organ-on-chip devices through inverted single-plane illumination microscopy (iSPIM) using an electro-tunable lens

Emilio J. Gualda, Aina Abad-Lázaro, Gizem Altay, Gustavo Castro-Olvera, Matteo Bernardello, Vanesa Fernández-Majada, Elena Martínez, and Pablo Loza-Álvarez

Biomed. Opt. Express 16(5), 2020-2032 (2025)  View: HTML | PDF  [Suppl. Mat. (7)]

Four-modal device comprising optical coherence tomography, photoacoustic tomography, ultrasound, and Raman spectroscopy developed for in vivo skin lesion assessment

Anatoly Fedorov Kukk, Di Wu, Rüdiger Panzer, Steffen Emmert, and Bernhard Roth

Biomed. Opt. Express 16(5), 1792-1806 (2025)  View: HTML | PDF

Analysis of the key signaling pathway of baicalin that induces autophagy in papillary thyroid cancer via an optical resonator

Yi Lai, Dan Ru, Chenhuan Ding, Chen Wang, Ling Ding, Cenxin Luo, Yujie Qi, Xianfeng Chen, Hailang Dai, and He Li

Biomed. Opt. Express 16(5), 1843-1855 (2025)  View: HTML | PDF  [Suppl. Mat. (1)]

Single-shot full-field optical coherence tomography with a single polarization camera

Ahyeon Hur, Sucbei Moon, Young-Wan Choi, and Woo June Choi

Biomed. Opt. Express 16(5), 1960-1970 (2025)  View: HTML | PDF  [Suppl. Mat. (5)]

Ultrafast line-field holographic elastography with single excitation for corneal biomechanical characterization

Kexin Shen, Xingyu Zhou, Qingying Wang, Cheng Lu, Kaixi Zheng, Ni Wan, Fan Lu, and Dexi Zhu

Biomed. Opt. Express 16(5), 1887-1898 (2025)  View: HTML | PDF

Nanozyme-active Au@Pt NRs array SERS platform based on a recognition competition strategy for convenient and ultrasensitive detection of miR-106a-5p associated with cerebral infarction

Binbin Zeng, Huaiwu Fu, Cong Wu, Xudong Zhang, Tianran Li, Qiong Xu, Yayun Qian, and Ruirui Yang

Biomed. Opt. Express 16(5), 2033-2046 (2025)  View: HTML | PDF  [Suppl. Mat. (1)]

Diode-based photoacoustic imaging for monitoring therapeutic response in rheumatoid arthritis

Maurice Retout, Lubna Amer, Elizabeth Thompson, William Penny, Brian Pedersen, and Jesse Jokerst

Biomed. Opt. Express 16(5), 1899-1908 (2025)  View: HTML | PDF  [Suppl. Mat. (1)]

Non-ergodicity and noise-corrected diffuse speckle contrast analysis in deep tissue blood flow measurement

Jiachi Hong, Wenting Zhu, Bowen Zhao, Pengcheng Li, and Jinling Lu

Biomed. Opt. Express 16(5), 1856-1870 (2025)  View: HTML | PDF  [Suppl. Mat. (1)]

Scaling up X-ray holographic nanotomography for neuronal tissue imaging

Jayde Livingstone, Carles Bosch, Aaron T. Kuan, Lucas Benoït, Paolo Busca, Thierry Martin, Mohd F. E. B. Mazri, Wangchu Xiang, Wei-Chung Allen Lee, Andreas T. Schaefer, Peter Cloetens, and Alexandra Pacureanu

Biomed. Opt. Express 16(5), 2047-2060 (2025)  View: HTML | PDF

Efficient, broadly-tunable, hollow-fiber source of megawatt pulses for multiphoton microscopy: erratum

Yishai Eisenberg, Wenchao Wang, Shitong Zhao, Eric S. Hebert, Yi-Hao Chen, Dimitre G. Ouzounov, Hazuki Takahashi, Anna Gruzdeva, Aaron K. LaViolette, Moshe Labaz, Pavel Sidorenko, Enrique Antonio-Lopez, Rodrigo Amezcua-Correa, Nilay Yapici, Chris Xu, and Frank Wise

Biomed. Opt. Express 16(5), 2111-2111 (2025)  View: HTML | PDF