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Endocrinology & Metabolism news
Medications
Routine use of metabolic drug recommended for all kidney function levels
The results of two large-scale studies demonstrate that sodium-glucose co-transporter 2 (SGLT2) inhibitors significantly reduce the risk of kidney disease progression, hospitalization, and death in people with and without ...
21 hours ago
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Diseases, Conditions, Syndromes
Study uncovers glomerular disease outcomes across the lifespan
New research reveals that contrary to conventional belief, primary glomerular diseases are not necessarily benign for children and young adults. In fact, some subsets of children and young adults may experience faster kidney ...
22 hours ago
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Disagreement between two kidney function tests predicts serious health problems
A mismatch between two common tests for kidney function may indicate a higher risk for kidney failure, heart disease, and death, a new study shows.
Nov 7, 2025
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Urolithin A nudges aging immune cells toward a youthful profile in 28 days
An international research team focused on aging reports that urolithin A at 1,000 mg per day shifted human immune profiles toward a more naive-like, less exhausted CD8+ state and increased fatty acid oxidation capacity, with ...
Glycosylation enzyme selectivity in mouse kidneys shows promise for future disease research
Glycans are important complex carbohydrates found on cell surfaces that serve crucial roles in cell-to-cell communication, structure, and protection. They are attached to many proteins in the body, and their attachment differs ...
Nov 7, 2025
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Why morning exercise feels so hard
Your alarm goes off. Somehow you manage to get dressed, drag yourself to the gym, and start squatting.
Nov 7, 2025
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Why your daily walk might not work as well if you're on metformin
A widely prescribed diabetes drug may be sabotaging one of the most trusted strategies for preventing the disease: exercise.
Nov 6, 2025
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Metabolic scarring during TB treatment highlights need for nutrition support, study says
A new study published in PLOS Global Public Health contributes to the growing evidence that nutrition should be treated as a core part of tuberculosis care—not an afterthought.
Nov 6, 2025
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Widely used pesticides may lower sperm count
Contemporary agricultural practices make it difficult to prevent consuming chemicals and potentially causing harm to the body.
Nov 6, 2025
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Urinary albumin-creatinine ratio better measures risk for kidney failure
The urinary albumin-creatinine ratio (UACR) is more strongly associated with kidney failure than the urinary protein-creatinine ratio (UPCR), according to research published online Nov. 4 in the Annals of Internal Medicine.
Nov 6, 2025
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Missing enzyme may explain impaired bone growth
Chondrocytes play a crucial role in skeletal development. Many bones, such as those in the arms and legs, are formed through endochondral ossification, in which chondrocytes assemble to create a cartilage scaffold that is ...
Nov 6, 2025
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Human stomach cells tweaked to produce insulin in diabetes treatment study
Type 1 diabetes is caused by an insufficient production of the hormone insulin by cells in the pancreas called beta cells and is estimated to affect 9.5 million people worldwide.
Nov 6, 2025
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Q&A: Managing menopause after cancer
Menopause can bring a wave of physical and emotional changes—and for people with cancer, those changes can start earlier or feel more intense. Treatments like chemotherapy, radiation, surgery, and/or endocrine therapy can ...
Nov 6, 2025
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Insights from worms could help scientists harness the power of dietary restriction for longevity
The pursuit of a longer life may currently be trending for tech bros, but the notion of a fountain of youth, or even immortality, has intrigued people for millennia. Yet, some of the more evidence-based methods to increase ...
Nov 5, 2025
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Missing a common protein could affect how muscles respond to testosterone
Lacking a common protein may affect how muscles respond to testosterone, potentially affecting athletic performance and age-related muscle loss, according to a new study.
Nov 5, 2025
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Triggering cell death in metastatic melanoma may pave the way for new cancer treatments
Metastatic melanoma cells that have spread to lymph nodes survive by relying on a protein called ferroptosis suppressor protein 1 (FSP1)—a surprising metabolic dependency that could open the door to a new class of cancer ...
Nov 5, 2025
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Alzheimer's can hijack communication between brain and fat tissue, potentially worsening metabolic health
A study from Houston Methodist sheds light on how Alzheimer's disease may contribute to larger health issues by hijacking the body's ability to regulate its metabolism.
Nov 5, 2025
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Chaperone-mediated autophagy prevents loss of brown adipose tissue activity during aging
As the body ages, brown adipose tissue activity decreases, fewer calories are burned, and this can contribute to obesity and certain chronic cardiovascular diseases that worsen with age.
Nov 5, 2025
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Yes, you can be intolerant to fruit and veg
For most people, eating a wide variety of fruit and vegetables is the cornerstone of a healthy diet.
Nov 5, 2025
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New research challenges simplistic views on detransition
As access to gender-affirming care has expanded in recent years, public and clinical understandings of gender transition and detransition have remained limited and highly politicized. Anecdotal reports of detransition have ...
Nov 5, 2025
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Therapies against cellular aging may help treat metabolic diseases
A growing body of evidence implicates cellular senescence—when cells age and permanently stop dividing—as an important contributor to metabolic dysfunction that can lead to obesity, type 2 diabetes, and metabolic syndrome.
Nov 5, 2025
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Study pinpoints source of free radicals in the brain that may fuel dementia
Free radicals generated at a specific site in non-neuronal brain cells called astrocytes may promote dementia, according to a Weill Cornell Medicine study. These findings, published in Nature Metabolism, demonstrated that ...
Nov 4, 2025
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Time-restricted eating without calorie cuts doesn't improve metabolic health, study finds
Contrary to common assumptions, a new study from the German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE) and Charité—Universitätsmedizin Berlin shows that intermittent fasting (time-restricted eating) with an ...
Nov 4, 2025
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Minimal drug fragment disables cancer cells' antioxidant defenses, offering hope for hard-to-treat tumors
Scientists at Wake Forest University School of Medicine have discovered a new way to kill cancer cells by blocking their ability to clean up harmful waste. Cancer cells produce high levels of hydrogen peroxide, which can ...
Nov 4, 2025
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Real-time glucose monitoring with professional support can improve type 1 diabetes control
People with type 1 diabetes achieved significantly better long-term blood glucose when their levels were monitored by health care professionals in real time, via a sensor under the skin, and they received regular advice in ...
Nov 4, 2025
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