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Top news stories for the week 45

Monday, Nov 03

Antibody therapy foils pancreatic cancer's sugar-based disguise to reawaken immune system

Pancreatic cancer is notoriously hard to treat and often resists the most advanced immunotherapies. Northwestern Medicine scientists have uncovered a novel explanation for that resistance: Pancreatic tumors use a sugar-based ...

Nov 3, 2025

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Neural implant smaller than a grain of salt can wirelessly track brain

Cornell University researchers and collaborators have developed a neural implant so small that it can rest on a grain of salt, yet it can wirelessly transmit brain activity data in a living animal for more than a year.

Nov 3, 2025

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106

Holographic optogenetics could enable faster brain mapping for new discoveries

Recent technological advances have opened new possibilities for neuroscience research, allowing researchers to map the brain's structure and synaptic connectivity (i.e., the junctions via which neurons communicate with each ...

Nov 3, 2025 feature

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Protein plays unexpected dual role in protecting brain from oxidative stress damage

New research from Johns Hopkins Medicine shows that the enzyme biliverdin reductase A (BVRA) plays a direct protective role against oxidative stress in neurons, independent of its role producing the yellow pigment bilirubin.

Nov 3, 2025

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Waist-to-height ratio outperforms BMI in predicting heart disease risk

The ratio of a person's waist measurement compared to their height is more reliable than body mass index (BMI) at predicting heart disease risk, according to new research from UPMC and University of Pittsburgh physician-scientists.

Nov 3, 2025

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Even modest amounts of physical activity may slow Alzheimer's disease among at-risk older adults

Increasing your steps by even a little bit may help slow down the progression of Alzheimer's disease among people at heightened risk, according to a new study. In a paper published in Nature Medicine, Mass General Brigham ...

Nov 3, 2025

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76

Prenatal exposure to specific fine particles linked to autism risk

A multi-institutional team including Health Canada researchers has found that prenatal air exposure to specific particulate matter components and early-life ozone is associated with autism spectrum disorder in Ontario children.

Nov 3, 2025 report

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Tuesday, Nov 04

Analysis of 14 million children finds COVID-19 infection poses greater heart complication risk than vaccination

A new study shows children and young people face long-lasting and higher risks of rare heart and inflammatory complications after COVID-19 infection, compared to before or without an infection. Meanwhile, the COVID-19 vaccination ...

Nov 4, 2025

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211

Reactivating a fetal gene enables adult heart cells to regenerate after injury

Around the globe, heart disease remains one of the top causes of death. Once patients begin to suffer from serious heart problems, like heart attacks and heart failure, the heart muscles become damaged and are difficult to ...

Nov 4, 2025 report

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137

Sugars on immune cells, not just blood vessel walls, may regulate the inflammatory disease process

New research has updated the understanding of how sugars, known as glycans, help immune cells move into the skin in the inflammatory disease, psoriasis.

Nov 4, 2025

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107

Protein-based gel restores dental enamel and could advance tooth repair

Scientists from the University of Nottingham's School of Pharmacy and Department of Chemical and Environmental Engineering, in collaboration with an international team of researchers, have developed a bio-inspired material ...

Nov 4, 2025

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79

Social interactions help to form lasting memories, study finds

Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), have uncovered a previously overlooked role of the hippocampus in shaping memory, revealing how social interactions can ...

Nov 4, 2025

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75

Magnetized approach to kidney stone retrieval outperforms standard methods in preclinical study

Stanford University has unveiled a ureteroscopy-compatible device that magnetizes and retrieves kidney stone fragments with a wire, with performance in a pig model beating traditional removal techniques.

Nov 4, 2025 report

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74

Hair-thin fiber can control thousands of brain neurons simultaneously

Fiber-optic technology revolutionized the telecommunications industry and may soon do the same for brain research.

Nov 4, 2025

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Wednesday, Nov 05

Classification criteria for hemochromatosis arthropathy developed

The European Alliance of Associations for Rheumatology—has developed the first classification criteria for hemochromatosis arthropathy (HA) from a unique derivation cohort using rigorous methodology. HA is distinctive arthropathy ...

Nov 5, 2025

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272

Moderate to severe sleep apnea tied to higher risk of brain microbleeds

Research led by Korea University Ansan Hospital reports finding an association between moderate to severe obstructive sleep apnea and increased risk of cerebral microbleeds.

Nov 5, 2025 report

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68

Physical activity levels linked to risk for digestive system cancers

For digestive system cancers (DSCs), higher physical activity levels are associated with lower risk and mortality, according to a study published online Oct. 30 in JAMA Oncology.

Nov 5, 2025

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66

Using your phone every night before bed? Researchers say that's okay

Scrolling on your phone before bed may not be as bad for your sleep as we once thought. New research from Toronto Metropolitan University (TMU) and the Université Laval suggests nightly screen use does not contribute to ...

Nov 5, 2025

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57

Precision medicine intervention found to ease symptoms of a depression biotype

Depression is one of the most widespread mental health disorders worldwide, characterized by persistent feelings of sadness, a loss of interest in everyday activities, dysregulated sleep or eating patterns and other impairments. ...

Nov 5, 2025 feature

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The shortcomings of AI responses to mental health crises

Can you imagine someone in a mental health crisis—instead of calling a helpline—typing their desperate thoughts into an app window? This is happening more and more often in a world dominated by artificial intelligence. ...

Nov 5, 2025

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40

CRISPR screen identifies new regulator of androgen receptor in prostate cancer

A poorly characterized protein, historically thought to be a chaperon or enzyme, may actually be a key player in prostate cancer. In a systematic CRISPR screen, scientists from Arc Institute, UCSF, and the Fred Hutchinson ...

Nov 5, 2025

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Thursday, Nov 06

Brain-computer interface decodes Mandarin from neural signals in real time

Researchers in Shanghai have reported in a study, recently published in Science Advances, that they've successfully decoded Mandarin Chinese language in real time with the help of a brain-computer interface (BCI) framework, ...

Nov 6, 2025 report

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111

Why your daily walk might not work as well if you're on metformin

A widely prescribed diabetes drug may be sabotaging one of the most trusted strategies for preventing the disease: exercise.

Nov 6, 2025

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57

Meditation retreat rapidly reprograms body and mind, brain monitoring reveals

Researchers at the University of California San Diego have found that an intensive retreat combining multiple mind-body techniques, including meditation and healing practices, produced rapid and wide-ranging changes in brain ...

Nov 6, 2025

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48

Real-world responses reveal which patients benefit most from new schizophrenia drug

Each year, about 100,000 Americans experience psychosis, a serious condition that disrupts thoughts and perceptions so profoundly that it can distort a person's sense of reality.

Nov 6, 2025

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41

Sexual dysfunction in women at midlife explored by largest study of its kind

Almost 50% of women in midlife surveyed in a Monash University-led study had poor sexual well-being, including a doubling of the likelihood of desire and arousal dysfunction in early perimenopausal women from premenopause.

Nov 6, 2025

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41

Early-stage clinical trial demonstrates promise of intranasal influenza vaccine in generating broad immunity

Researchers at the University of Maryland School of Medicine's Center for Vaccine Development and Global Health (CVD) report encouraging results from an early phase clinical trial that found an experimental intranasal vaccine ...

Nov 6, 2025

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40

Lung cancer's earliest stages may be driven by inflammation

By creating high-resolution cellular and molecular visual maps of lung cancer before and during development, researchers at The University of Texas MD Anderson Cancer Center have discovered that the earliest stages of lung ...

Nov 6, 2025

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Friday, Nov 07

Women are three times more likely than men to get severe long COVID: Here's why

Research published today in Cell Reports Medicine reveals key biological differences that may explain why women with long COVID—especially those who develop chronic fatigue syndrome—tend to experience more severe and ...

Nov 7, 2025

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118

Disagreement between two kidney function tests predicts serious health problems

A mismatch between two common tests for kidney function may indicate a higher risk for kidney failure, heart disease, and death, a new study shows.

Nov 7, 2025

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78

Hot pants for good health: Scientists try heat therapy to lower blood pressure

The saying goes that you should stay out of the kitchen if you can't take the heat, but new research suggests otherwise—for the sake of your blood pressure.

Nov 7, 2025

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58

Coordinated brain network activity during emotional arousal may explain vivid, lasting memories

Past psychology studies suggest that people tend to remember emotional events, such as their wedding, the birth of a child or traumatic experiences, more vividly than neutral events, such as a routine professional meeting. ...

Nov 7, 2025 feature

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51

How colorectal cancer evades immunotherapy using a dual barrier

Colorectal cancer is one of the leading causes of cancer death worldwide. In recent years, immunotherapies—treatments that reactivate the immune system to attack tumor cells—have transformed the treatment of many types ...

Nov 7, 2025

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51

Urolithin A nudges aging immune cells toward a youthful profile in 28 days

An international research team focused on aging reports that urolithin A at 1,000 mg per day shifted human immune profiles toward a more naive-like, less exhausted CD8+ state and increased fatty acid oxidation capacity, with ...

Nov 7, 2025 report

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50

Chronic kidney disease is now the ninth leading cause of death, global analysis finds

Record numbers of men and women globally are now estimated to have reduced kidney function, a new study shows. Figures rose from 378 million people with the disease in 1990 to 788 million in 2023 as the world population grew ...

21 hours ago

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