Dose-volume histograms are obtained from regions of interest in RT dose maps. Dose-volume histogram parameters are important for, e.g. accepting treatment plans and prognosticating radiation-induced side effects.

Almost all of the underlying infrastructure is in place:

• MIRP can process dose maps and masks.
• MIRP has a flexible feature engine -- intensity-volume histogram (IVH) features are very similar in nature.

What would be needed is:

• A wrapper around extract_features_and_images that configures the general process for computing dose volume histogram parameters, and then computing dose volume histograms from the processed dose map. Yes, that's double work, but allows for making use of existing code flows.
• A variable that passes custom IVH features to allow the user to compute specific values.