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6 changes: 3 additions & 3 deletions conf/modules/annotate_genome_snvs.config
Original file line number Diff line number Diff line change
Expand Up @@ -77,10 +77,10 @@ process {

withName: '.*ANNOTATE_GENOME_SNVS:ENSEMBLVEP_SNV' {
ext.prefix = { "${vcf.simpleName}_rohann_vcfanno_filter_vep" }
ext.args = [
ext.args = { [
'--dir_plugins vep_cache/Plugins',
'--plugin LoFtool,LoFtool_scores.txt',
'--plugin pLI,pLI_values_107.txt',
'--plugin pLI,pLI_values.txt',
'--plugin SpliceAI,snv=spliceai_21_scores_raw_snv_-v1.3-.vcf.gz,indel=spliceai_21_scores_raw_snv_-v1.3-.vcf.gz',
'--distance 5000',
'--buffer_size 20000',
Expand All @@ -90,7 +90,7 @@ process {
'--hgvs --humdiv --no_progress --numbers',
'--merged --polyphen p --protein --offline --regulatory --sift p --symbol --tsl',
'--uniprot --vcf'
].join(' ')
].join(' ') }
}

withName: '.*ANNOTATE_GENOME_SNVS:BCFTOOLS_CONCAT' {
Expand Down
2 changes: 1 addition & 1 deletion conf/modules/annotate_mobile_elements.config
Original file line number Diff line number Diff line change
Expand Up @@ -40,7 +40,7 @@ process {
ext.args = { [
'--dir_cache vep_cache',
'--dir_plugins vep_cache/Plugins',
'--plugin pLI,pLI_values_107.txt',
'--plugin pLI,pLI_values.txt',
'--appris --biotype --buffer_size 100 --canonical --cache --ccds',
'--compress_output bgzip --distance 5000 --domains',
'--exclude_predicted --force_overwrite --format vcf',
Expand Down
6 changes: 3 additions & 3 deletions conf/modules/annotate_mt_snvs.config
Original file line number Diff line number Diff line change
Expand Up @@ -18,10 +18,10 @@
process {
if (!params.skip_mt_annotation) {
withName: '.*ANNOTATE_MT_SNVS:ENSEMBLVEP_MT' {
ext.args = [
ext.args = { [
'--dir_plugins vep_cache/Plugins',
'--plugin LoFtool,LoFtool_scores.txt',
'--plugin pLI,pLI_values_107.txt',
'--plugin pLI,pLI_values.txt',
'--plugin SpliceAI,snv=spliceai_21_scores_raw_snv_-v1.3-.vcf.gz,indel=spliceai_21_scores_raw_snv_-v1.3-.vcf.gz',
'--distance 0',
'--buffer_size 20000',
Expand All @@ -31,7 +31,7 @@ process {
'--hgvs --humdiv --no_progress --numbers',
'--merged --polyphen p --protein --offline --regulatory --sift p --symbol --tsl --vcf',
'--uniprot'
].join(' ')
].join(' ') }
}

withName: '.*ANNOTATE_MT_SNVS:ZIP_TABIX_HMTNOTE' {
Expand Down
6 changes: 3 additions & 3 deletions conf/modules/annotate_structural_variants.config
Original file line number Diff line number Diff line change
Expand Up @@ -43,18 +43,18 @@ process {
}

withName: '.*ANNOTATE_STRUCTURAL_VARIANTS:ENSEMBLVEP_SV' {
ext.args = [
ext.args = { [
'--dir_cache vep_cache',
'--dir_plugins vep_cache/Plugins',
'--plugin pLI,pLI_values_107.txt',
'--plugin pLI,pLI_values.txt',
'--appris --biotype --buffer_size 100 --canonical --cache --ccds',
'--compress_output bgzip --distance 5000 --domains',
'--exclude_predicted --force_overwrite --format vcf',
'--fork 4 --hgvs --humdiv --max_sv_size 248956422 --merged',
'--no_progress --numbers --per_gene --polyphen p',
'--protein --offline --regulatory --sift p',
'--symbol --tsl --uniprot --vcf'
].join(' ')
].join(' ') }
ext.prefix = { "${meta.id}_svdbquery_vep" }
publishDir = [
path: { "${params.outdir}/annotate_sv" },
Expand Down
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