Disease prevention articles from across Nature Portfolio

A synthetic peptide nanoparticle and microfluidic chip enable sterility testing of cell- and gene-based therapeutics in under 18 hours, bridging a long-standing safety gap for biopharmaceutical products that cannot undergo terminal sterilization and have limited shelf life.

Mahmud, Chang et al., model malaria transmission encompassing human mobility and epidemiological data in Bangladesh to guide elimination efforts. Local vector control efforts have the greatest impact when targeted to places with both high transmission intensity and high connectivity.

Burden of major disease is projected to increase in England and many other countries. Here the authors model the impact of reducing eight known risk factors for disease burden, such as BMI and smoking, between 2023-2043 in England and report that reductions in risk factors may not substantially reduce the major illness burden by 2043 due to population ageing.

In cognitively normal older adults at risk for Alzheimer’s dementia, physical inactivity was associated with faster tau protein buildup and cognitive decline.

Cholera remains a global health threat across the African continent. Here, the authors discuss the current issues relating to the control of the disease, and make recommendations for its management across Africa.

NotifAI-OS (notification artificial intelligence for opportunistic screening) is a conceptual deep learning-based framework that performs automated multi-target analysis of computed tomography examinations through quantitative tissue density and volumetric measurements to enable comprehensive disease screening during routine computed tomography examinations.

A synthetic peptide nanoparticle and microfluidic chip enable sterility testing of cell- and gene-based therapeutics in under 18 hours, bridging a long-standing safety gap for biopharmaceutical products that cannot undergo terminal sterilization and have limited shelf life.