Nature Search

Is the 1.5-ms pulsar a young neutron star?

John M. Blondin
Katherine Freese
Research30 Oct 1986
Nature

Volume: 323, P: 786-788
A toolbox for surfacing health equity harms and biases in large language models

Identifying a complex panel of bias dimensions to be evaluated, a framework is proposed to assess how prone large language models are to biased reasoning, with possible consequences on equity-related harms, and is applied to a large-scale and diverse user survey on Med-PaLM 2.

Stephen R. Pfohl
Heather Cole-Lewis
Karan Singhal
ResearchOpen Access23 Sept 2024
Nature Medicine

Volume: 30, P: 3590-3600
Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

Openshaw and colleagues find myeloid inflammation and complement activation signatures in patients with long COVID who were previously hospitalized.

Felicity Liew
Claudia Efstathiou
J. Eunice Zhang
ResearchOpen Access08 Apr 2024
Nature Immunology

Volume: 25, P: 607-621
Development and evaluation of deep learning models for cardiotocography interpretation

Nicole Chiou
Nichole Young-Lin
Mercy Asiedu
ResearchOpen Access08 Mar 2025
npj Women's Health

Volume: 3, P: 1-9
Expression and characterization of the cystic fibrosis transmembrane conductance regulator

Richard J. Gregory
Seng H. Cheng
Alan E. Smith
Research27 Sept 1990
Nature

Volume: 347, P: 382-386
The value of standards for health datasets in artificial intelligence-based applications

A systematic review, combined with a stakeholder survey, presents an overview of current practices and recommendations for dataset curation in health, with specific focuses on data diversity and artificial intelligence-based applications.

Anmol Arora
Joseph E. Alderman
Xiaoxuan Liu
ResearchOpen Access26 Oct 2023
Nature Medicine

Volume: 29, P: 2929-2938
Durability of single-dose HPV vaccination in young Kenyan women: randomized controlled trial 3-year results

In a prespecified 3-year analysis of the KEN SHE trial, single-dose HPV vaccination was shown to be well tolerated and provided durable protection against cervical HPV infection in Kenyan women aged 15–20 years.

Ruanne V. Barnabas
Elizabeth R. Brown
Torin T. Schaafsma
ResearchOpen Access04 Dec 2023
Nature Medicine

Volume: 29, P: 3224-3232
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes

Analyses of 2,658 whole genomes across 38 types of cancer identify the contribution of non-coding point mutations and structural variants to driving cancer.

Esther Rheinbay
Morten Muhlig Nielsen
Christian von Mering
ResearchOpen Access05 Feb 2020
Nature

Volume: 578, P: 102-111
Author Correction: Do no harm: a roadmap for responsible machine learning for health care

Jenna Wiens
Suchi Saria
Anna Goldenberg
Amendments and Corrections19 Sept 2019
Nature Medicine

Volume: 25, P: 1627
The ENIGMA-Neuroendocrinology working group to bridge gaps in female mental health research

We launched the ENIGMA-Neuroendocrinology working group with the aim to address knowledge gaps about the role of sex hormones in the brain, which lead to prevalent sex- and gender-based health disparities in biomedical research. We approach this by adopting a lifespan perspective to explore the interplay of hormonal dynamics and mental health in the brain.

Carina Heller
Claudia Barth
Nicole Petersen
Comments & Opinion27 Mar 2024
Nature Mental Health

Volume: 2, P: 348-350
Imaging magnetic focusing of coherent electron waves

Katherine E. Aidala
Robert E. Parrott
A. C. Gossard
Research03 Jun 2007
Nature Physics

Volume: 3, P: 464-468
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

Cognitive function is associated with health and important life outcomes. Here, the authors perform a genome-wide association study for general cognitive function in 300,486 individuals and identify genetic loci that implicate neural and cell developmental pathways in this trait.

Gail Davies
Max Lam
Ian J. Deary
ResearchOpen Access29 May 2018
Nature Communications

Volume: 9, P: 1-16
Massive computational acceleration by using neural networks to emulate mechanism-based biological models

Mechanistic models provide valuable insights, but large-scale simulations are computationally expensive. Here, the authors show that it is possible to explore the dynamics of a mechanistic model over a large set of parameters by training an artificial neural network on a smaller set of simulations.

Shangying Wang
Kai Fan
Lingchong You
ResearchOpen Access25 Sept 2019
Nature Communications

Volume: 10, P: 1-9
New insights into the genetic etiology of Alzheimer’s disease and related dementias

Meta-analysis of genome-wide association studies on Alzheimer’s disease and related dementias identifies new loci and enables generation of a new genetic risk score associated with the risk of future Alzheimer’s disease and dementia.

Céline Bellenguez
Fahri Küçükali
Jean-Charles Lambert
ResearchOpen Access04 Apr 2022
Nature Genetics

Volume: 54, P: 412-436
Functional composites by programming entropy-driven nanosheet growth

Following a micro-then-nano growth sequence to fabricate composites that are blends of block-copolymer-based supramolecules, small molecules and nanoparticles shows that high-performance barrier materials can be manufactured by means of entropy-driven assembly.

Emma Vargo
Le Ma
Ting Xu
Research08 Nov 2023
Nature

Volume: 623, P: 724-731
Temporal order of clinical and biomarker changes in familial frontotemporal dementia

Empirically based models of disease progression in familial frontotemporal dementia reveal the relative ordering of clinical, neuroimaging, and fluid biomarker changes and facilitate novel clinical trial designs

Adam M. Staffaroni
Melanie Quintana
Sónia Afonso
Research22 Sept 2022
Nature Medicine

Volume: 28, P: 2194-2206
Hormonal contraception alters vaginal microbiota and cytokines in South African adolescents in a randomized trial

Hormonal contraception may alter women’s susceptibility to HIV. Here, the authors report the results of a randomized clinical trial substudy assessing the effects of injectable Net-En, oral contraceptives (COC) and Nuvaring on vaginal microbiota and cytokines, associating COC with lower microbial diversity and Nuvaring with increased inflammation.

Christina Balle
Iyaloo N. Konstantinus
Heather B. Jaspan
ResearchOpen Access04 Nov 2020
Nature Communications

Volume: 11, P: 1-15
MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes

Antidepressant drugs are the most common treatment for depressive episodes but only a fraction of patients experience adequate response. Here the authors find dysregulation of miRNAs in peripheral blood samples from depressed patients after antidepressant treatment, and show that the miRNAs are regulators of psychiatrically relevant signalling pathways.

Juan Pablo Lopez
Laura M. Fiori
Gustavo Turecki
ResearchOpen Access22 May 2017
Nature Communications

Volume: 8, P: 1-12
An insula-frontostriatal network mediates flexible cognitive control by adaptively predicting changing control demands

The ability to continually adjust behavioural strategies is a hallmark of human cognition, yet the underlying mechanisms remain poorly understood. Here the authors show that an insula-frontostriatal network mediates such flexible cognitive control by adaptively predicting changing control demands.

Jiefeng Jiang
Jeffrey Beck
Tobias Egner
ResearchOpen Access22 Sept 2015
Nature Communications

Volume: 6, P: 1-11
Establishing the inter-rater reliability of spinal cord damage manual measurement using magnetic resonance imaging

David P. Cummins
Jordan R. Connor
Andrew C. Smith
Research18 Feb 2019
Spinal Cord Series and Cases

Volume: 5, P: 1-5
Do no harm: a roadmap for responsible machine learning for health care

In this Perspective, the authors present a framework, context and guidelines for accelerating the translation of machine-learning-based interventions in health care.

Jenna Wiens
Suchi Saria
Anna Goldenberg
Reviews19 Aug 2019
Nature Medicine

Volume: 25, P: 1337-1340
15q13.3 microdeletions increase risk of idiopathic generalized epilepsy

Thomas Sander and colleagues identify 15q13.3 microdeletions in 1% of individuals with idiopathic generalized epilepsy (IGE). The majority of these individuals do not show intellectual disability, schizophrenia or other neuropsychiatric phenotypes, thus extending the phenotypic spectrum associated with 15q13.3 microdeletions.

Ingo Helbig
Heather C Mefford
Thomas Sander
Research11 Jan 2009
Nature Genetics

Volume: 41, P: 160-162
SARS-CoV-2 viral load is associated with increased disease severity and mortality

In this study, Massachusetts Consortium for Pathogen Readiness (MassCPR) investigators assess the relationship between SARS-CoV-2 viral load and COVID-19 disease severity and report that the levels of detectable viral RNA, especially in plasma, correlates with severity of respiratory disease, inflammatory markers and predicted risk of death.

Jesse Fajnzylber
James Regan
Alex Zhu
ResearchOpen Access30 Oct 2020
Nature Communications

Volume: 11, P: 1-9
Tackling bias in AI health datasets through the STANDING Together initiative

Shaswath Ganapathi
Jo Palmer
Xiaoxuan Liu
Correspondence26 Sept 2022
Nature Medicine

Volume: 28, P: 2232-2233
Germline mutations in ETV6 are associated with thrombocytopenia, red cell macrocytosis and predisposition to lymphoblastic leukemia

Jorge Di Paola, Christopher Porter, Walter Kahr and colleagues report germline mutations in the transcriptional repressor gene ETV6 in three families with thrombocytopenia and elevated red blood cell volume. All three mutations affect the ability of ETV6 to repress transcription of a reporter construct, and the two protein-altering mutations affect megakaryocyte development.

Leila Noetzli
Richard W Lo
Jorge Di Paola
Research25 Mar 2015
Nature Genetics

Volume: 47, P: 535-538
Altering age and gender stereotypes by creating the Halo and Horns Effects with facial expressions

Mary Katherine Radeke
Anthony John Stahelski
ResearchOpen Access02 Jul 2020
Humanities and Social Sciences Communications

Volume: 7, P: 1-11
Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

Gail Davies
Max Lam
Ian J. Deary
Amendments and CorrectionsOpen Access01 May 2019
Nature Communications

Volume: 10, P: 1-5
Does the trip matter? Investigating the role of the subjective effects of psychedelics in persisting therapeutic effects

Katherine M. Nautiyal
David B. Yaden
Research18 Aug 2022
Neuropsychopharmacology

Volume: 48, P: 215-216
Implementation of a fully remote randomized clinical trial with cardiac monitoring

Mayfield et al. describe the implementation and feasibility of an exclusively remote randomized clinical trial of hydroxychloroquine and azithromycin for the treatment of COVID-19. The trial included monitoring of cardiovascular safety which was successfully done using digital technologies.

Jacob J. Mayfield
Neal A. Chatterjee
Arun R. Sridhar
ResearchOpen Access20 Dec 2021
Communications Medicine

Volume: 1, P: 1-10
A bacterial three-hybrid assay for forward and reverse genetic analysis of RNA–protein interactions

This protocol describes a three-hybrid system to analyze RNA–protein interactions in live bacteria and a complementary forward genetics screen to identify protein and RNA mutants with desired phenotypes.

Oliver M. Stockert
Chandra M. Gravel
Katherine E. Berry
Protocols23 Feb 2022
Nature Protocols

Volume: 17, P: 941-961

Search

Is the 1.5-ms pulsar a young neutron star?

A toolbox for surfacing health equity harms and biases in large language models

Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

Development and evaluation of deep learning models for cardiotocography interpretation

Expression and characterization of the cystic fibrosis transmembrane conductance regulator

The value of standards for health datasets in artificial intelligence-based applications

Durability of single-dose HPV vaccination in young Kenyan women: randomized controlled trial 3-year results

Analyses of non-coding somatic drivers in 2,658 cancer whole genomes

Author Correction: Do no harm: a roadmap for responsible machine learning for health care

The ENIGMA-Neuroendocrinology working group to bridge gaps in female mental health research

Imaging magnetic focusing of coherent electron waves

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

Massive computational acceleration by using neural networks to emulate mechanism-based biological models

New insights into the genetic etiology of Alzheimer’s disease and related dementias

Functional composites by programming entropy-driven nanosheet growth

Temporal order of clinical and biomarker changes in familial frontotemporal dementia

Hormonal contraception alters vaginal microbiota and cytokines in South African adolescents in a randomized trial

MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes

An insula-frontostriatal network mediates flexible cognitive control by adaptively predicting changing control demands

Establishing the inter-rater reliability of spinal cord damage manual measurement using magnetic resonance imaging

Do no harm: a roadmap for responsible machine learning for health care

15q13.3 microdeletions increase risk of idiopathic generalized epilepsy

SARS-CoV-2 viral load is associated with increased disease severity and mortality

Tackling bias in AI health datasets through the STANDING Together initiative

Germline mutations in ETV6 are associated with thrombocytopenia, red cell macrocytosis and predisposition to lymphoblastic leukemia

Altering age and gender stereotypes by creating the Halo and Horns Effects with facial expressions

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

Does the trip matter? Investigating the role of the subjective effects of psychedelics in persisting therapeutic effects

Implementation of a fully remote randomized clinical trial with cardiac monitoring

A bacterial three-hybrid assay for forward and reverse genetic analysis of RNA–protein interactions

Search

Quick links

Search

Filter By:

Search

Quick links