Nature Search

NAT10-mediated mRNA N⁴-acetylcytidine reprograms serine metabolism to drive leukaemogenesis and stemness in acute myeloid leukaemia

Zhang, Huang, Wang, Long et al. report that NAT10 enhances serine uptake and biosynthesis in an ac4C-dependent mechanism, thereby promoting stemness and progression in acute myeloid leukaemia.

Subo Zhang
Feng Huang
Huilin Huang
ResearchOpen Access06 Nov 2024
Nature Cell Biology

Volume: 26, P: 2168-2182
Understanding trends in electrochemical carbon dioxide reduction rates

Identifying trends in electrocatalytic activity for carbon dioxide reduction can help with catalyst design, but are difficult to define. Here, the authors develop an electrochemical kinetic model of the process, identifying scaling relations relating transition state energies to CO adsorption energy on metal surfaces.

Xinyan Liu
Jianping Xiao
Jens K. Nørskov
ResearchOpen Access22 May 2017
Nature Communications

Volume: 8, P: 1-7
High-κ dielectrics for advanced carbon-nanotube transistors and logic gates

Ali Javey
Hyoungsub Kim
Hongjie Dai
Research17 Nov 2002
Nature Materials

Volume: 1, P: 241-246
Maglev-fabricated long and biodegradable stent for interventional treatment of peripheral vessels

The interventional treatment of limb-threatening ischemia calls for a medical stent. Herein, a long and biodegradable stent appropriate for below-the-knee artery is developed based on a metal-polymer composite material, where a magnetic levitation is employed to achieve a homogeneous coating.

Wanqian Zhang
Xian Gao
Jiandong Ding
ResearchOpen Access10 Sept 2024
Nature Communications

Volume: 15, P: 1-13
A live-attenuated SARS-CoV-2 vaccine candidate with accessory protein deletions

A live-attenuated COVID vaccine could enrich the current vaccine portfolio. Here, Liu et al. engineer a live-attenuated SARS-CoV-2 vaccine candidate by deleting four viral accessory genes and show immunogenicity and protection in mice and hamsters.

Yang Liu
Xianwen Zhang
Pei-Yong Shi
ResearchOpen Access27 Jul 2022
Nature Communications

Volume: 13, P: 1-14
A multicenter clinical AI system study for detection and diagnosis of focal liver lesions

Early detection and accurate diagnosis of focal liver lesions are crucial for effective treatment and prognosis. Here, the authors present a fully automated diagnostic system that leverages multi-phase CT scans and clinical features, for diagnosing liver lesions.

Hanning Ying
Xiaoqing Liu
Xiujun Cai
ResearchOpen Access07 Feb 2024
Nature Communications

Volume: 15, P: 1-16
Efficacy of sialic acid supplementation in early life in autism model rats

Xiaolei Yang
Hongjuan Wei
Hongjie Li
ResearchOpen Access12 Mar 2025
Scientific Reports

Volume: 15, P: 1-14
Multi-shelled metal oxides prepared via an anion-adsorption mechanism for lithium-ion batteries

There is an intensive effort in developing multi-shelled metal oxide nanostructures for lithium-ion battery applications. Now, a metal anion-adsorption mechanism, as opposed to the conventional cation adsorption on carbonaceous templates, is demonstrated in the synthesis of vanadium oxide hollow microspheres, which exhibit excellent battery performance.

Jiangyan Wang
Hongjie Tang
Dan Wang
Research29 Apr 2016
Nature Energy

Volume: 1, P: 1-9
PIWI-interacting RNA expression regulates pathogenesis in a Caenorhabditis elegans model of Lewy body disease

piRNAs are small noncoding RNAs whose biological functions are not fully understood. Here, the authors demonstrate using C. elegans genetic models that dysregulated piRNAs are associated with protein degradation processes in a model of Lewy body disease.

Xiaobing Huang
Changliang Wang
Garry Wong
ResearchOpen Access02 Oct 2023
Nature Communications

Volume: 14, P: 1-15
Biomineral armor in leaf-cutter ants

Biomineral armour is known in a number of diverse creatures but has not previously been observed in insects. Here, the authors report on the discovery and characterization of high-magnesium calcite armour which overlays the exoskeletons of leaf-cutter ants.

Hongjie Li
Chang-Yu Sun
Cameron R. Currie
ResearchOpen Access24 Nov 2020
Nature Communications

Volume: 11, P: 1-11
Ballistic carbon nanotube field-effect transistors

Ali Javey
Jing Guo
Hongjie Dai
Research07 Aug 2003
Nature

Volume: 424, P: 654-657
Synthesis and characterization of carbide nanorods

Hongjie Dai
Eric W. Wong
Charles M. Lieber
Research29 Jun 1995
Nature

Volume: 375, P: 769-772
Emerging WS₂/montmorillonite composite nanosheets as an efficient hydrophilic photocatalyst for aqueous phase reactions

Kang Peng
Hongjie Wang
Xingyu Fan
ResearchOpen Access08 Nov 2019
Scientific Reports

Volume: 9, P: 1-9
Nickel isotopic evidence for late-stage accretion of Mercury-like differentiated planetary embryos

Based on Nickel isotope analysis of meteorites and terrestrial rocks, the authors suggest that the Bulk Silicate Earth has a sub-chondritic Nickel isotope composition. This signature is thought to result from the impact and accretion of a Mercury-like impactor which originated from the innermost Solar System.

Shui-Jiong Wang
Wenzhong Wang
Weihan Li
ResearchOpen Access12 Jan 2021
Nature Communications

Volume: 12, P: 1-7
Ultra-strong bio-glue from genetically engineered polypeptides

Biomedical glues often face a challenge in providing strong adhesion and providing remodelling capabilities. Here the authors report on the development of a biocompatible and biodegradable protein-based coacervate adhesive and demonstrate application in haemostasis and wound healing using pig models.

Chao Ma
Jing Sun
Andreas Herrmann
ResearchOpen Access14 Jun 2021
Nature Communications

Volume: 12, P: 1-14
Seroepidemiology of enterovirus A71 infection in prospective cohort studies of children in southern China, 2013-2018

Hand, foot and mouth disease, caused by enterovirus A71 (EV-A71) infection, is common in children in China. Here, the authors estimate EV-A71 incidence and seroprevalence using data from two longitudinal cohorts and find that, despite high infection rates, a large proportion of children under 6 are susceptible.

Juan Yang
Qiaohong Liao
Hongjie Yu
ResearchOpen Access26 Nov 2022
Nature Communications

Volume: 13, P: 1-10
Genetic analyses identify circulating genes related to brain structures associated with Parkinson’s disease

Zhe Han
Yanping Zhu
Fuyi Xu
ResearchOpen Access14 Jan 2025
npj Parkinson's Disease

Volume: 11, P: 1-11
TFEB–vacuolar ATPase signaling regulates lysosomal function and microglial activation in tauopathy

Wang et al. showed that genetic disruption of TFEB and v-ATPase-mediated lysosomal signaling leads to increased tau pathology but defective microglia activation, demonstrating an essential role of the lysosome in regulating microglia activity.

Baiping Wang
Heidi Martini-Stoica
Hui Zheng
Research20 Nov 2023
Nature Neuroscience

Volume: 27, P: 48-62
BNT162b2-elicited neutralization of Delta plus, Lambda, Mu, B.1.1.519, and Theta SARS-CoV-2 variants

Jianying Liu
Yang Liu
Pei-Yong Shi
ResearchOpen Access08 Apr 2022
npj Vaccines

Volume: 7, P: 1-4
An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction

The Asian lineage of Zika virus (ZIKV) has acquired a mutation in NS1 that enhances mosquito infection. Here, Xia et al. show that the same mutation interferes with interferon production through interaction with TBK1 and affects ZIKV replication in mice.

Hongjie Xia
Huanle Luo
Pei-Yong Shi
ResearchOpen Access29 Jan 2018
Nature Communications

Volume: 9, P: 1-13
Deciphering the impact of genomic variation on function

The Impact of Genomic Variation on Function Consortium is combining single-cell mapping, genomic perturbations and predictive modelling to investigate relationships between human genomic variation, genome function and phenotypes and will provide an open resource to the community.

Jesse M. Engreitz
Heather A. Lawson
Ella K. Samer
Reviews04 Sept 2024
Nature

Volume: 633, P: 47-57
The oncogene c-Jun impedes somatic cell reprogramming

Pei and colleagues report that the oncogene c-Jun acts as a somatic cell reprogramming barrier, and that its truncated dominant-negative form can substitute for Oct4 in reprogramming.

Jing Liu
Qingkai Han
Duanqing Pei
Research22 Jun 2015
Nature Cell Biology

Volume: 17, P: 856-867
Genome-wide association study in Chinese men identifies two new prostate cancer risk loci at 9q31.2 and 19q13.4

Yinghao Sun and colleagues report a genome-wide association study for prostate cancer in Han Chinese men. They identify two new risk-associated loci at chromosomes 9q31 and 19q13.

Jianfeng Xu
Zengnan Mo
Yinghao Sun
Research30 Sept 2012
Nature Genetics

Volume: 44, P: 1231-1235
Dual role of PID1 in regulating apoptosis induced by distinct anticancer-agents through AKT/Raf-1-dependent pathway in hepatocellular carcinoma

Jian Yang
Senlin Li
Ming Xiang
ResearchOpen Access28 Apr 2023
Cell Death Discovery

Volume: 9, P: 1-13
TGF-β1/IL-11/MEK/ERK signaling mediates senescence-associated pulmonary fibrosis in a stress-induced premature senescence model of Bmi-1 deficiency

Haiyun Chen
Hongjie Chen
Jianliang Jin
ResearchOpen Access21 Jan 2020
Experimental & Molecular Medicine

Volume: 52, P: 130-151
Transcriptional responses of wheat and the cereal cyst nematode Heterodera avenae during their early contact stage

Changlong Chen
Lei Cui
Hongjie Li
ResearchOpen Access03 Nov 2017
Scientific Reports

Volume: 7, P: 1-15
Vitamin C modulates TET1 function during somatic cell reprogramming

Guo-Liang Xu, Duanqing Pei and colleagues show that during induced pluripotent cell reprogramming Tet1 regulates 5-hydroxymethylcytosine levels at loci critical for mesenchymal-to-epithelial transition in a vitamin C–dependent fashion. They also show that Tet1 either enhances or inhibits somatic cell reprogramming, depending on the absence or presence of vitamin C, respectively.

Jiekai Chen
Lin Guo
Duanqing Pei
Research27 Oct 2013
Nature Genetics

Volume: 45, P: 1504-1509
Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus–related hepatocellular carcinoma

Long Yu and colleagues report a genome-wide association study for hepatitis B virus–related hepatocellular carcinoma (HBV-HCC). They report that genetic variants in STAT4 and HLA-DQ genes confer risk of HBV-HCC.

De-Ke Jiang
Jielin Sun
Long Yu
Research16 Dec 2012
Nature Genetics

Volume: 45, P: 72-75
Structure-based Design of JOC-x, a Conjugatable Tumor Tight Junction Opener to Enhance Cancer Therapy

Ragan Pitner
Jiho Kim
Sean A. Gray
ResearchOpen Access16 Apr 2019
Scientific Reports

Volume: 9, P: 1-13
RT-IVT method allows multiplex real-time quantification of in vitro transcriptional mRNA production

A new method (RT-IVT) leverages fluorescence quenchers & DNA ligase in FRET and RNA-splinted DNA ligation methods to allow inexpensive, nonradioactive and selective mRNA production quantification.

Fengyu Zhang
Yipeng Wang
Lichuan Gu
ResearchOpen Access24 Apr 2023
Communications Biology

Volume: 6, P: 1-11
Clean synthesis of Cu₂O@CeO₂ core@shell nanocubes with highly active interface

Strongly coupled and uniform Cu₂O@CeO₂ core@shell cubes with highly active interface are successfully fabricated via a ‘clean synthetic process’. The final hybrid nanostructure formation is highly dependent on the species of Cu precursors as well as the synthetic temperatures. Finally the as-obtained 155 nm cubes exhibit the highest catalytic activity in the catalytic CO oxidation and the peroxidase-like activity test.

Xiao Wang
Dapeng Liu
Hongjie Zhang
ResearchOpen Access23 Jan 2015
NPG Asia Materials

Volume: 7, P: e158
Grazing weakens competitive interactions between active methanotrophs and nitrifiers modulating greenhouse-gas emissions in grassland soils

Hong Pan
Haojie Feng
Jianming Xu
ResearchOpen Access09 Dec 2021
ISME Communications

Volume: 1, P: 1-12
Retinopathy of prematurity: risk stratification by gestational age

Tiffany Wu
Rakesh Rao
Margaret Reynolds
Research18 Jan 2023
Journal of Perinatology

Volume: 43, P: 694-701
The severity of NEC is ameliorated by prostaglandin E2 through regulating intestinal microcirculation

Dandan Mo
Chun Deng
Chunbao Guo
ResearchOpen Access17 Aug 2023
Scientific Reports

Volume: 13, P: 1-12
Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: metabolomics-informed genomics

Duan Liu
Balmiki Ray
Richard M. Weinshilboum
ResearchOpen Access10 Jan 2018
Translational Psychiatry

Volume: 8, P: 1-13
miR-19b downregulates intestinal SOCS3 to reduce intestinal inflammation in Crohn’s disease

Xiuqin Cheng
Xiaofei Zhang
Hongjie Zhang
ResearchOpen Access22 May 2015
Scientific Reports

Volume: 5, P: 1-15
A composite scaffold of MSC affinity peptide-modified demineralized bone matrix particles and chitosan hydrogel for cartilage regeneration

Qingyang Meng
Zhentao Man
Yingfang Ao
ResearchOpen Access03 Dec 2015
Scientific Reports

Volume: 5, P: 1-14
Core-shell VO₂@TiO₂ nanorods that combine thermochromic and photocatalytic properties for application as energy-saving smart coatings

Yamei Li
Shidong Ji
Minoru Kanehira
ResearchOpen Access02 Apr 2013
Scientific Reports

Volume: 3, P: 1-13
Chemical profiling analysis of Maca using UHPLC-ESI-Orbitrap MS coupled with UHPLC-ESI-QqQ MS and the neuroprotective study on its active ingredients

Yanyan Zhou
Peng Li
Baolin Bian
ResearchOpen Access17 Mar 2017
Scientific Reports

Volume: 7, P: 1-14
Nifuroxazide boosts the anticancer efficacy of palbociclib-induced senescence by dual inhibition of STAT3 and CDK2 in triple-negative breast cancer

Xianzhe Wang
Wei Shi
Xiuping Chen
ResearchOpen Access26 Sept 2023
Cell Death Discovery

Volume: 9, P: 1-10
CBX6 is negatively regulated by EZH2 and plays a potential tumor suppressor role in breast cancer

Houliang Deng
Xiaowen Guan
Gang Li
ResearchOpen Access17 Jan 2019
Scientific Reports

Volume: 9, P: 1-13
Multiple Myeloma DREAM Challenge reveals epigenetic regulator PHF19 as marker of aggressive disease

Mike J. Mason
Carolina Schinke
Justin Guinney
ResearchOpen Access14 Feb 2020
Leukemia

Volume: 34, P: 1866-1874
Hyperuricemia is associated with the progression of IgA nephropathy in children

Yuanyuan Xu
Xiaohong Zheng
Wen Li
Research13 Mar 2023
Pediatric Research

Volume: 94, P: 1057-1066
Acceleration of pancreatic tumorigenesis under immunosuppressive microenvironment induced by Reg3g overexpression

Xiulan Liu
Zhongshi Zhou
Ming Xiang
ResearchOpen Access07 Sept 2017
Cell Death & Disease

Volume: 8, P: e3033
Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases

Xi Chen
Yi Ba
Chen-Yu Zhang
Research02 Sept 2008
Cell Research

Volume: 18, P: 997-1006
Gastrointestinal stromal tumors (GISTs) arising in uncommon locations: clinicopathologic features and risk assessment of esophageal, colonic, and appendiceal GISTs

Shaomin Hu
Lindsay Alpert
John Hart
Research26 Oct 2021
Modern Pathology

Volume: 35, P: 554-563
GRIN1 mutation associated with intellectual disability alters NMDA receptor trafficking and function

Wenjuan Chen
Christine Shieh
Tyler Mark Pierson
Research23 Feb 2017
Journal of Human Genetics

Volume: 62, P: 589-597
Recent progress in the phase-transition mechanism and modulation of vanadium dioxide materials

In this article, we review the prototypical phase-transition material-VO₂, which undergoes structure and conductivity changes simultaneously. The recent progresses in the transition mechanism are also discussed. Besides, this work gives a comprehensive understanding of the phase-transition modulations, such as element doping, electric field (current and gating) and tensile/compression strain, as well as employing laser.

Zewei Shao
Xun Cao
Ping Jin
ReviewsOpen Access25 Jul 2018
NPG Asia Materials

Volume: 10, P: 581-605

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