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Showing 1–4 of 4 results
Advanced filters: Author: Emily Perotti Clear advanced filters

  • Self-reactive B cells that are anergic express mainly IgD, yet the function of IgD is not clear. Here the authors analyse primary B cells from mice to show that IgD signalling attenuates self-antigen induced gene expression and promotes survival of anergic B cells that might go on to reactivate to foreign antigens and mutate away from self-reactivity.

    • Zahra Sabouri
    • Samuel Perotti
    • Christopher C. Goodnow
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-11

  • Rapid extracellular antigen profiling of a cohort of 194 individuals infected with SARS-CoV-2 uncovers diverse autoantibody responses that affect COVID-19 disease severity, progression and clinical and immunological characteristics.

    • Eric Y. Wang
    • Tianyang Mao
    • Aaron M. Ring
    Research
    Nature
    Volume: 595, P: 283-288