Nature Search

Carcinogenicity testing of herbicide 2,4,5-trichlorophenoxyethanol containing dioxin and of pure dioxin in Swiss mice

K. TÓTH
SUSAN SOMFAI-RELLE
JUDIT BENCE
Research01 Apr 1979
Nature

Volume: 278, P: 548-549
High-efficiency base editing in the retina in primates and human tissues

A base-editing approach optimized to target the retina shows high editing rates in a mouse model of Stargardt disease, as well as in nonhuman primates and ex vivo human retinal explants, paving the way for potential clinical applications.

Alissa Muller
Jack Sullivan
Bence György
ResearchOpen Access08 Jan 2025
Nature Medicine

Volume: 31, P: 490-501
A base editor for correcting deafness

Base editing can correct the hearing-loss phenotype in mice harbouring a common mutation in the otoferlin gene.

Bence György
News & Views12 Aug 2024
Nature Biomedical Engineering

Volume: 9, P: 3-4
Emerging role of extracellular vesicles in inflammatory diseases

Extracellular vesicles are now thought to mediate inflammation and immunity by carrying PAMPs, DAMPs, autoantigens, microRNAs, cytokines and various metabolites and cellular components. In this Review, the authors put these findings in the context of rheumatic diseases and hint at the future of therapies that might use extracellular vesicles to modulate immune responses.

Edit I. Buzas
Bence György
Steffen Gay
Reviews18 Feb 2014
Nature Reviews Rheumatology

Volume: 10, P: 356-364
High levels of AAV vector integration into CRISPR-induced DNA breaks

In-depth characterization of adeno-associated virus (AAV)-mediated CRISPR delivery is still lacking. Here, the authors show high levels of integration into Cas9-induced double-strand breaks (DSBs) in therapeutically relevant genes in vivo.

Killian S. Hanlon
Benjamin P. Kleinstiver
Bence György
ResearchOpen Access30 Sept 2019
Nature Communications

Volume: 10, P: 1-11
Removal of dead fish eggs by Asellus aquaticus as a potential biological control in aquaculture

Balázs Kucska
Quyến Nguyễn Ngọc
Tamás Müller
ResearchOpen Access27 Mar 2024
Scientific Reports

Volume: 14, P: 1-11
Exosome-associated AAV2 vector mediates robust gene delivery into the murine retina upon intravitreal injection

Sarah J. Wassmer
Livia S. Carvalho
Casey A. Maguire
ResearchOpen Access31 Mar 2017
Scientific Reports

Volume: 7, P: 1-10
Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss

Screening of Cas9 and gRNA combinations identifies the variant SaCas9-KKH that selectively disrupts the mutant Tmc1/TMC1 allele that causes hearing loss, prevents deafness and preserves inner-ear hair cell function in Tmc1 mutant Beethoven mice.

Bence György
Carl Nist-Lund
David P. Corey
Research03 Jul 2019
Nature Medicine

Volume: 25, P: 1123-1130
PersonALL: a genetic scoring guide for personalized risk assessment in pediatric B-cell precursor acute lymphoblastic leukemia

Gábor Bedics
Bálint Egyed
Donát Alpár
ResearchOpen Access21 Jun 2023
British Journal of Cancer

Volume: 129, P: 455-465
Membrane-bound Gaussia luciferase as a tool to track shedding of membrane proteins from the surface of extracellular vesicles

Mikołaj Piotr Zaborowski
Pike See Cheah
Xandra O. Breakefield
ResearchOpen Access22 Nov 2019
Scientific Reports

Volume: 9, P: 1-16
Mutant torsinA in the heterozygous DYT1 state compromises HSV propagation in infected neurons and fibroblasts

Bence György
Lilian Cruz
Xandra O. Breakefield
ResearchOpen Access02 Feb 2018
Scientific Reports

Volume: 8, P: 1-11
Interplay between membrane active host defense peptides and heme modulates their assemblies and in vitro activity

Tünde Juhász
Mayra Quemé-Peña
Tamás Beke-Somfai
ResearchOpen Access15 Sept 2021
Scientific Reports

Volume: 11, P: 1-15

Search

Carcinogenicity testing of herbicide 2,4,5-trichlorophenoxyethanol containing dioxin and of pure dioxin in Swiss mice

High-efficiency base editing in the retina in primates and human tissues

A base editor for correcting deafness

Emerging role of extracellular vesicles in inflammatory diseases

High levels of AAV vector integration into CRISPR-induced DNA breaks

Removal of dead fish eggs by Asellus aquaticus as a potential biological control in aquaculture

Exosome-associated AAV2 vector mediates robust gene delivery into the murine retina upon intravitreal injection

Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss

PersonALL: a genetic scoring guide for personalized risk assessment in pediatric B-cell precursor acute lymphoblastic leukemia

Membrane-bound Gaussia luciferase as a tool to track shedding of membrane proteins from the surface of extracellular vesicles

Mutant torsinA in the heterozygous DYT1 state compromises HSV propagation in infected neurons and fibroblasts

Interplay between membrane active host defense peptides and heme modulates their assemblies and in vitro activity

Search

Quick links

Search

Filter By:

Search

Quick links