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The Japan Autophagy Consortium (JAPC) was established to support collaborative autophagy research and advance public understanding. By bridging basic research, product development and public engagement, the JAPC aims to create a sustainable foundation for autophagy-related innovation in both academic and commercial sectors.
The structural biology community in New York City combines expertise and access to cutting-edge instrumentation that fosters cooperation. Working collaboratively is indispensable because developing interdisciplinary tools can enable discoveries in cell, structural and molecular biology.
Doing science in Latin America can be as exciting as it is challenging. Starting my laboratory for transcription and epigenetics in Chile after working in the USA has required deep conviction and constant effort. It is a long-term project aimed at creating new opportunities for the next generation of Chilean scientists, offering Latin American perspectives to contribute to science.
We are delighted to introduce additional content types at Nature Structural & Molecular Biology, which allow us to offer more discussion of societal and scientific issues, better represent the unique perspectives of our readers, showcase their stories, and amplify their voices.
Exile, discovery, and resilience have shaped my journey as a group leader in Mexico. From exploring chromatin architecture to building a lab and community, this is how science became my vocation and my home.
Inhibitors of ferroptosis are key tools for studies of cell death and may ultimately prove useful for the treatment of various diseases. In this Comment, we discuss major types of ferroptosis inhibitors and considerations for their use in mechanistic and preclinical studies.
Post-translational modifications show mechanistic crosstalk, exemplified by the ADP-ribose–ubiquitin hybrid signal, in which one post-translational modification modifies another. This Comment highlights its discovery, mechanistic basis and functional consequences, and outlines critical questions for understanding this emerging signaling paradigm.
Returning to Central Europe was appealing and challenging. Here, I reflect on my part in rebuilding a research career in Czechia and fostering a collaborative scientific community across the region.
Francesca Mattiroli leads a research group at the Hubrecht Institute in Utrecht in the Netherlands, delving into the dynamics of chromatin during DNA synthesis. Here we ask her about her research ethos, experience and interests.
Yael David leads her lab focused on studying the fundamental mechanisms of epigenetic regulation of transcription at Memorial Sloan Kettering Cancer Center, and Charles Rice is the Maurice R. and Corinne P. Greenberg Professor in Virology at The Rockefeller University in New York City. We contacted them to discuss a recent publication by the David lab that substantially advances the molecular understanding of and, potentially, the clinical arsenal against infection with hepatitis B virus (HBV).
Returning to Brazil to establish a research laboratory was a decision fueled by hope, resilience, and the desire to create impact, despite ongoing challenges. Choosing to invest in science at home demands a deep personal commitment and a realistic view of the opportunities and obstacles ahead.
We outline a pilot starting at several Nature Portfolio journals aimed at improving and standardizing the reporting of light and fluorescence microscopy experiments.
Jerelle Joseph is an assistant professor at the Department of Chemical and Biological Engineering and the Omenn–Darling Bioengineering Institute at Princeton University in New Jersey. We contacted Jerelle to learn about her research priorities, along with her thoughts about the biomolecular condensates field and how computational biology and molecular simulations can fuel discovery.
