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Dulaglutide ameliorates hypertensive nephropathy in rats via preserving renal function’s biomarkers, restoring tissue redox balance, increasing the anti-inflammatory marker IL-10 and decreasing the inflammatory marker TNF-α, elevating the renoprotective PPARγ gene expression, amending renal vasculopathy and glomerular injury, decreasing fibrosis, and increasing the immunohistochemical expression of eNOS and VEGF.
This study evaluated the association between cumulative blood pressure (BP) load elevation during early pregnancy and the risk of low birth weight (LBW). Elevation of both cumulative systolic and diastolic BP load was associated with an increased risk of LBW, even when average BP remained within the normal range.
