The landmark discovery of the BCL-2 gene and its function marked the inhibition of apoptotic cell death as a crucial mechanism driving cancer development. This new review brings together some of the original researchers who describe the sequence of critical discoveries that led to drug development saving and improving tens of thousands of lives annually. Read only in Cell Death & Differentiation.

On behalf of the CDD Advisory Committee, we invite you to nominate a candidate for the 2025 CDD AWARD and CDD Jurg Tschopp PRIZE for career, achievement and excellence. Find out more in the link above.

Cell Death & Differentiation proudly celebrates 30 years of publication. 30 years and two sister journals later, what is next? The landscape of scientific communication is rapidly evolving with new challenges including AI, speed of discovery, social media, data sharing and accessibility, and the pervasive threat of misinformation. Read the full Editorial, written by the Editors, in the link above.

With sadness we share that “The Father of Apoptosis”, John F.R. Kerr, passed away on 4 June 2024, aged 90. Kerr was renowned for his inspirational contribution to education, cell death and giving a generation of medical students a solid understanding of the pathological basis of disease. The full obituary can be read in the Cell Death & Differentiation journal or click the link above.