Table 4 Results from regression models of ASAIR on the country-level

From: Country-level incidence of Alzheimer disease and related dementias is associated with increased omega-6-PUFA consumption

 

Change in ASAIR associated with a 1 unit increase in country-level lipid (β)

95% CI

p value

Omega-6 (% of energy intake) a

2.44

1.70, 3.19

1.38 × 10−9

Omega-3 (mg/day) a

-0.004

−0.010, 0.001

1.11 × 10−1

Gross National Income a

0.29

−1.341.92

7.28 × 10−1

Saturated Fat (% of energy intake) b

Below the threshold of 10

2.67

1.23, 4.11

5.71 × 10−4

Above the threshold of 10

0.04

−0.44, 0.53

8.62 × 10−1

Trans-Fat (% of energy intake) c

Below the threshold of 1.5

7.35

0.79, 13.90

2.96 × 10−2

Above the threshold of 1.5

0.70

−1.89, 3.29

6.03 × 10−1

Dietary Cholesterol (mg/day) d

Below the threshold of 250

0.15

0.07, 0.23

5.98 × 10−4

Above the threshold of 250

0.02

−0.03, 0.07

3.61 × 10−1

  1. aMultivariable model with omega-6, omega-3 (mg/day) and Gross National Income modeled with linear terms, and saturated fat, dietary cholesterol, and trans-fat were modeled with penalized splines (n = 183 countries).
  2. bThe same model as in a, but now with a linear term for saturated fat, and evaluated in two separate strata (above and below the threshold of 10% saturated fat by total energy intake).
  3. cThe same model as in a, but now with a linear term for trans-fat, and evaluated in two separate strata (above and below the threshold of 1.5% trans-fat by total energy intake).
  4. dThe same model as in a, but now with a linear term for dietary cholesterol, and evaluated in two separate strata (above and below the threshold of 250 mg/day of dietary cholesterol).
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