Fig. 9: Illustrative summary highlighting MOF-derived nanosystems designed for drug delivery, imaging, and synergistic therapeutic strategies.
From: 2D MOF structure, electrochemical biosensing in bioelectronic applications
A Schematic summary illustrates its application towards core-shell MOF (NP@MOF) nanostructures, focusing on the potential of magnetic, quantum dot (QD), gold (Au) and gadolinium (Gd) cores for applications in drug delivery, multimodal imaging and combined cancer therapies. 90. Copyright 2023 Elsevier, B Schematic summary illustration depicts a stimuli-responsive drug delivery system based on metal-organic frameworks (MOFs) 91. Copyright 2018 Wıley, C Schematic summary presents the application of Mn-doped Ti MOF nanosheets in microwave therapy and highlights their ability to achieve targeted tumor ablation, enhanced 1O2 production, improved T1 MRI contrast and successful treatment outcomes in HepG2 tumor models. 23. Copyright 2023 Elsevier, D Schematic summary shows the multifunctional design of CuS@Fe-MOF nanoplatforms including photothermal therapy, chemotherapy, MRI, LSPR enhancement and pH-sensitive DOX release. This integrated system provides effective tumor ablation through synergistic therapy while maintaining high biocompatibility, resulting in minimal side effects. 94. Copyright 2020 Elsevier.