Fig. 7: Illustrative summary of multifunctional MOFs designed for drug delivery, catalytic therapy, and bioactive molecule release.

A Schematic summary illustrates that incorporating ZIF-8 into PUG bioink improves structural stability and modulus, although excessive amounts of ZIF-8 may reduce cell viability 76. Copyright 2021 American Chemical Society, B Schematic summary, it illustrates the encapsulation of Cu-MOF nanoparticles within PCL, which enhances the stability of Cu-MOF in serum and supports sustained NO catalytic activity. This is validated by in vitro assays and in-situ implantation models 79. Copyright 2021 Elsevier, C Schematic summary highlights advances in the synthesis of micro- and nano-sized MIL-100 (Fe), examines its physicochemical stability under varying pH, temperature and physiological environments, and illustrates interactions in its biomedical uses, including biosensing, phototherapy, encapsulation techniques and drug delivery 80. Copyright 2021 Elsevier, D Schematic overview illustrates carbon monoxide delivery using bioactive zinc metal-organic frameworks, inspired by organisms’ self-repair processes. This method highlights cellular communication and promotes cooperative interactions for enhanced effectiveness. 81. Copyright 2023 Elsevier.