Supplementary Figure 1: Quantile–quantile plot of the observed P values on those expected for each genetic variants association with depression in our meta-analysis (n = 807,553 individuals).
P-values were obtained from an inverse-variance weighted meta-analysis of summary statistics data from UK Biobank, Psychiatric Genomics Consortium and 23andMe. UK Biobank summary statistics were obtained using a linear association analysis with the results transformed to the logistic scale. Psychiatric Genomics Consortium and 23andMe data were analysed using an additive logistic model. All association analyses were two-sided tests.