Extended Data Fig. 7: CD8+ TILs share features of exhaustion, but not Type 17 signature with colonic IL26+ cells.
From: Single-cell atlas of colonic CD8+ T cells in ulcerative colitis
a, Hierarchical clustering of CD8+ sub-populations detected in UC (cells from n = 3 donors) together with CD8+ sub-populations detected in liver cancer tumor-infiltrating lymphocytes (TILs) (left) (cells from n = 6 donors), colorectal cancer TILs (middle)(cells from n = 11 donors) and breast cancer TILs (right) (cells from n = 1 donor). b, Boxplot showing expression of selected exhaustion (top panels) and Type-17/ILC3 (bottom panels) signature genes in colonic CD8+ populations and tumour CD8+ TILs. Boxplots show the median, first and third quartiles, 5th percentile as minima and 95th percentile as maxima.